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All Journal Media Ilmu Keolahragaan Indonesia The Indonesian Biomedical Journal Majalah Kedokteran Nusantara The Journal Of Medical School Indonesian Journal of Medicine Sumatera Medical Journal Jurnal Keperawatan Priority Journal of Telenursing (JOTING) Indonesian Journal of Global Health research Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) The Journal of Society Medicine (JSOCMED) Jurnal Penyakit Dalam Indonesia
Santi Syafril, Santi
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Jurnal Penyakit Dalam Indonesia

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Hubungan Visceral Adiposity Index dengan Neuropati Diabetik Perifer pada Pasien Diabetes Melitus Tipe 2 Sanusi, Muhammad Arif; Lubis, Dian Anindita; Syafril, Santi
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Abstract

Introduction. Type 2 diabetes mellitus (T2DM) is the leading metabolic disease in Indonesia. Diabetic peripheral neuropathy (DPN), a major complication of T2DM, was associated with insulin resistance and adipose dysfunction. Visceral adiposity index (VAI) is a tool to measure visceral fat as the indicator of adipose dysfunction and insulin sensitivity. The association between VAI and DPN has not been widely researched, especially in Indonesia. This study aims to assess the association between them. Methods. This was a cross-sectional study conducted on adult patients (aged ≥18 years) with T2DM at H. Adam Malik General Hospital, Medan, from December 2024 to March 2025. DPN was assessed using the Michigan Neuropathy Screening Instrument (MNSI), consisting of a questionnaire (MNSI A) and physical examination (MNSI B). VAI was calculated using waist circumference, body mass index (BMI), triglyceride level, and high-density lipoprotein (HDL) cholesterol level. A bivariate analysis was conducted to compare mean VAI values between patients with and without DPN and to assess correlations between VAI and MNSI scores. Results. From a total of 80 subjects, the average age was 56 years (SD 9), and the majority were female (56.3%). The median VAI value in the DPN group was 2.863 (0.401–11.665), slightly higher than in the non-DPN group, which was 2.549 (0.781–17.414), but the difference was not statistically significant (p=0.34). No statistically significant correlation was found between VAI and MNSI A score (r=0.092; p=0.42) or MNSI B score (r=0.12; p=0.31). Conclusion. There was no significant association between VAI and DPN in patients with T2DM.
Co-Authors Awaluddin Saragih Aznan Lelo Bernando, Andri Dairion Gatot, Dairion dharma Lindarto, dharma ELMAN BOY Ginting, Almaycano Handayani, Savina Harahap, Juliandi Ihsan, Brama Imelda Rey Irawaty, Noni Kembaren, Tambar Lubis, Dian Anindita Mardia, Andri Iskandar Merlin, Asri Pangaribuan, Jessica Patricia Prianwari, Catur Rahma, Hadiyatur Rahmad Isnanta, Rahmad Ratna Akbari Ganie, Ratna Akbari Ricke Loesnihari Sanusi, Muhammad Arif Sembiring, Rosita Juwita Sholat, Alfi Dewi Siregar, Dewi Indah Sari Siregar, Jelita Situmorang, Immanuel Sri Sumartiningsih Sugeng, Santoso Sylvana, Dhini Tarigan, Amira Permatasari Theresia, Lydia Yetty Machrina Yulindaa, Wina Yusni Yusni