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Antimicrobial Activity Test of Ethanol Extract of Forest Betel Leaves (Piper aduncum L.) Diza Sartika; Epi Supri Wardi; Dyah Komala Putri; Miftahur Rahmi
DIVERSITAS HAYATI Vol. 3 No. 2 (2025): DIVERSITAS HAYATI: Journal of Conservation and Biological Resources
Publisher : UIN Sulthan Thaha Saifuddin Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30631/pbpqm618

Abstract

Abstract. Forest betel (Piper aduncum L.) is a herb that is easily found as a wild plant known to contain secondary metabolite compounds, namely flavonoids, tannins, steroids, phenolics and alkaloids. The purpose of this study was to determine the antimicrobial activity of ethanol extract of forest betel leaves (Piper aduncum L.) against Escherichia coli and Staphylococcus aureus bacteria and Candida albicans fungi as well as the minimum inhibitory concentration (MIC) and minimum bacteriside concentration (MBC) of the extract. The method used in the activity test is the Kirby-Bauer method and in the MIC and MBC tests using the optical density (OD) measurement method using a UV / VIS spectrophotometer. The results of testing antimicrobial activity against Escherichia coli bacteria have the largest average inhibition zone at a concentration of 20% (7.86 mm) which is included in the weak category. While in Staphylococcus aureus and Candida albicans, the 80% extract concentration has the largest average inhibition zone, 12.72 mm and 18.54 mm respectively, which is included in the moderate category. Testing the minimum inhibitory concentration (MIC) of the extract against the test microbes showed that in all three test microbes the MIC was obtained at a concentration of 10% extract. testing then continued with the minimum bacteriside concentration (MBC) there were no results because all concentrations on all test microbes showed microbial growth.
Senam Terapeutik Tingkatkan Kesehatan Pasien Penyakit Degeneratif di Kabupaten Bungo Jhony Hendra; Deka Ismi Mori Saputra; Yessy Fitriani; Diza Sartika; Shilvia Arienda; Iren Arsima Natasya; Karin Okta Aditia
Jurnal Medika: Medika Vol. 4 No. 4 (2025)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/9jn46y36

Abstract

Degenerative diseases are a major public health problem in Indonesia, especially in Bungo Regency. Various efforts have been made to prevent them, one of which is through gymnastics. Gymnastics is an activity carried out to maximize body function through movement. Gymnastics is the right medium to restore body function and improve the quality of life of degenerative patients through therapeutic gymnastics, including; heart gymnastics, brain gymnastics, rheumatic gymnastics, and diabetes mellitus gymnastics. Gymnastics is very popular among various groups, including the elderly, because it creates a pleasant and joyful atmosphere. The results of interviews with the community service team and partners of the Muara Bungo I Community Health Center UPT revealed that there are still many patients with degenerative diseases. Therefore, the implementation of therapeutic gymnastics is a highly desired need by partners. Solutions to these partner problems include providing assistance on the importance of therapeutic gymnastics for degenerative patients and health checks. The purpose of this community service activity is to improve body function and the quality of life of patients with degenerative diseases. The method used is the interview method. The results of this community service included outreach activities, increased knowledge, and the implementation of therapeutic exercises to improve body function and the quality of life for patients with degenerative diseases. Patients were able to perform therapeutic exercises to maximize their function.
EFEKTIVITAS SALEP FRAKSI N-BUTANOL DAUN SIRIH HIJAU (Piper betle L.) TERHADAP PENYEMBUHAN LUKA BAKAR MENCIT Diza Sartika
Jurnal Kesehatan Medika Saintika Vol 15, No 2 (2024): Desember 2024
Publisher : Stikes Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jkms.v15i2.2930

Abstract

Luka bakar merupakan keadaan kerusakan jaringan yang disebabkan kontak dengan sumber panas. Daun sirih mengandung beberapa kandungan senyawa aktif seperti, tanin, flavonoid dan fenolik. Kandungan tersebut dapat membantu proses penyembuhan luka sebagai antiinflamasi, antimikroba dan antioksidan. Tujuan dari penelitian ini untuk mengetahui efektivitas fraksi n-butanol daun sirih hijau konsentrasi 15% terhadap penyembuhan luka bakar. Terdapat 3 kelompok hewan uji, yaitu kelompok 1 basis salep, kelompok 2 pembanding TekasolĀ® dan kelompok 3 fraksi n-butanol daun sirih hijau konsentrasi 15%. Parameter pengamatan yaitu persentase penyembuhan luka bakar, waktu epitelisasi dan histopatologi. Hasil penelitian menunjukan bahwa kelompok 3 memiliki hasil paling baik pada persentase penyembuhan luka bakar dengan persentase 98,38%. Rata-rata waktu epitelisasi basis salep hari ke-15, pembanding hari ke-14 dan fraksi hari ke-13. Hasil uji histopatologi kelompok fraksi hari ke-21 mendapatkan hasil skor yaitu 3 dengan sel fibroblast >50 sel, serabut kolagen saling terikat sempurna, epitelisasi sedang dan inflamasi incomplate. Kesimpulan dari penelitian ini adalah salep fraksi n-butanol daun sirih hijau efektif terhadap penyembuhan luka bakar konsentrasi 15%.