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All Journal Althea Medical Journal Jurnal Berkala Epidemiologi Damianus Journal of Medicine The Indonesian Journal of Public Health Universa Medicina JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) Berkala Ilmiah Kedokteran Duta Wacana Jurnal Ilmu Kesehatan Masyarakat (The Public Health Science Journal) Oto Rhino Laryngologica Indonesiana Majalah Kedokteran Neurosains Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Indonesian Journal of Global Health research Cermin Dunia Kedokteran Berita Kedokteran Masyarakat Neurona Jurnal Kedokteran Meditek Jurnal Ilmu Kesehatan Masyarakat (The Public Health Science Journal) Cermin Dunia Kedokteran
Yvonne Suzy Handajani
Departemen Ilmu Kesehatan Masyarakat Dan Gizi, Fakultas Kedokteran Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Dari Lemak ke Sendi: Bahaya Proporsi Lemak Tubuh sebagai Penyebab Osteoartritis Lutut Kwok, Lyvia Ariella; Kristian, Kevin; Handajani, Yvonne Suzy; Barus, Jimmy Fransisco Abadinta
Jurnal Kedokteran Meditek Vol 31 No 5 (2025): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i5.3495

Abstract

Introduction: As individuals age, the incidence of osteoarthritis increases. Globally, it is reported that approximately 300 million individuals, particularly the elderly, are affected by osteoarthritis. Metabolic disorders related to lipid pathways have been associated with the development of osteoarthritis in the elderly. Purpose: This study aims to provide an overview of the relationship between haematological indicators, lipid profiles, and body fat proportion with osteoarthritis in the elderly population in Pusaka Kebon Jeruk, West Jakarta. Methods: This study used a cross-sectional design involving an elderly population, with 100 respondents aged ≥60 years who were willing to participate. Data were collected through interviews using an osteoarthritis questionnaire, blood draws, and measurements using BIA. The chi-square test (p<0.05) and multiple logistic regression (p<0.25) were used in this study. Results: Of the 100 respondents, it was found that 28% of the elderly respondents experienced osteoarthritis. Bivariate analysis showed a significant relationship between body fat proportion and osteoarthritis (p: 0.006; OR: 3.519; 95% CI: 1.394–8.878). Multivariate analysis indicated that body fat proportion was the dominant factor associated with osteoarthritis (p: 0.006; OR: 3.814; 95% CI: 1.475–9.865). Conclusions: We concluded that body fat proportion has a significant relationship with the incidence of osteoarthritis. However, this study did not find any significant associations between hemoglobin, white blood cells, RDW, LDL, HDL, triglycerides, and cholesterol.
Effect of cognitive stimulation therapy in combination with other intervention modalities on cognitive ability in elderly with cognitive impairment: a quasi-experimental study Turana, Yuda; Sani, Tara Puspitarini; Prasetya, Virginia Geraldine Hanny; Suswanti, Ika; Konny, Lisye; Halim, Magdalena Surjaningsih; Handajani, Yvonne Suzy
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.13-19

Abstract

BackgroundCognitive stimulation therapy (CST) has been proven to be beneficial in improving cognition and quality of life in people with mild cognitive impairment (MCI) and mild dementia (MD). This study investigates the benefit of more frequent exclusively CST intervention compared to less-frequent CST-exercise combination on cognitive ability among elderly people with cognitive impairment. MethodsA quasi-experimental controlled study involving 22 subjects aged = 60 years with cognitive impairment. They were divided into three groups: group A (6 months, weekly CST + exercise sessions, n=13), Group B (3 months, twice-weekly CST-only sessions, n=5), group C (3 months, no intervention, n=4) as control. The Modified Mini Mental State Examination Indonesian Version was used for evaluating the cognitive ability of the elderly subjects. Data were analyzed using one-way Anova and Kruskal-Wallis tests ResultsAll participants completed the study, the majority being female with mean age of 70.43 ± 6.97 years and differences in education level distribution across the three groups. The scores before and after the intervention showed a significant difference in the registration and construction domains (p<0.005). However, there was a greater improvement of the mean difference in cognitive scores in groups A and B compared to the control group, although the difference was not statistically significant (p >0.05). ConclusionA twice-weekly CST-only intervention and a once-a-week CST-exercise combination provide better cognitive improvement than no intervention (control). Therefore, elderly people with cognitive impairment should be encouraged to engage in physical activities, brain training, and group activities for promoting the brain’s ability.
Analisis Determinan Kejadian Hipertensi pada Lansia di Urban Jakarta Pakpahan, Hotmaria Agustina; Rahardjo, Tri Budi; Kridawati, Atik; Handajani, Yvonne Suzy
Jurnal Ilmu Kesehatan Masyarakat Vol. 13 No. 01 (2024): Jurnal Ilmu Kesehatan Masyarakat
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikm.v13i01.2566

Abstract

Hipertensi merupakan salah satu faktor risiko utama penyakit kardiovaskular dengan tingkat kejadian yang masih tinggi di dunia. Di negara-negara yang sedang berkembang, penyakit tidak menular seperti penyakit jantung, penyakit ginjal, stroke dan diabetes akan segera menggantikan penyakit menular dan malnutrisi sebagai penyebab kematian dan disabilitas. Data surveillans DKI Jakarta tahun 2019 menyebutkan peningkatan penyakit hipertensi dan diabetes di Jakarta masih sangat tinggi. Penelitian ini bertujuan untuk menentukan risiko yang paling signifikan terhadap kejadian hipertensi pada lansia. Penelitian ini adalah penelitian observasional analitik dengan metode penelitian kasus kontrol. Pengambilan sampel dilakukan dengan cara cluster random sampling, dengan jumlah sampel 91 kasus dan 91 kontrol pada kelompok lansia yang berusia ≥ 60 tahun. Data dianalisis dengan uji Chi-Square dan uji regresi logistik ganda. Hasil penelitian menunjukkan bahwa faktor depresi (nilai p = 0,0001; OR = 33,341), pendidikan (nilai p = 0,0001; OR = 6,276), dukungan keluarga (nilai p = 0,035; OR = 3,457), obesitas (nilai p = 0,028; OR = 0,321), riwayat keluarga (nilai p = 0,444; OR = 0,305), mengonsumsi makanan asin (nilai p = 0,002; OR = 0,195) berhubungan dengan kejadian hipertensi pada lansia. Kejadian hipertensi pada lansia di Jakarta beresiko lebih tinggi pada lansia dengan depresi, pendidikan rendah, dan kurangnya dukungan dalam keluarga, namun cenderung beresiko lebih rendah pada lansia dengan obesitas, riwayat keluarga hipertensi, dan kebiasan mengonsumsi makanan asin.
THE ROLE OF FUNCTIONAL ABILITY, MULTIMORBIDITY, AND DEPRESSION TO QUALITY OF LIFE OF INDONESIAN OLDER ADULTS Handajani, Yvonne Suzy; Vinsalia, Thania; Schröder-Butterfill, Elisabeth; Turana, Yuda
The Indonesian Journal of Public Health Vol. 20 No. 3 (2025): THE INDONESIAN JOURNAL OF PUBLIC HEALTH
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijph.v20i3.2025.538-551

Abstract

Introduction: Multimorbidity significantly affects older adults' quality of life (QoL). Its prevalence among adults aged ≥60 years ranges from 24% to 83%, increases with age and is closely linked to progressive physical and functional decline. A|ims: To investigate the determinants of QoL among community-dwelling older adults in urban Jakarta, Indonesia. Methods: A cross-sectional study was conducted in several community-based home care centers in West Jakarta, Indonesia, in 2023. From a database of 2,000 older adults, 600 individuals were selected using simple random sampling for screening. After applying inclusion and exclusion criteria, 501 older adults aged ≥60 years were included in the analysis. Sociodemographic and health-related data were collected using structured interviews and direct measurements. Mult|ivar|iate log|ist|ic regress|ion analysis was performed to identify factors associated with QoL. Results: A total of 501 older adults were analyzed; most were female (67.1%) and had multimorbidity (85.6%). The mean WHOQOL-BREF scores exceeded 60, with the highest score in the psychological domain (66.8). Physical health was significantly associated with multimorbidity (OR=2.08; p=0.013), exercise (OR=1.51; p=0.029), IADL (OR=3.54; p=0.007), ADL (OR=1.69; p=0.021), and balance (OR=1.92; p=0.044). Exercise increased the likelihood of better QoL (OR=1.47; p=0.037), while depression predicted poorer quality of life (OR=1.75; p=0.020). Conclusion: Multimorbidity, functional disability, balance impairment, depression, age, and exercise were significantly associated with QoL. Improving chronic disease management, maintaining independence, promoting regular exercise, and supporting mental health can enhance older adults’ well-being. Community-based programs encouraging active lifestyles and balance training may further improve QoL in this population.
Pengaruh Fungsi Kognitif Spesifik terhadap Risiko Frailty pada Lansia Budhy, Carissa Marvella; Turana, Yuda; Handajani, Yvonne Suzy; Kristian, Kevin
Bahasa Indonesia Vol 24 No 3 (2025): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v24i3.6155

Abstract

Pendahuluan: Penuaan populasi menyebabkan beban kesehatan meningkat, salah satunya adalah frailty. Berdasarkan systematic review dan meta-analysis pada 2023 prevalensi frailty pada lansia di Indonesia adalah 26,8%, sedangkan 55,5% mengalami pre-frail. Penelitian ini bertujuan untuk memeroleh gambaran tentang frailty serta faktor risikonya di Pusaka Kebon Jeruk, Jakarta Barat. Metode: Penelitian ini menggunakan rancangan potong-lintang dan melibatkan 100 responden berusia ≥60 tahun. Pengumpulan data dilakukan melalui wawancara dengan menggunakan, seperti Fried Fraily Index, MoCA-Ina, dan CERAD-NB. Analisis data dilakukan dengan metode chi-square dan multiple logistic regression. Hasil: Dari 100 responden, terdapat 75 (75% subjek) berusia 60-74 tahun dengan rerata usia 70,13 tahun, perempuan (71%), durasi pendidikan ≥12 tahun (90%). Terdapat 18 (18% subjek) lansia yang mengalami frailty. Analisis bivariat menunjukkan bahwa faktor yang memiliki hubungan signifikan adalah usia (p: <0,001; RO: 7,633; 95%CI: 2,519 – 23,127) dan constructional praxis (p: 0,037; RO: 3,162; 95%CI: 1,032 – 9,685). Simpulan: Frailty memiliki hubungan bermakna dengan usia dan fungsi kognitif constructional praxis. Dengan usia menjadi faktor yang paling memengaruhi dan meningkatkan risiko frailty pada lansia.
Adaptasi Kultural dan Data Normatif Pemeriksaan Olfaktori pada Populasi Lansia Indonesia Martin, Juvenius; Chandra, Kenly; Vebriana, Gennesia; Putra, Aditya; Kristian, Kevin; Handajani, Yvonne Suzy; Turana, Yuda
Oto Rhino Laryngologica Indonesiana Vol. 55 No. 2 (2025): VOLUME 55, NO. 2 JULY - DECEMBER 2025
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v55i2.736

Abstract

Background: The olfactory sense plays a vital role in well-being and cognitive health, particularly in the older adults. Olfactory dysfunction is linked to neurodegenerative diseases, and geriatric syndromes like frailty. Existing cognitive tests are education-biased, limiting their applicability. Cultural adaptation of olfactory tests enhances diagnostic accuracy, necessitating region-specific normative data for Indonesia. Purpose: To establish normative olfactory scores for Indonesia’s older adult population using a culturally adapted odor identification test. Method: A descriptive study was conducted on 205 healthy participants aged 60 and above, in Jakarta. Eight culturally familiar odors were used in a forced-choice identification test. Normative data were generated based on percentiles, with the 10th percentile serving as the cut off for hyposmia. Data were analyzed using Statistical Package for the Social Sciences (SPSS). Result: Olfactory function was found to decline with age. Hyposmia thresholds were determined: individuals aged 60-64 years were considered hyposmic if they identified fewer than five odors, while those aged 80+ were hyposmic if they identified fewer than two odors. No significant differences were found between education levels, as both groups shared the same hyposmia thresholds. Conclusion: The study provided normative olfactory data specific to the Indonesia’s older adult population. These results supported the use of culturally adapted tests in clinical practice to detect olfactory dysfunction, which might indicate early cognitive decline. Further research should include longitudinal studies to capture changes over time.
Association of Cognitive Function, Depression, and Social Engagement with Quality of Life among Community-Dwelling Elderly in West Jakarta, Indonesia Wijaya, Kenneth Noah; Suryakusuma, Linda; Handajani, Yvonne Suzy; Turana, Yuda
Althea Medical Journal Vol 12, No 4 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n4.4214

Abstract

Background: As Indonesia’s elderly population grows, quality of life (QoL) has become a critical indicator of healthy aging. Evidence regarding the influence of cognitive function, depression, and social engagement on QoL remains inconsistent and is often limited to institutionalized elderly. This study examined these associations among community-dwelling elderly in an urban setting.Methods: A cross-sectional study was conducted at PUSAKA Kebon Jeruk, West Jakarta, from March to November 2023. Ninety-eight participants aged ≥60 years were selected using simple random sampling. Cognitive function was assessed using the Montreal Cognitive Assessment–Indonesian version (MoCA-INA), depression using the Geriatric Depression Scale (GDS), social engagement using the Social Disengagement Index, and QoL using the WHO Quality of Life–Brief Version (WHOQOL-BREF). Data were analyzed using Chi-square, Fisher’s exact, and multivariate logistic regression.Results: Most respondents were female (71.4%), aged 60–74 years (74.5%). The majority demonstrated normal cognitive function (63.3%), good social engagement (90.8%), and no depression. Overall QoL satisfaction was high, particularly in the social relationship (71.4%) and environmental domains (90.8%). Bivariate analysis showed associations between education, cognitive function, social engagement, gender, depression and specific QoL domains (p<0.05). Multivariate analysis identified gender as the strongest predictor of the environmental QoL (OR=5.63, p=0.025), education for social relationship (OR=2.99, p=0.020), and depression for general health perception (OR=3.16, p=0.041).Conclusions: Cognitive function, depression, education, and social engagement are key determinants of QoL among community-dwelling elderly. Community-based interventions focusing on mental health, cognitive stimulation, and social participation may improve QoL and support healthy aging. 
HUBUNGAN PARAMETER KEBUGARAN FISIK DENGAN SINDROMA FRAILTY PADA LANSIA DI JAKARTA Hariyanto, Rayner Abdiwijaya; Suryakusuma, Linda; Handajani, Yvonne Suzy; Turana, Yuda
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 42 No 2 (2026): Volume 42, No 2 - Maret 2026 (in Press)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Frailty is a multifactorial geriatric syndrome resulting from the loss of the body's ability to cope with stressors due to aging. According to a study conducted by Asenso et al., the global prevalence of frailty is 13.6%. Aim: This study is aimed to understand the relationship between physical fitness parameters and frailty syndrome in the elderly. Methods: This study uses a cross-sectional involving 98 respondents aged 60 years and above. ADL was measured using the Barthel Index. Balance was measured using the Berg Balance Scale. Physical activity was measured using the SQUASH questionnaire with cutoffs based on the GPAQ. Frailty status was assessed using the Fried frailty phenotype. Results: From 98 respondents, the majority were female (71.4%), aged 60-74 years (74.5%), with a higher education level (51%). A total of 18.4% of the elderly experienced frailty. Chi-square analysis showed that significant factors were age (p<0.001; OR: 7.408), ADL (p=0.019; OR: 3.944), Balance (p=0.042; OR: 7,800), and physical activity (p=0.014; OR: 3.714). Multiple logistic regression showed that age is the most influential factor in frailty (p=0.002; OR: 6,209) and followed by physical activity (p=0.030; OR: 3.834). Discussion: Age, ADL, balance, and physical activity were found to have a significant relationship with frailty. Among these factors, age was identified as the most influencing factor. Keywords: ADL, age, balance, elderly, frailty, physical activity
Co-Authors Aditya Putra, Aditya Barus, Jimmy Fransisco Abadinta Budhy, Carissa Marvella Budiharsana, Meiwita Paulina Chandra, Kenly Christy, Kezia David Reinaldo Sebastian Gunawan Elsiandi, Caroline Alvina Felicia, Tesya Giovanny, Audrey Carissa Gunawan, David Reinaldo Sebastian Halim, Magdalena Surjaningsih Hardi, Nicholas Hariyanto, Rayner Abdiwijaya Ika Suswanti Kezia Christy Konny, Lisye kridawati, atik Kristian, Kevin Kwok, Lyvia Ariella Latasya, Chelsea Destania Lim, Sebastian Lusia Gani Maria Anggi Sylvani Martin, Juvenius Nelly Tina Widjaja Pakpahan, Hotmaria Agustina Piustan, Mas Eaufrat Prasetya, Virginia Geraldine Hanny Pricilya H. Wangi Rahardjo, Tri Budi sandy Ayu Monica Silalahi Sani, Tara Puspitarini Schröder-Butterfill, Elisabeth Sejati, Fabian Suryakusuma, Linda Suwito, Michelle Margaretha Tanumihardja, Tommy Tanuwijaya, Melyana Thiantoro, Benedicta Ann Clarabelle Vebriana, Gennesia Vinsalia, Thania Wijaya, Kenneth Noah Yuda Turana