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All Journal The Journal of Experimental Life Sciences (JELS) Journal of Indonesian Tourism and Development Studies JURNAL LENTERA : Kajian Keagamaan, Keilmuan dan Teknologi Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ JOPS (Journal Of Pharmacy and Science) Jurnal Mandala Pharmacon Indonesia Fullerene Journal of Chemistry Jurnal Abdi Insani Lumbung Farmasi : Jurnal Ilmu Kefarmasian FORTE JOURNAL Indonesian Journal of Health Science Inspirasi: Jurnal Pengabdian dan Pemberdayaan Masyarakat Media Bina Ilmiah Journal of Research Applications in Community Services Journal of Pharmaceutical and Sciences. FASKES : Jurnal Farmasi, Kesehatan, dan Sains Jurnal Pharmacia Mandala Waluya International Journal of Education and Learning
Nawafila Februyani
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Evaluasi Kadar Protein Proses Produksi Protein Bar Daun Kelor (Moringa oleifera L.) Dengan Metode Kjeldahl Inggria Eka Pawestri; Nawafila Februyani; Ainu Zuhriyah
Jurnal Pharmacia Mandala Waluya Vol. 5 No. 3 (2026): Jurnal Pharmacia Mandala Waluya
Publisher : Prodi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54883/jpmw.v5i3.682

Abstract

Daun kelor (Moringa oleifera L.) merupakan tanaman lokal yang kaya protein dan berpotensi dikembangkan sebagaipangan fungsional. Penelitian ini bertujuan untuk menganalisis dan membandingkan kadar protein pada serbuk daunkelor dan produk protein bar berbasis daun kelor menggunakan metode Kjeldahl. Penelitian menggunakan desaineksperimental laboratorium dengan Rancangan Acak Lengkap (RAL) satu faktor, yaitu konsentrasi serbuk daun kelor pada formulasi protein bar yang terdiri atas F0 (0%), F1 (10%), F2 (15%), dan F3 (20%) dengan tiga kali replikasi. Analisis kadar protein dilakukan melalui tahapan destruksi, destilasi, dan titrasi metode Kjeldahl, kemudian data dianalisis menggunakan uji One-Way ANOVA. Hasil penelitian menunjukkan bahwa serbuk daun kelor memiliki kadar nitrogen sebesar 3,17% dan kadar protein sebesar 19,82%. Pada protein bar, kadar protein meningkat seiring penambahan konsentrasi serbuk daun kelor, yaitu F0 sebesar 7,12%, F1 sebesar 8,2%, F2 sebesar 8,61%, dan F3 sebesar 9,14%. Hasil organoleptik menunjukkan bahwa penambahan serbuk daun kelor memengaruhi warna dan aroma produk, namun tidak memengaruhi tekstur. Uji normalitas menunjukkan data berdistribusi normal, sedangkan uji homogenitas menunjukkan data tidak homogen sehingga analisis lanjut menggunakan metode Games-Howell. Hasil uji One-Way ANOVA menunjukkan adanya perbedaan signifikan antar perlakuan (p<0,05). Berdasarkan hasil penelitian, penambahan serbuk daun kelor terbukti meningkatkan kadar protein protein bar dan berpotensi dikembangkan sebagai pangan fungsional tinggi protein berbasis bahan lokal.
Efektivitas Timolol 0,5% dalam Menurunkan Tekanan Intraokular dan Meningkatkan Kualitas Hidup Pasien Glaukoma di Klinik Mata Dr. Haryo Bojonegoro: The Effectiveness of 0.5% Timolol in Reducing Intraocular Pressure and Improving the Quality of Life of Glaucoma Patients at Dr. Haryo Eye Clinic, Bojonegoro Irma Hidayah; Nawafila Februyani; Ainu Zuhriyah
JURNAL FARMASI DAN MAKANAN Vol 8 No 2 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i2.6219

Abstract

Glaucoma is one of the leading causes of sensory disability and irreversible blindness worldwide. This study aims to analyze the effectiveness of 0.5% Timolol in reducing intraocular pressure and its impact on the quality of life of glaucoma patients at Dr. Haryo Eye Clinic, Bojonegoro, in 2024. The research method used is the Retrospective-Prospective research method using primary and secondary data, involving 57 patients as samples. The study was conducted in March 2025. Statistical analysis of the effectiveness of 0.5% Timolol was carried out using paired-samples t-test and simple linear regression analysis. The results showed that of the 57 respondents, 47.4% were male and 52.6% were female, with the most common age group being 58–67 years (40.3%). The average percentage of intraocular pressure (IOP) reduction among glaucoma patients using 0.5% Timolol was 9.12%, and it showed an influence in improving quality of life by 17%. The ANOVA test revealed a significance value of 0.001, which is below the alpha significance level of <0.05.The conclusion of this research is 0.5% Timolol is effective in reducing intraocular pressure with an average reduction of 9.12% and has an influence in improving the quality of life of glaucoma patients by 17%.
Uji Karakteristik Fisik dan Aktivitas Antioksidan Sediaan Face Mist Berbasis Ekstrak Daun Tapak Dara (Catharanthus roseus L.) Yani&#039; Qoriati; Akhmad Al-bari; Nawafila Februyani
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 7, No 2 (2026): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v7i2.40081

Abstract

Kulit rentan mengalami kerusakan yang diakibatkan paparan radikal bebas yang dapat mengakibatkan stres oksidatif dan penuaan dini sehingga diperlukan antioksidan dalam sediaan topikal. Salah satu tanaman yang memiliki potensi antioksidan alami yaitu tapak dara (Catharanthus roseus L.) karena mengandung flavonoid, fenolik, dan alkaloid. Penelitian ini bertujuan untuk formulasi ekstrak daun tapak dara pada sediaan face mist dengan menguji karakteristik fisik dan tingkat aktivitas antioksidannya. Ekstrak didapat dengan ekstraksi ultrasonik menggunakan pelarut etanol 70% dan diformulasikan dalam tiga konsentrasi ekstrak yaitu 0,5, 1, dan 1,5 gram. Evaluasi meliputi uji organoleptik, pH, daya semprot, waktu kering, homogenitas, kelembapan kulit, bobot jenis, viskositas, dan aktivitas antioksidan metode DPPH. Hasil penelitian menunjukkan seluruh formula memenuhi persyaratan sediaan face mist dengan pH 4,6–5,0, daya semprot 5,3–7 cm, waktu kering kurang dari 5 menit, dan homogen. Formula F3 memberikan peningkatan kelembapan kulit tertinggi sebesar 60% serta aktivitas antioksidan terbaik dengan nilai IC50 108,10 ppm. Penelitian ini menunjukkan bahwa peningkatan konsentrasi ekstrak tapak dara meningkatkan aktivitas antioksidan sediaan face mist.
Physical Education Students' Perceptions Of The Use Of Supplements And Drugs In The World Of Sports Olivia Dwi Cahyani; Nawafila Februyani; Ria indah Kusuma Pitaloka
International Journal of Education and Learning Vol. 1 No. 1 (2025): Vol 1 No 1 June 2025
Publisher : Badan Usaha Milik Desa Berkaho Pungpungan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The use of supplements and medications in the world of sports has become an increasingly prominent issue, including among Physical Education students. A lack of proper understanding regarding the content, benefits, and risks of these substances can lead to dangerous misconceptions in sports practice. This study aims to examine the perceptions of Physical Education students at Nahdlatul Ulama Sunan Giri University regarding the use of supplements and medications in sports, as well as the factors that influence those perceptions. The research employs a descriptive qualitative approach with a field study method. Data were collected through in-depth interviews, observations, and documentation involving six purposively selected informants. The results show that students tend to be permissive toward the use of supplements and morally reject the use of medications; however, their understanding remains limited in terms of scientific and regulatory aspects. Factors influencing their perceptions include personal experience, peer influence, social media, and the limited coverage of the topic in academic courses. These findings highlight the need to strengthen the curriculum and health education to foster critical understanding and responsible attitudes regarding the use of performance-enhancing substances in sports.
Formulasi dan Karakterisasi Jamu Serbuk Instan Tinospora crispa dan Citrus aurantifolia dengan Eksipien Taste Masking Rosyfiana Syafi'i Salma; Nawafila Februyani; Abdul Basith
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1673

Abstract

Tinospora crispa has a dominant bitter taste and therefore requires formulation strategies to improve palatability. This preliminary study formulated instant herbal powder containing Tinospora crispa and Citrus aurantifolia with graded ratios of maltodextrin and sucrose and evaluated its initial physical characteristics and exploratory sensory response. A one-factor completely randomized design comprised three formulas, each prepared in triplicate for physical testing. Evaluations included organoleptic properties, visual homogeneity, flow time, flow rate, angle of repose, moisture content, dissolution time, pH, and an exploratory hedonic assessment involving seven untrained panelists. Numerical physical data were analyzed by one-way ANOVA followed by Tukey HSD when significant, while sensory scores were analyzed using the Friedman test followed by Wilcoxon signed-rank tests with Bonferroni correction. All formulas were fine, visually homogeneous powders with a pH of 5 and moisture content of 2.50-3.67%. The excipient ratio significantly affected angle of repose and moisture content. Friedman testing indicated global differences in taste and overall acceptance, but no formula pair remained significant after Bonferroni correction. No single formula was optimal across all physical parameters. F3 showed the highest descriptive scores for taste and overall acceptance and the fastest flow time, but this tendency cannot be generalized because of the small exploratory panel and incomplete raw-material, chemical, particle-size, and stability characterization.
Potensi Antidiabetes Teh Celup Ekstrak Tinospora crispa (L.) dan Stevia rebaudiana Menggunakan Teknik Co-Processing Granulasi Basah Alfiatul Khasanah; Nawafila Februyani; Atika Nirmala
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1679

Abstract

Introduction: Diabetes mellitus is a chronic metabolic disorder requiring practical herbal therapies with controlled physical quality. Tinospora crispa (L.) is known to possess antidiabetic potential through its alkaloid, flavonoid, and terpenoid constituents, while Stevia rebaudiana serves as a natural low-calorie sweetener and may offer additional metabolic benefits. This study aimed to evaluate the physical characteristics and antidiabetic potential of tea bags containing a combination of Tinospora crispa (L.) extract and Stevia rebaudiana powder prepared using wet-granulation co-processing technique. Methods: Three formulations were developed with varying concentrations of Tinospora crispa (L.) extract at 5%, 10%, and 15%. Extraction was performed using an ultrasonic-assisted method with 70% ethanol as solvent. Physical quality evaluation included moisture content, weight uniformity, brewing time, infusion pH, and homogeneity. An exploratory in vivo test was conducted on 15 alloxan-induced Swiss Webster mice (n=3 per group) over 7 days. Statistical analysis employed One-Way ANOVA followed by Tukey HSD test at α=0.05 significance level. Results: The extract yield was 39.07%. All formulations demonstrated homogeneity with uniform fill weight of 2 g per bag. Significant differences among formulations were observed in moisture content (*p*=0.001; η²=0.895), brewing time (*p*=0.006; η²=0.822), and infusion pH (*p*=0.031; η²=0.687). In the in vivo study, the positive control and all formulation groups showed a tendency toward decreasing blood glucose levels, whereas the negative control group exceeded the glucometer detection limit (>500 mg/dL) from day 5 to day 7. The formulation containing 10% extract (F2) demonstrated the largest descriptive reduction from 210.67 to 88.00 mg/dL (58.23%). Conclusion: Variations in Tinospora crispa (L.) extract concentration affected several physical quality parameters; however, no single formulation was superior across all tested parameters. The in vivo findings suggest a tendency toward antidiabetic activity, yet further studies with larger sample sizes, placebo controls, active compound standardization, and safety evaluations are required to confirm efficacy and elucidate the mechanism of action.
Co-Authors Abdul Basith Abdul Basith Ade M.C. Rohie Ade M.C. Rohie Agus Sholahudin Shidiq Ahmad Abil Kamal Ahmad Rifqi Azmi Ainu Zuhriyah Ainu Zuhriyah Ajeng pratiwi, Shoffi Akhmad Al-Bari Alfiatul Khasanah Almufida, Aulia Atika Nirmala Bintari Anggi Dwi Sugiarti Delsya Arfatadiya Khoiroh Dina Fitriani Dinda Intan Pramesti Ilmi, Moh. Mu'alliful Inggria Eka Pawestri Irma Hidayah Ita Aristia Sa'ida Kusuma, Ria Lisa Aminatul Mukaromah M. Choyim Al Amin Maic A.L. Sihombing Maic A.L. Sihombing Maysatun, Siti Nur Mohd Izzudin Muhammad Imron Muhimmatul Khoiriyah Musthofa, Mochamad Charis Nafisah, Roihanatun Nely Alfiana Faricha Alfiana Faricha Ni'am, Musfirotun Nurin Chasanah Nurul Huda Nurul Huda Olivia Dwi Cahyani Prawestri, Inggria Eka Putri Atika Julianti Putri, Rahma Putri, Wahyu Setia Kuscahyaning Rahayu, Yuni Puji Ria Indah Kusuma Pitaloka Rosalina E. Swandayani Rosalina Edy Swandayani Rosyfiana Syafi'i Salma Rosyida Kuayyisin Nafi Sahri Sahri Saputri, Romadhiyana Kisno Serafinah Indriyani Sugito, Mar’atus Sholikhah Titi Agni Hutahaen Valentina Aprilia Sunday Wahyu Widoretno Wulandari, Vilisa Ayu Dwi Wulansari, Imelia Yani’ Qoriati Yulianti Yulianti