Garuda - Garba Rujukan Digital

Comparison Of Reduction In Blood Pressure Between Sublingual and Oral Captopril Agustiawan, Agustiawan; Tabari, Muhammad Fadhlan La; Ilvira, Muhammad Natsir; Mastari, Ekawaty Suryani; Hardiyanti, Dwi
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 4 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i4.1794

Background: Hypertensive crisis poses a high risk for long-term cardiovascular complications, and management focuses on controlled blood pressure (BP) reduction rather than immediate normalization. Objective: To compare the effectiveness of sublingual and oral captopril in reducing BP among patients with hypertensive urgency. Methods: A literature review was conducted using English-language studies published after 2012 that evaluated BP reduction outcomes of sublingual versus oral captopril. Results: Three relevant studies met the inclusion criteria, comparing both administration routes in hypertensive urgency management. All studies demonstrated that sublingual and oral captopril were similarly effective in lowering systolic and diastolic BP within the first few hours after administration. Sublingual captopril consistently produced a faster onset of action, with BP reduction observed within 15–30 minutes, whereas oral administration required 30–60 minutes to achieve comparable effects. None of the studies reported significant differences in adverse effects between the two routes. These findings suggest that while overall efficacy is comparable, the sublingual route provides more rapid BP control, which may be crucial in acute care settings. Conclusion: Both sublingual and oral captopril are effective options for hypertensive urgency, with the sublingual form offering a faster therapeutic response suitable for rapid BP reduction in emergency situations.

Dampak Penggunaan Gadget Pada Kesehatan Mental Remaja Di SMA Swasta Nur Ihsan Medan Mastari, Ekawaty Suryani; Hrp, Fitri Aidani Ulfa; Nasution, Fahmi Irsan; Saputra, Ahmad Yayang; Alesha, Jane
Marsipature Hutanabe: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 01 (2024): Marsipature Hutanabe: Jurnal Pengabdian Kepada Masyarakat
Publisher : CV. Devi Tara Innovations

Show Abstract | Download Original | Original Source | Check in Google Scholar

Mental health problems have become an unresolved health problem in the midst of society, both at the global and national levels. Especially during the COVID-19 pandemic, mental health problems will be increasingly difficult to solve. The increasingly worrying condition of people's mental health will affect national productivity. According to WHO, mental health refers to a person's well-being condition, when a person is aware of his or her abilities, is able to manage his or her stress and adapts well, can work productively, and contributes to his environment. Current technological developments also affect mental health, including the use of gadgets. Gadgets make it easy to access information, communicate with others, and do various online activities. However, excessive use of gadgets can have a negative impact on the mental and physical health of users, especially at the age of children and adolescents, The influence of gadgets can result in children being hampered in interacting even in the family environment, easily bored and difficult to concentrate, especially in learning, and interfering with their cognitive development. According to a survey in Indonesia according to Research by Kominfo and the United Nations Children's Fund (2014), the use of social media and digital is an integrated part of the daily life of young people in Indonesia. The study found that 98% of the children and adolescents surveyed knew about the internet and that 79.5% of them were internet users. In addition, there are still few parents who supervise their children when accessing the internet or playing layer media. Prevention and handling of metal health disorders due to the use of gadgets requires the role of various parties, including government policies, parents and families, and the role of the school environment. Socialization in the environment around children, especially schools, is one of the keys.

Edukasi Pentingnya Menjaga Kesehatan Mental Pada Anak Remaja Di SMA Negeri 3 Binjai Hrp, Fitri Aidani Ulfa; Mastari, Ekawaty Suryani; Wahyuni, Ningrum; Tarigan, Emilia Putri; Nuha, Farhah Kamilatun
Marsipature Hutanabe: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 01 (2024): Marsipature Hutanabe: Jurnal Pengabdian Kepada Masyarakat
Publisher : CV. Devi Tara Innovations

Show Abstract | Download Original | Original Source | Check in Google Scholar

Mental health problems have become unresolved health problems in society, both at the global and national levels. Especially during the COVID-19 pandemic, mental health problems will be more difficult to solve. The increasingly concerning condition of people's mental health will affect national productivity. This could hinder Indonesia from transitioning into a developed country by 2045. Mental health services are crucial and require the same attention as physical health. According to the Indonesia-National Adolescent Mental Health Survey 2022, 15.5 million (34.9 percent) adolescents experience mental problems and 2.45 million (5.5 percent) adolescents experience mental disorders. Of that number, only 2.6 percent accessed counseling services, both emotional and behavioral. The government has been thinking about mental health, but it has not been a priority. Access to mental health services is expensive and not inclusive. Meanwhile, attention to mental and physical health has not been equal in national health insurance. In Indonesia, we know many cases of adolescents aged 15-17 who experience excessive anxiety resulting in depression and suicide.

Skrining Kesehatan Remaja Kolaborasi Institut Kesehatan Helvetia Medan dan Universiti Sultan Zainal Abidin Malaysia di SMP Amanah 1 Medan Harahap, Fitri Aidani Ulfa; Mastari, Ekawaty Suryani
Nanggroe: Jurnal Pengabdian Cendikia Vol 4, No 9 (2025): December 2025
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.18041776

Adolescent health screening is an important strategy for the early detection of common health problems among school-aged students. This activity was conducted through an academic collaboration between the Institut Kesehatan Helvetia (IKH) Medan, Indonesia, and Universiti Sultan Zainal Abidin (UniSZA), Malaysia, as part of an international community engagement program. The health screening program implemented at SMP Amanah 1 included anthropometric measurements, blood pressure assessment, personal hygiene evaluation, nutritional status assessment, and identification of basic health complaints. The purpose of this activity was to obtain an overview of students’ health status while simultaneously increasing their awareness of the importance of healthy lifestyle behaviors. The program was carried out using a structured approach involving direct physical examinations, brief interviews, and health education sessions. The screening results indicated that a proportion of students were still at risk of nutritional problems and exhibited unhealthy lifestyle habits. International academic collaboration enhanced the quality of the screening process through the exchange of examination practices and educational approaches. This activity is expected to serve as a promotive–preventive model that can be implemented in other school settings. Overall, the screening program made a meaningful contribution to efforts to improve adolescent health, increased students’ understanding of the importance of regular health monitoring, and strengthened teachers’ capacity to support healthy habits at school. Furthermore, the screening findings may serve as a basis for developing more targeted follow-up health interventions. Thus, health screening based on international collaboration has significant potential to strengthen adolescent health in the long term.

EDUKASI KESEHATAN TENTANG FAKTOR RISIKO DAN PENCEGAHAN DIABETES DI KELURAHAN LABUHAN DELI, MEDAN MARELAN TAHUN 2022 Noradina Noradina; Meriani Herlina; Ekawaty Suryani Mastari; Christina Magdalena T.Bolon
Jurnal Pengabdian Ilmu Kesehatan Vol. 2 No. 2 (2022): Juli: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v2i2.283

Diabetes sebagai penyakit metabolik, merupakan penyakit yang berhubungan erat dengan gaya hidup masyarakat. Penyakit ini berhubungan dengan beban sosioekonomi yang tinggi secara global dan regional. Terjadinya diabetes dipengaruhi oleh faktor risiko yang dibagi menjadi faktor risiko yang dapat dimodifikasi dan faktor risiko yang tidak dapat dimodifikasi. Pencegahan penyakit diabetes melitus tipe 2 mengurangi risiko yang dapat dimodifikasi terutama kepada orang-orang yang memiliki risiko untuk menderita DM tipe 2. Penelitian di berbagai negara termasuk Indonesia menunjukkan bahwa pengetahuan masyarakat mengenai Diabetes Melitus masih belum optimal. Tujuan dari program pengabdian masyarakat ini adalah untuk meningkatkan pengetahuan tentang faktor risiko dan pencegahan diabetes pada masyarakat baik yang berisiko diabetes maupun yang tidak berisiko dengan memberikan edukasi di Kelurahan Labihan Deli, Medan Marelan.

DETEKSI DINI GANGGUAN MINERAL TULANG PADA PENYAKIT GINJAL KRONIK: TINJAUAN SISTEMATIK: EARLY DETECTION OF BONE MINERAL DISORDERS IN CHRONIC KIDNEY DISEASE: A SYSTEMATIC REVIEW Agustiawan; Sugianto Mukmin; Ekawaty Suryani Mastari; Amanda Trixie Hardigaloeh; Denny Susanto
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Vol. 25 No. 1 (2026): Januari 2026
Publisher : Faculty of Medicine Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/ibnusina.v25i1.1052

Gangguan metabolisme mineral dan tulang merupakan komplikasi penting pada pasien penyakit ginjal kronik yang berdampak pada meningkatnya morbiditas, mortalitas, dan risiko fraktur tulang. Tinjauan sistematik ini bertujuan untuk menganalisis bukti terkini mengenai peran biomarker biokimia dan pemeriksaan radiologis dalam deteksi dini CKD-MBD pada pasien CKD stadium 2–5. Pencarian literatur dilakukan melalui PubMed, Scopus, dan ScienceDirect untuk periode 2015–2025. Empat studi yang memenuhi kriteria inklusi berasal dari India, Italia, Tiongkok, dan Bangladesh, dengan desain potong lintang dan kohort prospektif. Bukti yang kami himpun menunjukkan bahwa peningkatan kadar parathyroid hormone (PTH), fosfat, alkaline phosphatase (ALP), dan fibroblast growth factor-23 (FGF-23) secara konsisten berhubungan dengan penurunan bone mineral density (BMD) serta progresivitas CKD. Kombinasi pemeriksaan biokimia dengan densitometri tulang (DXA) dan pendekatan berbasis machine learning terbukti meningkatkan akurasi diagnosis dini. Oleh karena itu, pemantauan biomarker tersebut dapat menjadi strategi penting dalam deteksi dan pencegahan CKD-MBD secara komprehensif.

Evaluasi Pola Penggunaan Obat Tradisional dan Swamedikasi di Desa Bireuen Meunasah Blang Muhammad Natsir Ilvira; Fahmi Irsan Nasution; Hanafis Sastra Winata; Bayu Irvia Satria; Ekawaty Suryani Mastari
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.501

The use of traditional medicine has long been integral to Indonesian society, offering affordable and accessible healthcare options. This study evaluates the patterns of traditional medicine use in Bireuen Meunasah Blang Village, focusing on respondent demographics, self-medication practices, and perceptions of affordability, effectiveness, and accessibility. Using a descriptive quantitative design, data were collected from 97 respondents aged 18–60 years through structured questionnaires. Results indicate that 54.6% of respondents demonstrate adequate use of traditional medicine, while 76.3% follow appropriate usage guidelines. Perceptions of cost and availability were predominantly positive, with 48.5% finding traditional medicines affordable and 70.1% familiar with their names. However, knowledge of side effects and sources of information remains limited. These findings underline the need for targeted public health education to enhance safe and informed self-medication practices with traditional medicines.

Peran Polimorfisme GeN MMP-9-1562C/T Terhadap Kejadian Retinopati Diabetik Pada Pasien DM Ekawaty Suryani Mastari
Journal of Health and Medical Science Volume 1 Nomor 4 Oktober 2022
Publisher : CV. Pusdikra Mitra Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51178/jhms.v1i4.980

Retinopati diabetik merupakan komplikasi neurovaskular pada diabetes yang melibatkan kerusakan sawar-darah retina. Peran matriks metalloproteinase dalam mendegradasi matriks ekstrasel memperantarai kerusakan sel endotel retina dan proliferasi vaskular. Matriks metalloproteinase-9 (MMP-9) telah diketahui berperan pada inflamasi dan neovaskularisasi retina. Oleh karenanya, polimorfisme MMP-9 -1562C/T dianggap berperan pada risiko terjadinya retinopati diabetik. Penelitian ini merupakan studi cross-sectional dengan 52 pasien retinopati diabetik dan 42 pasien DM tanpa komplikasi sebagai kontrol. Pemeriksaan polimorfisme gen MMP-9 -1562C/T dilakukan dengan teknik PCR-RFLP. Perbedaan frekuensi proporsi genotip dan alel kedua kelompok dianalisis dengan uji chi square. Diperoleh frekuensi genotip CC 75%, CT 23,1%, dan TT 1,9% pada kelompok kasus serta genotip CC 54,8%, CT 45,2% dan tidak dijumpai genotip TT pada kelompok kontrol. Uji keseimbangan Hardy-Weinberg pada frekeunsi genotip menunjukkan kesesuaian (p>0,05). Uji proporsi frekuensi genotip dan alel pada kelompok kontrol dan kelompok kasus menunjukkan tidak adanya perbedaan bermakna (p>0,05). Polimorfisme gen MMP-9 -1562C/T bukan merupakan faktor risiko utama terjadinya retinopati diabetik pada pasien DM

Skrining Kesehatan Remaja Kolaborasi Institut Kesehatan Helvetia Medan dan Universiti Sultan Zainal Abidin Malaysia di SMP Amanah 1 Medan Fitri Aidani Ulfa Harahap; Ekawaty Suryani Mastari
Nanggroe: Jurnal Pengabdian Cendikia Vol 4, No 9 (2025): December 2025
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.18041776

Adolescent health screening is an important strategy for the early detection of common health problems among school-aged students. This activity was conducted through an academic collaboration between the Institut Kesehatan Helvetia (IKH) Medan, Indonesia, and Universiti Sultan Zainal Abidin (UniSZA), Malaysia, as part of an international community engagement program. The health screening program implemented at SMP Amanah 1 included anthropometric measurements, blood pressure assessment, personal hygiene evaluation, nutritional status assessment, and identification of basic health complaints. The purpose of this activity was to obtain an overview of students’ health status while simultaneously increasing their awareness of the importance of healthy lifestyle behaviors. The program was carried out using a structured approach involving direct physical examinations, brief interviews, and health education sessions. The screening results indicated that a proportion of students were still at risk of nutritional problems and exhibited unhealthy lifestyle habits. International academic collaboration enhanced the quality of the screening process through the exchange of examination practices and educational approaches. This activity is expected to serve as a promotive–preventive model that can be implemented in other school settings. Overall, the screening program made a meaningful contribution to efforts to improve adolescent health, increased students’ understanding of the importance of regular health monitoring, and strengthened teachers’ capacity to support healthy habits at school. Furthermore, the screening findings may serve as a basis for developing more targeted follow-up health interventions. Thus, health screening based on international collaboration has significant potential to strengthen adolescent health in the long term.

Uji efektivitas salep kombinasis Nothopnax sculleturium (daun mangkokan) dan Colocasia esculenta L. (daun talas) terhadap penyembuhan luka sayat kelinci jantan Ekawaty Suryani Mastari; Hanafis Sastra Winata; Ruth Mayana Rumanti; Sari Bulan Novita
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1739

Background: Nothopanax scutellarium (mangkokan leaves) and Colocasia esculenta L. (taro petioles) contain bioactive compounds such as flavonoids, saponins, tannins, terpenoids, and steroids, which play essential roles in wound healing. Objective: This study aimed to evaluate the effectiveness of a topical ointment containing a combination of ethanolic extracts of mangkokan leaves and taro petioles on incised wound healing in male rabbits. Methods: A laboratory experimental study with a post-test-only control group design was conducted using three ointment formulas (10%:5%, 7.5%:7.5%, and 5%:10%), alongside positive (povidone-iodine) and negative controls. Wound length was measured daily for 10 days. Data were analysed using one-way ANOVA followed by Tukey's post-hoc test at a significance level of α = 0.05. Results: All formulations significantly accelerated wound healing compared with the negative control (p < 0.05). The 5%:10% formulation achieved complete wound closure on day 7, showing a statistically significant difference from the positive control (p < 0.05). Conclusion: The combination of mangkokan leaf and taro petiole extracts effectively promotes incised wound healing, with the 5%:10% formula demonstrating the most optimal effect. These findings support the potential of developing this herbal ointment as a safe and efficient antiseptic alternative.

Title

Found 20 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 20 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 20 Documents
Search