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All Journal PROSIDING SEMINAR NASIONAL Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) WARTA Syntax Literate: Jurnal Ilmiah Indonesia BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains JKPK (Jurnal Kimia dan Pendidikan Kimia) Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Jurnal Insan Farmasi Indonesia Indonesian Community Journal Abdi Geomedisains Prosiding University Research Colloquium
Dedi Hanwar
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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PAKOM PETERNAK PUYUH DESA GAJAHAN COLOMADU KARANGANYAR Hakim, Lukman; Hanwar, Dedi; Sugiyanto, Eko; Irawati, Zulfa
WARTA WARTA Volume 18, Nomor 2, September 2015
Publisher : Universitas Muhammadiyah Surakarta

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Abstract

The purpose of this activity is improving knowledge and skill of quail farmer’s in waste management of quail. The management of waste is processing of organic fertilizer. The participate in the activity are quail farmer’s in RW II Sub-village Ginung, Gajahan Village, Colomadu, Karanganyar. The result of this activity in step I that is be good attention from a quail farmer’s especiality at trainning time process of product organic fertilizer. As for its result as follows; trainning and assistence quail farmer’s is followed enthusiastic fully by participant and greeted positive by head of Village Gajahan Colomadu, Karanganyar. That are many question in trainning process of product organic fertilizer. The others result in activity is a quail farmer’s started processing of product organic fertilizer in housebreed themselves. The  processing of product organic fertilizer will be clean in Gajahan Village environment and also this activity will be value added toward income quail farmer’s.
PELATIHAN PEMERIKSAAN TAJAM PENGLIHATAN PADA SISWA KELAS 5 SD GEDONGAN I, COLOMADU, KARANGANYAR Sutrisna, Em; Hanwar, Dedi; Indrayudha, Peni; Sujono, Tanti Azizah
WARTA WARTA Volume 10, Nomor 1, Maret 2007
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (24.037 KB) | DOI: 10.23917/warta.v10i1.3210

Abstract

Seeing is crucial aspect in life includes in the field of education. Ifit is not cured the reduction of  sharpness of seeing/visus can affect thestudent ability to study. This action is done to detect  this reduction early.Therefore, the eyes will not be getting worse. The research is done bytraining and demonstrating how to check visus. The location of the researchis SD Gedongan I, Gedongan, Colomadu, Karanganayar. The 31 studentsare checked. The result is that there are 3 students have visus with miop.All the students can participate in this research well.
PAKOM PETERNAK PUYUH DESA GAJAHAN COLOMADU KARANGANYAR Sugiyanto, Eko; Irawati, Zulfa; Hakim, Lukman; Hanwar, Dedi
WARTA WARTA Volume 18, Nomor 2, September 2015
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (62.791 KB) | DOI: 10.23917/warta.v18i2.1958

Abstract

The purpose of this activity is improving knowledge and skill of quail farmer?s in waste management of quail. The management of waste is processing of organic fertilizer. The participate in the activity are quail farmer?s in RW II Sub-village Ginung, Gajahan Village, Colomadu, Karanganyar. The result of this activity in step I that is be good attention from a quail farmer?s especiality at trainning time process of product organic fertilizer. As for its result as follows; trainning and assistence quail farmer?s is followed enthusiastic fully by participant and greeted positive by head of Village Gajahan Colomadu, Karanganyar. That are many question in trainning process of product organic fertilizer. The others result in activity is a quail farmer?s started processing of product organic fertilizer in housebreed themselves. The  processing of product organic fertilizer will be clean in Gajahan Village environment and also this activity will be value added toward income quail farmer?s.
PREDIKSI 3D-MOLEKULAR AKTIVITAS TURUNAN SENYAWA POLIHIDROKSI ZERUMBON TERHADAP GLIKOGEN SINTASE KINASE-3 BETA (GSK-3) MENGGUNAKAN DOCK6 Broto Santoso; Dedi Hanwar; Andi Suhendi
PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2015: Prosiding Bidang MIPA dan Kesehatan The 2nd University Research Colloquium
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Insulin resistance causes 90% of type 2 diabetes mellitus (DM) cases and this is due to an increase in the activity of glycogen synthase kinase-3 (GSK-3). Dephosphorylation and activation of glycogen synthase prevent type 2 diabetes by inhibiting the work of GSK-3 beta isoform primarily. The study was done in unix (mac and linux) operating system with the sequence of steps were optimization of geometry of ligand, ligand and protein preparation, validation of docking methods, molecular docking and analysis, and 3D modeling of ligand-protein interactions. Optimization of target ligand geometry using Gaussian showed that molecular docking score increased 62.5% compared with geometry optimization using MarvinSpace. Polyhydroxy compound zerumbon derivats: ZER04, ZER05 and ZER06 potential to be tested further in the laboratory as an anti- type 2 diabetes both in vitro and in vivo. This is based on the ability of the compounds in term of molecular interactions that better than the native ligand of target protein 4PTE, 4AFJ, 3ZRK, 3GB2, 3DU8 and 1Q3W (60% of the total protein targets tested) as an inhibitor of glycogen synthase kinase- 3 types of beta (GSK-3b).Keywords: polyhydroxyzerumbone, glycogen synthase kinase-3 beta, docking molecular, DOCK6
PELATIHAN PEMERIKSAAN TAJAM PENGLIHATAN PADA SISWA KELAS 5 SD GEDONGAN I, COLOMADU, KARANGANYAR Em Sutrisna; Dedi Hanwar; Peni Indrayudha; Tanti Azizah Sujono
WARTA LPM WARTA Volume 10, Nomor 1, Maret 2007
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/warta.v10i1.3210

Abstract

Seeing is crucial aspect in life includes in the field of education. Ifit is not cured the reduction of  sharpness of seeing/visus can affect thestudent ability to study. This action is done to detect  this reduction early.Therefore, the eyes will not be getting worse. The research is done bytraining and demonstrating how to check visus. The location of the researchis SD Gedongan I, Gedongan, Colomadu, Karanganayar. The 31 studentsare checked. The result is that there are 3 students have visus with miop.All the students can participate in this research well.
PAKOM PETERNAK PUYUH DESA GAJAHAN COLOMADU KARANGANYAR Lukman Hakim; Dedi Hanwar; Eko Sugiyanto; Zulfa Irawati
WARTA LPM WARTA Volume 18, Nomor 2, September 2015
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/warta.v18i2.1958

Abstract

The purpose of this activity is improving knowledge and skill of quail farmer’s in waste management of quail. The management of waste is processing of organic fertilizer. The participate in the activity are quail farmer’s in RW II Sub-village Ginung, Gajahan Village, Colomadu, Karanganyar. The result of this activity in step I that is be good attention from a quail farmer’s especiality at trainning time process of product organic fertilizer. As for its result as follows; trainning and assistence quail farmer’s is followed enthusiastic fully by participant and greeted positive by head of Village Gajahan Colomadu, Karanganyar. That are many question in trainning process of product organic fertilizer. The others result in activity is a quail farmer’s started processing of product organic fertilizer in housebreed themselves. The  processing of product organic fertilizer will be clean in Gajahan Village environment and also this activity will be value added toward income quail farmer’s.
Validation of Atomic Absorption Spectrometry Method for Contamination Determination of Lead (Pb) and Cadmium (Cd) in Methanol Extract and Product of Curcuma xanthorrhiza Roxb. Dedi Hanwar; Devi Eka Nitoviani; Andi Suhendi
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 2, No 3 (2017): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (507.349 KB) | DOI: 10.20961/jkpk.v2i3.11968

Abstract

The validity of atomic absorption spectrometry method for lead (Pb) and cadmium (Cd) determination in methanol extract and product of Curcuma xanthorrhiza was unknown. The aim of this work is to determine the validity of atomic absorption spectrometry method for Pb and Cd determination in methanol extract and product of Curcuma xanthorrhiza. Digestion process was done by wet digestion method and its results were read by atomic absorption spectrometry at a wavelength 217.0 nm for Pb and 228.8 nm for Cd. Validation results found % recovery of Pb and Cd respectively were 87.16% ± 0.38 (RSD 0.42) and 89.10% ± 0.06 (RSD 0.07) in methanol extract of Curcuma xanthorrhiza, 92.62% ± 0.24 (RSD 0.26) and 100.16% ± 0.07 (RSD 0.07) in Curcuma xanthorrhiza product. Precision test found the RSD value for Pb in the methanol extract and product of Curcuma xanthorrhiza were 0.02 and 0.14 respectively, but the RSD value for Cd were not detected. The linearity test results of Pb and Cd standar solution were 0.9998 and 0.9979. The LOD for Pb and Cd were 0.4 ppm and 0.1 ppm, and the LOQ were 1.3 ppm and 0.5 ppm respectively. Based on the % recovery results, the method of Pb and Cd determination by atomic absorption spectrometry is valid for methanol extract and product of Curcuma xanthorrhiza. The levels of Pb in extract and product of Curcuma xanthorrhiza were 2.10 ± 0.001 mg/kg and 4.34 ± 0.001 mg/kg respectively, but the levels of Cd in both samples did not detected.   
Sosialisasi Pemanfaatan Tanaman Obat Keluarga untuk Pencegahan Paparan Covid-19 di Desa Cabeyan, Sukoharjo, Jawa Tengah Luluk Ria Rakhma; Zakky Cholisoh; Setyo Nurwaini; Dedi Hanwar; Erindyah Retno Wikantyasning; Ika Trisharyanti; Rima Munawaroh; Ambar Yunita; Refsya Azanti; Endang Setyaningsih
I-Com: Indonesian Community Journal Vol 2 No 2 (2022): I-Com: Indonesian Community Journal (Agustus 2022)
Publisher : Fakultas Sains Dan Teknologi, Universitas Raden Rahmat Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (442.357 KB) | DOI: 10.33379/icom.v2i2.1468

Abstract

Peningkatan imun tubuh merupakan salah satu himbauan pemerintah untuk pencegahan penyakit semenjak terjadi pandemi virus Covid-19 yang sampai saat ini belum ditemukan obatnya. Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah melakukan sosialisasi pemanfaatan tanaman obat keluarga/empon-empon untuk pencegahan paparan Covid-19 di Desa Cabeyan, Bendosari, Sukoharjo dimana pemahaman warga terkait pencegahan penyakit masih kurang serta belum pernah ada edukasi kepada masyarakat terkait upaya untuk meningkatkan imunitas. Tahapan yang digunakan dalam kegiatan ini antara lain penetapan lokasi sasaran, peninjauan dan observasi lokasi sasaran, perencanaan rancangan dan materi, pengorganisiasian perijinan kegiatan, apersepsi kegiatan, pelaksanaan kegiatan, pelaporan, evaluasi dan tindak lanjut. Penyampaian materi pemanfaatan tanaman obat keluarga menggunakan metode penyuluhan yang meliputi ceramah dan diskusi. Evaluasi menggunakan penilaian kuesioner pre dan post tes yang menunjukkan bahwa terdapat peningkatan pengetahuan pada semua peserta mengenai materi manfaat obat tradisional, pengolahan bahan alam menjadi obat dan penggunaan bahan alam dengan aman.
AKTIVITAS ANTIDIABETES EKSTRAK ETANOL RIMPANG LEMPUYANG EMPRIT (Zingiber amaricans BL) PADA TIKUS PUTIH YANG DIINDUKSI ALOKSAN Kasful Asra Sakika; Dedi Hanwar; Andi Suhendi; Ika Trisharyanti; Broto Santoso
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Perkembangan Terbaru Pemanfaatan Herbal Sebagai Agen Preventif Pada Tera
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.121 KB) | DOI: 10.31942/jiffk.v0i0.1194

Abstract

ABSTRAK Lempuyang di masyarakat dikenal memiliki 3 spesies yaitu lempuyang gajah, wangi, dan emprit. Penelitian sebelumnya menunjukkan lempuyang gajah memiliki aktivitas antidiabetes pada tikus yang diinduksi aloksan. Skrining farmakologi terhadap lempuyang emprit (Zingiber amaricans BL) masih sangat terbatas. Penelitian ini bertujuan untuk mengetahui potensi ekstrak etanol rimpang lempuyang emprit terhadap kadar glukosa darah tikus diabetes yang diinduksi aloksan. Hewan uji yang digunakan adalah 20 ekor tikus jantan putih galur Wistar yang dibagi menjadi 5 kelompok yaitu kelompok kontrol positif menggunakan glibenklamid, kontrol negatif menggunakan akuades, dan 3 kelompok perlakuan ekstrak etanol rimpang lempuyang emprit dengan tingkatan dosis  0,4 g/kg BB, 0,6 g/kg BB dan 0,8 g/kg BB. Pengukuran kadar glukosa darah pada hari ke-0, ke-4 dan ke-19. Data diuji dengan metode analisis statistik menggunakan software SPSS versi 17 for windows. Hasil pengujian menunjukkan bahwa tiga tingkatan dosis ekstrak etanol rimpang lempuyang emprit dan glibenkamid mampu menurunkan kadar glukosa darah dengan bermakna. Kadar rerata glukosa darah pada hari ke-4 untuk masing-masing kelompok dosis 0,4 g/kg BB, 0,6 g/kg BB, 0,8 g/kg BB dan kontrol positif adalah 264,5±18,86 mg/dL, 261,5±30,34 mg/dL, 245,0±29,02 mg/dL dan 264,5±14,30 mg/dL menurun menjadi 105±44,06 mg/dL, 149±45,20 mg/dL, 123,75±21,40 mg/dL dan 112,5±17,75 mg/dL pada hari ke-19. Kata kunci : antidiabetes, tikus jantan, Wistar, Zingiber amaricans.
Validasi Metode KLT-Densitometri untuk Penetapan Kadar Kurkumin pada Produk Obat Herbal Berbasis Curcuma sp. Dedi Hanwar; Siti Aisyah; Andi Suhendi
Prosiding University Research Colloquium Proceeding of The 7th University Research Colloquium 2018: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Kunyit (Curcuma domestica) dan temulawak (Curcuma xanthorrhiza)merupakan tanaman yang banyak digunakan untuk produk obatherbal, yang khasiat utamanya tergantung pada kurkuminoid danminyak atsiri. Dengan adanya perkembangan produk-produk obatbahan alam, maka pengawasan terhadap produk-produk yangberedar di pasaran perlu dilakukan. Tujuan dari penelitian iniadalah untuk mengetahui validasi metode KLT-Densitometri untukpenetapan kadar kurkumin pada produk obat herbal yangmengandung ekstrak kunyit (D1) dan temulawak (D2). Metode KLTDensitometriuntuk analisis kurkumin dilakukan denganmenggunakan fase gerak kloroform: benzena: metanol (80:15:5) danfase diam silika gel GF254. Nilai Rf dari kurkumin yaitu 0,5 yangdideteksi pada λ maksimal 416 nm. Hasil persen perolehan kembaliuntuk parameter akurasi pada sampel berturut-turut yaitu 106,33 ±2,33% (D1) dan 103,14 ± 2,06 (D2). Sedangkan nilai %RSD padapenetapan parameter presisi antara dari sampel D1 dan D2 berturutturutyaitu, 1,39% dan 1,57%, dan pada parameter keterulanganadalah 1,35% dan 1,78%. Sehingga metode KLT-Densitometri validuntuk penetapan kadar kurkumin pada produk herbal.
Co-Authors 'Aina Fahrina Anwar Abidi, Subhan R Amanda Wahyu Kurniawan Ambar Yunita Ambar Yunita Nugraheni Andi Suhendi Andi Suhendi Andi Suhendi Anwar, 'Aina Fahrina Audi Tahta Aurellia Brainandiva Ade Fitria Broto Santoso Cahya Rahma Utami Cheleng, Nisreen Cholisoh, Zakky Desy Nurlela Saanun Devi Eka Nitoviani Eko Sugiyanto Eko Sugiyanto Em Sutrisna Endang Setyaningsih Erindyah Retno Wikantyasning Firdaus, Khisma Arum Handayani, Vivi Resty Heppy Purbasari Ika Trisharyanti Dian Kusumowati Kasful Asra Sakika Khisma Arum Firdaus Khoirunnisa Khoirunnisa Larasati, Arindra Lukman Hakim Lukman Hakim Luluk Ria Rakhma Maharani, Bunga Adhelia Muhammad Ikhsan Al Af Ghani Peni Indrayudha Rahmadhani, Aintan Ramdani, Tasya Eka Refsya Azanti Putri Rima Munawaroh Rosi Hayyu Anjani Saanun, Desy Nurlela Sania Nayasari Khoirunnisa Sari, Aisah Kensar Nawang Wulan Setyo Nurwaini Siti Aisyah Siti Aisyah Subhan R Abidi Tanti Azizah Sujono Vera Widyastuti Vivi Resty Handayani Wahyu Utami, Wahyu Widyastuti, Vera Yuka Aulia Rahma Zulfa Irawati Zulfa Irawati, Zulfa