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Diana Novitasari, Diana
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Effects of vitamin d supplementation on type 2 diabetes mellitus patients Al Aziz, Syaied Auliya; Novitasari, Diana
Science Midwifery Vol 11 No 6 (2024): February: Midwifery and Health Sciences
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i6.1413

Abstract

In Indonesia, around 10.9% of the population has diabetes according to the 2018 basic health research data. It is important for people with diabetes to receive proper treatment to prevent the condition from getting worse. Recently, there have been studies suggesting that taking vitamin D supplements can help improve diabetes. This research aims to explore whether vitamin D supplementation can indeed help control type 2 diabetes mellitus. The approach employed in this investigation entails conducting a comprehensive analysis of existing literature, where relevant articles published in the past 10 years were analyzed based on specific keywords. After finding the appropriate literature, the writing process began. Vitamin D is a substance that acts like a hormone and can increase insulin production in the body. Lot of evidence have shown that taking vitamin D supplements can lower fasting plasma glucose levels, improve insulin resistance, and reduce HbA1c levels when given in high doses over a short period of time. Vitamin D deficiency has also been linked to poor glycemic control in type 2 diabetes mellitus, leading to higher HbA1c levels. Based on the findings from the literature review, it can be concluded that vitamin D supplementation is effective in treating type 2 diabetes mellitus, with a minimum daily dose of 1000 IU. Overall, the evidence suggests that vitamin D supplementation can be a valuable addition to the management of type 2 diabetes mellitus, potentially improving outcomes and overall health in affected individuals. Further research is needed to fully understand the mechanisms behind these benefits and to determine the most effective dosages and treatment protocols.
Hubungan Screen Time Smartphone Dengan Kejadian Obesitas Pada Masyarakat Usia 15-22 Tahun Timotius, Timotius; Novitasari, Diana; Titanic, Pussof Yahyazucah; Chyntia, Chyntia; Ashari, Shoimatul Fitriyah
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.18077

Abstract

Smartphones are no longer necessary in everyday life. Smartphone use has been shown to have a wide-ranging impact on health. Obesity is one of the modern-day health problems that can be exacerbated by excessive smartphone use. The study's goal is to look at the link between smartphone screentime and obesity prevalence. This study's design is a cut width. Data is collected online using Google Forms (G-form). The information gathered included respondents' identities, screen times via smartphone screenshots, and degrees of obesity as indicated by height and weight measurements. There were 135 responses between the ages of 15 and 22. The bulk of respondents (83.7%) utilized cellphones for 6 hours every day. The outcomes of measuring the body mass index revealed that the majority of the respondents (71.11%) were obese. The chi-square test reveals a substantial association between screen time and metabolic health, such as obesity
Hubungan Vitamin D dengan Kontrol Glikemik Menurut HBA1C Pada Pasien Diabetes Mellitus Tipe 1 dan 2 Negara, Tahta Rajesa Bihi Jaya Putra; Novitasari, Diana
Malahayati Nursing Journal Vol 6, No 2 (2024): Volume 6 Nomor 2 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i2.13219

Abstract

ABSTRACT Vitamin D is a fat-soluble secosteroid hormone. It is currently believed that vitamin D has many extraskeletal effects, one of which is related to glucose homeostasis. It has been found that vitamin D deficiency is associated with higher HbA1c levels, increased incidence of DM and decreased glycemic control in DM sufferers. The aim of the current systematic review was to evaluate the effect of vitamin D supplementation on HbA1c. This research is a literature review. A study search was carried out on databases such as PubMed, ScienceDirect, and Google Scholar, and ResearchGate. The included studies were those published within the last 5 years. In a number of studies, it has been observed that serum 25-OH D levels are significantly lower in diabetic patients than in healthy people. It was found that there was an inverse relationship between blood vitamin D levels and HbA1c levels, with low serum vitamin D resulting in greater HbA1c and worse glycemic control. It has also been discovered that low serum vitamin D levels are linked to the development of diabetes complications such DKD and CVD.  High-dose, short-term vitamin D treatment was found to be the most effective for glycemic control. The effectiveness of vitamin D supplementation in glycemic management, however, cannot be established due to inconsistent research findings. Keywords: Vitamin D, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Hba1c  ABSTRAK Vitamin D adalah hormon secosteroid larut kemak yang saat ini diyakini bahwa vitamin D memiliki banyak efek ekstraskeletal, salah satunya adalah terkait homeostasis glukosa. Telah ditemukan bahwa defisiensi vitamin D dikaitkan dengan kadar HbA1c yang lebih tinggi, peningkatan kejadian DM dan penurunan kontrol glikemik pada penderita DM. Tujuan untuk mengevaluasi pengaruh suplementasi vitamin D terhadap HbA1c. Penelitian ini adalah literature review. Pencarian studi dilakukan pada database berupa PubMed, ScienceDirect, dan Google Scholar, dan ResearchGate dengan kata kunci diabetes mellitus, vitamin D, HbA1c, dan glycemic control. Studi-studi yang diinklusikan adalah yang diterbitkan dalam 5 tahun terakhir.   Dalam sejumlah penelitian, telah diamati bahwa kadar serum 25-OH D secara signifikan lebih rendah pada pasien diabetes dibandingkan pada orang sehat.  Kadar HbA1c ditemukan berbanding terbalik dengan kadar vitamin D serum, dimana vitamin D serum yang rendah akan menghasilkan HbA1c yang lebih tinggi, mengartikan bahwa kontrol glikemik lebih buruk. Vitamin D serum rendah juga telah ditemukan berhubungan dengan munculnya komplikasi DM seperti DKD dan PJK. Suplementasi vitamin D ditemukan paling baik untuk kontrol glikemik bila diberikan diberikan dalam dosis tinggi dan jangka pendek. Namun, belum dapat dipastikan bahwa suplementasi vitamin D efektif dalam kontrol glikemik karena hasil penelitian yang masih bertentangan. Kata Kunci: Vitamin D, Diabetes Mellitus Tipe 1, Diabetes Mellitus Tipe 2, Hba1c
Efikasi Liraglutide Dalam Tatalaksana Obesitas Pada Pasien Dewasa Diabetik dan Non-Diabetik Bramasta, Arya Adi; Novitasari, Diana
Malahayati Nursing Journal Vol 6, No 2 (2024): Volume 6 Nomor 2 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i2.12883

Abstract

ABSTRACT Obesity has become increasingly prevalent and is responsible for numerous other conditions like type 2 diabetes, hypertension, and cancer, contributing to a significant burden of disease. According to guidelines, managing obesity demands a multifaceted strategy that includes initiation of a comprehensive lifestyle intervention program and pharmacotherapy.  Currently, evidence has emerged of a new era of pharmacotherapy to support weight management, one of which is liraglutide. Liraglutide is a GLP-1 RA that has been proven to be effective effective for weight loss in both diabetic and non-diabetic patients. Apart from reducing body weight, liraglutide was also found to be useful in reducing HbA1c levels in diabetic patients. Currently,  liraglutide therapy for obesity is advised to be administered at a dose of 3 mg, with a gradual titration. The most common side effects are related to the gastrointestinal system such as nausea and vomiting.  Keywords: Liraglutide, Obesity, Overweight, Diabetes, Non-diabetes  ABSTRAK  Prevalensi obesitas telah meningkat pesat dan berhubungan dengan banyak penyakit lainnya seperti T2DM, hipertensi hingga kanker sehingga menimbulkan beban penyakit yang tinggi. Pedoman merekomendasikan pendekatan multifaktorial untuk tatalaksana obesitas, mencakup inisiasi program intervensi gaya hidup yang komprehensif dan farmakoterapi.  Saat ini telah muncul bukti era baru farmakoterapi untuk mendukung pengelolaan berat badan, salah satunya adalah liraglutide. Liraglutide adalah GLP-1 RA yang telah ditemukan efektif untuk menurunkan berat badan pada pasien diabetik dan non-diabetik. Selain menurunkan berat badan, liraglutide juga ditemukan bermanfaat dalam menurunkan kadar HbA1c pada pasien diabetik. Saat ini, penggunaan liraglutide direkomendasikan pada dosis 3 mg untuk terapi obesitas, dengan cara pemberian dititrasi perlahan. Efek samping yang paling umum terjadi yaitu terkait dengan sistem gastrointestinal seperti mual dan muntah.   Kata Kunci: Liraglutide, Obesitas, Overweight, Diabetes, Non-Diabetes
Occuli Dextra Proptosis in Symptomatic Hiperthyroidism with Diffuse Goitre in 45-Year-Old-Woman: A Case Report with Literature Review Novitasari, Diana
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i2.56798

Abstract

Thyroid hormones have been shown to impact the uptake and transportation of iron. By binding to a functioning TSH receptor, which is present in erythrocytes and certain extrathyroidal organs, TSH may have an effect on hematopoiesis. There are common causes for both poor thyroid status and anemia, which could account for the co-occurrence of low thyroid function and anemia. We report the case of 45 -year-old woman with major complaints of Swelling on her neck. Swelling on this patient occur with palpitations. On local examination of the neck area, there was visible mass during inspection, and on palpation there mass in the neck area. On laboratory examination, TSHs levels were 5.6 uIU/mL, FT4 levels were 128pmol/L, Hemoglobin 7.7 µg/dL. The patient underwent oral theraphy with using Salmon DNA on her diet and after 1 month control Her lab turn out very well with TSHs levels were 4,1 uIU/mL, FT4 levels were 22 pmol/L, Hemoglobin 10 µg/dL.
Co-Authors Al Aziz, Syaied Auliya Alexandra, Chrystella Axel Ashari, Shoimatul Fitriyah Asih, Devina Dewi AW Bramasta, Arya Adi Chyntia, Chyntia Elmaliyasari, Shifa Hidayah, Amellia Harmaimun Irmawati, Devi Johansen Johansen Kamila, Rosyidatul Karlasemi, easyka Rahmadina Kusumastuti, Erwin Maria Agustina Ermi Tri Sulistiyowati Naulina, Rosada Yulianti Negara, Tahta Rajesa Bihi Jaya Putra Ozzari, Nikita Aprilia Pawestri, Natasya Rahma Dewi Pratiwi, Nanda Aulia Putra, Ananda Putri, Dhini Awalia Rafli, Muhammad Arsyad Siti Zullaikah Timotius, Timotius Titanic, Pussof Yahyazucah Titanic, Pussof Yayazucah Trimono Wahyuni, Veronika Kristina Widia Astuti