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All Journal Medula JK Unila (Jurnal Kedokteran Universitas Lampung) JCOMENT (Journal of Community Empowerment) Sains Medisina Jurnal Mahasiswa Ilmu Kesehatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Praba: Jurnal Rumpun Kesehatan Umum Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Ramadhan Triyandi
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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Journal : Medula

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Kajian Literatur: Aktivitas Antibakteri dari Ekstrak Daun Sirih (Piper betle L.) Terhadap Bakteri Staphylococcus aureus Nur Amrillah; Ramadhan Triyandi; Muhammad Iqbal; Citra Yuliyanda Pardilawati
Medula Vol 13 No 4 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i4.754

Abstract

Bacterial infection is a major health problem that affects many humans. The therapy used to treat bacterial infections generally uses antibiotics. However, the inappropriate and continuous selection and use of antibiotics can lead to the occurrence of antibiotic resistance in humans. Staphylococcus aureus is one of the most involved pathogenic bacteria in human bacterial infections. This bacterium is found in the normal skin microbiota of animals and humans. Staphylococcus aureus has infected as many as 20-30% of the healthy human population. Staphylococcus aureus produces antibiotic neutralizing enzymes resulting in resistance to many antibiotics. Many developing countries use medicinal plants as an alternative to treat infections. More than 700 species of betel leaf are found in the North and South of the world and are widely grown in most countries such as Indonesia, India, Sri Lanka, Malaysia, the Philippines, as well as other countries in Southeast Asia and East Africa. Boiled betel leaf (Piper betle L.) has been widely used in Indonesia as an alternative medicine. Betel leaf extract contains several chemical components such as terpenoids, alkaloids and phenolic compounds such as flavonoids, tannins and saponins. These components are known to have strong potential as antibacterial. This study article aims to find out whether betel leaf extract (Piper betle L.) has the ability to inhibit bacterial growth and what concentration of the extract is needed so that there is inhibition of activity and growth of Staphylococcus aureus.
Potensi Astragalus Sebagai Terapi Adjuvan Pada Pasien Glomerulonefritis Alfina Indah Nabila; Nabila Rayhan Yasmin; Rani Himayani; Ramadhan Triyandi
Medula Vol 13 No 5 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i5.783

Abstract

Glomerulonephritis is a medical term used to describe a condition that involves some kidney damages. Glomerulonephritis is an abnormality of the kidney that may lead to end-stage renal disease (ESRD). The current glomerulonephritis therapy is considered not fully effective due to the possibility of additional morbidity and complications that may occur. The use of Astragalus as adjuvant therapy can inhibit the progression of glomerulonephritis. The journals, that was reviewed, obtained from the Google Scholar, Sciencedirect, PubMed, and Springer with a publication year range of 2009-2023. The journals were selected to obtain valid and reliable journals, then do a literature review and article writing. Astragalus membranaceus has a bioactive content that can act as an immunomodulator, antiinflamation, and renoprotector. Astragalus is able to improve kidney function through IL-6 secretion and improve kidney interstitial fibrosis. Administration of Astragalus in combination with conventional therapy can reduce serum creatinine and proteinuria. Astragalus has potential as adjuvant therapy in glomerulonephritis patients.
Co-Authors Afriyani Agaphe Suluh Brahmantio Agnes Monica Murisla Ahmad Fauzi Alfina Indah Nabila Arifah Putri Desenia Arini Puspita Sari Atri Sri Ulandari Baehaqi Bayu Anggileo Pramesona Citra Yuliyanda Pardilawati DWi Aulia Ramdini Dwita Nurmumpuni Exsa Hadibrata Fathia Radinda Salsabila Femmy Andrifianie Fredison Fredison Ihsanti Dwi Rahayu Khairun Nisa Liana Sidharti Muhammad Iqbal Nabila Rayhan Yasmin Natalia Michelle Simatupang Nur Amrillah Oktoba, Zulpakor Panca Bayu Rahmayani, Fidha Rani Himayani Rizki Hanriko Siti Husna Suharmanto Umniyah Tsabitah Zahrani Vadiyani Fricillya Puteri Zahra Fadilatusya'adah