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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN e-GIGI MEDIA MEDIKA INDONESIANA Jurnal Kedokteran Diponegoro Journal of Biomedicine and Translational Research Dentino: Jurnal Kedokteran Gigi Molecular and Cellular Biomedical Sciences (MCBS) JOMIS (Journal of Midwifery Science) JIFI (Jurnal Ilmiah Farmasi Imelda) Acta Odontologica Indonesia
Lusiana Batubara
Department Of Medical Biology And Biochemistry, Faculty Of Medicine, Universitas Diponegoro, Semarang
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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THE EFFECT OF GLYCERIN APPLICATION ON SURFACE HARDNESS OF NANOHYBRID COMPOSITE RESIN IMMERSED IN ALCOHOLIC MOUTHWASH Tio Aldi Nugroho; Gloria Fortuna; Lusiana Batubara; Nadia Hardini
Dentino : Jurnal Kedokteran Gigi Vol 8, No 1 (2023)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v8i1.16088

Abstract

ABSTRACT Background: Composite resin is the most commonly used restorative material. One of properties composite resins is surface hardness can change due to exposure of the restorative material to oral fluids such as alcoholic mouthwash. The degradation that occurs due to alcoholic mouthwash is able to reduce the surface hardness of the nanohybrid composite resin. Glycerin is able to increase the hardness of the composite resin by perfecting the polymerization that occurs in the restorative material when exposed to light cured light. Objectives: This study aims to determine the effect of glycerin application on the hardness of nanohybrid composite resins after immersion in alcoholic mouthwash. Methods: A total of 32 samples of nanohobride composite resin in this study were made in the form of a cylinder with a diameter of 5 mm and a thickness of 2 mm. The nanohybrid composite resin samples were divided into control and treatment group by applying glycerin on the sample surface before light curing. The study was continued by immersing the sample into artificial saliva for 24 hours and alcoholic mouthwash for 6 hours. The research continued with surface hardness test using the Vickers Hardness Tester. Result : Paired bivariate T test showed a significant difference between the two groups (p<0.005). The conclusions of this study indicate that the application of glycerin has an effect on the hardness of the nanohybrid composite resin after immersion with alcoholic mouthwash. Conclusion: The application of glycerin affects the hardness of the nanohybrid composite resin after immersion with alcoholic mouthwash.  Key words: Glycerin application, Hardness, Nanohybrid composite resin
Pengaruh Komposisi Jenis Biji Kopi terhadap Keparahan Diskolorasi Gigi Janto, Matthew Kennard Hery; Purnomo, Brigitta Natania Renata; Hardini, Nadia; Batubara, Lusiana
Acta Odontologica Indonesia Vol 1, No 1 (2025): June Edition
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/actodont.26957

Abstract

Coffee can cause discoloration in the hard tissues of teeth due to the presence of chlorogenic acid, which acts as a staining agent. Different types of coffee bean compositions have varying levels of staining agents. This study aims to investigate the influence of coffee bean composition (100% Arabica, 70%-30% Arabica-Robusta blend, 50%-50% Arabica-Robusta blend, and 100% Robusta) on the severity of tooth discoloration. This research is a quasi-experimental study with a pre-test and post-test control group design to assess the effect of coffee immersion on tooth color change (ΔE). The study involved 24 human premolar tooth samples divided into four treatment groups. Before treatment, the color of the samples was measured (pre-test data), and then the samples were immersed in a coffee solution for 48 hours. After immersion, the color of the samples was measured again (post-test data). Paired t-tests were conducted to determine the significance of differences between pre-test and post-test treatment. Subsequently, Kruskal-Wallis tests were performed to assess the significance of differences among the four treatment groups. Paired t-tests for all groups showed significant results (p < 0.05). Kruskal-Wallis tests indicated a significant difference among the four treatment groups (p < 0.05), with the highest tooth color change (ΔE) observed in the 100% Robusta coffee treatment group and the lowest color change in the 100% Arabica coffee treatment group. The composition of coffee bean types has an impact on the severity of tooth discoloration.
EFEK EKSTRAK TANAMAN ASHITABA PADA KADAR SERUM ALKALIN FOSFATASE (ALP) PADA TIKUS YANG TERPAPAR LUKA BAKAR Johan, Andrew; Kusmiyati Tjahjono; Wenda Yoanda; Dwi Ngestiningsih; Lusiana Batubara
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 5 No. 1 (2021): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (534.742 KB) | DOI: 10.52943/jifarmasi.v5i1.662

Abstract

Serum alkaline phosphatase (ALP) levels increases in burn tissue damage. Several bioactive compounds found in Ashitaba, are expected to reduce serum ALP levels and enhance the process of wound healing. This study aims to prove that administration of oral Ashitaba extract can reduce serum ALP levels in rats exposed to burn trauma. This study uses true experimental post-test control group design with a total of 20 Sprague dawley rats as samples. All samples were inflicted with 2nd degree burn wound and divided into 2 groups, treatment group (Ashitaba extract 300 mg/KgBW) and control group. Blood serum were analyzed for ALP levels on the 2nd, 8th and 14th days. Kinetic-IFCC method was used to find serum ALP levels. Data was analyzed using Mann-Whitney Test, paired T-test amd independence T-test. Scalded wound size was measured macroscopically over the course of 21 days to find contracture rate. In conclusion, Ashitaba extract is not proven to significantly reduce the serum ALP levels, increase contracture rate and enhance burn wound healing process. However, there was slight increase in contracture rate in treatment group as compared to control group. In addition, there was a lower ALP levels in treatment group as compared to control group in day 8.
THE EFFECT OF HONEY PINEAPPLE JUICE (Ananas conosus var. cayenne) ON DISCOLORATION OF COMPOSITE RESIN DUE TO COFFEE IMMERSION Saskya Aldina Nur Amalina; Nadia Hardini; Lusiana Batubara; Brigitta Natania Renata Purnomo
Dentino: Jurnal Kedokteran Gigi Vol 10, No 2 (2025)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v10i2.24163

Abstract

Background: Discoloration of the composite resin can be cleaned using chemicals. However, chemicals are still being debated because they have some side effects. This has led researchers to look for natural materials that can be used to clean composite resins. Honey pineapple contains organic acids and the enzyme bromelain which can be used to clean teeth. Objectives: This study aims to determine the effect of honey pineapple juice on the color change of composite resin due to coffee immersion after soaking honey pineapple juice for 1, 3, and 5 days. Methods: This type of research is an experimental laboratory with a pre test - post test group design. The research data were tested using paired t test and one way ANOVA test. Results: The results showed that there were differences in the color change of the composite resin due to coffee immersion after soaking honey pineapple juice for 1, 3, and 5 days. Conclusions: There is an effect of honey pineapple juice on the color change of the composite resin due to coffee immersion and there are differences in the color change of the composite resin due to coffee immersion after soaking honey pineapple juice for 1, 3, and 5 days. The highest color change occurred in immersion for 5 days. Keywords: Coffee Immersion, Discoloration of composite resin, Honey pineapple juice
Co-Authors Adrian Stefanus Herawan Andrew - Johan Andrew Johan Ari Budi Himawan Ashauma Aksanul Muttaqin Asih Budiastuti Ayu Khoirun Nisa Banundari Rachmawati Brigitta Natania Renata Purnomo Devina Afraditya Paveta Diah Ajeng Purbaningrum Djuara P Lubis Dodik Pramono Donna Hermawati Dwi Ngestiningsih Edward Kurnia Setiawan Limijadi Endang Sri Sunarsih Eva Annisaa Fathur Nur Kholis Fulyani, Faizah Gabriela Rolanda Gloria Fortuna Hardini, Nadia Hernanda Haudzan Hakim Indah Saraswati Indraswari, Darmawati A. Innawati Jusup Irene Oinike Janto, Matthew Kennard Hery Kurniati, Steffi Kusmiyati Tjahjono Kusmiyati Tjahjono DK Nabilah Saniyya Wahyudi Nabilla Nurcahya Junior Nadia Hardini Nazila Tsalisati Hadaita Pardosi, Fransiska M. Prihatiningsih, Tyas Purnomo, Brigitta Natania Renata Putri Theresia Lemmo Ate Bancin Rahmadani Widya Atmani Regina Oktavia Rejeki Andayani Rahayu Rizki Nurida Rahmawati Santoso Santoso Saskya Aldina Nur Amalina Tania Meysavira Fawzi Taufik Eko Nugroho Tinanda Tarigan Tio Aldi Nugroho Tri N. Kristina, Tri N. Wenda Yoanda Widyawati Widyawati Wikanta, Edmond Rukmana