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All Journal BALI MEDICAL JOURNAL (BMJ) Jurnal Ergonomi Indonesia (The Indonesian Journal of Ergonomic) E-Jurnal Medika Udayana Media Kesehatan Masyarakat Indonesia Indonesian Journal of Tropical and Infectious Disease WMJ (Warmadewa Medical Journal) Bali Anatomy Journal CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Warmadewa Minesterium Medical Journal INDONESIAN JOURNAL OF URBAN AND ENVIRONMENTAL TECHNOLOGY The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Biomedika
Cokorda Agung Wahyu Purnamasidhi
Tropical And Infectious Diseases Division, Internal Medicine Department, Universitas Udayana, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Earth & Planetary Sciences Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Medicine & Pharmacology Public Health

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Epidemiological, Clinical, And Occupational Characteristics of Migrant Workers Confirmed with COVID-19 At Udayana University Hospital Paramita, Ni Putu Pradnya; Wirawan, I Made Ady; Purnamasidhi, Cokorda Agung Wahyu; Florensia, Maria; Akatsu, Haruko
Indonesian Journal of Tropical and Infectious Disease Vol. 12 No. 2 (2024)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v12i2.44596

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has prompted Indonesian expatriates to return home. Travel history, including migrant repatriation, was thought to spread COVID-19. These factors increased COVID-19 transmission. This study examined the epidemiological, clinical, and occupational characteristics of migrant workers with COVID-19 at Udayana University Hospital. This descriptive study utilized a cross-sectional methodology. The research samples consisted of 97 migrant workers diagnosed with COVID-19 who had been treated at Udayana University Hospital between March to August of 2020, using the total sampling technique. The median age (IQR) of migrant workers is 30, and 84.53% are male. Before returning to Indonesia, many worked and visited the US (20.6%). 87.63% of respondents worked in hospitality sector, and mostly worked in 8–12-hour shifts. All respondents have insurance; most employers are provided with PPE and information regarding COVID-19 prevention. At the airport, COVID-19 screening revealed fever (70.6%) and cough (76.3%) as the most common symptoms. A 94.8% of migrant workers had no comorbidities, and 87.6% had normal chest X-rays. From this research, we discovered that amongst migrant workers, positive-COVID-19 results were mostly found in young, mobile men. Most of them worked for 8–12 hours per day, and majority worked in hospitality sector. Almost all of them did not have any comorbidities and the most common symptoms found were fever and cough. The findings suggest that male workers in their productive age with high mobility and working in the hospitality sector are at higher risk of infection. 
Occupational and Return-To-Work Characteristics of Covid-19 Patients After Treated in Udayana University Hospital Karya, I Kadek Jony Dwi; Wirawan, I Made Ady; Purnamasidhi, Cokorda Agung Wahyu; Florensia, Maria; Akatsu, Haruko
Indonesian Journal of Tropical and Infectious Disease Vol. 12 No. 1 (2024)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v12i1.45414

Abstract

Corona virus disease 2019 (COVID-19) is a new disease caused by severe acute respiratory syndrome corona virus 2 (SARS-COV-2). The COVID-19's symptoms are fatigue, muscle pain, and psychological disorders. The purpose of this study was to describe the occupational characteristics and health conditions of COVID-19 patients who had recovered after being treated at Udayana University Hospital. This study is a descriptive study with a quantitative method and cross-sectional design. The research samples were 110 COVID-19 patients treated at Udayana University Hospital from June to August 2020 and taken using random sampling. The results showed that the highest proportion of respondents were aged between 24-44 years (44.5%), with almost equal proportions of women (50.1%) and men (49.09%). Most of them lived in Denpasar (46.36%). Most respondents work as private sector employees (24.55%), and 70% of them were using personal protective equipment (PPE) while working. Most respondents needed less than seven days to return to work after being declared "in recovery state” (60%), with the remaining 55.5% having a decreased work duration to be less than 8 hours per day. The proportion of respondents with comorbidities was 30.91%. As many as 27.27% were experiencing previously similar symptoms (fever, fatigue, cough) 4 to 5 months after being declared "cured.” COVID-19 patients who have recovered should be monitored for a longer period of time to evaluate the symptom reoccurrence and its impact on their occupational and health conditions.
Comorbid Diseases and Outcomes of Critically Ill COVID-19 Patients Admitted to an Indonesian Intensive Care Unit from May to October 2021 Siahaan, Katrin Wilentina; Somia, I Ketut Agus; Utama, I Made Susila; Dian, Ni Made Dewi; Gayatri, Anak Agung Ayu Yuli; Purnamasidhi, Cokorda Agung Wahyu; Merati, Ketut Tuti Parwati
Current Internal Medicine Research and Practice Surabaya Journal Vol. 5 No. 2 (2024): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v5i2.54859

Abstract

Introduction: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2). The spread of COVID-19 has become a worldwide health threat, with 583,038,110 cases and a death toll of 6,416,023. This study attempted to determine the relationship of age, sex, and comorbid diseases with the outcomes of critically ill COVID-19 patients at Prof. Dr. IGNG Ngoerah Central General Hospital, Denpasar, Indonesia. Methods: This analytic study employed a retrospective approach, analyzing secondary data from medical records using a purposive sampling method. The research included univariate analysis, bivariate analysis using the chi-square test, and multivariate analysis using a general linear model performed with the assistance of IBM SPSS Statistics for Windows, version 23.0 (IBM Corp., Armonk, N.Y., USA). A statistical analysis result with a p-value of less than 0.05 was deemed significant. Results: A total of 264 critically ill COVID-19 patients were hospitalized in the Intensive Care Unit of Prof. Dr. IGNG Ngoerah Central General Hospital from May to October 2021. Comorbid diseases were present in 215 patients. The comorbid diseases that had the greatest impact on increasing mortality were diabetes mellitus, hypertension, kidney disease, and cardiovascular disease (p=0.000–0.006, 95% CI). Conclusion: Age and sex do not have any significant relationship with the outcomes of critically ill COVID-19 patients. Meanwhile, comorbid diseases, such as diabetes mellitus, hypertension, and renal and cardiovascular diseases, pose a significant impact on the mortality rate of critically ill COVID-19 patients.   Highlights: 1. This study investigated patients who were critically ill with COVID-19 to determine the relationship between age, sex, comorbidities, and patient outcomes. 2. The findings of this study may provide additional data on the impact of comorbidities on the severity of COVID-19, which can be valuable to prevent mortality due to the infection.
Beban Tas Siswa di Sekolah Dasar Saraswati 5 Denpasar Harkitasari, Saktivi; Dewi Manuaba, Ida Ayu Laxmi Ananda; Primayanti, I Dewa Ayu Inten Dwi; Purnamasidhi, Cokorda Agung Wahyu
Jurnal Ergonomi Indonesia (The Indonesian Journal of Ergonomic) Vol 6 No 2 (2020): Volume 6 No 2 Desember 2020
Publisher : Program Studi Magister Ergonomi Fisiologi Kerja Pascasarjana Universitas Udayana Denpasar Bekerjasama dengan Perhimpunan Ergonomi Indonesia (PEI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JEI.2020.v06.i02.p09

Abstract

The use of school bags without ergonomics design, miscarriage school bag, excessive bag load and carrying bags with long duration could be risk of disrupting the musculoskeletal system. The aim of this research is to know the frequency of bag load category of elementary students at SD Saraswati 5 Denpasar according to class, age, gender and weight of respondent. This research method was a descriptive cross-sectional study conducted at SD Saraswati 5 Denpasar. The sample in this study was selected by systematic random sampling. There were 86 respondents who carried load of bag of medium category amounted to 40 (46.5%) student, heavy bag category tend to carried by grade 3 student amounted to 12 (54.5%), male and female students carried the same bag load that is the moderate category 40 (46.5%) and the group with the mildest weight among other groups tend to carried heavy bag category amounted to 16 (55.2%). The conclusion is Students of Elementary School Saraswati 5 Denpasar more often carry the bag burden of the medium category. More heavy bag load categories are carried by students aged 7 years - 9 years. Groups of students with the lightest weight tend to carry heavy bag loads.
Pengabdian kepada Masyarakat dalam Upaya Pemanfaatan Ubi Ungu untuk Kesehatan Hidup Sehari-hari Jawi, I Made; Sutirta Yasa, I Wayan Putu; Purnamasidhi, Cokorda Agung Wahyu; Pujawan, I Made Naris; Suardika, Anom; Tirtha Yasa, I Nyoman Wawan; Pratiwi, Cokorda Agung; Divasta, I G Mahapraja
Warmadewa Minesterium Medical Journal Vol. 3 No. 3 (2024): September 2024
Publisher : Warmadewa University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstrak Penelitian tentang umbi ubi jalar ungu memiliki khasiat terhadap kesehatan melalui tingginya kadar antioksidan, antikarsinogenik, dan antiinflamasi. Kandungan antosianin yang cukup tinggi menjadi kunci utamanya. Oleh karenanya, antioksidan yang terkandung di umbi ubi jalar ungu tersebut sangat bermanfaat mencegah penyakit degeneratif. Seiring berjalannya waktu, kesadaran masyarakat mengenai pentingnya hidup sehat mulai meningkat. Solusi yang diterapkan untuk mengatasi permasalahan ini adalah melalui program pengabdian terkait pemanfaatan ubi ungu untuk mencegah penyakit degeneratif pada lansia. Program ini menargetkan 60 masyarakat karang lansia di Desa Celuk, dengan tujuan meningkatkan pengetahuan mereka terkait zat yang terkandung di dalam ubi ungu, cara pengolahan ubi ungu, dan manfaat kesehatan yang diperoleh dari ubi ungu. Metode pelaksanaan kegiatan ini dikemas menarik dengan hiburan, praktek pembuatan jus ubi ungu, sesi diskusi interaktif, dan evaluasi melalui pre-test dan post-test untuk mengukur efektivitas program. Hasil dari program ini menunjukan peningkatan signifikan dalam pengetahuan masyarakat mengenai manfaat dan khasiat ubi ungu untuk kesehatan hidup sehari-hari, dengan rata-rata peningkatan yang didukung oleh hasil uji statistik. Dengan demikian, pengabdian kepada masyarakat dalam upaya pemanfaatan ubi ungu untuk kesehatan hidup sehari-hari dapat meningkatkan kesadaran masyarakat karang lansia terkait pentingnya menjaga kesehatan di usia tua. Diperlukan perluasan cakupan program pengabdian ini ke wilayah-wilayah lain dan mengintegrasikan evaluasi jangka panjang untuk memastikan keberlanjutan kesadaran masyarakat dan perubahan perilaku yang diharapkan. Kata Kunci: Desa Celuk, Lansia, Pengabdian masyarakat, Ubi Ungu Abstract Community Service in an Effort to Utilise Purple Sweet Potato for Daily Living Health Research shows that purple sweet potato tubers have health benefits through high levels of antioxidants, anticarcinogenic, and anti-inflammatory substances. The high anthocyanin content is the main key. Therefore, the antioxidants contained in purple sweet potato tubers are very useful in preventing degenerative diseases. As time goes by, public awareness of the importance of healthy living begins to increase. The solution implemented to overcome this problem is through a community service program related to the use of purple sweet potatoes to prevent degenerative diseases in the elderly. This program targets 60 elderly communities in Celuk Village, with the aim of increasing their knowledge regarding the substances contained in purple sweet potatoes, how to process purple sweet potatoes, and the health benefits obtained from purple sweet potatoes. The method of implementing this activity is packaged attractively with entertainment, practice of making purple sweet potato juice, interactive discussion sessions, and evaluation through pre-test and post-test to measure the effectiveness of the program. The results of this program show a significant increase in public knowledge regarding the benefits and properties of purple sweet potatoes for daily health, with an average increase supported by statistical test results. Thus, community service in efforts to utilize purple sweet potatoes for daily health can increase awareness of the elderly community regarding the importance of maintaining health in old age. It is necessary to expand the scope of this service program to other areas and integrate long-term evaluation to ensure continued community awareness and expected behavioral changes. Keywords: Celuk Village, Elderly Population, Community Service, Purple Sweet Potato.
External Validation of AI-powered GeNose C19 to Diagnose Volatile Organic Compounds in COVID-19 Patients Tested at Udayana University Academic Hospital Purnamasidhi, Cokorda Agung Wahyu; Darwinata, Agus Eka; Utama, I Made Susila; Merati, Ketut Tuti Parwati; Harkitasari, Saktivi; Junior, Darren; Diksha, I Gusti Ngurah Ariestha Satya; Suteja, Richard Christian
Biomedika Vol 16, No 2 (2024): Biomedika Agustus 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v16i2.3940

Abstract

In search for potential alternatives to RT-PCR, Gadjah Mada University developed GeNose C19 which was deemed to have high sensitivity, specificity, PPV, and NPV. The objective of this study is to contribute to the development of GeNose C19 by means of external validation conducted in Udayana University Academic Hospital, Bali. This was a cross-sectional study conducted on adults above 17 years old. Demographic variables, symptoms, vaccination status, GeNose C19 results, and RT-PCR results were measured. We analyzed the sensitivity, specificity, PPV, and NPV using respective appropriate formulas and the impact of other variables gathered towards accuracy by means of Chi-squared test, Mann-Whitney U test and independent-samples T test. The results showed that the subjects included in this study were 50.8% female and had a mean (IQR) age of 23.0 (21.0-27.5) years old. Only three subjects (2.5%) showed COVID-19-related symptoms such as cough (1.7%), flu (0.8%), fever (0.8%), and headache (0.8%). GeNose C19 yields a sensitivity of 83.1%, a specificity of 73.6%, PPV of 79.4%, and NPV of 78.0%. There were no variables that significantly affect the accuracy of GeNose C19. Further study is still required to validate GeNose C19’s performance in different environmental conditions and multiple different races.
UNDERSTANDING LEVEL OF PKK BANJAR PURWA SANTHI BENOA ON MEDICAL MASK WASTE MANAGEMENT AND STRENGTHENING HEALTH PROTOCOLS IN CONTROLLING COVID-19 INFECTION Adiputra, I Komang Hotra; Harmayani, Kadek Diana; Susilawathi, Ni Made; Purnamasidhi, Cokorda Agung Wahyu; Witarini, Komang Ayu; Biantara, I Wayan Arya; Sukrama, I Dewa Made; Weisnawa, I Gede Purna; Jerry; Wulandari, Putu Kintan; Junior, Darren; Shanti, Dewa Ayu Fony Prema; Warmadewanthi, I Dewa Ayu Agung
INDONESIAN JOURNAL OF URBAN AND ENVIRONMENTAL TECHNOLOGY VOLUME 6, NUMBER 1, APRIL 2023
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/urbanenvirotech.v6i1.15335

Abstract

The increase in mask waste and a lack of understanding about the management of single-use mask waste raises the potential for environmental pollution and COVID-19 transmission. Aim: This study aimed to assess the level of understanding of medical mask waste management and strengthening health protocols in controlling COVID-19 infection in Banjar Purwa Santhi, Benoa, Badung Regency. Methodology and Results: A cross-sectional method and descriptive study design were used with a sample of 100 respondents selected via stratified sampling. The research and service activities at Banjar Purwa Santhi Benoa include public campaign and assessment of the level understanding of medical mask waste management. Based on univariate analysis, 91% of respondents know that mask waste contains hazardous and toxic substances. If mask waste is disposed carelessly, 98% of respondents stated that it can pollute the environment, and 98% of respondents also stated that it has the potential to become a means of transmitting COVID-19. However, 85% of respondents disposed of the masks in the household trash. Conclusion, significance and impact study: Respondents had a good level of knowledge about health protocols and mask waste management but have not separated masks from household waste. By holding the community service activity, it is hoped that changes in community behavior will occur.
Genetic Mutations and Polymorphisms Related to Severity, Mortality, and Antibody-Dependent Enhancement of Dengue Virus (DENV) Infection: A Literature Review Purnamasidhi, Cokorda Agung Wahyu; Junior, Darren; Satya Diksha, I Gusti Ngurah Ariestha; Hiranandini Prawista, I Gusti Ayu Maha; Guptha, I Dewa Gede Agung Siwa; Pratyaksa, I Gusti Ngurah Dinda; Indratmo, Novea; Suteja, Richard Christian; Harkitasari, Saktivi
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 3 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i3.70457

Abstract

The dengue virus (DENV) is a blood-borne Flavivirus transmitted through vectors and ranks as the fastest-spreading tropical disease globally. Dengue infection could exhibit mild to severe symptoms depending on various factors. Antibody-dependent enhancement (ADE) is a cross-reactive phenomenon between different DENV strains that clinicians should be aware of, as it leads to a higher incidence of dengue with warning signs and severe dengue. On the molecular level, many genes contribute to the severity and pathophysiology of ADE. Mutations and polymorphisms in these genes could alter the course of dengue infection. This article aims to comprehensively review studies that measure the impact of dengue-related genetic mutations and polymorphisms on the severity, mortality, and ADE of DENV infection. We performed a literature review to identify relevant articles on PubMed, Science Direct, Europe PMC, and Google Scholar. The review examines polymorphisms across multiple gene families: Fcγ receptors, cytokines (TNF-α, TGF-β1, IL-10), immune regulatory genes (MICB, PLCE1, RIPK2), antigen-presenting machinery (DC-SIGN, TAP), and host defense mechanisms (VDR, CTLA-4, MBL, HPA). These genetic variations have population-specific effects and may confer both protection in some populations and increased susceptibility to severe outcomes of dengue in others. The effects of these polymorphisms are context-dependent and differ according to the phase of infection, ethnicity, and gene-gene interactions. Overall, it could be concluded that aside from external factors, polymorphisms on human genes regulating mechanisms and components related to dengue infection have been extensively discussed to play a role in the overall clinical outcome.
Co-Authors Adiputra, I Komang Hotra Agus Eka Darwinata Akatsu, Haruko Anak Agung Ayu Yuli Gayatri Anom Suardika Biantara, I Wayan Arya Darren Junior Dewa Ayu Fony Prema Shanti Dewi Manuaba, Ida Ayu Laxmi Ananda Dian, Ni Made Dewi Diksha, I Gusti Ngurah Ariestha Satya Divasta, I G Mahapraja Florensia, Maria Gayatri, Anak Agung Ayu Yuli Giovanca Verentzia Purnama Guptha, I Dewa Gede Agung Siwa Haruko Akatsu Hiranandini Prawista, I Gusti Ayu Maha I Dewa Ayu Agung Warmadewanthi I Dewa Ayu Inten Dwi Primayanti, I Dewa Ayu Inten Dwi I Dewa Made Sukrama I Dewa Nyoman Wibawa I Gde Haryo Ganesha I Gede Purna Weisnawa I Kadek Swastika I Ketut Agus Somia I Ketut Mariadi I Komang Hotra Adiputra I Komang Hotra Adiputra I Made Ady Wirawan I Made Jawi I Made Sudarmaja I Made Susila Utama I Nyoman Gede Narendra Yanakusuma I Wayan Arya Biantara I Wayan Putu Sutirta Yasa I.D.A.A Warmadewanthi Indratmo, Novea Jerry Jerry Junior, Darren Kadek Diana Harmayani Karya, I Kadek Jony Dwi Ketut Tuti Parwati Merati Komang Ayu Witarini Krisnawardani K, Cokorde Istri Yuliandari Ni Luh Putu Eka Diarthini, Ni Luh Putu Eka Ni Made Dewi Dian Sukmawati Ni Made Susilawathi Paramita, Ni Putu Pradnya Pratiwi, Cokorda Agung Pratyaksa, I Gusti Ngurah Dinda Pujawan, I Made Naris Purnama, Giovanca Verentzia Putu Kintan Wulandari R. A.T. Kuswardhani Richard Christian Suteja Saktivi Harkitasari, Saktivi Satya Diksha, I Gusti Ngurah Ariestha Shanti, Dewa Ayu Fony Prema Siahaan, Katrin Wilentina Suastika, Luh Oliva Saraswati Susilawathi, Ni Made Suteja, Richard Christian Tirtha Yasa, I Nyoman Wawan Utama, I Made Susila Weisnawa, I Gede Purna Wulandari, Putu Kintan Yenny Kandarini