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All Journal BALI MEDICAL JOURNAL (BMJ) E-Jurnal Medika Udayana PREMISE LAW JURNAL Berkala Ilmu Kesehatan Kulit dan Kelamin Universa Medicina ISM (Intisari Sains Medis) : Jurnal Kedokteran Bioscientia Medicina : Journal of Biomedicine and Translational Research Neurologico Spinale Medico Chirurgico Indian Journal of Forensic Medicine & Toxicology Bioscientia Medicina : Journal of Biomedicine and Translational Research Journal of Global Pharma Technology

I Gusti Ayu Agung Elis Indira

Bagian/SMF Ilmu Kesehatan Kulit Dan Kelamin, Fakultas Kedokteran Universitas Udayana

Author-ID : 588638

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health

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KORELASI FAKTOR PREDIPOSISI KEJADIAN SKABIES PADA ANAK- ANAK DI DESA SONGAN, KECAMATAN KINTAMANI, KABUPATEN BANGLI, PROVINSI BALI Pande Mirah Dwi Anggreni; I Gusti Ayu Agung Elis Indira
E-Jurnal Medika Udayana Vol 8 No 6 (2019): Vol 8 No 6 (2019): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (284.731 KB)

kabies adalah kelainan dermatologi yang diakibatkan infestasi dari Sarcoptes scabei,yang biasanya ditemukan di daerah pedesaan. Desa Songan merupakan suatu desa yang beradadi Kabupaten Bangli dengan tingkat insiden skabies yang tinggi khususnya di musim dingin.Padahal daerah di sekitar Desa Songan, kasus skabiesnya tergolong rendah. Penelitian skabiesini dimaksudkan untuk mengetahui faktor prediposisi terkait dengan fenomena skabies padaanak-anak sekolah dasar di Desa Songan. Studi dengan metode potong lintang ini dilaksanakandari bulan Maret hingga Oktober 2015. Sejumlah 178 anak dari dua sekolah dasar di DesaSongan menjadi subjek penelitian. Kejadian skabies beserta faktor prediposisi yangberhubungan dinilai melalui kuesioner dan wawancara. Data kemudian dianalisis dengan analisaunivariat dan bivariat. Dari 178 anak dalam penelitian ini, prevalensi skabies sejumlah 23,6%.Prevalensi pada anak laki-laki lebih besar dibanding anak perempuan (69,0% dan 31,0%).Mayoritas kasus skabies ditemukan pada anak dengan personal hygiene yang buruk (92,6%),status nutrisi yang buruk (85,7%), status ekonomi rendah (78,6%), tingkat pengetahuan orangtua pada skabies yang rendah (85,7%). Beberapa faktor yang ditemukan berhubungan secarasignifikan dengan kejadian skabies adalah jenis kelamin (p=0,004) dan personal hygiene(p=0,001). Kejadian skabies di Desa Songan secara signifikan dipengaruhi oleh faktor jeniskelamin dan personal hygiene. Program edukasi terkait personal hygiene dan kebersihanlingkungan dengan target anak-anak sekolah dasar sangat perlu dikembangkan. Determinansosial dan ekonomi yang mendasari lainnya yang berkontribusi terhadap kebersihan pribadiyang rendah juga perlu ditangani. Kata kunci : skabies, anak, faktor risiko, Desa Songan

ANALISIS YURIDIS PEMBATALAN PERDAMAIAN DALAM PENUNDAAN KEWAJIBAN PEMBAYARAN UTANG (PKPU) (Studi Kasus Putusan Nomor: 376K/Pdt.Sus-Pailit/2017 dan Putusan Nomor: 794K/Pdt.Sus-Pailit/2016) INDIRA MELISSA
PREMISE LAW JURNAL Vol 1 (2019): VOLUME 1 TAHUN 2019
Publisher : PREMISE LAW JURNAL

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Dosen Pembimbing:1. Prof. Dr. Sunarmi, SH, MHum2. Prof. Dr. Hasim Purba, SH, MHum3. Dr. Dedi Harianto, SH, MHum The research problems formulated based on this case are: 1) What factors can cause the annulment of reconciliation agreement in PKPU process, 2) How about the legal consequence for the debtor if the annulment of the reconciliation agreement is approved or objected, 3) What the basis of the judge’s consideration to settle and pronounce the case in Case No. 376K/Pdt.Sus-Pailit/2017 and Case No. 749K/Pdt-Sus-Pailit/2016. The research applies normative juridical method with descriptive analysis. Library research and field research are done to collect the data by conducting document study and guided interviews. The data are analyzed qualitatively and the conclusion is drwan deductively, from general to specific things. The results of the resaerch demonstrate that the application for an annulment of a reconciliation aggreement, that has been validated by the Judge and approved by creditor and debtor, can be either objected or accepted.Keywords: Reconciliation, Homologa tie, PKPU (Suspension of Debt Payment Obligation)

Alasan dan Motivasi Penghilangan Tato dengan Laser Q-Switch Nd-Yag, Teknik Kombinasi Laser: Kasus Seri Igusti Ayu Praharsini; IGAA Elis Indira
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 31 No. 2 (2019): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Latar Belakang: Tato merupakan seni dekorasi tubuh yang banyak digunakan dan sebaliknya banyak juga yang berkeinginan untuk menghilangkannya dengan berbagai alasan. Ada beberapa modalitas terapi menghilangkan tato. Laser Q-Switch (QS) merupakan prosedur standar baku untuk menghilangkan tato. Respon terapi menghilangkan tato dengan laser merupakan masalah dalam penatalaksanaanya, karena respon terapinya yang tidak dapat diprediksi. Tujuan: Untuk mengetahui alasan dan motivasi pasien menghilangkan tato dan respon terapi menggunakan laser. Kasus: Kasus 1, 2, dan 3 memiliki tato dekoratif warna hitam dengan lokasi punggung dan tangan yang dikerjakan oleh seorang tato amatir (kasus 1 dan 3) serta tato profesional pada kasus 2. Pada pasien ini dilakukan penghilangan tato menggunakan laser QS neodymium-doped yttrium aluminium garnet (Nd:YAG) 1064 nm, jumlah penyinaran 2-6 sesi dengan interval 4-6 minggu. Teknik kombinasi laser fractional Erbium-YAG 2940 nm, diikuti dengan laser QS Nd:YAG 1064 nm dilakukan pada kasus 3. Respon terapi kasus 1 dan 3 menunjukkan gambar tato memudar, sedangkan kasus 2 menunjukkan gambar tato sedikit memudar. Pembahasan: Tato dekoratif berwarna hitam dan tato amatir memerlukan jumlah sesi penyinaran lebih sedikit, rata-rata 4-10 sesi penyinaran. Teknik kombinasi laser merupakan inovasi baru untuk mempersingkat sesi penyinaran dengan hasil terapi yang maksimal. Simpulan: Untuk menghilangkan tato dengan laser diperlukan penilaian berbagai faktor yang berperan, sehingga hasil terapi dapat memberikan kepuasan pada pasien.

Lipschutz Ulcer in A Virgin Woman: A Case Report I Gusti Ayu Agung Elis Indira; Vanessa Vijayamurthy; Made Dwi Puspawati; Anak Agung Gde Putra Wiraguna
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 3 (2020): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.3.2020.244-249

Background: Lipschutz ulcer, also known as vulvae acutum ulcer, is an acute ulcer in the vulva. The aetiology and pathogenesis of Lipschutz ulcer are unclear, but it is known to be associated with infectious diseases such as Mycoplasma infection, paratyphoid fever, influenza A, and most infections with Epstein-Barr virus (EBV). This ulcer appears in adolescent females aged 14–20 years old, with 70% of cases occurring in virgin women. Purpose: To review the causes of non-Sexually Transmitted Diseases (STD) ulcers, so clinicians can establish an accurate diagnosis and rational therapy; therefore, minimizing the psychological impact on the patient due to possible misdiagnosis of STD-induced ulcer. Case: A painful wound in the genital area of a 20-year-old virgin woman. She was diagnosed with Lipshutz ulcer and vulvovaginal candidiasis based on the anamnesis, physical examination, and laboratory examination obtained from vaginal discharge using potassium hydroxide, Gram staining, and blood test to exclude genital ulcer caused by the sexually transmitted agent. A blood test was taken, including the serological tests for syphilis and genital herpes. Tests for EBV were also performed. The patient was treated only with single-dose fluconazole 150 mg orally and saline compress on the ulcer. Genital ulcer and vaginal discharge improved one week after treatment. Discussion: Lipshutz ulcer management is symptomatic, usually self-limiting, and disappears spontaneously within 1–2 weeks without recurrences. It can also occur as a single lesion with possible coinfection of other agents, for example, candidiasis, which in this case, requires treatment of comorbidities. Hygiene factors play an essential role in preventing occurrence of the secondary infection and further development of the disease. Conclusion: The diagnosis of Lipshutz ulcer is mainly based on clinical manifestation after excluding several possible ulcers that can affect the genital area, including sexually transmitted infections.

Prevalence of occupational contact dermatitis in cleaning service in the Sudirman campus of Udayana University Jihan Prani Wibowo; Nyoman Suryawati; I Gusti Agung Ayu Elis Indira; I Gusti Agung Ayu Praharsini
Neurologico Spinale Medico Chirurgico Vol 3 No 2 (2020)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36444/nsmc.v3i2.117

Introduction: Occupational contact dermatitis is contact dermatitis caused by work-related exposures. While doing their work, cleaning service workers are facing various risks of occupational diseases, one of which is occupational contact dermatitis. The purpose of this study is to determine the prevalence and characteristics of occupational contact dermatitis in cleaning service workers at the Sudirman Campus of Udayana University.Methods: This research is a descriptive study using a cross-sectional method and uses 47 samples. Results: The prevalence of occupational contact dermatitis in cleaning services in Sudirman Campus of Udayana University is 10.6%, with the characteristics of age mostly found in 21 – 30 years (9.5%) and 31 – 40 years (18.2%), dominated by men (16.7%), working period <4 years (12.5%), duration of contact ≥3 hours (14.3%), without a history of allergies (10%), with a history of disease other skin (23.5%), good personal hygiene (7.5%), and using Personal Protective Equipment (7.3%). The dominant chemical that is used is acid (11.1%) though workers can contact more than one type of substance. The most common symptoms complained of include itching, burning or burning, redness of the skin, and peeling skin. Conclusion: The prevalence of occupational contact dermatitis in cleaning service workers at Sudirman Campus of Udayana University is 10.6% and the factors contributing are the duration of contact, gender, age, contact with chemicals, years of service, history of allergies, history of other skin diseases, personal hygiene, and the use of personal protective equipment.

Karakteristik kanker kulit di Rumah Sakit Umum Pusat Sanglah Denpasar tahun 2015-2018 Made Wardhana; I Gusti Nyoman Darmaputra; I Gde Nengah Adhilaksman; Nyoman Yoga Maya Pramita; Ricky Fernando Maharis; Made Dwi Puspawati; I Gusti Ayu Agung Dwi Karmila; I Gusti Agung Ayu Praharsini; I Gusti Ayu Agung Elis Indira; Nyoman Suryawati
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Latar belakang: Prevalesi kanker kulit semakin meningkat di seluruh dunia. Walaupun insiden tertinggi pada kelompok berkulit putih, namun mengetahui epidemiologi dan tren penyakit dari kanker kulit diperlukan agar dapat menentukan pencegahan dan penanganan yang tepat.Tujuan: Untuk mengetahui karakteristik kanker kulit pada pasien yang telah dilakukan skin flap di Departemen Dermatologi dan Venereologi RSUP Sanglah.Metode: Penelitian ini merupakan studi deskriptif retrospektif dari catatan medis semua penderita kanker kulit yang memperoleh tindakan skin flap sejak Januari 2015 sampai dengan Desember 2019. Sampel diambil melalui total sampling. Karakteristik yang tercatat meliputi jenis kanker, jenis kelamin, umur, tipe kulit, pekerjaan, dan jenis flap yang dilakukan. Data yang terkumpul dianalisis secara deskriptif dengan program SPSS Ver21.Hasil: Terdapat 41 pasien kanker kulit yang memperoleh tindakan skin flap, terdiri dari 43,9% (n=16) BCC, 54,6% (n=10) melanoma, 21,9% (n=9) SCC, 9,8% (n=4) jenis kanker lain. Jenis flap yang umum digunakan yaitu simple advancement. Lokasi kanker paling umum ditemukan pada wajah dan kejadian kanker paling tinggi terjadi pada usia â‰¥50 tahun dan bekerja di luar ruangan.Simpulan: Kasus kanker tertinggi yaitu BCC dengan usia lebih dari 50 tahun dan bekerja di luar ruangan sebagai karakteristik paling umum pada semua kasus kanker.

Karsinoma sel basal tipe nodular yang diterapi dengan bedah eksisi elips dan anastesi tumesen I Gusti Nyoman Darmaputra; Made Wardhana; I Gde Nengah Adhilaksman; I Gusti Ayu Agung Elis Indira; Nyoman Suryawati
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Background: Basal cell carcinoma (BCC) has a very slow-growing and rarely metastatic nature but tends to be locally invasive and relapse after therapy. Elliptical excision is one of the surgical procedures in the field of dermatology which is most often used with the application of tumescent techniques.Case Description: A woman, 64 years old, no. CM. 18.03.11.71, Balinese tribe, on July 30, 2018, came to the Dermatology and Venerology Polyclinic at Sanglah General Hospital with a frequent symptom of arising from wounds on the forehead. The lession began one year ago. Initially, it was a small reddish lump which was then felt more and more dilated as well as became blackish and accompanied by itching. Dermatology examination revealed hyperpigmentation, solitary, oval, 3x2cm, multiple erosion, firm boundary, round shape, 0.3-0.4 cm in diameter, covered in black crusting on top.Conclusion: The diagnosis of BCC determined on anamnesis, physical examination, dermoscopy, and histopathology regard with standard ellipse excision surgery.

Disregulasi IL-17, CD4 neutrofil, IL-10, PGE-2, iNOS, dan MMP-9 di jaringan kulit terhadap kerusakan saraf dermal pada pasien erythema nodusum leprosum I Gusti Nyoman Darmaputra; Cita Rosita Sigit Prakoeswa; Anang Endaryanto; IGAA Elis Indira; Nyoman Suryawati; Evy Ervianti; Linda Astari; Bagus Bagus
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: The mechanism of nerve damage in ENL patients is important to be revealed because the problem of nerve damage is not getting enough attention in handling ENL patients. Some pro-inflammatory mediators that have been studied are risk factors for nerve damage in ENL.Aim: This study aim in knowing the mechanism of nerve damage in the relation with its risk factors, which are CD64 neutrophil, IL-17, MMP-9, and iNOS with PGE-2 and IL-10 protective factor and IL-10 in ENL patients.Method: This is an analytic cross-sectional design study with tissue samples from 30 leprosy patients with ENL in Dr. Soetomo General Hospital Surabaya. Samples from biopsy examined using IHC method to evaluate S-100, IL-10, IL-17, PGE-2, iNOS, MMP-9, and CD64 neutrophil expressions. The result calculated within 20 view field with 1000 times magnification.Result: CD64 neutrophil (p=0.022, r=-0.417), IL-17 (p=0.001, r=-0.560), iNOS (p=0.005, r=-0.502) and MMP-9 (p=0.025, r=-0.409) has significant correlation with S-100. There is no significant correlation between IL-10 (p=0.061) and PGE-2 (p=0.407) with S-100.Conclusion: Expressions of IL-17, CD64 neutrophil, MMP-9, and iNOS in tissue correlate with nerve damage in ENL patients.

Prevalence and clinical manifestations of patients with psoriasis in RSUP Sanglah from 2017 to 2018 Daarshawnee Segar; IGAA Praharsini; IGAA Elis Indira
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Background: Psoriasis is a complex, multifactorial, inflammatory, chronic autoimmune disorder that changes the life cycle of skin cells. In countries around the world, the prevalence of psoriasis ranges from 0.09% to 11.43%.Objective: This study aims to determine the prevalence and clinical manifestations of patients with psoriasis in RSUP Sanglah Denpasar from the year 2017 to 2018.Method: The study used is a descriptive retrospective study design using total sampling with142 samples recorded.Results: The prevalence of psoriasis was 0.603% in 2017 and 0.708% in 2018. Between 2017 till 2018, a total of 142 patients reported having psoriasis with 73 patients (51.4%) in 2017 and 69 patients (48.6%) in 2018. The cases were dominated by males with 90 patients (63.4%) and females with 52 (36.6%) for both the years. Psoriasis patients between the ages of 36-45 years were reported the most with a proportion of 23.2%. The least number of patients were reported below the age of 5 years. There was a total of 63(44.4%) patients diagnosed with psoriasis vulgaris which is also the most common type of psoriasis case found in Sanglah. The least number of patients were psoriasis inverse and erythrodermic with 4(2.8%) patients each.Conclusion: The clinical manifestations used to diagnose psoriasis were red sharp boundaries erythematous plaque, covered with silver or scaly white squamae and geographic skin lesion. This clinical finding was used for almost all psoriasis diagnosis.

Peran sirkumsisi sebagai pencegahan infeksi herpes genetalis: suatu studi kohort retrospektif Made Wardhana; Martina Windari; Marrietta Sugiarti Sadeli; Anak Agung Gde Putra Wiraguna; Ni Made Dwi Puspawati; I Gusti Ayu Agung Elis Indira; Pande Agung Mahariski
Intisari Sains Medis Vol. 12 No. 2 (2021): (Available Online: 1 August 2021)
Publisher : DiscoverSys Inc.

Background: Recurrent genital herpes (RGH) is a sexually transmitted infection that is a serious public health problem and is quite prominent in most countries worldwide. Management for this infection is antiviral and circumcision. Male circumcision significantly reduces human immunodeficiency virus (HIV) infection and other sexually transmitted infections. This research aims to evaluate circumcision efficacy as the prevention for herpes simplex virus type 2 (HSV-2) infection compared with oral acyclovir.Methods: This research is an experimental study with a retrospective cohort approach. We included 45 males, 24 subjects circumcised and 21 subjects without circumcision and took oral acyclovir as standard treatment. RGH was diagnosed based on typical clinical manifestation. Follow up treatment every two weeks and continued to 2 months after circumcised and given with oral acyclovir. Successful treatment was stated without recurrent genital herpes.Results: Of 24 circumcised subjects, 19 were cured, and five non-circumcised subjects suffered recurrent genital herpes (not cured). Among 21 subjects without circumcision was cured, and 12 subjects were not cured. Based on these results, the value of NNT= 2.7.Conclusion: Circumcision can be considered effective in reducing the incidence of HGR and prevent recurrence of HGR with the NNT value of 2.7. Latar Belakang: Herpes genetalis rekuren (HGR) merupakan infeksi menular seksual menjadi masalah kesehatan masyarakat yang serius dan cukup menonjol pada sebagian besar negara di dunia. Penanganannya adalah oral dengan antivirus dan tindakan sirkumsisi. Sirkumsisi pada pria secara signifikan mengurangi insiden infeksi human immunodeficiency virus (HIV) dan penyakit infeksi menular lainnya. Penelitian ini mengevaluasi efikasi sirkumsisi sebagai pencegahan infeksi virus herpes simpleks tipe 2 (HSV-2) dibandingkan dengan pemberian obat asiklovir.Metode: Studi ekperimental dengan pendekatan retrospektif kohort dengan mengikutsertakan 45 subjek pria dewasa, 24 subjek disirkumsisi dan 21 tanpa sirkumsisi dan hanya diberikan asiklovir sebagai obat standar. Diagnosis HGR dilakukan secara klinis dengan yang manifestasi klinis yang khas da pemeriksaan Tzanck. Setelah pemberian terapi dilakukan kontrol setiap 2 minggu sampai 2 bulan. Terapi dinyatakan berhasil bila tidak ada kekambuhan.Hasil: Dari 24 subjek disirkumsisi, 19 subjek dinyatakan sembuh dan 5 subjek mengalami kekambuhan (tidak sembuh). Dari 21 subjek tanpa sirkumsisi, 9 subjek dinyatakan sembuh dan 12 subjek dinyatakan tidak sembuh. Berdasarkan hasil ini didapatkan nilai NNT=2,7.Simpulan: Sirkumsisi dapat dinilai cukup efektif mengurangi angka kejadian HGR dan dapat mencegah kekambuhan HGR dengan nilai NNT 2.7.

Co-Authors Adelia Suryani Aditya Permana Aditya Permana Anak Agung Gde Putra Wiraguna Anang Endaryanto Andrew Wicaksono Aurelia Stephanie Bagus Bagus Cita Rosita Sigit Prakoeswa Daarshawnee Segar Dewa Ayu Agung Dwita Arthaningsih Dwi Puspawati, Ni Made Evy Ervianti Febrina D Pratiwi Firly Clarissa Suyanto Herman Saputra Hermina Laksmi I Dewa Made Rendy Sanjaya I Gde Nengah Adhilaksman I Gde Nengah Adhilaksman I Gusti Ayu Agung Dwi Karmila I Gusti Ayu Agung Praharsini I Gusti Nyoman Darmaputra I Ketut Agus Somia Ida Bagus Nyoman Putra Dwija Ivana Sugiarto Jihan Prani Wibowo Joanne Roxanne Jordaniel Setiabudi Ketut Kwartantaya Winaya Ketut Tuti Parwati Merati Ketut Wida Komalasari Komang Agus Trisna Amijaya, Komang Agus Trisna Linda Astari, Linda Luh Made Mas Rusyati Luh Putu Arya Putri Ratnasari Made Dalika Nareswari Made Puspawati Made Swastika Adiguna Made Wardhana Made Yogi Oktavian Prasetia Made Yogi Oktavian Prasetia, Made Yogi Oktavian Marrietta Sugiarti Sadeli Martina Windari Michael Hostiadi Nevristia Pratama Ni Luh Putu Ratih Vibriyanti Karna Ni Made Dewi Dian Sukmawati Ni Made Dwi Puspawati Ni Made Sruti Mahaswari Soethama Ni Putu Wina Widyastuti Ni Wayan Evita Pradnya Dharmesti Ni Wayan Winarti Nila Wardani Nittaya Phanuphak, Nittaya Nyoman Suryawati Nyoman Yoga Maya Pramita Pande Agung Mahariski Pande Mirah Dwi Anggreni Putu Setiani Ricky Fernando Maharis Riyana Noor Oktaviyanti Sawitri, Anak Agung Sagung Vanessa Vijayamurthy Wiraguna, Swastika Adiguna Wisnu Triadi Nugroho Yundari, Yundari

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