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All Journal Jurnal Gizi dan Pangan Media Gizi Mikro Indonesia Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Teknosains Indonesian Journal of Biotechnology Mutiara Medika: Jurnal Kedokteran dan Kesehatan Sari Pediatri GIZI INDONESIA Indonesian Food and Nutrition Progress Berita Kedokteran Masyarakat
Mohammad Juffrie, Mohammad
Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Gadjah Mada/RSUP Dr. Sardjito, Yogyakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health

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Pengaruh Transfusi Trombosit Terhadap Terjadinya Perdarahan Masif pada Demam Berdarah Dengue Krisnanto Wibowo; Mohammad Juffrie; Ida S. Laksanawati; Sri Mulatsih
Sari Pediatri Vol 12, No 6 (2011)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp12.6.2011.404-8

Abstract

Latar belakang. Perdarahan masif merupakan salah satu komplikasi dan berhubungan dengan mortalitasyang tinggi pada demam berdarah dengue (DBD). Pemberian transfusi trombosit pada DBD merupakanterapi suportif yang memberikan efek terapi bila diberikan sesuai dengan indikasi yang tepat. Kegunaantransfusi trombosit masih kontroversial.Tujuan. Mengetahui pengaruh pemberian transfusi trombosit terhadap terjadinya perdarahan masif padaDBD.Metode. Penelitian merupakan penelitian kasus kontrol. Pasien dengan diagnosis DBD sesuai kriteria WHOyang dirawat di instalasi kesehatan anak RSUP Dr.Sardjito tahun 2006-2009 diteliti dari rekam medis. Kasusadalah pasien dengan perdarahan masif, sedangkan kontrol adalah pasien dengan perdarahan tidak masif.Hasil. Sepanjang tahun 2006-2009 terdapat 852 kasus DBD, terdiri dari 443 laki-laki (52%), 409 perempuan(48%), dan 35,7% adalah pasien DBD derajat II. Perdarahan masif terjadi pada 97 kasus (11%) yaituhematemesis 45 (46,4%), melena 20 (20,6%), hematemesis-melena 25 (25,8%), dan koagulasi intravaskulardiseminata 7 (8,2%). Perdarahan masif terbanyak terjadi pada jumlah trombosit <20.000/μL. Sebanyak67 pasien (7,8%) mendapat transfusi trombosit, 23 pada kelompok kasus dan 44 pada kelompok kontrol.Tidak ada perbedaan bermakna terjadinya perdarahan masif pada kedua kelompok tersebut (rasio odds1,39; interval kepercayaan 95% 0,79-2,45; p=0,29).Kesimpulan. Terjadinya perdarahan masif tidak dipengaruhi oleh transfusi trombosit.
Perbedaan Kadar Interferon Gamma pada Tuberkulosis Anak Sitti Ridha Khairani Fatah; Mohammad Juffrie; Amalia Setyati
Sari Pediatri Vol 18, No 5 (2017)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp18.5.2017.385-90

Abstract

Latar belakang. Tuberkulosis (TB) adalah penyakit akibat infeksi kuman Mycobacterium tuberculosis, suatu bakteri batang Gram positif. Salah satu sitokin yang diproduksi sel Th1 adalah interferon gamma (IFN-γ) yang berperan penting dalam mengeliminasi bakteri Mycobacterium tuberculosis. Terjadinya gangguan atau penurunan aktivitas sel Th1 dan sitokinnya yaitu IFN-γ cukup bermakna dalam memengaruhi mekanisme pertahanan tubuh terhadap penyakit TB. Manifestasi klinis penyakit TB terjadi karena adanya defisiensi imun, terutama imunitas selular. Tujuan. Mengkaji perbedaan kadar interferon gamma dilihat dari derajat lesi paru pada pasien TB anak. Metode. Penelitian cross sectional dilakukan di RSUP Dr. Sardjito and RSUD Sleman selama bulan Desember 2014. Subyek penelitian adalah anak kurang dari 15 tahun yang terdiagnosis TB menggunakan skor TB IDAI. Produksi interferon-gamma diukur dengan metode ELISA dan perbedaan kadarnya dibandingkan dengan derajat lesi paru.Hasil. Berdasarkan derajat lesi paru, kadar IFN-γ pada kasus tuberkulosis anak dengan lesi paru minimal (8,37±3,25) lebih tinggi daripada kasus dengan lesi paru sedang (3,52±1,75), dan lesi paru luas (4,83±2,78).Kesimpulan. Ada perbedaan rerata kadar IFN-γ serum TB anak berdasarkan derajat lesi paru minimal, sedang, dan luas, walaupun secara statistik tidak bermakna.
Pengaruh pendidikan kesehatan kombinasi metode simulasi dan media audiovisual terhadap pengetahuan dan sikap ibu terkait tatalaksana diare di rumah pada balita Aprilia Choirun Nisa; Akhmadi Akhmadi; Mohammad Juffrie
Berita Kedokteran Masyarakat (BKM) Vol 32, No 3 (2016)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.012 KB) | DOI: 10.22146/bkm.7419

Abstract

PurposeThis research aimed to determine the effect of health education related to the management of diarrhea at home in toddler. MethodsThis research was a quasi-experimental study using a pre and post test approach with control group. The sample population was all mothers who attended  Toddler Posyandu in Tiripan village and Ngepeh village, Nganjuk. Sampling technique used simple random sampling totalling 42 mothers in the intervention group and 49 mothers in the control group. Each group was given health education using audio-visual media while the intervention group was given a simulation after watching video. Simulation content included how to create, mix, and giving oralit, sign of dehydration in toddler, and also how to create, dissolve, and giving zinc tablet or syrup. The measurement instrument of mothers knowledge and attitude was made by the researcher  modified from Kapti which had been tested for validity and reliability. Post tests performed 1 week after the health education was given. ResultsIn both groups knowledge and attitude increased significantly after intervention with p=0.001. Changes of mothers knowledge and attitude in control and intervention were p=0.062 and p= 0.658, respectively. This result showed no significant difference in scores of knowledge and attitude of mothers in both groups. ConclusionThere were no significant differences in health education between using combination of simulation method and audiovisual media with increased knowledge and attitude in mothers.
The Consumption Effect of Indigenous Probiotic Powder Lactobacillus plantarum Dad-13 on Gut Microbiota Population and Short Chain Fatty Acids in Students of SMPN 1 Pangururan, Samosir Manurung, Nancy Eka Putri; Hasan, Pratama Nur; Juffrie, Mohammad; Utami, Tyas; Yanti, Rini; Rahayu, Endang Sutriswati
Indonesian Food and Nutrition Progress Vol 21, No 1 (2024)
Publisher : Indonesian Association of Food Technologists

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ifnp.86598

Abstract

The human intestine is a diverse ecosystem populated by microbiota affected by several factors, including age. The aim of this research was to evaluate the effects of the probiotic powder Lactobacillus plantarum Dad-13 on the numbers of gut microbiota, short-chain fatty acids (SCFA), and fecal characteristics in healthy adolescents. This research was conducted at SMPN 1 Pangururan, Samosir, with a randomized, double-blind, parallel placebo-controlled trial. 54 healthy adolescents aged 13 to 14 were divided into two groups, one consumed a gram of skimmed milk powder (placebo group) and the other ingested powder containing L. plantarum Dad-13 with 1.18 × 109 CFU/gram (probiotic group). After 33 days of intervention, the height of placebo group (149.42 ± 5.03 cm) and probiotic group (154.37 ± 4.67 cm) increased significantly. Significant increases in body weight (44.35 kg ± 4.61 to 45.20 kg ± 4.78) and BMI (and 18.77 ± 2.12 to 18.99 ± 2.11) were observed in the probiotic group. In the probiotic group, the numbers of gut microbiota were not significantly affected (p > 0.05). The amount of SCFA and fecal characteristics of both groups showed no significant differences. Thus, the consumption of L. plantarum Dad-13 increased weight, height, and BMI but could not influence the numbers of gut microbiota, SCFA, and the fecal characteristics of healthy adolescents.
KEADAAN MIKROBIOTA SALURAN CERNA PADA ANAK SEKOLAH DASAR YANG MENGALAMI STUNTING DI LOMBOK BARAT Helmyati, Siti; Yuliati, Endri; Wisnusanti, Setyo Utami; Maghribi, Risnhukathulistiwi; Juffrie, Mohammad
Jurnal Gizi dan Pangan Vol. 12 No. 1 (2017)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (324.971 KB) | DOI: 10.25182/jgp.2017.12.1.55-60

Abstract

The purpose of this study was to compare the population of gut microbiota between the normal height and stunted in primary school children in West Lombok. The study design was observational study with comparative design. The study involved 115 primary school students with age 9-12 years old by simple random sampling. The research data included the measurement of height for age and gut microbiota analysis of faecal samples. Based on the results of t-test, the number of bacteria Lactobacillus in stunting group (6.96±0.94 log CFU/g) were significantly (p <0.05) lower than normal group (7,38±0,98 log CFU/g). The population of Bifidobacteria, Enterobacter, and E. coli were not different between the two group. However the trend of Bifidobacteria count in stunting group (8.19±0.74 log CFU/g) was lower than normal group (8.22±0.79 log CFU/g) while the number of Enterobacter and E. coli in stunting group (7.82±0.68 and 7.03±0.97 log CFU/g) were higher than the normal group (7.71±0.81 and 6.96±1.22 log CFU/g).
Co-Authors Abd. Rasyid Syamsuri Adika Zhulhi Arjana Akhmadi Akhmadi Ali Djumhana Amalia Setyati Aprilia Choirun Nisa Ariani A, Ariani Arie Yulianto Budi Mulyono Djauhar Ismail Endang Sutriswati Rahayu Endri Yuliati Eva Yuniritha, Eva Harjono Ahmad, Harjono Hasan, Pratama Nur Helmyati, Siti I Gusti Wayan Murjana Yasa Ida S. Laksanawati Ida Safitri Laksono Ina Rosalina Indarto Indarto Irna Fajri Syahny Jamil, Muhammad Dawam Krisnanto Wibowo Kurniasari, Yulinda Maghribi, Risnhukathulistiwi Manurung, Nancy Eka Putri Marsetyawan HNE Soesatyo Marsetyawan HNE Soesatyo Mei Neni Sitaresmi Mirza Hapsari Sakti Titis Penggalih Neti Nurani Nur Kaliwantoro Pungky Ardany Kusuma Rini Dharmastiti Rini Yanti, Rini Sari, Endah Mayang Siti Helmyati Sitti Ridha Khairani Fatah Sofro, Zaenal Muttaqien Sri Mulatsih Suprihatin Suprihatin SUWIJIYO PRAMONO Toto Sudargo Tyas Utami Wahyu Damayanti, Wahyu Wisnusanti, Setyo Utami Yanri W Subronto Yunika Puspa Dewi