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All Journal Jurnal Sain Veteriner Jurnal Pelita Pendidikan Jurnal Teknologi Pendidikan Jurnal Pendidikan Biologi Biosfer: Jurnal Pendidikan Biologi Bioedukasi: Jurnal Pendidikan Biologi Jurnal Penelitian Pendidikan, Psikologi Dan Kesehatan (J-P3K) JURNAL BIOSHELL Bioscientist : Jurnal Ilmiah Biologi Jurnal Pengabdian Teknologi Tepat Guna Journal of Biology Education
Herbert Sipahutar, Herbert
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Nursing Public Health Social Sciences Veterinary

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Pengaruh Ekstrak Etanol Daun Bosibosi (Timonius flavescens (Jacq.) Baker) terhadap Jumlah Folikel Ovarium Tikus Putih (Rattus norvegicus) yang Diinduksi Bisphenol A Panjaitan, Melisa Lidwina; Sipahutar, Herbert
Jurnal Sain Veteriner Vol 43, No 3 (2025): Desember
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.107589

Abstract

Kehadiran BPA sebagai pengganggu endokrin dalam kehidupan manusia telah memberikan dampak negatif terutama pada kondisi kesehatan. Upaya untuk menemukan bahan alami yang murah, aman dan efektif untuk mengobati penyakit akibat toksisitas BPA menjadi semakin penting. Penelitian ini bertujuan untuk mengetahui potensi pemberian ekstrak etanol daun bosibosi ( Timonius flavescens (Jacq.) Baker) terhadap jumlah folikel ovarium tikus putih (Rattus norvegicus) yang menginduksi BPA. Adapun parameter yang diamati yaitu berat badan, berat organ ovarium, rasio berat ovarium, jumlah folikel primer dan folikel sekunder. Tikus dibagian menjadi menjadi 6 kelompok (1 kelompok terdiri dari 6 ekor tikus). Kelompok I tikus hanya diberi pakan dan minum. Kelompok II, diberi 0,5 ml minyak jagung. Kelompok III, diberi BPA 50 mg/kg/hari. Kelompok IV, diberi BPA 50 mg/kg/hari+EEDB 225 mg/kg/hari. Kelompok V, diberi BPA 50 mg/kg/hari+EEDB 250 mg/kg/hari. Kelompok VI, diberi BPA 50 mg/kg/hari+EEDB 500 mg/kg/hari. Pemberian perlakuan dilakukan secara lisan selama 30 hari. Hasil analisis Uji ANOVA menunjukkan perbedaan yang signifikan (p < 0,05) terhadap berat badan. Pada berat organ dan rasio berat organ tidak terdapat perbedaan yang signifikan (p > 0,05). Namun pemberian BPA dan esktrak etanol daun bosibosi berpengaruh signifikan (p < 0,05) terhadap jumlah folikel primer dan folikel sekunder. Berdasarkan hasil penelitian dapat disimpulkan bahwa ekstrak etanol daun bosibosi memelihara jumlah folikel primer dan folikel sekunder pada ovarium.Kata kunci: Bisfenol A; ekstrak etanol daun bosibosi; folikel primer; folikel Sekunder
The Effect of Interactive Digital Learning Module on Student’s Learning Activity and Autonomy Tarigan, Wenny Pinta Litna; Sipahutar, Herbert; Harahap, Fauziyah
Bioedukasi: Jurnal Pendidikan Biologi Vol 14, No 2 (2021): Bioedukasi: Jurnal Pendidikan Biologi
Publisher : Department of Biology Education Faculty of Teacher Training and Education Sebelas Maret Un

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/bioedukasi-uns.v14i2.49366

Abstract

In the modern society, the internet breaks through the restrictions on time and space and becomes a ubiquitous learning tool. Designing teaching activity for digital learning and flexibly applying technology tools are the key issues for current information technology integrated education. Interactive learning modules could be used in the classroom environment for effective learning. This study explored the effect of instructional modules for providing supplementary instruction in biology concepts. Interactive digital learning module was developed in order to assist students in biology learning. Interactive activities were considered in this study, include teacher – student interaction, student - student interaction, student - content interaction, and student - technology interaction. 180 students of Grade 11 in 6 classes at SMAN 2 Balige were selected as the research subjects. Three groups of students participated in biology learning course, (2 classes) using different modules were interactive digital module, digital module and text module. Goal of this research was to determine the impact of interactive digital learning module on students’ learning activity and autonomy. Quantitative results obtained by using questionnaire to understand the student’s learning activity and autonomy. Results showed student’s activities and autonomy who learned with interactive digital learning modules significantly different with students who learned using text learning modules. The use of interactive features increased the activity and autonomy of learners and created the student-centered learning environment. Students under interactive multimedia instruction performed better than text module class. These findings suggested that learning activity and autonomy of students in biology could be enhanced by multimedia instruction.
Co-Authors A.A. Ketut Agung Cahyawan W Agustina, Rezeki Sri Azimar Rusdi, Azimar Cristanty, Rina Dedy Husrizal Syah, Dedy Husrizal Deo Demonta Panggabean Diningrat, Diky Setya Doloksaribu, Maryati Evivani Ely Djulia Fauziyah Harahap Istiqomah, Khazanah Jonny Haratua Panggabean, Jonny Haratua Lestari, Sri Ratna Limbong, Forentina Mukti Hamjah Harahap, Mukti Hamjah Nasution, Marina Azzahra Natalia Kristiani Lase, Natalia Kristiani Panjaitan, Melisa Lidwina Renny Agustina, Renny Sapitri, Alfi Saragih, Juwanda Pranata Sembiring, Rinawati Sembiring, Surya Karinanta Sinambela, Aslinda Sipahutar, Melati Sri Agnes Sipayung, Yariski Sitanggang, Lawren Siti Khadizah Harahap, Siti Khadizah Susanty, Revi Ruth Syahmi Edi Syarifuddin Syarifuddin Tarigan, Lola Zeramenda Tarigan, Wenny Pinta Litna Tri Effiyanti Tri Harsono Turnip, Ayu Monita