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Human dental pulp mesenchymal stem cells regenerative potential Fadiyan Amriel, Menza; Priyo Prasetyo, Eric; Auzan Fepiosandi, Radixtio; Agustin Wahjuningrum, Dian; Suardita, Ketut; Zora, Zofia; Natan, Daniel; Bin Zainal Abidin, Imran; Ohara, Masaru
Conservative Dentistry Journal Vol. 15 No. 1 (2025): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i1.2025.27-32

Abstract

Background: Stem cells can be divided into mono-potent, oligopotent, multipotent, pluripotent, and totipotent. Dental and oral stem cells are stem cells found in the teeth and mouth that has the potential to develop into various cell types. The rapid development of regenerative dentistry has resulted in the exploration of stem cells, including dental pulp mesenchymal stem cells. Mesenchymal stem cells, have important regenerative potential in repairing dental and surrounding tissues. One of dental stem cells source that have been discovered is dental pulp mesenchymal stem cells. Purpose: This article aims to review the regenerative potential of human dental pulp mesenchymal stem cells (HDPMSCs). Review: HDPMSCs are potential for regenerative dentistry, including regenerative endodontics due to their multipotency, ease of collection, and ability to support tissue repair, immunomodulation, and regeneration across dental, orthopedic, neurological, and cardiovascular applications. Conclusion: The regenerative potentials of HDPMSCs on various treatments are vastly explored by many studies.
SISTEM PENAGIHAN DEBITUR GAGAL BAYAR PINJAMAN ONLINE MELALUI EMERGENCY CONTACT, APAKAH SAH DIMATA HUKUM? Victoria Beatrice Angelica; Ketut Suardita
Jurnal Media Akademik (JMA) Vol. 3 No. 3 (2025): JURNAL MEDIA AKADEMIK Edisi Maret
Publisher : PT. Media Akademik Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62281/v3i3.1637

Abstract

Tujuan studi ini adalah untuk mengkaji sistem penagihan debitur gagal bayar dalam pinjaman online melalui Emergency Contact. Penelitian ini menggunakan metode penelitian hukum normatif dengan pendekatan yang mengutamakan penelitian bahan pustaka atau data sekunder, yang mencakup peraturan perundang-undangan, literatur hukum, dan dokumen terkait lainnya. Pembahasan fokus pada mekanisme penagihan yang dilakukan oleh penyedia pinjaman online melalui kontak darurat yang terdaftar dalam aplikasi pinjaman, serta dampak hukumnya bagi debitur dan pihak ketiga yang tercatat sebagai Emergency Contact. Hasil studi ini diharapkan dapat memberikan informasi yang jelas kepada pembaca bahwa penggunaan Emergency Contact dalam proses penagihan pinjaman online dapat dibenarkan secara hukum, dengan merujuk pada peraturan perundang-undangan yang ada, termasuk Undang-Undang Informasi dan Transaksi Elektronik (ITE) yang melindungi hak-hak privasi dan perlindungan data pribadi pihak yang menjadi Emergency Contact. Dengan demikian, studi ini juga bertujuan untuk menyarankan langkah-langkah perlindungan hukum yang perlu diterapkan agar tidak terjadi penyalahgunaan dalam sistem penagihan yang melibatkan pihak ketiga.
Effectiveness of micro and nano sized propolis with calcium hydroxide combination in inhibiting the formation of Lactobacillus acidophilus biofilm Derice Putri Nourah Serena; Ira Widjiastuti; Setyabudi; Febriastuti Cahyani; Devi Puspitasari; Tiara Dyah Iswari; Suardita, Ketut; Daniyal Lazuardi Ramadhan
Conservative Dentistry Journal Vol. 15 No. 2 (2025): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i2.2025.87-90

Abstract

Background: Lactobacillus acidophilus is involved in secondary caries that can accelerate demineralization of the tooth surface. Bacteria forms biofilm as part of a defense mechanism. One of the caries treatments is direct pulp capping with calcium hydroxide (Ca(OH)2) as the gold standard. Due to its high pH, calcium hydroxide can induce necrosis of pulp tissue when it comes into direct contact. Propolis is a natural material produced by honey bees. Propolis has many benefits including antibacterial effects. Nanoparticles are microscopic particles measuring 1-100 nm, reducing particle size can increase the rate of dissolution and absorption. Purpose: This study aims to prove the difference in the biofilm inhibitory ability of a micro and nano-sized combination of propolis and Ca(OH)2 against L. acidophilus biofilms. Methods: This study used true experimental laboratories research with treatment groups that included a control, combination of micro-sized propolis and Ca(OH)2 and combination of nano-sized propolis and Ca(OH)2. Results: The results showed that there was a significant difference between the micro and nano-sized combination of propolis and Ca(OH)2 in inhibiting biofilm growth, with the combination of nano-sized propolis and Ca(OH)2 showing higher effectiveness compared to the micro-sized one. The combination of nano-sized propolis and Ca(OH)2 produced an inhibition value of 84.35%, while the micro-sized one produced an inhibition value of 77.18%. Conclusion: The combination of nano-sized propolis and Ca(OH)2 had a greater biofilm inhibition compared to the combination of micro-sized propolis and Ca(OH)2.