Article Per Year (5 Year)
p-Index From 2021 - 2026
1.431
P-Index
This Author published in this journals
All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kedokteran Diponegoro Majalah Kedokteran Bandung Jurnal Kesehatan Masyarakat Indonesian Journal of Cancer Chemoprevention Oto Rhino Laryngologica Indonesiana Medica Hospitalia Indonesian Journal of Global Health research Indonesian Journal of Cancer
Zulfikar Naftali, Zulfikar
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 12 Documents
Search

 1   2 
The Influence of Nutritional Factors on the Quality of Life of Cancer Patients: A Scooping Review Efendi, Dhanang; Naftali, Zulfikar; Handayani, Fitria
Indonesian Journal of Global Health Research Vol 6 No S6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS6.4592

Abstract

Cancer is a condition of abnormal cell growth, cells lose their normal control and mechanisms resulting in rapid and uncontrolled cell growth, as well as local tissue invasion and distant metastases. Quality of life is influenced by health status. A decrease in nutritional status often occurs as a result of cancer and its therapy. Due to the lack of food intake such as appetite, swallowing ability, absorption in the body and treatment therapy actions taken, coupled with chemotherapy. The aim of this study was to determine the effect of nutrition on the quality of life of cancer patients. Methods: Researchers used the scoping review method. The article search used databases from Sciencedirect, Scopus, and Pubmed with the research time January 2019 to December 2023, with the keywords influence"AND ‘nutrition’ AND ‘quality life’ AND ‘Patient’ AND ‘Cancer’. The results were 10 articles analyzed, all of which were quantitative articles. Based on identification, there are 67 articles from search engines from Sciencedirect, Scopus, and Pubmed. The final results obtained were 10 articles that fit the criteria after going through the selection process. Nutritional factors have an important role in the quality of life of patients. The better the nutrition obtained, the higher the patient's quality of life. Researchers used the PEO question format (population, exposure, outcome) to find related research articles. Improved nutrition helps prevent weight loss, which can affect tolerance to treatment and reduce its side effects. The nutritional status of cancer patients tends to change and deteriorate during intensive treatment. Maintenance of a healthy weight during cancer therapy is considered important in health management. By understanding the relationship between nutrition, diet and quality of life in cancer patients, appropriate nutrition interventions can be designed to improve treatment outcomes and patient well-being.
Effect of Astaxanthin Supplementation in Preventing Anemia in Head and Neck Cancer Patients Receiving Cisplatin Chemotherapy Aminullah, Yusuf; Subagio, Hertanto Wahyu; Santosa, Damai; Naftali, Zulfikar
Indonesian Journal of Cancer Chemoprevention Vol 14, No 2 (2023)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev14iss2pp72-82

Abstract

The incidence of anemia due to reactive oxygen species (ROS) in patients with head and neck cancer (HNC) can be caused by a side effect of cisplatin chemotherapy, namely myelosuppression. In the presence of ROS, external antioxidants are needed, including astaxanthin as an antioxidant to neutralize and fight ROS in preventing anemia. This study aims to prove and analyze the antioxidant effect of astaxanthin in preventing anemia in HNC patients due to cisplatin chemotherapy for 3 weeks. The study design was a randomized controlled trial pre-post test design, involving 42 research subjects who were randomly divided into two groups, then 3 cc of blood was taken I to check the hemoglobin level and the number of erythrocytes. The treatment group was given astaxanthin 2x4 mg and the control group was given a combination of vitamin C 1x500 mg and vitamin E 1x250 IU for 3 weeks then 3 cc of blood was taken II to check hemoglobin levels and erythrocyte counts. The independent variable is intake of astaxanthin, the dependent variable is hemoglobin level and the number of erythrocytes and the confounding variables are age, sex, type of HNC, stage of HNC, ECOG and BMI. Data analysis was performed by the Descriptive test, Levene test, Shapiro Wilks, Wilcoxon test, and Mann-Whitney test. The significance of the hypothesis test was obtained with p<0.05. The 42 research subjects met the inclusion criteria, most aged between 41-50 years, male and female ratio 2:1, The most HNC were Nasopharyngeal Cancer, the most HNC stage was stage IV, the most HNC performance status was ECOG I and the most HNC patients had normal BMI. There was a significant difference in hemoglobin levels p=0.012 (p<0.05) and the number of erythrocytes, p=0.04 (p<0.05) between the treatment and control groups. There was a significant difference in hemoglobin levels after therapy in the treatment and control groups p=0.012 (p<0.05) and the number of erythrocytes p=0.04 (p<0.05) between the treatment and control groups. Astaxanthin can prevent anemia in the form of decreased hemoglobin levels and the number of erythrocytes in HNC patients who receive cisplatin chemotherapy.Keywords: astaxanthin, anemia, HNC, cisplatin, ROS.
Co-Authors Aminullah, Yusuf Aminuyati Arwanto, Arwedi Budiarti, Rery Dewi, Anna Mailasari Kusuma Efendi, Dhanang Farokah, Farokah Fitria Handayani Hendaraningrum, Farah Hendro Purnomo Herjanto, Ferry Hertanto Wahyu Subagio Inardi, Yoke Kurniawan Kanti Yunika, Kanti Liemiyah, Rikha Marliyawati, Dwi Murbani, Ita Muyassaroh Muyassaroh Pujo Widodo, Pujo Ruspita, Dian Ayu Santosa, Damai Sarah, Diah Ayu Siti sayuti, fajri imam Sekarwangi, Yuni Retno Subekti, Rohmatullah Suprihati - Ulfa, Loriana Willy Yusmawan, Willy Yanuar Iman Santosa Yunika, Kanthi