Article Per Year (5 Year)
p-Index From 2020 - 2025
1.456
P-Index
This Author published in this journals
All Journal ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi Dental Journal (Majalah Kedokteran Gigi) Dentin Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI) Odonto dental journal
Melisa Budipramana, Melisa
Department Of Orthodontics, Faculty Of Dental Medicine, Universitas Airlangga
Dentistry Energy Health Professions Medicine & Pharmacology Physics

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Odonto dental journal

 1 
Chitosan From Haruan (Channa Striata) Fish Scale Accelerate Wound Healing By Promoting Angiogenesis And Fibroblast Proliferation Putri, Deby Kania Tri; Fitriyana, Annisa; Raudah, Siti; Wardhana, Agung Satria; Wydiamala, Erida; Sarifah, Norlaila; Budipramana, Melisa
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.%p

Abstract

Background: Damage to the integrity of some body tissues due to trauma commonly referred to as injury can occur intentionally or unintentionally. Angiogenesis and fibroblast proliferation are important stages in the proliferation stage in determining the success of the wound healing process. Chitosan from haruan fish scales has active functional groups in the form of anti-inflammatory and antioxidants that are effective in accelerating wound healing. Method: This study was a pure experimental study with a post-test only design with a control group design which was divided into a treatment group and a control group. The treatment group consisted of chitosan haruan fish scales at concentrations of 1%, 3%, and 5%. The control group consisted of povidone iodine as a positive control and no treatment as a negative control. All rats were injured on the back and then euthanized on days 3, 5, 7, and 14. Result: The chitosan from haruan fish scales affected the formation of new blood vessels and fibroblasts on day-3, increase the number of new blood vessels on day-5, decrease the number of new blood vessels accompanied by increase the number of fibroblasts on day-7, and also decrease the number of fibroblasts on day-14.Conclusion:  3%, and 5% chitosan from haruan fish scale proved to be effective against angiogenesis and fibroblast proliferation in wound healing. 
Co-Authors Arif, Widyandini Aulia Bayu Indra Sukmana Firdaus, I Wayan Arya Krishnawan Fitriyana, Annisa Garcia, Frida Dillenia Contesa Hasnaa Ramadhani Putri Pratami Hatta, Isnur Ichrom Nahzi, Muhammad Yanuar Irnamanda D.H., Irnamanda Maharani Laillyza Apriasari Nurrahman, Tri Oktiani, Beta Widya Putri, Rizqi Risfiana Rahma, Talitha Fatimah Rahmad Arifin Rosihan Adhani, Rosihan Sari, Galuh Dwinta Sarifah, Norlaila Sianiwati Goenharto Siti Raudah Thalca Hamid Tri Putri, Deby Kania Utami, Juliyatin Putri Wardhana, Agung Satria Wibowo, M. Ridhotama Wydiamala, Erida Yunike Christanti