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All Journal Alotrop Jurnal Pendidikan dan Ilmu Kimia Justek : Jurnal Sains Dan Teknologi JFL : Jurnal Farmasi Lampung Jurnal FARMAKU (Farmasi Muhammadiyah Kuningan) Indonesian Journal of Pharmaceutical Education Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Jurnal AFAMEDIS Jurnal Farmasi Komunitas Medical Sains : Jurnal Ilmiah Kefarmasian Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) Parapemikir Jurnal Ilmiah Farmasi Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian
ERNA FITRIANY, ERNA
Akademi Farmasi Mitra Sehat Mandiri Sidoarjo
Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Uji Mutu Fisik Metoklopramid HCl Tablet Chewable dengan Variasi Jenis Pengisi sebagai Diluent menggunakan Metode Granulasi Basah Latifiana, Umi; Budi Legowo, Deny; fitriany, erna; Priyoherianto, Andri; Novianto Ainul Huri, Muhammad
Indonesian Journal of Pharmaceutical Education Vol 1, No 2 (2021): Mei-Agustus 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i2.10638

Abstract

Metoclopramide HCl are used to reduce vomiting and nausea. The availability on the market in the form of tablet, syrup and injection. Patient tend to prefer take drugs by oral use because it was easier. Chewable tablet is the new product as the alternative ways to treatment children and adult patient who had difficulity problem of swallowing drugs. Objectives: This research aims to formulate the chewable metoclopramide HCl tablets using diluent variations to get a better physical quality test. Chewable tablets of metoclopramide HCl are made using diluent variations, they are mannitol, sucrose, lactose. Formula I mannitol, formula II sucrose, and formula III lactose. Chewable tablet preparations are made by the wet granulation method. Data collection was performed on physical characteristics including organoleptic, weight uniformity, uniformity of size, tablet hardness, tablet fragility, disintegration time, metoclopramide HCl levels. Physical quality test results were statistically analyzed to determine the effect of variations in the diluent on the characteristics of chewable tablets. The results of this research have an influence on the physical quality and uniformity of contents of various types of diluent variations between each formulation. In this research, fillers have an important role in the preparation of chewable metoclopramide tablets to determine the physical quality of the tablets and the uniformity of their contents. The variation of diluent that gives better results is mannitol. This is because formulas that use mannitol have uniformity in content that meets the requirements, faster disintegration time, and physical quality of tablets that still meet the requirements, when compared to the first and second formulations. The variation of diluent that gives better results is mannitol.
EFFECT OF VARIATION OF LUBRICANT CONCENTRATION (MAGNESIUM STEARATE) ON THE PHYSICAL QUALITY OF METOCLOPRAMID HCl TABLETS WITH DIRECT PRINTING METHOD Puspadina, Valiandri; Budi Legowo, Deny; Fitriany, Erna; Priyoherianto, Andri; Damayanti, Winda
Indonesian Journal of Pharmaceutical Education Vol 1, No 2 (2021): Mei-Agustus 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i2.10567

Abstract

Metoclopramide HCl is used to relieve nausea and vomiting. Market availability in the form of tablets, syrup and injection. The most preferred drug use by patients is oral medication because of its ease of use. Chewable tablets are a new product as an alternative for treatment in pediatric and adult patients who have difficulty swallowing drugs. This study aims to formulate the chewable tablet preparations of metoclopramide HCl using variations in lubricant concentrations. The variations of magnesium stearate with concentrations of 1%, 2%, and 3% using the direct printing method made to obtain a better physical quality test including organoleptics, weight uniformity, uniformity of size, tablet hardness, tablet brittleness, tablet crush time, uniformity of content. The results of the physical quality test were statistically analyzed using one way ANOVA to determine the effect of variations in the concentration of lubricants on the characteristics of chewable tablets. The results showed that variations in the concentration of magnesium stearate lubricant in the manufacture of metoclopramide HCl chewable tablets had an effect on the physical quality of metoclopramide HCl chewable tablets. The concentration of magnesium stearate which produces metoclopramide HCl chewable tablets with good physical properties is 2%.
Studi Pengaruh Karakteristik terhadap Pengetahuan Ibu Hamil di Rumah Sakit X, Sidoarjo tentang Keamanan Penggunaan Obat Prioheriyanto, Andri; Fitriany, Erna; Rizky Arif, M
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 3 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i3.8722

Abstract

Selama kehamilan, ibu hamil mengalami berbagai masalah kesehatan seperti nyeri pinggang, mual, dan muntah. Penggunaan berbagai jenis obat digunakan untuk meredakan masalah ini tanpa adanya konsultasi dengan tenaga medis. Efek samping yang merugikan akan timbul jika konsumsi obat dilakukan secara tidak tepat. Tujuan penelitian ini adalah melakukan evaluasi tingkat pengetahuan ibu hamil mengenai keamanan penggunaan obat dan menganalisis hubungan karakteristik demografis terhadap pengetahuan tersebut di Rumah Sakit X Sidoarjo. Metode penelitian yang digunakan adalah deskriptif non-eksperimental dengan teknik purposive sampling, melibatkan seluruh ibu hamil yang mengunjungi RS dan bersedia ikut serta dalam penelitian dengan menandatangani informed consent. Data dikumpulkan melalui kuesioner berbentuk checklist yang dinilai dengan skala Guttman. Hasil menunjukkan bahwa 81 % ibu hamil di Rumah Sakit X Sidoarjo  memiliki pengetahuan yang baik tentang penggunaan obat. Namun, analisis statistik menunjukkan tidak adanya hubungan signifikan antara tingkat pengetahuan dan variabel usia, usia kehamilan, serta riwayat pendidikan, dengan nilai p ≥ 0,05 untuk semua variabel tersebut. Ini menunjukkan bahwa faktor-faktor demografis tersebut tidak berpengaruh terhadap pengetahuan responden di sampel ini.
Formulasi Uji Mutu Fisik dan Uji Stabilitas Sediaan Lotion Ekstrak Daun Kamboja Putih (Plumeria acuminata) Ubaiddillah, Zidan; Fitriany, Erna; Suci, Panji Ratih; Safitri, Cikra Ikhda Nur Hamidah
Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) 2021: Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.596 KB)

Abstract

Tanaman daun kamboja putih (Plumeria acuminata) merupakan salah satu dari sekian banyak tanaman yang ada di Indonesia, tanaman daun kamboja putih ini termasuk tanaman yang memiliki kandungan alkaloid dan flavonoid. Metode penelitian ini bersifat eksperimental yang terdiri dari pembuatan simplisia dan pembuatan ekstrak dengan menggunakan metode maserasi dengan pelarut etanol 96%. Digunakan formulasi dengan konsentrasi 3%(formulasi 1),5%(formulasi 2),7%(formulasi 3) dan 0%(formulasi 0) sebagai kontrol basis. Evaluasi mutu fisik sediaan meliputi uji organoleptis, uji homogenitas, uji tipe emulsi dan uji stabilitas, penyimpanan selama 30 hari. Hasil dari penelitian ini lotion beraroma khas dari ekstrak sangat pekat, warna stabil hijau tua dan tidak ada perubahan warna selama 30 hari dengan penyimpanan suhu ruang dengan pH berkisar 6-7. Homogenitas dari lotion ini stabil dengan menunjukan adanya partikel padat, dan tipe emulsi W/O atau air dalam minyak. berdasarkan hasil penelitian ini didapat kesimpulan bahwa lotion stabil pada parameter homognitas, pH dan tipe emulsi tidak terdapat perbedaan mutu fisik sediaan lotion pada konsentrasi 3%,5%,7% yang disimpan pada suhu ruang.
Co-Authors Alfulaila Alfulaila Andri Priyoherianto Budi L, Deny Budi Legowo, Deny Cikra Ikhda Nur Hamidah Safitri Damayanti, Winda Deny Budi L Deny Budi L. Deny budi legowo Didik Andito Elly Purwati Fahmi Ardianti Purnawiranita fathul hidayatul Husna Indah Tri Lestari indah trilestari Iswandi Iswandi Iswandi Latifiana, Umi M. Rizky Arif Masfah Raudlotus S. Masfah Raudlotus Shofiyyah Novia Ariani Novianto Ainul Huri, Muhammad Nurfitriyawatie Nurfitriyawatie Panji Ratih Suci Panji Ratih Suci Panji Ratih Suci, Panji Ratih Prioheriyanto, Andri Puspadina, Valiandri Riski Ramadhan Rizky Arif, M safitri, cikra ikhda Nur Hamidah Supomo Ubaiddillah, Zidan Valiandri puspadina Zakiyatul Hamida Zuanta Pangestuti