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Correlation between NLR and PLR with the Severity of COVID-19 Inpatients Fitriana Andiani; Rita Herawati; Yani Triyani
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 29, No 1 (2022)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v29i1.1924

Abstract

When the COVID-19 outbreak is ongoing, the classification of COVID-19 patients based on the severity assessment is necessary to optimize the allocation of existing resources and early management interventions to improve prognosis. Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) are two of the most common, simple, inexpensive, rapid, and widely available tests in all health facilities, which indirectly indicate the inflammatory status of COVID-19 patients. This study aimed to analyze the correlation between NLR and PLR with the severity of COVID-19 inpatients. This cross-sectional study was conducted retrospectively using medical record data of COVID-19 patients hospitalized at Al Islam Hospital, Bandung, from January to March 2021. COVID-19 patients involved in this study were classified into moderate, severe, and critical degrees. Statistical analysis was carried out using ANOVA or Kruskal-Wallis and Spearman with a significant value of p < 0.05. The median NLR and PLR results based on the severity were 3.49; 6.27; 8.4 (p<0.001) and 159.2; 202.6; 250.9 (p<0001), respectively. There was a correlation between NLR and PLR and the severity with r= 0.415 (p<0.001) and r=0.216 (p<0.001), respectively. The correlation between NLR and the severity was stronger than PLR. Therefore, it was concluded that there was a correlation between NLR and PLR with the severity of COVID-19 patients.
Kejadian Hiperglikemia Baru Akibat Infeksi Covid-19 Lukman Hakim Muttaqien; Yani Triyani; Wida Purbaningsih
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.5564

Abstract

Abstract. Coronavirus disease (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. The SARS-CoV-2 virus has a spike-like protein (S) structure, which will bind to the angiotensin converting enzyme 2 (ACE2) receptor. The number of tissues that express ACE2 receptors causes varied symptoms, ranging from mild symptoms such as coughing, to severe symptoms such as digestive disorders, heart failure, hypertension, and other systemic disorders such as hyperglycemia. So that there are many cases of increased blood sugar levels in COVID-19 patients which cause hyperglycemia. This study aims to determine the relationship between the incidence of new hyperglycemia and COVID-19. This study was conducted by taking medical record data at Al-Islam Hospital in the January-September 2021 period to obtain data on COVID-19 hospitalized patients and data on current blood sugar. This study used an analytical observational method with a case control design and the sampling technique was carried out using the total sampling method and analysis using the chi-square test. The medical record samples studied were 171 medical records at Al-Islam Bandung Hospital. The results showed that most of the subjects experienced hyperglycemia as many as 44 people (51.8%), and there was a significant relationship between COVID-19 infection and the incidence of hyperglycemia (P=0.038). COVID-19 infection is one of the causes of hyperglycemia. Abstrak. Penyakit Coronavirus (COVID-19) adalah penyakit infeksius yang disebabkan oleh virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Virus SARS-CoV-2 memiliki struktur protein seperti spike protein (S), yang akan berikatan dengan reseptor angiotensin converting enzyme 2 (ACE2). Banyaknya jaringan yang mengekspresikan reseptor ACE2 menimbulkan gejala yang bervariasi, berawal dari gejala ringan seperti batuk, hingga gejala berat seperti gangguan pencernaan, gagal jantung, hipertensi, dan gangguan sistemik lain seperti hiperglikemia. Sehingga banyak kasus kenaikan kadar gula darah pada pasien COVID-19 yang menyebabkan hiperglikemia. Penelitian ini bertujuan untuk mengetahui hubungan antara kejadian hiperglikemia baru dengan COVID-19. Penelitian ini dilakukan dengan mengambil data rekam medis di RS Al-Islam pada periode Januari–September 2021 untuk mendapatkan data pasien rawat inap COVID-19 dan data gula darah sewaktu. Penelitian ini menggunakan metode observasional analitik dengan rancangan kasus control dan Teknik pengambilan sample dilakukan dengan metode total sampling serta analisis menggunakan uji chi-square. Sampel rekam medis yang diteliti sebanyak 171 rekam medis di RS Al-Islam Bandung. Hasil penelitian didapatkan Sebagian besar subjek mengalami hiperglikemia sebanyak 44 orang (51,8%), dan terdapat hubungan yang signifikan antara infeksi COVID-19 dengan kejadian hiperglikemia (P=0,038). Infeksi COVID-19 menjadi salah satu penyebab hiperglikemia.
Diabetes Melitus sebagai Komorbiditas Utama terhadap Mortalitas Pasien COVID-19 Zahra Salsabila; Yani Triyani; Sadiah Achmad
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6721

Abstract

Abstract. Cases of COVID-19 are rapidly increasing and spreading throughout Indonesia and have an impact on the degree of severity and the number of deaths in the population that are affected by the presence of comorbidities. The purpose of this study was to analyze the relationship between comorbidities and mortality in COVID-19 patients. This study uses analytic methods with a cross-sectional research design. Data were obtained from the medical records of inpatients with confirmed COVID-19 at Al-Islam Hospital Bandung for the 2021 period. The statistical test used a univariate data test by looking at the characteristics of COVID-19 patients based on age, sex, and length of stay and using the Chi test -Square to analyze whether there is a relationship between the independent and dependent variables. The number of respondents in this study was 2,047 people, with the most age being ≥60 years (39.5%), male sex (51.3%), with the highest comorbidity diabetes mellitus (41.9%), followed by hypertension (35.7%) and renal disease (12.4%) which have CFR values of 10.1%, 5.9%, and 5.2% respectively. Patients with comorbid diseases have a decreased immune response and the location of ACE-2 receptors is found not only in the respiratory tract but also in other organs such as the pancreas and kidneys. The conclusion shows that there is a relationship between comorbidities and mortality of COVID-19 patients at Al-Islam Hospital Bandung in 2021 with a p-value <0.001 (p <0.05) Abstrak. Kasus COVID-19 dengan cepat meningkat dan menyebar ke seluruh Indonesia serta berdampak pada derajat keparahan dan jumlah kematian populasi yang dipengaruhi oleh adanya komorbiditas. Tujuan penelitian ini adalah menganalisis hubungan komorbiditas dengan mortalitas pasien COVID-19. Penelitian ini menggunakan metode analitik dengan rancangan penelitian cross sectional. Data diperoleh dari rekam medis pasien rawat inap yang terkonfirmasi COVID-19 di Rumah Sakit Al-Islam Bandung Periode 2021. Uji Statistik menggunakan uji data univariat dengan melihat karakteristik pasien COVID-19 berdasarkan usia, jenis kelamin, dan lama rawat inap serta menggunakan uji Chi-Square untuk menganalisis ada tidaknya hubungan antara variable bebas dan terikat. Jumlah responden pada penelitian ini sebanyak 2.047 orang, dengan usia yang paling banyak ≥60 tahun (39,5%), jenis kelamin laki-laki (51,3%), dengan komorbiditas tertinggi diabetes melitus (41,9%), disusul dengan hipertensi (35,7%) dan renal disease (12,4%) yang memiliki nilai CFR berturut-turut 10,1%, 5,9%, dan 5,2%. Pasien dengan penyakit komorbid berada dalam penurunan respon imun serta lokasi reseptor ACE-2 yang ditemukan tidak hanya di saluran respirasi, tetapi juga didapatkan di organ lain seperti pankreas dan ginjal. Kesimpulan menunjukkan terdapat hubungan komorbiditas dengan mortalitas pasien COVID-19 di RS Al-Islam Bandung tahun 2021 dengan nilai p <0.001 (p<0.05)
Peran Rasio Trombosit Limfosit dalam Memprediksi Tingkat Keparahan Pasien Covid-19 Tania; Yani Triyani; Rika Nilapsari
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.5963

Abstract

Abstract. COVID-19 is an infectious disease caused by the SARS-CoV-2 group. This disease has been declared by the WHO as a global pandemic. The first case of COVID-19 in Indonesia was reported on March 2, 2020, and the number has continued to increase until now. COVID-19 in Indonesia has spread to various regions, accompanied by increased cases and deaths. The severity of COVID-19 patients is classified into four, namely mild, moderate, severe, and critical, which can be determined by measuring the platelet-lymphocyte ratio value at routine hematological examinations. This RTL has become a new indicator of inflammation to determine the severity of COVID-19. Based on this phenomenon, the problem in this research is formulated as follows: (1) Is there a relationship between the platelet-lymphocyte ratio in moderate cases of COVID-19 at Al-Islam Hospital in Bandung? (2) Is there a relationship between the platelet-lymphocyte ratio in severe cases of COVID-19 at Al-Islam Hospital in Bandung? (3) Does the platelet-lymphocyte ratio act as an indicator of the severity of COVID-19 patients at Al-Islam Hospital Bandung? (4) What is the cut-off value of the platelet-lymphocyte ratio as an indicator of severity in COVID-19 patients at Al-Islam Hospital in Bandung?. The research design uses a diagnostic test method with a cross-sectional approach with data analysis techniques using Chi-square. The population selected in this study were confirmed COVID-19 patients based on RT-PCR results, which were treated at Bandung Al-Islam Hospital. Using the sampling technique, Total Sampling, the number of research samples was 350 patients. The data collection technique used in this study was from medical records. The data analysis technique used in this research is the descriptive analysis technique. The results of this study are: There is a relationship between the platelet-lymphocyte ratio (p-value=0.009) and the severity of COVID-19 patients at Al-Islam Hospital Bandung. Abstrak. COVID-19 merupakan penyakit menular yang disebabkan oleh kelompok SARS-CoV-2. Penyakit ini telah ditetapkan oleh WHO sebagai pandemi global. Kasus pertama COVID-19 di Indonesia dilaporkan pada tanggal 2 Maret 2020, dan jumlahnya terus meningkat hingga sekarang. Penyebaran COVID-19 di Indonesia menyebar ke berbagai wilayah dengan diiringi peningkatan jumlah kasus dan kematian. Derajat keparahan pasien COVID-19 diklasifikasikan menjadi empat yaitu derajat ringan, sedang, berat dan kritis yang dapat ditentukan dengan mengukur nilai rasio trombosit limfosit pada pemeriksaan hematologi rutin. RTL ini ini telah menjadi salah satu indikator peradangan yang baru untuk menentukan derajat keparahan COVID-19. Berdasarkan hal tersebut, maka permasalahan dalam penelitian ini dirumuskan sebagai berikut: (1) Apakah terdapat hubungan antara rasio trombosit limfosit pada kasus COVID-19 derajat sedang di RS Al-Islam Bandung? (2) Apakah terdapat hubungan antara rasio trombosit limfosit pada kasus COVID-19 derajat berat di RS Al-Islam Bandung? (3) Apakah rasio trombosit limfosit berperan sebagai indikator derajat keparahan pasien COVID-19 di RS Al-Islam Bandung? (4) Berapakah nilai cut off rasio trombosit limfosit sebagai indikator derajat keparahan pada pasien COVID-19 di RS Al-Islam Bandung?. Desain penelitian ini menggunakan metode uji diagnostik dengan pendekatan cross sectional dengan teknik analisis data menggunakan Chi-square. Populasi yang dipilih dalam penelitian ini adalah pasien terkonfirmasi COVID-19 berdasarkan hasil RT-PCR yang di rawat di Rumah Sakit Al-Islam Bandung. Dengan teknik pengambilan sampel yaitu Total Sampling diperoleh jumlah sampel penelitian sebanyak 350 pasien. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah dari rekam medik. Adapun teknik analisis data yang digunakan dalam penelitian ini adalah teknik analisis deskriptif. Hasil penelitian ini adalah: Terdapat hubungan antara rasio trombosit limfosit (p-value=0,009) dengan derajat keparahan pasien COVID-19 di Rumah Sakit Al-Islam Bandung.
Pengaruh Gambaran Radiografi Thoraks dan Trombosit dengan Keparahan Pasien Covid-19 Fauzan Rahman Latama; Sadeli Masria; Yani Triyani
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6443

Abstract

Abstract. Coronavirus Disease 2019 (COVID-19) is a disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). There is some way to diagnose Covid-19 patient, one of which is thrombocyte and imaging of Chest X-ray. The purpose of this study is to determine the relationship between thrombocyte value and imaging of Chest x-ray in severity of Covid-19 patients. This research uses total sampling method. The subject of this study was medical records of patients diagnosed Covid-19 who were hospitalized at Al-Islam Hospiital Bandung for the time period between January-March 2021. Data analysis used the chi square test. The result of this study showed that thrombocyte value has no significant relationship with severity in Covid-19 patients (p-value = 0.392) and Chest x-ray imaging has significant relationship with severity in Covid-19 Patients (p-value = 0.0001.). This study concluded that thrombocyte value has no significant relationshop with severity in Covid-19 patients and chest x-ray imaging has significant relationship with severity in Covid-19 patients. Abstrak. Coronavirus disease 2019 (Covid-19) merupakan penyakit infeksi virus yang penyebabnya adalah virus yang bernama severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ada berbagai cara untuk melakukan diagnosis pasien Covid-19, seperti menggunakan jumlah trombosit dan gambaran Radiografi thoraks. Tujuan penelitian ini untuk mengetahui hubungan jumlah trombosit dan gambaran radiografi thoraks dengan tingkat keparahan pada pasien Covid-19. Penelitian ini menggunakan metode total sampling. Subjek penelitian ini adalah rekam medis pasien terkonfirmasi Covid-19 yang dirawat inap di Rumah Sakit Al-Islam Bandung periode Januari-Maret 2021. Analisis data menggunakan uji chi square. Hasil dari penelitian ini menyatakan nilai trombosit dengan tingkat keparahan pasien Covid-19 tidak memiliki hubungan (p-value = 0.392) dan menyatakan gambaran chest x-ray dengan tingkat keparahan pasien Covid-19 memiliki hubungan (p-value = 0.0001). kesimpulan dari penelitian ini adalah nilai trombosit dan tingkat keparahan pasien Covid-19 tidak memiliki hubungan dan gambaran radiografi toraks memiliki hubungan dengan tingkat keparahan pasien Covid-19.
Perbandingan Cure Rate Obat-obat Antiskabies di Formularium Nasional dengan Non-Formularium Nasional Rizki Amalia Nashuha; Satryo Waspodo; Yani Triyani
Cermin Dunia Kedokteran Vol 48 No 12 (2021): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i12.173

Abstract

Skabies adalah penyakit kulit yang disebabkan oleh tungau Sarcoptes scabiei var hominis. Di Indonesia, skabies menduduki urutan ketiga dari 12 penyakit kulit tersering. Di antara sebelas faktor yang bisa memengaruhi prevalensi skabies di komunitas, salah satunya adalah kegagalan pengobatan. Penelitian ini bertujuan untuk mengetahui perbandingan cure rate obat-obat antiskabies di Formularium Nasional, yaitu permethrin dan salep 2–4, dengan Non-Formularium Nasional seperti benzyl benzoate, ivermectin, gamma benzene hexachloride, crotamiton, dan Tinospora cordifolia. Metode penelitian ini adalah scoping review dari September 2020–Desember 2020. Pencarian sistematis melalui database elektronik PubMed, Science Direct, Springer Link, Google Scholar, dan Cochrane sesuai kriteria inklusi dan eksklusi; skrining menggunakan kriteria PICOS (Patient, Intervention, Comparison, Outcome, dan Study). Hasil pencarian adalah 15 artikel; 11 artikel menunjukkan bahwa permethrin memiliki cure rate lebih tinggi daripada benzyl benzoate, ivermectin, gamma benzene hexachloride, dan crotamiton. Dua artikel menunjukkan ivermectin memiliki cure rate lebih tinggi daripada lindane dan sulfur. Satu artikel menunjukkan terapi kombinasi sulfur lebih baik daripada terapi tunggal. Satu artikel menunjukkan bahwa Tinospora cordifolia memiliki cure rate yang tinggi. Disimpulkan bahwa permethrin sebagai salah satu obat antiskabies yang terdapat di Formularium Nasional, memiliki cure rate lebih tinggi daripada obat-obat antiskabies Non-Formularium Nasional. Scabies is the third most common skin disease in Indonesia; it is caused by Sarcoptes scabiei var hominis mite. This study aims to compare the cure rate of antiscabietic drugs in the National Formulary, namely permethrin and 2–4 ointment with the Non-National Formularies such as benzyl benzoate, ivermectin, gamma benzene hexachloride, crotamiton, and Tinospora cordifolia. The systematic search was done in September 2020–December 2020 from electronic databases i.e. PubMed, Science Direct, Springerlink, Google Scholar, and Cochrane; using the inclusion and exclusion criteria and PICOS (Patient, Intervention, Comparison, Outcome, and Study) criteria, The search resulted in 15 articles; 11 articles show that permethrin has better cure rate than benzyl benzoate, ivermectin, gamma benzene hexachloride, and crotamiton. Two articles show that Ivermectin has higher cure rate than lindane and sulfur. One article suggests sulfur combination therapy is preferable to single therapy. One article shows that Tinospora cordifolia has a high cure rate. The conclusion is that permethrin as one of antiscabietic drug in National Formulary has higher cure rate than Non-National Formulary antiscabietic drugs.
PEMBERDAYAAN TOKOH MASYARAKAT DALAM PENDAMPINGAN PENCEGAHAN PENYAKIT REUMATIK DEGENERATIF DI KAMPUNG PERENG DESA PANGAUBAN KECAMATAN PACET KABUPATEN BANDUNG Muhammad Iqbal; Dede Setiapriagung; Nuri Amalia; Yani Triyani
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 7, No 1 (2023): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v7i1.13166

Abstract

ABSTRAKHasil survey masyarakat di kampung Pereng, Desa Pangauban Kecamatan Pacet Kabupaten  Bandung sekitar 70% terdiri dari orang tua yang sering mengeluhkan penyakit degeneratif terutama reumatik, namun jarang berobat ke puskesmas. Kegiatan pengabdian di daerah tersebut bertujuan memberikan solusi permasalahan dengan pendampingan tokoh masyarakat untuk mengenal cara hidup sehat islami sebagai salah satu pencegahan penyakit yang sering dikeluhkan warga. Metode yang dilakukan pada tahapan awal adalah penjaringan kesehatan warga untuk mengetahui jenis penyakit yang paling banyak ditemukan. Tahapan selanjutnya adalah melakukan pendampingan berupa dialog interaktif kepada para tokoh masyarakat sebagai corong kesehatan masyarakat, dan dilakukan pre dan post test untuk menilai pengetahuan tentang penyakit degeneratif. Kegiatan dilakukan di mesjid kampung Pereng, bulan Agustus–Oktober 2022. Hasil penjaringan kepada 135 orang, ditemukan warga berusia >61 tahun sebanyak 106 warga (79%), dan penyakit terbanyak yang ditemukan adalah jaringan otot dan sendi 32 orang (24%), kedua kasus hipertensi 24 orang (18%), hal ini sangat berhubungan dengan gaya dan pola hidup yang masih belum baik. Sebagai kesimpulan pendampingan yang dilakukan dapat menambah pengetahuan tentang pencegahan penyakit degeneratif kepada para tokoh masyarakat, yang terlihat dari adanya peningkatan skor pengisian post test setelah pendampingan dibandingkan pre test. Kata kunci: pemberdayaan; pencegahan penyakit degenerative; tokoh masyarakat. ABSTRACTThe results of a community survey in Pereng, Pangauban Village, Pacet District, Bandung Regency, around 70% consisted of parents who often complained of degenerative diseases, especially rheumatism, but rarely went to the puskesmas. Community service aim to provide solutions to problems by assisting community leaders to know the healthy Islamic way of life as one of the preventions of diseases often complained. The method used in the early stages was a citizen health screening to find the diseases most commonly found. The next stage is to assist community leaders as public health mouthpieces, according by interactive dialogue and to fill in the pre and post-tests to assess knowledge about degenerative diseases. The activity was carried out at the Pereng village mosque, August–October 2022.The screening results found 135 residents, 106 residents aged >61 years (79%), and most of the diseases found were muscle and joint tissue (rheumatism) in 32 people (24%), this is very related to lifestyle and lifestyle which is still not good. In conclusion, the assistance provided can increase knowledge about preventing degenerative diseases to community leaders, which can be seen from the increase in post-test filling scores after mentoring compared to the pre-test. Keywords: community leaders; empowerment; prevention of degenerative diseases
Correlation between NLR and PLR with the Severity of COVID-19 Inpatients Fitriana Andiani; Rita Herawati; Yani Triyani
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 29 No. 1 (2022)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v29i1.1924

Abstract

When the COVID-19 outbreak is ongoing, the classification of COVID-19 patients based on the severity assessment is necessary to optimize the allocation of existing resources and early management interventions to improve prognosis. Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) are two of the most common, simple, inexpensive, rapid, and widely available tests in all health facilities, which indirectly indicate the inflammatory status of COVID-19 patients. This study aimed to analyze the correlation between NLR and PLR with the severity of COVID-19 inpatients. This cross-sectional study was conducted retrospectively using medical record data of COVID-19 patients hospitalized at Al Islam Hospital, Bandung, from January to March 2021. COVID-19 patients involved in this study were classified into moderate, severe, and critical degrees. Statistical analysis was carried out using ANOVA or Kruskal-Wallis and Spearman with a significant value of p < 0.05. The median NLR and PLR results based on the severity were 3.49; 6.27; 8.4 (p<0.001) and 159.2; 202.6; 250.9 (p<0001), respectively. There was a correlation between NLR and PLR and the severity with r= 0.415 (p<0.001) and r=0.216 (p<0.001), respectively. The correlation between NLR and the severity was stronger than PLR. Therefore, it was concluded that there was a correlation between NLR and PLR with the severity of COVID-19 patients.
Diabetes Melitus sebagai Komorbiditas Utama terhadap Mortalitas Pasien COVID-19 Zahra Salsabila; Yani Triyani; Sadiah Achmad
Jurnal Riset Kedokteran Volume 3, No.2, Desember 2023, Jurnal Riset Kedokteran (JRK)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrk.v3i2.3000

Abstract

Abstract. The purpose of this study was to analyze the relationship between comorbidities and mortality in COVID-19 patients. This study uses analytic methods with a cross-sectional research design. Data were obtained from the medical records of inpatients with confirmed COVID-19 at Al-Islam Hospital Bandung for the 2021 period. The statistical test used a univariate data test by looking at the characteristics of COVID-19 patients based on age, sex, and length of stay and using the Chi test -Square to analyze whether there is a relationship between the independent and dependent variables. The number of respondents in this study was 2,047 people, with the most age being ≥60 years (39.5%), male sex (51.3%), with the highest comorbidity diabetes mellitus (41.9%), followed by hypertension (35.7%) and renal disease (12.4%) which have CFR values of 10.1%, 5.9%, and 5.2% respectively. Patients with comorbid diseases have a decreased immune response and the location of ACE-2 receptors is found not only in the respiratory tract but also in other organs such as the pancreas and kidneys. The conclusion shows that there is a relationship between comorbidities and mortality of COVID-19 patients at Al-Islam Hospital Bandung in 2021 with a p-value <0.001 (p <0.05). Abstrak. Tujuan penelitian ini adalah menganalisis hubungan komorbiditas dengan mortalitas pasien COVID-19. Penelitian ini menggunakan metode analitik dengan rancangan penelitian cross sectional. Data diperoleh dari rekam medis pasien rawat inap yang terkonfirmasi COVID-19 di Rumah Sakit Al-Islam Bandung Periode 2021. Uji Statistik menggunakan uji data univariat dengan melihat karakteristik pasien COVID-19 berdasarkan usia, jenis kelamin, dan lama rawat inap serta menggunakan uji Chi-Square untuk menganalisis ada tidaknya hubungan antara variable bebas dan terikat. Jumlah responden pada penelitian ini sebanyak 2.047 orang, dengan usia yang paling banyak  ≥60 tahun (39,5%), jenis kelamin laki-laki (51,3%), dengan komorbiditas tertinggi diabetes melitus (41,9%), disusul dengan hipertensi (35,7%) dan renal disease (12,4%) yang memiliki nilai CFR berturut-turut 10,1%, 5,9%, dan 5,2%. Pasien dengan penyakit komorbid berada dalam penurunan respon imun serta lokasi reseptor ACE-2 yang ditemukan tidak hanya di saluran respirasi, tetapi juga didapatkan di organ lain seperti pankreas dan ginjal. Kesimpulan menunjukkan terdapat hubungan komorbiditas dengan mortalitas pasien COVID-19 di RS Al-Islam Bandung tahun 2021 dengan nilai p <0.001 (p<0.05).
Tingkat Pengetahuan Talasemia Pada Mahasiswa Fakultas Kedokteran Universitas Islam Bandung Intan Purnamasari; Yani Triyani; Sara Puspita
Jurnal Riset Kedokteran Volume 4, No.1, Juli 2024, Jurnal Riset Kedokteran (JRK)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrk.v4i1.3755

Abstract

Abstract. Thalassemia is a congenital blood disorder caused by failure to form hemoglobin which damages red blood cells and results in anemia or lack of blood in sufferers. As the number of thalassemia sufferers increases, awareness of the importance of knowledge of thalassemia must be raised among the public, especially among students at the Faculty of Medicine, Bandung Islamic University as medical personnel in the future must be able to educate the public well. This research aims to determine the level of knowledge of students at the Faculty of Medicine, Islamic University of Bandung about thalassemia. The research subjects were 204 people. This research uses an analytical observational method with a cross-sectional approach. The results of this research show that the majority of students at the Faculty of Medicine, Bandung Islamic University for the 2022/2023 academic year have a good level of knowledge regarding thalassemia (85.3%). A good level of knowledge among students, especially students at the Faculty of Medicine, Bandung Islamic University, is influenced by several things. Students can get information from various sources, starting from formal education and information available on social media. The sources of information obtained by students can increase understanding and knowledge regarding the definition, diagnosis, management and prevention of thalassemia. Abstrak. Talasemia adalah kelainan darah bawaan yang disebabkan oleh kegagalan pembentukan hemoglobin yang merusak sel darah merah dan mengakibatkan anemia atau kekurangan darah pada penderita. Seiring bertambahnya jumlah penderita talasemia, kesadaran akan pentingnya pengetahuan talasemia harus ditumbuhkan di kalangan masyarakat khususnya pada mahasiswa Fakultas Kedokteran Universitas Islam Bandung sebagai tenaga medis di masa yang akan datang sehingga harus mampu mengedukasi masyarakat dengan baik. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan mahasiswa Fakultas Kedokteran Universitas Islam Bandung tentang talasemi. Subjek penelitian sebanyak 204 responden. Penelitian ini menggunakan metode observasional analitik dengan pendekatan potong lintang. Hasil penelitian ini menunjukkan bahwa hasil dari penelitian ini menunjukan bahwa sebagian besar Mahasiswa Fakultas Kedokteran Universitas Islam Bandung tahun akademik 2022/2023 memiliki tingkat pengetahuan yang baik mengenai talasemia (85.3%). Tingkat pengetahuan yang baik pada mahasiswa khususnya pada mahasiswa Fakultas kedokteran Universitas Islam Bandung dipengaruhi oleh beberapa hal. Mahasiswa dapat mendapatkan informasi dari berbagai sumber, mulai dari pendidikan formal maupun informasi yang tersedia di media sosial. Sumber informasi yang didapat oleh mahasiswa dapat meningkatkan pemahaman serta pengetahuan terhadapa pengertian, diagnosis, tatalaksana, serta pencegahan talasemia.
Co-Authors A.A. Ketut Agung Cahyawan W Achmad, Sadiah Alfiyya Nur Mahdiyyah Amalia Salima Apen Afgani Bachti Alisjahbana Budiman , Budiman Clara Juniasari Dadang Rukanta Dede Setiapriagung Dede Setiapriagung Dida Ahmad Gurnida Dr. Rasyidah, S.Ag.,M.ag Dyana Eka Hadiati Eka Hendryanny Eka Hendyanny Eka Hendyanny, Eka Ekowati, RA Retno Elfira Azmi Nabilah Elin Julianti Endang Sutedja Fauzan Rahman Latama Fitriana Andiani Heni Muflihah Herawati, Rita Hikmawati, Deis I. Sjahid Ida Parwati Ilhan Rakha Aryawardana Intan Purnamasari Irma Rahmawati Irma Rahmawati Irna Herliani Irna Herliani, Irna Iskandar, Wedi Ismet Muchtar Nur J. E. Gunawan Julia Hartati Juniartho, Rizky Dwi Lelly Yuniarti Lisa Adhia Garina Lukman Hakim Muttaqien Marlia Singgih Wibowo Maya Tejasari Meike Rachmawati Meta Maulida Damayanti Miranti Kania Dewi Muhammad Iqbal Nadya Aulia Rahmadhanty Nadya Safira Nanan Sekarwana Nashuha, Rizki Amalia Natassja Salsabilla Naufal Fadhillah Alam Naya Valenski Noormartany Nurani Istiqomah Nuri Amalia Nurizzatun Nafsi Nurul Patrisia Nurul Patrisia, Nurul Permana, Benny Permatasari, Ranti Purbaningsih, Purbaningsih Puspita, Sara Raden Anita Indriyanti Rahmawati, Rahmawati Rahmi, Fadhilat Sabila Retno Ekowati Rika Nilapsari Rio Dananjaya Rita Herawati Rizki Amalia Nashuha Rizki Amalia Nashuha Rizki Amalia Nashuha Rizky Dwi Juniartho Sadeli Masria Sadiah Achmad Samsudin Surialaga Sara Puspita Satryo Waspodo Satryo Waspodo Satryo Waspodo Siti Annisa Devi Trusda, Siti Annisa Devi Suryani, Yani Dewi Susan Fitriyana Tania Titah Yudistira Titik Respati Tri Suciati Vidi Permatagalih Vidi Permatagalih, Vidi Waspodo, Satryo Wedi Iskandar Wida Purbaningsih Winni Maharani Zahra Salsabila zahra salsabila Zaki Tashdiq Imani