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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) JURNAL GIZI INDONESIA Prosiding Seminar Nasional MIPA Natural B Majalah Obat Tradisional Indonesian Journal of Chemistry Walisongo Journal of Chemistry Jurnal Media Sains Acta Chimica Asiana Jurnal Pengabdian kepada Masyarakat Seminar Ilmiah Nasional Teknologi, Sains, dan Sosial Humaniora (SINTESA) Seminar Nasional Aplikasi Iptek (SINAPTEK) Paradharma: Jurnal Aplikasi IPTEK
I Made Wisnu Adhi Putra
University Of Dhyana Pura
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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PENINGKATAN PENGETAHUAN DAN KETERAMPILAN KELOMPOK PENGOLAH DAN PEMASAR (POKLAHSAR) MINA LESTARI BATU LUMBANG DENPASAR MELALUI PEMBUATAN MINUMAN HERBAL DAUN JERUJU I Made Wisnu Adhi Putra; Putu Angga Wiradan; A.A.A. Putri Permatasari
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 9: Februari 2025
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jabdi.v4i9.9607

Abstract

Kelompok Pengolah dan Pemasar (Poklahsar) Mina Lestari merupakan kelompok yang dibentuk selama Pandemi COVID-19 di Ekowisata Mangrove Batu Lumbang, Denpasar, Bali. Kelompok ini mengembangkan Hasil Hutan Bukan Kayu (HHBK) yang berbasis hutan mangrove. Beberapa produk yang sudah dibuat meliputi: produk olahan makanan ringan, minuman tradisional, fashion, dan produk lulur. Salah satu produk yang menjadi unggulan Poklahsar sebagai mitra adalah simplisia daun Jeruju. Selama menjalankan usahanya, mitra mengalami beberapa masalah diantaranya adalah: mitra masih belum mengenal secara jelas bagian-bagian mangrove yang dapat digunakan untuk produk pangan dan kesehatan, sehingga produk yang bisa dihasilkan sedikit, masa simpan simplisia yang terlalu singkat dan rentan berjamur yang membuat daya jual produk menjadi rendah, dan pengunjung/pembeli tidak bisa menikmati minuman daun jeruju secara langsung karena tidak adanya bentuk yang bisa diminum secara langsung. Metode Pelaksanaan dalam menyelesaikan permasalahan mitra adalah dengan penyuluhan dan pendampingan terkait permasalahan yang dihadapi oleh mitra. Kegiatan ini memberikan hasil yang sangat memuaskan. Setelah diberikan penyuluhan, mitra akhirnya memahami tentang pemanfaatan hasil turunan tumbuhan mangrove sebagai bahan baku obat tradisional dan makanan serta memahami bagaimana cara mengolah daun jeruju, mulai dari panen, penyortiran, pengeringan dengan oven, pembuatan serbuk simplisia menggunakan grinder, hingga pengemasan dan penyimpanan. Selain itu, mitra juga akhirnya mengetahui cara lain untuk membuat minuman herbal dengan teknik infusa. Teknik infusa terbukti mampu mengekstrak lebih banyak senyawa fitokimia dari daun jeruju yang dibuktikan dengan warna minuman yang keruh kecoklatan serta rasa dan aroma yang khas daun jeruju
EVALUATION OF PHOSPHOMOLYBDENUM AND FERRIC REDUCING ANTIOXIDANT POWER ASSAYS IN EXTRACT COMBINATIONS OF MANGIFERA INDICA AND EUPHORBIA HIRTA Putra, I Made Wisnu Adhi; Suarjana, Nyoman
Walisongo Journal of Chemistry Vol. 8 No. 1 (2025): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology UIN Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v8i1.25580

Abstract

Combining plant extracts at lower doses may enhance antioxidant effects through synergy. This study investigated the antioxidant capacity of combined Mangifera indica and Euphorbia hirta leaf extracts using metal ion-reducing power assays. The extracts were prepared via maceration with 70% ethanol. Phytochemical profiling was conducted through preliminary screening tests. Antioxidant capacity was assessed spectrophotometrically using the phosphomolybdenum and ferric reducing antioxidant power (FRAP) assays. The phosphomolybdenum assay involved incubation of the extracts with reagent at 95°C for 90 minutes, while the FRAP assay was conducted at 37°C for 15 minutes. Extract combinations were prepared in the ratios of 1:3, 1:1, and 3:1. Phytochemical screening revealed the presence of alkaloids, phenolics, flavonoids, steroids, and terpenoids in both extracts. In the phosphomolybdenum assay, the Mo(VI) reducing power of M. indica extract (29.154±0.664 mg AAE/g extract) was higher than that of E. hirta (27.948±0.667 mg AAE/g extract). Similarly, in the FRAP assay, the ferric reducing power of M. indica extract (55.304±1.284 mg AAE/g extract) exceeded that of E. hirta (48.009±1.873 mg AAE/g extract). The highest reducing powers were observed in Comb. 3, yielding 30.745±0.715 mg AAE/g extract (phosphomolybdenum) and 57.190±1.431 mg AAE/g extract (FRAP). Among the three combinations tested, only the 3:1 ratio demonstrated a synergistic antioxidant effect in both assays.
A Synergistic Effect of Free Radical Scavenging Activity of the Combination of Mangifera indica and Euphorbia hirta Extracts Putra, I Made Wisnu Adhi; Suarjana, Nyoman; Mahfur, Mahfur; Hasnawati, Hasnawati
Indonesian Journal of Chemistry Vol 25, No 5 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.104706

Abstract

Due to its synergistic effect, the extract-extract combination is essential in traditional medicine formulation. The combination of Mangifera indica and Euphorbia hirta extracts can produce a synergistic effect if combined in a proper ratio. This investigation reported the synergistic antioxidant effect of M. indica and E. hirta. The ethanolic extracts of M. indica leaf (MILE) and E. hirta aerial part (EHAE) were acquired by the maceration method, followed by evaporation to remove the solvent. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) tests were used to assess the extracts' capacity to scavenge radicals. MILE and EHAE were combined with a ratio of 1:3 (comb. 1), 1:1 (comb. 2), and 3:1 (comb. 3). This work disclosed that the extract combinations showed all types of interactions. However, of all combinations, only comb. 3 depicted the synergistic interaction caused by the regeneration effect of EHAE on MILE. This finding has important implications for health, particularly disease prevention. M. indica and E. hirta extracts with high phenolic and flavonoid contents can work together to reduce oxidative stress and protect the body from a variety of diseases.
Effect of different solvents on antioxidant activity of Euphorbia hirta L. extract Suarjana, Nyoman; Nyandra, Made; Astuti, Ni Putu Widya; Kurniati, Ni Made; Sumadewi, Ni Luh Utari; Putra, I Made Wisnu Adhi; Andrianto, Nurrahman
Acta Chimica Asiana Vol. 8 No. 2 (2025)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v8i2.256

Abstract

Euphorbia hirta L. is a species of plant renowned for its antioxidant properties. However, the optimal solvent for extracting these bioactive compounds to maximize antioxidant activity had not been systematically identified and compared. Previous knowledge suggested that solvent choice affects yield and efficacy; however, there was a lack of conclusive, comparative data specifically for E. hirta extracts using different solvents. The focus of this work was to investigate how different solvents affected the content of phenolics and flavonoids, as well as the antioxidant effect of E. hirta extract. The aerial part of E. hirta powder was extracted with ethanol, ethyl acetate, and n-hexane to obtain the crude extracts. Folin-Ciocalteu reagent and AlCl3 solution were used to assess the total phenolic and flavonoid contents, respectively. The ferric reducing antioxidant power (FRAP), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) techniques were used to assess antioxidant activity. The total content of phenolics and flavonoids of E. hirta ethanol extract (127.827 ± 2.609 mg GAE/g extract and 28.507 ± 0.464 mg QE/g extract, respectively) was substantially higher than that of the other extracts (p<0.0001). The findings of the FRAP test exhibited that the E. hirta ethanol extract (48.009 ± 1.873 mg AAE/g extract) had a substantially greater reducing power value (p<0.0001) in comparison to other extracts. The ethanol extract of E. hirta had a considerably lower IC50 value (6.154 ± 0.063 ppm and 9.429 ± 0.183 ppm for DPPH and ABTS assays, respectively, with p<0.0001) than the other extracts. This study found that solvent polarity had a substantial influence on the antioxidant activity of E. hirta extracts, with ethanol being an optimal solvent for the extraction procedure.
Co-Authors A.A.A. Putri Permatasari Adiari, Ni Wayan Lisa Ana Malia Andrianto, Nurrahman Ate, Olyn Tien Atikawati, Atikawati Hasnawati Hasnawati I Gede Mustika I Gede Widhiantara I Gusti Ayu Wita Kusumawati I Made Gde Sudyadnyana Sandhika I Made Murna I Nengah Simpen I Wayan Rosiana I. A. R. Astiti Asih Ida Bagus Agung Yogeswara Indriana Kartini Indriana Kartini Ketut Ayu Sukesi Krismawintari, N.P.D. Made Agung Raharja Made Nyandra Mahfur, Mahfur Ni Kadek Dwipayani Lestari NI KADEK YUNITA SARI Ni Luh Utari Sumadewi Ni Made Kurniati Ni Putu Eny Sulistyadewi Ni Putu Widya Astuti Ni Wayan Nursini Nyoman Suarjana Permatasari , A.A. Ayu Putri Permatasari, Anak Agung Ayu Putri Putu Angga Wiradan Putu Angga Wiradana Putu Suarya Rahmadi Prasetijo Sandhika, I Made Gde Suadnyana Sitanggang, Katrin Walensky Sumadewi, Ni Luh Utari Wiradana , Putu Angga Yateman Arryanto Yateman Arryanto