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All Journal Jurnal Ilmiah Farmasi Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Scholaria: Jurnal Pendidikan dan Kebudayaan Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Journal of Pharmaceutical Care Anwar Medika Academia Open Journal of Community Practice and Social Welfare (JaCiPS) Indonesian Community Journal Sainsbertek Jurnal Ilmiah Sains & Teknologi Abdimas Indonesian Journal Prosiding Seminar Nasional Universitas Ma Chung Jurnal Kesehatan dr. Soebandi Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas KOPEMAS Khidmat: Journal Community Service
Godeliva Adriani Hendra
Universitas Ma Chung
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Antibiotics and Antivirals in COVID-19: Clinical Outcomes Godeliva Adriani Hendra; Monika Turnip; FX. Haryanto Susanto
Academia Open Vol 8 No 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.8.2023.6662

Abstract

The clinical manifestations of COVID-19 disease are mainly caused by an irregular host response associated with excessive expression of inflammatory markers. Patients with mild, moderate, and severe symptoms of COVID-19 with or without comorbidities use a combination of antiviral drugs and antibiotics. This study aimed to determine the relationship between the use of antiviral drugs and antibiotics on the clinical outcomes of COVID-19 patients. The research design used a cross-sectional study with retrospective data collection. The inclusion criteria were COVID-19 patients hospitalized at Panti Waluya Sawahan Malang Hospital with or without comorbidities, positive RT-PCR results, and receiving antibiotic and antiviral therapy. The clinical outcome is a patient improvement if the length of stay is 14 days, and the patient worsens if it is >14 days. There is no relationship between antibiotics and antiviral drugs on the clinical outcomes of COVID-19 patients (p>0,05). Highlights: Excessive expression of inflammatory markers contributes to the clinical manifestations of COVID-19. Combination therapy of antiviral drugs and antibiotics is commonly used for COVID-19 patients. The study found no significant relationship between the use of antibiotics and antiviral drugs and the clinical outcomes of COVID-19 patients Keywords: antibiotics, antiviruses, COVID-19, clinical improvement, clinical deterioration
Pemberdayaan Relawan Paliatif dalam Peningkatan Pengetahuan Terapi Primer dan Terapi Alternatif Penyakit Kanker Payudara dengan Aplikasi Pikkapa Berbasis Android Godeliva Adriani Hendra; Rollando Rollando; Windra Swastika
I-Com: Indonesian Community Journal Vol 3 No 4 (2023): I-Com: Indonesian Community Journal (Desember 2023)
Publisher : Fakultas Sains Dan Teknologi, Universitas Raden Rahmat Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33379/icom.v3i4.3455

Abstract

Tujuan pengabdian ini untuk meningkatkan pengetahuan relawan paliatif tentang terapi primer dan terapi alternatif kanker payudara. Metode pertama pada pengabdian ini, tim pengabdi Universitas Ma Chung melaksanakan kegiatan homecare bersama dengan relawan dan dokter paliatif RS Baptis Batu. Kegiatan homecare dilaksanakan per hari-nya sekitar 2-3 relawan dengan jumlah pasien kanker payudara sebanyak 4-5 pasien. Metode kedua, hasil kegiatan homecare disampaikan kembali melalui seminar dan workshop yang dihadiri sebanyak 51 relawan. Tes pengetahuan relawan menggunakan kuesioner yang diberikan saat sebelum dan setelah acara. Uji untuk melihat tingkat pengetahuan relawan menggunakan Uji Paired t-test. Hasil pengabdian menunjukkan terdapat perbedaan pengetahuan sebelum dan sesudah diberikan edukasi (p<0,05) dengan hasil rata-rata pengetahuan pre-test sebesar 56,86 dan post-test sebesar 79,02. Kegiatan dari homecare serta seminar dan workshop didokumentasikan pada aplikasi Pikkapa dan relawan diajarkan tentang penggunaan aplikasi. Kesimpulan, adanya peningkatan pengetahuan relawan tentang terapi primer dan alternatif kanker payudara.
Analisis Hubungan Kualitas Hidup Terhadap Penggunaan Kombinasi Obat Antipsikotik Pada Pasien Skizofrenia Godeliva Adriani Hendra
Jurnal Kesehatan dr. Soebandi Vol 8 No 2 (2020): Jurnal Kesehatan dr. Soebandi
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jkds.v8i2.229

Abstract

Therapy of schizophrenic patients often starts with treatment. In addition to psychosocial support therapy, treatment for schizophrenia can use a combination of antipsychotic drugs. The use of a combination of antipsychotic drugs causes various side effects and drug interactions that affect the quality of life of patients. The purpose of this study was to determine the correlation of quality of life to a combination of antipsychotic drugs at the Sumberpucung Health Center. The study design used a cross-sectional retrospectively with descriptive statistical tests and chi-square. There were 37 respondents who were divided into 16 respondents using a combination of A (chlorpromazine, haloperidol) and 21 respondents using a combination of B (Haloperidol, Trihexyphenidyl), (Chlorpromazine, Trihexyphenidyl, Trifluoperazine), (Chlorpromazine, Trihexyphenidyl, Haloperidol), (haloperidol, Clozapine), (Chlorpromazine, Risperidone), (Trihexyphenidyl, Risperidone), (Trihexyphenidyl, Trifluoperazine, Clozapine), (Trihexyphenidyl, Risperidone, Clozapine), (Chlorpromazine, Trihexyphenidyl, Risperidone), (Haloperidol, Trihexyphenidyl, Trifluoperazine), (Haloperidol, Trifluoperazine). Interview with respondents regarding quality of life using the WHOQOL-BREF questionnaire which was divided into 4 domains. Each domain was analyzed based on the good and poor quality of life, history of antipsychotic drug use reviewed from the previous 3 months. The questionnaire has been validated and reliable. The results showed there was a correlation between the quality of life with the use of a combination of antipsychotic drugs (p <0.05). Based on the results of the study found the combination of B provides a better quality of life because the combination of B has lighter side effects for treating symptoms in schizophrenic patients.
Risk Assessment Of Adverse Drug Reactions In Elderly Patients With Chronic Diseases: English Godeliva Adriani Hendra; Eva Monica; Ike Yossy Herawati
Jurnal Kesehatan dr. Soebandi Vol 9 No 2 (2021): Jurnal Kesehatan dr. Soebandi
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jkds.v9i2.306

Abstract

Introduction: The adverse drug reaction (ADR) is 4-7 times more common in elderly patients. That was also related to changes in pharmacokinetics and pharmacodynamics that triggered the emergence of Drug-Related Problems. Objective: The purpose of this study was to assess ADR in elderly patients with chronic diseases using the GerontoNET Score and the Screening Tool of Older People's Prescriptions (STOPP) criteria. Methods: The research design used a cross-sectional study which was analyzed descriptively. The sample consisted of 72 patients, aged more than 60 years, accompanied by chronic diseases, and hospitalized at Waluyo Jati Kraksaan Hospital. The exclusion criteria were patients referred to the Intensive Care Unit. Assessment to see the risk of ADR in elderly patients with chronic diseases using the GerontoNet Score while the wrong type of drug is given to elderly patients using the STOPP criteria. The variables contained in the GerontoNET Score are comorbid conditions ³4 (score= 1), heart failure (score= 1), liver disease (score = 1), the number of drugs such as: £5 (score= 0); 6-7 (score=1); ³8 (score=4), history of ADR (score=2), kidney failure (score=1). Results: The variable with the most ADR risk factors was the number of drugs ³8 drugs as many as 47 patients (65.3%) with GerontoNET score ³4 as much as 70.8%. The types of drugs included in the STOPP criteria are clopidogrel, Arixtra (fondaparinux), beta-blockers, NSAIDs, and furosemide. Conclusion: The risk factor for ADR was the number of drugs ³8 drugs.
EDUKASI HOME PHARMACY CARE TERHADAP KEPATUHAN MINUM OBAT PASIEN TBC (Tuberculosis) DI PUSKESMAS BUGUL KIDUL PASURUAN Susanto, FX. Haryanto; Hendra, Godeliva Adriani; Yulianda, Leli Dwi
Sainsbertek Jurnal Ilmiah Sains & Teknologi Vol. 4 No. 2 (2024): Maret - Sainsbertek Jurnal Ilmiah Sains & Teknologi
Publisher : Ma Chung Press, Universitas Ma Chung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33479/sb.v4i2.310

Abstract

Permainan Edukatif Makanan Sehat dengan Kombinasi Teknik Story Telling bagi Siswa-Siswi TK Dharma Wanita 1 Persatuan Sumber Sekar sebagai Upaya Pencegahan Stunting pada Anak Cesa, Fibe Yulinda; Ismaurasi, Marcelina Fransisca Alecia; Khoiroh, Afifatul; Sentosa, Revin Adis; Wilujeng, Lilis Lestari; Bakti, Amar Ma'ruf Stya; Hendra, Godeliva Adriani
Abdimas Indonesian Journal Vol. 3 No. 2 (2023)
Publisher : Civiliza Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59525/aij.v3i2.330

Abstract

Until now, many food variants have been created by the public to attract buyers' interest. In fact, if food is not processed properly, what happens instead of being beneficial for someone is actually detrimental, one of which becomes a source of disease. Children are the target for instant food sellers who often line up and sell in front of schools. Because it tastes delicious, nowadays children are used to buying these snacks which do not necessarily have good nutritional value. If explored further, poor nutritional value will cause a serious condition in children's development called stunting. Therefore, in Sumbersekar Village there is still no education regarding healthy food, especially from an early age. For this reason, it is necessary to teach children from an early age so that they can avoid foods with low nutritional value. The target for this education is children, therefore story telling regarding healthy food will be given of course also using interactive props so that children are interested and able to remember which food categories are healthy and unhealthy. The results of this service received a very good response and according to the teacher's observations, after these teaching aids were given, children became more aware of bringing vegetables and fruit menus when bringing lunch to school. Evaluation of this service is a more structured observation, especially in the form of a questionnaire for effectiveness and monitoring changes in student behavior before and after being given the story telling service and game tools.
PENGARUH EDUKASI FLIPCHART TERHADAP PERILAKU KETIDAKPATUHAN PENGGUNAAN OBAT ANTIDIABETES SECARA KUALITATIF Dhita Rizki Amalia; Rollando; Hendra, Godeliva Adriani
Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Vol 5 No 3 (2023): December
Publisher : Fakultas Kedokteran Universitas Alkhairaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31970/ma.v5i3.152

Abstract

Diabetes merupakan penyakit menahun atau kronis berupa gangguan metabolik yang ditandai dengan kadar gula darah yang melebihi batas normal. Penelitian ini bertujuan untuk mengetahui gambaran tingkat perilaku ketidakpatuhan penggunaan obat antidiabetes pada kelompok kontrol dan kelompok intervensi sebelum dan sesudah edukasi flipchart. Hasil analisis tingkat ketidakpatuhan, didapatkan adanya penurunan dalam persen ketidakpatuhan pada pertanyaan 2, 5, 6, 7, dan 8 yang cukup tinggi perbedaannya setelah adanya intervensi. Pada pasien kelompok kontrol yang tidak diberikan perlakuan, cenderung konsisten dengan tingkat perilaku ketidakpatuhannya. Pada hasil analisis pola ketidakpatuhan menunjukan bahwa pasien memiliki alasan beragam. Beberapa pasien mengalami ketidakjelasan dalam informasi yang tertera pada label, sehingga menggunakan aturan sendiri. Kecocokan pola ini berkisar diantara 75% hingga 88%. Ada juga pasien yang mengganti obat mereka dengan jamu, serta pasien menghemat penggunaan obat agar cukup digunakan. Kecocokan pola ini berkisar antara 69% dan 94%. Hasil tersebut mengidentifikasi beberapa faktor yang memengaruhi ketidakpatuhan, pemahaman yang kurang baik tentang penggunaan obat, jadwal harian yang padat, dukungan sosial, dan kendala fisik. Meskipun edukasi flipchart berhasil meningkatkan pemahaman pasien dan mengurangi tingkat ketidakpatuhan, masih diperlukan penekanan lebih lanjut pada aspek-aspek tertentu yang menunjukkan ketidakpatuhan yang tinggi setelah intervensi.
Implementation of The "My TB Alarm" Mobile Application as an Educational Instrument in Measuring Adult Tuberculosis Patient Adherence Hendra, Godeliva Adriani; Susanto, FX Haryanto; Choirunniza, Aqidatun Naffiah
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 20, No 2 (2023)
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v20i2.8380

Abstract

Ketidakpatuhan dalam terapi TBC menjadi tantangan utama dalam program pengendalian dan pencegahan TBC. Ketidakpatuhan dalam terapi TBC meningkatkan risiko morbiditas, mortalitas, dan resistensi obat baik pada tingkat individu maupun komunitas. Adapun solusi untuk mengupayakan peningkatan kepatuhan terapi TBC dengan penggunaan mobile application. Tujuan penelitian ini untuk mengetahui pengaruh pemberian mobile application “My TB Alarm” terhadap kepatuhan terapi pasien TBC dan hubungan antara data demografi pasien terhadap kepatuhan pasien TBC. Rancangan penelitian menggunakan one group pretest-posttest design dengan pengambilan data secara prospektif. Pre-test dan pemberian intervensi mobile application “My TB Alarm” diberikan hari ke-1, kemudian hari ke-30 diberikan intervensi kembali dan post-test. Pretest-posttest berupa kepatuhan minum OAT yang berdasarkan selisih waktu scan obat dengan waktu alarm yang dipasang, dimana dikatakan patuh bila selisihnya <2jam. Tidak terdapat hubungan antara usia, jenis kelamin, pendidikan, status menikah, pendapatan, komorbid, IMT, jenis OAT terhadap kepatuhan pasien TBC (p>0,05), namun terdapat hubungan antara jenis TBC terhadap kepatuhan pasien (p<0,05). Terdapat perbedaan yang bermakna rata-rata selisih waktu minum obat antara sebelum dan sesudah diberikan “My TB Alarm” (p=0,021). Kesimpulan, mobile application “My TB Alarm” dapat meningkatkan kepatuhan pada pasien TBC.  
Evaluation of Anti-diabetic Drugs using ATC/DDD and DU90% Methods in Diabetes Mellitus Patients: Evaluasi Obat Antidiabetik menggunakan Metode ATC/DDD dan DU90% pada Pasien Diabetes Melitus Hendra, Godeliva Adriani; Nugraha, Dhanang Prawira; Krisdia, Tuswatul Anggi
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 1 (2024): (March 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i1.16624

Abstract

Background: Diabetes Mellitus (DM), which results from insulin resistance, is closely linked to long-term damage to pancreatic beta cells, organ dysfunction, and organ failure, particularly in the eyes, kidneys, nerves, heart, and blood vessels. The development of the ATC/DDD system is necessary to increase global drug knowledge, ensure equitable drug availability, and promote responsible drug use. Objectives: This study aimed to identify data on patient characteristics and oral anti-diabetic drugs and insulin using the ATC/DDD and DU90% methods. Material and Methods: This study was a cross-sectional evaluation of oral anti-diabetic medications and insulin using the ATC/DDD method and DU90% at the Bala Keselamatan Bokor Turen Hospital from January to December 2022. The inclusion criteria were patients diagnosed with type 1 or type 2 diabetes mellitus, with or without comorbidities, who were treated with oral anti-diabetic medications and a combination of insulin and oral medications. In the present study, the incomplete medical record data served as the exclusion criteria. The sample for this investigation consisted of 238 patients selected using the complete sampling technique. Results: Most patients who used oral anti-diabetic medications and insulin were between the ages of 46 and 65 (71.34%), were female (73.2%), had standard body mass index (BMIs between 18.5 and 25), and had diagnoses of DM + HT (20.73%) and Type II DM (18.29%). Glulisin was the most used anti-diabetic drug, accounting for 589 DDD/100 days of hospitalization, and DU90% was 21.39%. Conclusion: Glulisin is the most frequently prescribed anti-diabetic medication at Bokor Turen Hospital.
Exploring Prescription Patterns and Patient Characteristics in Antiepileptic Therapy: A Retrospective Observational Study Aditya, Martanty; Hendra, Godeliva Adriani; Maitreya, Putera
Academia Open Vol 8 No 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.8.2023.7268

Abstract

This retrospective observational study aimed to provide an overview of prescribed antiepileptic therapy utilization and patient profiles. Conducted at a Neurology Polyclinic, data from December 2022 to January 2023 were analyzed descriptively. Among 35 eligible patients, the majority were male (68.57%), aged 15-25 years (48.57%), with long-standing epilepsy (54.28%), and absence of recent seizures (54.28%) and comorbidities (62.85%). Monotherapy was employed for 51.43%, while 48.57% received combination therapy. Phenytoin emerged as the most frequently prescribed monotherapy (25.71%), and valproic acid combined with phenytoin was the prominent combination (14.28%). This study highlights the prevalence of phenytoin and valproic acid usage, suggesting the need for further investigation into their efficacy and implications for epilepsy management. Highlights: Diverse Prescription Patterns: The study reveals a range of antiepileptic therapy prescriptions, with phenytoin and valproic acid being the predominant choices in both single and combination forms. Patient Profiles and Demographics: The analysis focuses on male-dominated respondents aged 15-25 years, emphasizing the importance of understanding patient characteristics for tailored epilepsy management strategies. Implications for Treatment Strategies: The findings underscore the significance of evaluating the efficacy and clinical implications of commonly prescribed antiepileptic drugs, guiding clinicians in optimizing epilepsy treatment regimens. Keywords: Antiepileptic therapy, Prescription patterns, Patient characteristics, Epilepsy management, Combination therapy.
Co-Authors Aditya Nirwana Amar Ma’ruf Stya Bakti Aprilia, Devi Ratna Aprillia Dian Partisia Bakti, Amar Ma'ruf Stya Bila, Naura Syifa Salsa Choirunniza, Aqidatun Naffiah Chresiani Destianita Yoedistira Dhita Rizki Amalia Elvina Agus Eva Monica Eva Monica Eva Monica, Eva F.X. Haryanto Susanto Fibe Yulinda Cesa FX Haryanto Susanto Haryanto Susanto Ike Yossy Herawati Ismaurasi, Marcelina Fransisca Alecia Khoiroh, Afifatul Krisdia, Tuswatul Anggi Maitreya, Putera Martanty Aditya, Martanty Monika Turnip Nawawi, Achmad Zulkifli Nugraha, Dhanang Prawira Pramesti, Agatha Tri Endha Putri Devy Septya Rahadi, Theresa Dhea Lonika Rehmadanta Sitepu Rinda Puspita Sari Rollando, Rollando Sabrina Handayani Tambun Salsabila Rohadatul Aisy Sentosa, Revin Adis shida, Fika sham Sintia Dina Pranata Suhul Raos Kumawula Ing Gustyas Suliati, Hinda Susanto, FX Haryanto Susanto, FX. Haryanto Wilujeng, Lilis Lestari Windra Swastika Windra Swastika Yulianda, Leli Dwi Yulis Mitra Reformasika