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All Journal Majalah Kedokteran Gigi Indonesia Jurnal Kesehatan Gigi Dental Journal (Majalah Kedokteran Gigi) Journal Of Vocational Health Studies B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah Jurnal Material Kedokteran Gigi JATI EMAS (Jurnal Aplikasi Teknik dan Pengabdian Masyarakat) Mandala of Health : A Scientific Journal Medical and Health Journal Journal of Dental and Biosciences
Widyaningsih, Pratiwi Nur
Jurusan Kedokteran Gigi Fakultas Kedokteran Unversitas Jenderal Soedirman
Humanities Dentistry Education Engineering Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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Effectiveness of vitamin D3 supplementation with protein realimentation in osteoblast and osteoclast of the maxilla of breastfed malnourished rat infants Hidayah, Riski Amalia; Kurniawan, Aris Aji; Widyaningsih, Pratiwi Nur; Rakhmawati, Rakhmawati
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.78293

Abstract

Child malnutrition can happen because of lack of nutrition during pregnancy. Malnutrition can cause low birth weight in babies. This can cause jaw and alveolar bone abnormalities that can lead to malocclusion, periodontitis, and others. This condition can affect bone cells, such as osteoblast and osteoclast. Vitamin D3 supplementation accompanied by protein realimentation may promote optimum bone growth. This research aims to investigate the effect of protein realimentation and vitamin D3 on osteoblast and osteoclast of malnourished rat pups’ maxilla. In this research, the rat pups were divided into 5 groups: a positive control group (K+), a negative control group (K-), and 3 treatment groups (P1, P2, and P3). The subjects of this research were 10 male and 30 female Wistar rats. A condition of malnutrition was induced in the rat pups and they were given vitamin D3 supplementation with protein realimentation. Rat pups in each group were euthanized on the 22nd day to observe the number of osteoclast and osteoblast in the maxilla. The results showed that the number of osteoblasts between normal and malnourished rats was significantly different (p value < 0.05), but the number of osteoclasts between rats in the control and treatment groups was not significantly different. Administration of vitamin D3 may affect the number of osteoblasts and may not affect the number of osteoclasts on bone. The effective dose of vitamin D3 is 0.36 IU/day.
EFFECT OF DIFFERENT TYPES OF SLEEP DEPRIVATION AND SLEEP RECOVERY ON SALIVARY PH Handayani, Fani Tuti; Widyaningsih, Pratiwi Nur; Arjadi, Fitranto
Journal of Vocational Health Studies Vol. 4 No. 3 (2021): March 2021 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V4.I3.2021.95-99

Abstract

Background: Salivary pH can rise or fall influenced by intrinsic and extrinsic factors. Sleep deprivation is one example of intrinsic factors. Sleep deprivation causes a reduction in sleep time at a certain time. Purpose: Analyze the effect of different types of sleep deprivations and sleep recovery on salivary pH. Method: This study was experimental research with a post-test only with a control group design. Thirty white Wistar strain rats were randomly divided into 5 groups: healthy control group (KI), partial sleep deprivation (PSD/KII), total sleep deprivation (TSD/KIII), partial sleep deprivation, and continued sleep recovery (PSD+SR/KIV) and total sleep deprivation and continued sleep recovery (TSD+SR/KV). The treatment is carried out on a single platform method. Salivary pH was measured with the help of color-coded pH strips that were given grading after the completion of sleep deprivation induction. Result: The mean decrease in salivary pH was highest in the TSD group. One Way ANOVA test showed significant differences (p <0.05) in the control group with PSD and TSD, the PSD group with PSD+SR, TSD group with PSD+SR and TSD+SR. Conclusion: Sleep deprivation is proven to reduce the pH of Saliva. Total sleep deprivation is a chronic condition that has the most influence on decreasing salivary pH. The effect of decreasing salivary pH due to sleep deprivation is proven to be overcome by sleep recovery.
PROLIFERATION AND APOPTOSIS IN RAT MODELS OF ORAL SQUAMOUS CELL CARCINOMA INDUCED BY CAPSAICIN EXTRACT NANOPARTICLE GEL Widyaningsih, Pratiwi Nur; Aniowati, Fitri; Naim, Cantika Nadrotan; Anggraeni, Nova Dwi
Journal of Vocational Health Studies Vol. 7 No. 2 (2023): November 2023 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V7.I2.2023.100-106

Abstract

Background: Oral Squamous Cell Carcinoma (OSCC) is highly invasive neoplasm of oral epithelial tissue that is moderately differentiated and tends to metastasize rapidly. Capsaicin, a pungent phytochemical in red peppers, exhibits both anti-proliferative and potential pro-cancer effects on human cancer cell lines. Purpose: Determine the proliferation and apoptosis between five groups of rats induced OSCC. Method: 5 groups of treatment; C- (untreated rats), C+ (induced by DMBA), E1 (exposed to DMBA and given cisplatin), E2 (induced by DMBA and Capsaicin extract nanoparticle gel with 1% concentration), and E3 (induced by DMBA and Capsaicin extract nanoparticle gel with a concentration of 3.3%). Maceration method was used to obtain Capsaicin extract from green cayenne pepper, then made into nanoparticle gel. Tissue samples were taken after the treatment was completed, then they were pathologicallyobserved histopathological using IHC to assess apoptic activity via the TUNEL method and proliferative activity using PCNA. Result: The proliferative activity in the E1 group had a significant difference compared to the E2 and E3 groups. E2 and E3 were not significantly different (p-value ≥0.05). Apoptotic activity in Group E1 indicated a significant difference from the E2 group and was not significantly different from the E3 group, whereas the E2 and E3 groups were significantly different from each other (p-value ≤0.05). Conclusion: The research showed that Capsaicin nanoparticle gel increased apoptotic activity while decreasing proliferative activity in different treatment groups of the OSCC rat model.
KONSENTRASI EKSTRAK ETANOLIK DAUN PEPAYA (Carica papaya L.) TERHADAP PERUBAHAN WARNA BASIS GIGI TIRUAN RESIN AKRILIK POLIMERISASI PANAS Purnama, Ryana Budi; Laksitasari, Anindita; Handayani, Fani Tuti; Widyaningsih, Pratiwi Nur; Rahmawati, Dewi; Milla, Dzhofirotul; Artanti, Evania Bellinda; Nahya, Bintan
Mandala Of Health Vol 17 No 2 (2024): Mandala of Health: a Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2024.17.2.12218

Abstract

Heat-cured acrylic resin is one of the materials used in making denture bases which has the disadvantage that it easily absorbs water and can make discoloration. Papaya leaves (C. papaya L) contain phenolic compounds (C6H6OH-) which can affect the color change of heat-cured acrylic resin. The purpose of this study is to determine the effect of various concentrations of papaya extract on discoloration of the heat-cured acrylic resin denture base. This experimental research is done in vitro at a laboratory using papaya leaf extract (C. papaya L) concentrations of 5%, 10%, and 20%. Thirty two samples of acrylic resin plates were divided into 4 groups, namely the immersion treatment group in papaya leaf extract concentrations of 5%, 10%, and 20%, and the negative control group in the form of aquadest soaking. The color change test was carried out using a UV-visible spectrophotometer. Data was analyzed using the One-Way ANOVA followed by Post-Hoc LSD test. The results of the study showed that there was a very significant difference in the mean value of color change between the treatment groups soaking in papaya leaf extract at concentrations of 10% and 20% and the control group, while at 5% concentration there was no significant difference from the control group. The lowest mean absorbance value was in the distilled water immersion group of 3.341350 ± 0.0942091 and the highest mean absorbance value was in the 20% immersion group of 3.553638 ± 0.0227829. This study concluded that there is an effect of various concentrations of papaya leaf extract on discoloration of the heat-cured acrylic resin denture base. Keywords: Carica papaya L, discoloration, acrylic resin, denture base.
Perbandingan Tingkat Kekasaran Permukaan Glass Ionomer Cement Konvensional Berdasarkan Variasi Jumlah Hisapan Rokok Kretek Non-Filter : Studi In Vitro Bimantoro, Muhammad Satriyo; Dwiandhono, Irfan; Widyaningsih, Pratiwi Nur
Journal of Dental and Biosciences Vol 2 No 01 (2025): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2025.2.01.13623

Abstract

Latar belakang: Glass ionomer cement (GIC) konvensional merupakan bahan restorasi gigi yang bersifat antikariogenik dan dapat melepaskan flouride. Merokok dapat mempengaruhi sifat fisik GIC. Kekasaran permukaan merupakan salah satu sifat fisik bahan restorasi yang dapat memengaruhi keberhasilan restorasi. Tujuan dari penelitian ini adalah untuk mengetahui kekasaran permukaan GIC setelah hisapan asap rokok kretek non filter. Metode: Penelitian ini dilakukan di laboratorium secara eksperimental dengan desain pretest - posttest control group design sejumlah 32 spesimen GIC dibagi menjadi empat kelompok, yaitu kelompok perlakuan diberikan paparan 75, 150, dan 250 hisapan rokok kretek non filter, dan kelompok kontrol diberikan perendaman air liur buatan tanpa paparan asap rokok kretek non filter. Seluruh perlakuan dilakukan selama 21 hari. Kekasaran permukaan diukur dengan alat surface roughness tester dan dievaluasi melalui analisis statistik, One-Way ANOVA dan Post-Hoc LSD. Hasil : Rerata selisih pretest - posttest kelompok I, II, III, dan kontrol sebesar 0,056, 0,094, 0,167, dan 0,008 μm. Hasil tersebut menunjukkan adanya perbedaan kekasaran permukaan GIC yang signifikan (p <0,05), dengan variasi antara semua kelompok. Simpulan: Peningkatan jumlah hisapan rokok kretek non-filter dapat meningkatkan kekasaran permukaan GIC konvensional.
THE RELATIONSHIP BETWEEN THE MARKETING MIX OF MOBILE DENTAL SERVICES AND THE INTEREST IN REPEAT VISITS BY PATIENTS AT THE DENTAL HOSPITAL OF JENDERAL SOEDIRMAN UNIVERSITY Mudrikah, Tania Salsa Belani; Prakosa, Aditya Priagung; Kumala, Lukita Intan; Cahyani, Inneke; Widyaningsih, Pratiwi Nur
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Vol. 12 No. 2 (2025): Vol 12 No 2 (December 2025)
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v12i2.1867

Abstract

Introduction: Educational Dental Hospital of Jenderal Soedirman Purwokerto has been facing problems regarding patient visit numbers in recent years. Evaluation of the marketing using mobile dental services is necessary to determine how effective the service is. One of the strategic efforts made is to use the marketing mix concept, which consists of 7 components: product, price, place, promotion, people, process, and physical evidence. Aim: This study aims to understand the correlation between the marketing mix of mobile dental services and patient revisit interest at the Educational Dental Hospital of Jenderal Soedirman University. Method: The research used an observational analytical design with a cross-sectional approach. The sample taken for this study consists of 52 individuals using a total sampling technique. This research instrument uses a questionnaire on the marketing mix of dental mobile car, and a questionnaire on interest in repeat visits, distributed to respondents. Data were analyzed using Univariate and Bivariate analysis with Fisher’s Exact Test. Results: The results of this study indicate that there is a significant relationship between the marketing mix factors of product (p=0.016) and promotion (p=0.010). However, there is no significant relationship between the marketing mix factors of price (p=0.245), place (p=0.221), people (p=0.110), process (p=0.129), and physical evidence (p=0.481) with patient revisit interest at the Educational Dental Hospital of Jenderal Soedirman University. Conclusion: This research recommends that RSGMP Unsoed improve and optimize the factors of price, place, people, process, and physical evidence in order to increase the interest of patients to visit again.
Co-Authors Adhela Salsabila H Aldina G Aldina G Amalia Putri Hesantera Anggraeni, Nova Dwi Aniowati, Fitri Annisa Sukma Visanda Aprillya Yuniarni Arina Manasikana Eska Artanti, Evania Bellinda Artha Arum P Asyyfa Devy Ayu Intan Nur A Bimantoro, Muhammad Satriyo Cahyani, Inneke Cantika Nadrotan Naim Cantika Nadrotan Naim Dani Intan Prabawati Desi Rachmawati DEWI RAHMAWATI Dian Noviyanti Dicky Satria Ramadhan Basar Diva Sascha P Dwi Cinthya Financia Elisabeth Lorna Dona Erlina Sih Mahanani, Erlina Sih Fani Tuti Handayani, Fani Tuti Fitranto Arjadi Fitranto Arjadi Fitri Aniowati Fitri Aniowati Ghaida Humaira Susilo Putri Haidy Lailatun Nabila Hanifah Nur Syafa Haryani Devi R Helmi Hirawan Husni Rama Wijayanti Irfan Dwiandhono Irfan Dwiandhono Irfan Dwiandhono Kumala, Lukita Intan Kunthi Isri Wulandari Kurniawan, Aris Aji Laksitasari, Anindita Licha Permata S Luqman Mahadika Cahyono Milla, Dzhofirotul Minda Anita Mudrikah, Tania Salsa Belani Mutia Rochmawati Nabilah Annisa R Nadya Elsa Cahyaningrum Nadya Hanan S Nadya Loverina G.P Nahya, Bintan Naila Robbaniyya Fithriyya Naim, Cantika Nadrotan Nisa Aqila Zulfa Nova Dwi Anggraeni Nova Dwi Anggraeni Nur Faizah Zahirah Nurul Hasanah Tanjung Prakosa, Aditya Priagung Purnama, Ryana Budi Raihan Zachary Ramadhan Raja Ronaldo Siregar Rakhmawati Rakhmawati Rakhmawati Rakhmawati Ridha Nur A Rinawati Satrio Riski Amalia Hidayah Ryana Budi Purnama Ryana Budi Purnama Ryana Budi Purnama Sabrina Aulia Nurul Hidayah Salma Kaltsum Kayana Salwa Az-Zahra Septina Nur Aini Setyah Sultrasari D Shabrina Nur Zahra S Shahnaz Dwi Permata Putri Tirta Wardana Tirta Wardana Tirta Wardana Tirta Wardhana Yunita K Yunita K