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All Journal Global Medical and Health Communication SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Abdi Insani Jurnal Integrasi Kesehatan dan Sains Cermin Dunia Kedokteran Bandung Conference Series : Medical Science Bangun Desa : Jurnal Pengabdian Masyarakat Cermin Dunia Kedokteran
Yani Triyani
Bagian Patologi Klinik, Fakultas Kedokteran, Universitas Islam Bandung, Bandung
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Perbandingan Cure Rate Obat-obat Antiskabies di Formularium Nasional dengan Non Formularium Nasional Rizki Amalia Nashuha; Satryo Waspodo; Yani Triyani
Cermin Dunia Kedokteran Vol 48, No 12 (2021): General Medicine
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i12.1581

Abstract

Skabies adalah penyakit kulit yang disebabkan oleh tungau Sarcoptes scabiei var hominis. Di Indonesia, skabies menduduki urutan ketiga dari 12 penyakit kulit tersering. Di antara sebelas faktor yang bisa memengaruhi prevalensi skabies di komunitas, salah satunya adalah kegagalan pengobatan. Penelitian ini bertujuan untuk mengetahui perbandingan cure rate obat-obat antiskabies di Formularium Nasional, yaitu Permethrin dan Salep 2–4 dengan Non Formularium Nasional seperti Benzyl Benzoate, Ivermectin, Gamma Benzene Hexachloride, Crotamiton, dan Tinospora cordifolia. Metode penelitian ini adalah scoping review dari September 2020–Desember 2020. Pencarian sistematis melalui database elektronik PubMed, Science Direct, Springer Link, Google Scholar, dan Cochrane sesuai kriteria inklusi dan eksklusi; skrining menggunakan kriteria PICOS (Pasien, Intervention, Comparison, Outcome, dan Study). Hasil pencarian adalah 15 artikel; 11 artikel menunjukkan bahwa Permethrin memiliki cure rate lebih tinggi daripada Benzyl Benzoate, Ivermectin, Gamma benzene hexachloride dan Crotamiton. Dua artikel menunjukkan Ivermectin memiliki cure rate lebih tinggi daripada Lindane dan Sulfur. Satu artikel menunjukkan terapi kombinasi sulfur lebih baik daripada terapi tunggal. Satu artikel menunjukkan bahwa Tinospora cordifolia memiliki cure rate yang tinggi. Disimpulkan bahwa Permethrin sebagai salah satu obat antiskabies yang terdapat di Formularium Nasional, memiliki cure rate lebih tinggi daripada obat-obat antiskabies Non Formularium NasionalScabies is the third most common skin disease in Indonesia; it is caused by Sarcoptes scabiei var hominis mite. This study aims to compare the cure rate of antiscabietic drugs in the National Formulary, namely Permethrin and 2–4 ointment with the Non-National Formularies such as Benzyl Benzoate, Ivermectin, Gamma Benzene Hexachloride, Crotamiton, and Tinospora cordifolia.. The systematic search was done in September 2020–December 2020 from electronic databases i.e. PubMed, Science Direct, Springerlink, Google Scholar, and Cochrane; using the inclusion and exclusion criteria and PICOS (Patient, Intervention, Comparison, Outcome, and Study) criteria, The search resulted in 15 articles; 11 articles show that Permethrin has better cure rate than Benzyl Benzoate, Ivermectin, Gamma benzene hexachloride and Crotamiton. Two articles show that Ivermectin has higher cure rate than Lindane and Sulfur. One article suggests sulfur combination therapy is preferable to single therapy. One article shows that Tinospora cordifolia has a high cure rate. The conclusion is that Permethrin as one of antiscabietic drug in National Formulary has higher cure rate than Non-National Formulary antiscabietic drugs.
Protective Effect of the T1212C Macrophage Mannose Receptor Gene Polymorphism on Pulmonary Tuberculosis Yani Triyani; Julia Hartati; Budiman Budiman; Ida Parwati; Bachti Alisjahbana
Global Medical & Health Communication (GMHC) Vol 10, No 3 (2022)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v10i3.10706

Abstract

The interaction between the mannose receptor, which is encoded by the macrophage mannose receptor (MMR) gene, and the most virulent antigen (the mannose-capped lipoarabinomannan) cell wall of virulent strains of Mycobacterium tuberculosis trigger an innate and adaptive immune response. It also produces pro and anti-inflammatory cytokines, which play a role in the pathogenesis of tuberculosis (TB) infection. Therefore, MMR gene polymorphism is a risk factor associated with the prognosis for active pulmonary TB. This study aimed to determine the correlation between MMR gene polymorphism and active or latent pulmonary tuberculosis. In this phase, MMR gene polymorphism was analyzed using a case-control design consisting of 74 control group subjects (patients with latent TB) and 74 case groups (patients with active pulmonary TB). The subject’s MMR gene DNA sequencing examination. The study was conducted at the Teaching Hospital, Faculty of Medicine, Universitas Padjadjaran Bandung, from February 2014 to January 2015. The statistical analysis used chi-square and odds ratio. The study’s result has shown the MMR gene polymorphism factor that correlated to the incidence of active pulmonary TB was T1212C (OR=0.253; 95% CI=0.111−0.575; p=0.001). There was an MMR gene in one SNP in the control group (C1323T) only and five single nucleotide polymorphisms (SNPs) in both groups (C1303T, C1221, T1212C, G1186A, and G1195A). Therefore, it can be concluded that MMR gene polymorphism on the T1212C site correlated with the incidence of active pulmonary tuberculosis and was protective.
Diabetes Melitus sebagai Komorbiditas Utama terhadap Mortalitas Pasien COVID-19 Zahra Salsabila; Yani Triyani; Sadiah Achmad
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6721

Abstract

Abstract. Cases of COVID-19 are rapidly increasing and spreading throughout Indonesia and have an impact on the degree of severity and the number of deaths in the population that are affected by the presence of comorbidities. The purpose of this study was to analyze the relationship between comorbidities and mortality in COVID-19 patients. This study uses analytic methods with a cross-sectional research design. Data were obtained from the medical records of inpatients with confirmed COVID-19 at Al-Islam Hospital Bandung for the 2021 period. The statistical test used a univariate data test by looking at the characteristics of COVID-19 patients based on age, sex, and length of stay and using the Chi test -Square to analyze whether there is a relationship between the independent and dependent variables. The number of respondents in this study was 2,047 people, with the most age being ≥60 years (39.5%), male sex (51.3%), with the highest comorbidity diabetes mellitus (41.9%), followed by hypertension (35.7%) and renal disease (12.4%) which have CFR values of 10.1%, 5.9%, and 5.2% respectively. Patients with comorbid diseases have a decreased immune response and the location of ACE-2 receptors is found not only in the respiratory tract but also in other organs such as the pancreas and kidneys. The conclusion shows that there is a relationship between comorbidities and mortality of COVID-19 patients at Al-Islam Hospital Bandung in 2021 with a p-value <0.001 (p <0.05) Abstrak. Kasus COVID-19 dengan cepat meningkat dan menyebar ke seluruh Indonesia serta berdampak pada derajat keparahan dan jumlah kematian populasi yang dipengaruhi oleh adanya komorbiditas. Tujuan penelitian ini adalah menganalisis hubungan komorbiditas dengan mortalitas pasien COVID-19. Penelitian ini menggunakan metode analitik dengan rancangan penelitian cross sectional. Data diperoleh dari rekam medis pasien rawat inap yang terkonfirmasi COVID-19 di Rumah Sakit Al-Islam Bandung Periode 2021. Uji Statistik menggunakan uji data univariat dengan melihat karakteristik pasien COVID-19 berdasarkan usia, jenis kelamin, dan lama rawat inap serta menggunakan uji Chi-Square untuk menganalisis ada tidaknya hubungan antara variable bebas dan terikat. Jumlah responden pada penelitian ini sebanyak 2.047 orang, dengan usia yang paling banyak ≥60 tahun (39,5%), jenis kelamin laki-laki (51,3%), dengan komorbiditas tertinggi diabetes melitus (41,9%), disusul dengan hipertensi (35,7%) dan renal disease (12,4%) yang memiliki nilai CFR berturut-turut 10,1%, 5,9%, dan 5,2%. Pasien dengan penyakit komorbid berada dalam penurunan respon imun serta lokasi reseptor ACE-2 yang ditemukan tidak hanya di saluran respirasi, tetapi juga didapatkan di organ lain seperti pankreas dan ginjal. Kesimpulan menunjukkan terdapat hubungan komorbiditas dengan mortalitas pasien COVID-19 di RS Al-Islam Bandung tahun 2021 dengan nilai p <0.001 (p<0.05)
Pengaruh Gambaran Radiografi Thoraks dan Trombosit dengan Keparahan Pasien Covid-19 Fauzan Rahman Latama; Sadeli Masria; Yani Triyani
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6443

Abstract

Abstract. Coronavirus Disease 2019 (COVID-19) is a disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). There is some way to diagnose Covid-19 patient, one of which is thrombocyte and imaging of Chest X-ray. The purpose of this study is to determine the relationship between thrombocyte value and imaging of Chest x-ray in severity of Covid-19 patients. This research uses total sampling method. The subject of this study was medical records of patients diagnosed Covid-19 who were hospitalized at Al-Islam Hospiital Bandung for the time period between January-March 2021. Data analysis used the chi square test. The result of this study showed that thrombocyte value has no significant relationship with severity in Covid-19 patients (p-value = 0.392) and Chest x-ray imaging has significant relationship with severity in Covid-19 Patients (p-value = 0.0001.). This study concluded that thrombocyte value has no significant relationshop with severity in Covid-19 patients and chest x-ray imaging has significant relationship with severity in Covid-19 patients. Abstrak. Coronavirus disease 2019 (Covid-19) merupakan penyakit infeksi virus yang penyebabnya adalah virus yang bernama severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ada berbagai cara untuk melakukan diagnosis pasien Covid-19, seperti menggunakan jumlah trombosit dan gambaran Radiografi thoraks. Tujuan penelitian ini untuk mengetahui hubungan jumlah trombosit dan gambaran radiografi thoraks dengan tingkat keparahan pada pasien Covid-19. Penelitian ini menggunakan metode total sampling. Subjek penelitian ini adalah rekam medis pasien terkonfirmasi Covid-19 yang dirawat inap di Rumah Sakit Al-Islam Bandung periode Januari-Maret 2021. Analisis data menggunakan uji chi square. Hasil dari penelitian ini menyatakan nilai trombosit dengan tingkat keparahan pasien Covid-19 tidak memiliki hubungan (p-value = 0.392) dan menyatakan gambaran chest x-ray dengan tingkat keparahan pasien Covid-19 memiliki hubungan (p-value = 0.0001). kesimpulan dari penelitian ini adalah nilai trombosit dan tingkat keparahan pasien Covid-19 tidak memiliki hubungan dan gambaran radiografi toraks memiliki hubungan dengan tingkat keparahan pasien Covid-19.
Perbandingan Cure Rate Obat-obat Antiskabies di Formularium Nasional dengan Non-Formularium Nasional Rizki Amalia Nashuha; Satryo Waspodo; Yani Triyani
Cermin Dunia Kedokteran Vol 48 No 12 (2021): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i12.173

Abstract

Skabies adalah penyakit kulit yang disebabkan oleh tungau Sarcoptes scabiei var hominis. Di Indonesia, skabies menduduki urutan ketiga dari 12 penyakit kulit tersering. Di antara sebelas faktor yang bisa memengaruhi prevalensi skabies di komunitas, salah satunya adalah kegagalan pengobatan. Penelitian ini bertujuan untuk mengetahui perbandingan cure rate obat-obat antiskabies di Formularium Nasional, yaitu permethrin dan salep 2–4, dengan Non-Formularium Nasional seperti benzyl benzoate, ivermectin, gamma benzene hexachloride, crotamiton, dan Tinospora cordifolia. Metode penelitian ini adalah scoping review dari September 2020–Desember 2020. Pencarian sistematis melalui database elektronik PubMed, Science Direct, Springer Link, Google Scholar, dan Cochrane sesuai kriteria inklusi dan eksklusi; skrining menggunakan kriteria PICOS (Patient, Intervention, Comparison, Outcome, dan Study). Hasil pencarian adalah 15 artikel; 11 artikel menunjukkan bahwa permethrin memiliki cure rate lebih tinggi daripada benzyl benzoate, ivermectin, gamma benzene hexachloride, dan crotamiton. Dua artikel menunjukkan ivermectin memiliki cure rate lebih tinggi daripada lindane dan sulfur. Satu artikel menunjukkan terapi kombinasi sulfur lebih baik daripada terapi tunggal. Satu artikel menunjukkan bahwa Tinospora cordifolia memiliki cure rate yang tinggi. Disimpulkan bahwa permethrin sebagai salah satu obat antiskabies yang terdapat di Formularium Nasional, memiliki cure rate lebih tinggi daripada obat-obat antiskabies Non-Formularium Nasional. Scabies is the third most common skin disease in Indonesia; it is caused by Sarcoptes scabiei var hominis mite. This study aims to compare the cure rate of antiscabietic drugs in the National Formulary, namely permethrin and 2–4 ointment with the Non-National Formularies such as benzyl benzoate, ivermectin, gamma benzene hexachloride, crotamiton, and Tinospora cordifolia. The systematic search was done in September 2020–December 2020 from electronic databases i.e. PubMed, Science Direct, Springerlink, Google Scholar, and Cochrane; using the inclusion and exclusion criteria and PICOS (Patient, Intervention, Comparison, Outcome, and Study) criteria, The search resulted in 15 articles; 11 articles show that permethrin has better cure rate than benzyl benzoate, ivermectin, gamma benzene hexachloride, and crotamiton. Two articles show that Ivermectin has higher cure rate than lindane and sulfur. One article suggests sulfur combination therapy is preferable to single therapy. One article shows that Tinospora cordifolia has a high cure rate. The conclusion is that permethrin as one of antiscabietic drug in National Formulary has higher cure rate than Non-National Formulary antiscabietic drugs.
PEMBERDAYAAN TOKOH MASYARAKAT DALAM PENDAMPINGAN PENCEGAHAN PENYAKIT REUMATIK DEGENERATIF DI KAMPUNG PERENG DESA PANGAUBAN KECAMATAN PACET KABUPATEN BANDUNG Muhammad Iqbal; Dede Setiapriagung; Nuri Amalia; Yani Triyani
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 7, No 1 (2023): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v7i1.13166

Abstract

ABSTRAKHasil survey masyarakat di kampung Pereng, Desa Pangauban Kecamatan Pacet Kabupaten  Bandung sekitar 70% terdiri dari orang tua yang sering mengeluhkan penyakit degeneratif terutama reumatik, namun jarang berobat ke puskesmas. Kegiatan pengabdian di daerah tersebut bertujuan memberikan solusi permasalahan dengan pendampingan tokoh masyarakat untuk mengenal cara hidup sehat islami sebagai salah satu pencegahan penyakit yang sering dikeluhkan warga. Metode yang dilakukan pada tahapan awal adalah penjaringan kesehatan warga untuk mengetahui jenis penyakit yang paling banyak ditemukan. Tahapan selanjutnya adalah melakukan pendampingan berupa dialog interaktif kepada para tokoh masyarakat sebagai corong kesehatan masyarakat, dan dilakukan pre dan post test untuk menilai pengetahuan tentang penyakit degeneratif. Kegiatan dilakukan di mesjid kampung Pereng, bulan Agustus–Oktober 2022. Hasil penjaringan kepada 135 orang, ditemukan warga berusia >61 tahun sebanyak 106 warga (79%), dan penyakit terbanyak yang ditemukan adalah jaringan otot dan sendi 32 orang (24%), kedua kasus hipertensi 24 orang (18%), hal ini sangat berhubungan dengan gaya dan pola hidup yang masih belum baik. Sebagai kesimpulan pendampingan yang dilakukan dapat menambah pengetahuan tentang pencegahan penyakit degeneratif kepada para tokoh masyarakat, yang terlihat dari adanya peningkatan skor pengisian post test setelah pendampingan dibandingkan pre test. Kata kunci: pemberdayaan; pencegahan penyakit degenerative; tokoh masyarakat. ABSTRACTThe results of a community survey in Pereng, Pangauban Village, Pacet District, Bandung Regency, around 70% consisted of parents who often complained of degenerative diseases, especially rheumatism, but rarely went to the puskesmas. Community service aim to provide solutions to problems by assisting community leaders to know the healthy Islamic way of life as one of the preventions of diseases often complained. The method used in the early stages was a citizen health screening to find the diseases most commonly found. The next stage is to assist community leaders as public health mouthpieces, according by interactive dialogue and to fill in the pre and post-tests to assess knowledge about degenerative diseases. The activity was carried out at the Pereng village mosque, August–October 2022.The screening results found 135 residents, 106 residents aged >61 years (79%), and most of the diseases found were muscle and joint tissue (rheumatism) in 32 people (24%), this is very related to lifestyle and lifestyle which is still not good. In conclusion, the assistance provided can increase knowledge about preventing degenerative diseases to community leaders, which can be seen from the increase in post-test filling scores after mentoring compared to the pre-test. Keywords: community leaders; empowerment; prevention of degenerative diseases
Pendampingan Kader Posyandu pada Pelaksanaan Program Investigasi Kontak Erat Pasien Tuberkulosis Paru di Wilayah Kerja Puskesmas Margahayu Raya Kota Bandung Yani Triyani; Sadiah Achmad; RA Retno Ekowati
Bangun Desa: Jurnal Pengabdian Masyarakat Vol 3, No 1 (2024)
Publisher : Universitas Alma Ata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/jbd.2024.3(1).29-34

Abstract

Berdasarkan hasil survey tahun 2022 cakupan penemuan pasien baru penderita Tuberkulosis (TB) hanya 52,6%. Pengabdian ini bertujuan melakukan pelatihan kader posyandu tentang investigasi kontak erat dan dampak buruk keluarga sebagai penular atau yang tertular TB dapat segera ditangani dengan baik. Metode pelaksanaan PKM ini terdiri dari 3 tahap, ke-1 dengan metode talk show interaktif tentang program kontak erat pasien TB,  dengan sebelum dan sesudah tahap-1 dilakukan pre dan post tes. Tahap ke-2 dilakukan analisis data hasil pre test dan post test. Tahap ke-3 dilakukan pendampingan langsung di lapangan saat pelaksanaan posyandu. Hasil PKM adalah tersosialisasikannya definisi, alur pelaporan dan tindak lanjutnya kontak erat pasien TB  kepada para kader posyandu. Terjadi peningkatan pengetahuan para kader kesehatan tentang investigasi kontak erat yang terlihat  dari peningkatan skor minimun 10 menjadi 60, dan skor maksimun dari 90 menjadi 100 dari nilai pre test dan post test. Berhasil dilakukan penjaringan terhadap 13 anak dan 22 orang dewasa dari 4 pasien baru TB, dan ditemukan 1 orang anak positif dengan tes Mantoux dan 1 orang dewasa yang positif dengan pemeriksaan dahak menggunakan tes cepat molekuler TB. Kesimpulan kegiatan ini akan dapat membantu dalam penemuan dini pasien baru TB sehingga pengobatan bisa lebih cepat dan mencegah penularan lebih lanjut.
Pendampingan kewaspadaan bencana alam longsor dan antisipasinya di Pesantren Sabilunnajat kecamatan Rancah kabupaten Ciamis Raden Anita Indriyanti; Yani Triyani
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 1 (2024): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i1.22259

Abstract

AbstrakBencana alam longsor kabupaten Ciamis pada tahun 2021 mengakibatkan kerusakan asrama putra di pesantren Sabilunnajat. Berdasarkan hasil survey di pesantren Sabilunnajat, belum pernah ada pelatihan kewaspadaan terhadap bencana longsor di pesantren tersebut. Kegiatan pengabdian ini bertujuan memberikan solusi menjadikan kader santri siaga bencana, melalui pelatihan perwakilan santri sebagai kader kesehatan sesuai bimbingan BNPB dengan kolaborasi tim dokter yang tergabung dalam ikatan alumni FK Unisba. Metode yang dilakukan pada tahap awal adalah melakukan edukasi berupa sosialisasi kewaspadaan bencana alam longsor, dan perilaku hidup bersih dan sehat (PHBS) , selanjutnya pembentukan kader santri siaga bencana, serta pembentukan Pos Kesehatan Pesantren berkolaborasi dengan dokter alumni FK Unisba. Kegiatan dilakukan di Pesantren Sabilunnajat-Ciamis, bulan Juni–Agustus 2023. Hasil dari program pengabdian ini adalah didapatkan hasil secara statistik yang meningkat signifikan setelah pemberian penyuluhan, terbentuknya kader pesantren sehat, pembentukan sarana dan prasarana kamar mandi di lokasi aman longsor, berjalannya fasilitasi pelayanan kesehatan gratis melalui kerjasama dengan klinik dikelola oleh alumni Fakultas Kedokteran Unisba. Kata kunci: dokter alumni FK Unisba; kader santri; siaga bencana AbstractThe natural landslide disaster in Ciamis district in 2021 resulted in damage to the boys' dormitory at the Sabilunnajat Islamic boarding school. Based on the results of a survey at the Sabilunnajat Islamic boarding school, there has never been any landslide awareness training at the Islamic boarding school. This service activity aims to provide a solution to make students prepared for disasters through training student representatives as health cadres according to BNPB guidance with the collaboration of a team of doctors who are members of the FK Unisba alumni association. The method used in the initial stage was to provide education in the form of socializing awareness of landslide disasters, and clean and healthy living behavior (PHBS), followed by the formation of santri health cadres, as well as the establishment of Islamic boarding school health posts in collaboration with FK Unisba alumni doctors. Activities were carried out at the Sabilunnajat-Ciamis Islamic boarding school, June–August 2023. The results of this service program were that statistically significant results  increased after providing counseling, the formation of healthy Islamic boarding school cadres, the establishment of bathroom facilities and infrastructure in landslide-safe locations, and ongoing facilitation. free health services in collaboration with clinics managed by alumni of the Unisba Faculty of Medicine. Keywords: FK Unisba alumni doctors, student cadres, disaster preparedness.
Evaluating Risk Factors for Early-onset Neonatal Sepsis Iskandar, Wedi; Juniartho, Rizky Dwi; Triyani, Yani; Permatagalih, Vidi
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13940

Abstract

Neonatal sepsis is a systemic infection that occurs in infants at 28 days of life and is a significant cause of morbidity and death in newborns. Early-onset neonatal sepsis (EONS) occurs within 72 hours after birth and is often associated with infections contracted before or during childbirth. The study aims to evaluate the risk factors of EONS. The study design was a case-control retrospective observational study that evaluated the medical records of neonates who were admitted to the neonatal care unit of Al Islam Hospital Bandung from January 2020 to December 2022. This study assessed the impact of independent variables such as gestational age, birth weight, premature rupture of membrane (PROM), miconeal amniotic fluid, APGAR score of 5 minutes, and the mother's white blood cell count elevation (>15,000/µl). The logistic regression analyses were employed to analyze the data. The logistic regression analyses were employed to analyze the data. The study included 3,103 neonates, of whom 124 met the inclusion criteria. Thirty-nine patients (31.35%) were diagnosed with sepsis, while 85 patients (68.55%) did not have sepsis. Based on bivariate analysis, EONS was significantly linked to low birth weight (p=0.027, 95% CI=0.184 to 0.902, OR=2.455), PROM (p=0.000, 95% CI=4.359 to 26.582, OR=10.764), and the mother's white blood cell count elevation (p=0.002, 95% CI=1.560 to 7.622, OR=3.448). On multivariate analysis, the risk factors were significantly associated (p<0.05), which had an influence of 38.4% on EONS (Nagelkerke R square=0.384). In conclusion, the risk factors for EONS were low birth weight, PROM, and elevation of white blood cell count in the mother, which increased by 38.4% with EONS.
Impact of the COVID-19 Pandemic on Laboratory Services Triyani, Yani; Herawati, Rita; Rahmawati, Rahmawati; Permatasari, Ranti
Global Medical & Health Communication (GMHC) Vol 11, No 3 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i3.12223

Abstract

The positive impact of the coronavirus disease 2019 (COVID-19) pandemic is that hospital laboratory services are excellent when other services are declining. Aside from molecular biology laboratory (polymerase chain reaction, PCR) services for COVID-19 diagnostics, public demand has dramatically increased. It is a retrospective descriptive study that uses data on the total number and types of results of laboratory examination orders that have been verified from the laboratory information system of a hospital from 2018 to 2022. Data analysis is presented in the frequency of the number and type of results of laboratory examination orders and differences in requests for laboratory services before and during the pandemic since the government established it on March 8, 2020. The total number of laboratory requests between January 2018 and December 2022 was 1,943,539 services. The highest increase in laboratory examination services was in molecular biology (98.4%). As the need for community services increases for the PCR severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) examination, which is used in addition to diagnosing confirmed COVID-19 patients, it is also necessary for the community to conduct tracing if a family member has a COVID infection or travel requirements and follow-up for hospital employee exit tests who contracted COVID-19. In conclusion, the COVID-19 pandemic has positively impacted laboratory performance. There have been changes and an increase in the number and types of laboratory examination services and personal performance and management in laboratories.
Co-Authors A.A. Ketut Agung Cahyawan W Alfiyya Nur Mahdiyyah Apen Afgani Bachti Alisjahbana Benny Permana Budiman , Budiman Clara Juniasari Dede Setiapriagung Deis Hikmawati Eka Hendryanny Eka Hendyanny Eka Hendyanny, Eka Elin Julianti Fauzan Rahman Latama Heni Muflihah Herawati, Rita Ida Parwati Irma Rahmawati Irma Rahmawati Irna Herliani Irna Herliani, Irna Iskandar, Wedi Ismet Muchtar Nur Julia Hartati Juniartho, Rizky Dwi Lelly Yuniarti Marlia Singgih Wibowo Maya Tejasari Meike Rachmawati Meta Maulida Damayanti Muhammad Iqbal Nashuha, Rizki Amalia Naufal Fadhillah Alam Noormartany Nurani Istiqomah Nuri Amalia Nurul Patrisia Nurul Patrisia, Nurul Permatasari, Ranti Puspita, Sara Raden Anita Indriyanti Rahmawati, Rahmawati Rahmi, Fadhilat Sabila Retno Ekowati Rika Nilapsari Rizki Amalia Nashuha Rizki Amalia Nashuha Rizki Amalia Nashuha Sadeli Masria Sadiah Achmad Samsudin Surialaga Satryo Waspodo Satryo Waspodo Satryo Waspodo Suryani, Yani Dewi Susan Fitriyana Titah Yudistira Titik Respati Tri Suciati Vidi Permatagalih, Vidi Waspodo, Satryo Wida Purbaningsih Winni Maharani Zahra Salsabila