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Bayu Putra, Bayu
bayuputra.pharm@gmail.com
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Journal : Jurnal Fitofarmaka Indonesia

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Potential of Extract of Tamarindus Indica L Leaves an Anti-Inflammatory on Carrageenan Induced Wistar Rats Wati, Aulia; Sukmawati, Sukmawati; Putra, Bayu
Jurnal Fitofarmaka Indonesia Vol 10, No 3 (2023): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v10i3.1107

Abstract

Tamarind leaves are used in traditional medicine for inflammation, stomach pain, rheumatism, and sore throats. The aims of this study was to determined the potential of extract tamarind leaf as an anti-inflammatory in Wistar rats. This study was used experimental rats divided into 5 groups, namely group I was given Na. CMC, group II was given diclofenac sodium dose of 5.136 mg/kgBW, groups III, IV, and V were given ethanol extract of tamarind leaves at a doses of 250, 500 and 1000 mg/kgBW. The test animals induced with 1% lambda carrageenan by intraplantar after one hour given test preparation orally. Measurements of edema volume and thickness of the rats were carried out before and after induction for 7 hours at 1 hour intervals using a pletysnometer and calipers. The research data was calculated statistically using the one way anova test and Post Hoc LSD. The results of the study showed that the extract group at a dose of 1000 mg/kgBW had an anti-inflammatory effect not significantly different compared to  the diclofenac sodium group at a dose of 5.136 mg/kgBW. Therefore, obtained results showed that the extract of tamarind leaf  has an anti-inflammatory effect with an effective dose of 1000 mg/kgBW.
Co-Authors , Faradiba Abdul Malik Ahmad, Aktsar Roskiana Alani, Fitri Wasto Alda, Alda Alfani, Ajeng Khori Amara, Ressa Andi Emelda Andi Maulana Kamri Arini Arini Ashar, Muhammad Affan Asriani Suhaenah Aulia Wati, Aulia Awali, Muhammad Noer Dedi Setiawan Dewi Yuliana Ehwanudin Ehwanudin, Ehwanudin Fadlina Chany Saputri Fitriana Fitriana Fitriana Hasbullah, Nurhijjah Hativa, Hativa Irma Santi, Irma Iskandar , A. Nasyrah Isyanda, Kenanga Maghfiroh, Ummu Majid, Wahid Abdul Muarsih, Ahmad Juniardhy Multazania, Multazania Munir, Sahrul Mustakim, Putri Dwiyanti Adha Mustofa, Ahmad Ihzal Nirmala, Maiyuni Nopriyanti, Eka Maryam Nur Aisyah, Irna Nissa Nurul Afiah Nurung, Ayyub Harly Rachmat Kosman, Rachmat Rahman, Safriana Rakhmat, Syahgita Ramadhani, Fitrah Anggun ramadhani, novita annur Resvani, Syahyu Rizqi Nur Azizah Rosyid, Ahmad Sihabudin Rusli Safriani Rahman, Safriani sahab, Fitria SALIM, MUH.AGUS Saputra, Rizki Maulana Siska Nuryanti, Siska Sitti Amirah Sukmawati Sukmawati Syahrul, Andi Ahmad Yundari, Yundari Zuniati, Mai