Claim Missing Document
Check
Articles

Found 17 Documents
Search

Efficacy of Putri Malu Leaf Plant (Mimosa Pudica Linn) as Hepatoprotectors on Ibuprofen Induced Hepatic Damage in White Mice (Mus Musculus) Bagaskara, Andre; Triastuti, Nenny; Yuliyanasari, Nurma; Annisa Ayu Rezkitha, Yudith; Anas, Muhammad; Indra Alfaray, Ricky
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 9, No 1 (2022): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.9.1.2022.01-09

Abstract

Background:Putri Malu plants (Mimosa pudica linn) contain flavonoid compounds that are useful as hepatoprotectors. Putri Malu plants extract can be usefull to prevent problem such as Ibuprofen-induced hepatic damage., but study that focus on this topic remain scarce in Indonesia. Objective: To prove the extracted content of the leaves of the Putri Malu plant (Mimosa pudica linn) as a hepatoprotector of hepatic damage in mice (Mus musculus) induced by Ibuprofen. Method: This randomized post-test control group design was conducted at the Experimental Animal Laboratory, Faculty of Veterinary Medicine, Universitas Airlangga. A total of 28 mice were treated with four condition then underwent SGOT and SGPT blood laboratory tests. Results: Group P1 (placebo) had SGOT and SGPT levels averaging 23.87 mg/dl and 13.45 mg/dl, group P2 (ibuprofen dose 7 mg/KgBW) had SGOT and SGPT levels of 29.13 mg/dl and 19.10 mg/dl, group 3 (Putri Malu extract 35 mg/KgBW) had SGOT and SGPT of 24.05 mg/dl and 13.56 mg/dl, and group 4 (ibuprofen dose 7 mg/KgBW and Putri Malu extract of 35 mg/KgBW) showed SGOT and SGPT levels of 28.23 mg/dl and 18.35 mg/dl. The four groups had different mean SGOT and SGPT levels (P 0,000). Conclusion:Leaf extract of the Putri Malu plants (Mimosa pudica linn) has a chemical effect of heaptoprotector as shown by the decrease in SGOT and SGPT level.
THE ELEVATION OF OSTEOBLAST ACTIVITY IN RAT BONE MARROW MESENCHYMAL STEM CELLS IN OSTEOGENIC MEDIUM EXPOSED WITH MELATONIN IN PHYSIOLOGICAL DOSES Yuliyanasari, Nurma; Mastutik, Gondo; Putra, Suhartono Taat
Folia Medica Indonesiana Vol. 53 No. 1 (2017): JANUARY - MARCH 2017
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (629.275 KB) | DOI: 10.20473/fmi.v53i1.5489

Abstract

The objective of this study was to analyze the elevation of osteoblast activity in bone marrow mesenchymal stem cells (BM-MSCs) in osteogenic medium by physiological doses of melatonin administration by measuring alkaline phosphatase (ALP) and osteocalcin level.This studyused BM-MSCs from Rattusnorvegiccus femur bone. Rat BM-MSCs were cultured in a-Mem medium, differentiated in osteogenic medium, and administrated melatonin up to 21 days. This study was divided into 4 groups, K0 (control group), K1 (administrated of 25 nM melatonin), K2 (administrated of 50 nM melatonin), and K3 (administrated of 100 nM melatonin). Rat BM-MSCs were characterized CD 45- and CD 105+ marker using imunocytochemistry analysis and stained with Alizarin red after 15 days treatment. ALP and osteocalcin level were measured using ELISA Kit in days 21st.There weren't differences ofALP level beetwen groups and there are differences ofosteocalcin level between control groups (K0) withK1, K2, dan K3, and beetwen K1 and K2. The conclusion of this study was that there were an elevation of osteoblast activity in rat BM-MSCs in osteogenic medium by physiological doses of melatonin administration characterized by the elevation of osteocalcin level.
The Influence of Learning Video Media On Protocol Health Knowledge Covid-19 Elementary School Students Pipit Festi Wiliyanarti; Nurma Yuliyanasari; Badruli Martati
STRADA : Jurnal Ilmiah Kesehatan Vol. 10 No. 1 (2021): May
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjik.v10i1.617

Abstract

High Prevalence covid 19 school-age children to be a problem throughout the world, including Indonesia. Increasing children's knowledge through learning media is expected to be easily accepted so that the implementation of protocols can be implemented by child. The purpose of this study was to analyze the effect of instructional video media on the knowledge of Covid health protocol. This is a pre- experimental study, useda static group comparison design approach. Sampleof study consisted of the treatment groups are primary school age children are 24 people, the group that did not receive treatment as many as 30 children by purposive sampling. Analysts use in dependent T test, α=0.05. There was an effect of instructional video media on the knowledge of covid health protocol for 19 elementary school students with a sig result of 0.00. Learning using video media can increase the knowledge of elementary school students in implementing health protocols.
PERAN FUN GAMES TERHADAP FUNGSI KOGNITIF DAN KEMATANGAN EMOSIONAL PADA SISWA SD MUHAMMADIYAH 18 SURABAYA Gina Noor Djalilah; Yelvi Levani; Laily Irfana; Nurma Yuliyanasari; Nenny Triastuti
DedikasiMU : Journal of Community Service Vol. 7 No. 2 (2025): DedikasiMU Juni
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/dedikasimu.v7i2.9920

Abstract

Perkembangan anak usia sekolah dasar merupakan tahap penting dalam pembentukan berbagai aspek psikologis, terutama fungsi kognitif dan kematangan emosional. Kegiatan Pengabdian kepada Masyarakat (Abdimas) ini bertujuan mengimplementasikan dan mengevaluasi pengaruh fun games terhadap fungsi kognitif dan kematangan emosional siswa kelas 2 SD Muhammadiyah 18. Metode pelaksanaan dalam kegiatan pengabdian kepada masyarakat ini adalah sebagai berikut: Penyuluhan kesehatan untuk orang tua siswa SD Muhammadiyah 18 Surabaya dan kegiatan fun games untuk siswa SD Muhammadiyah 18 Surabaya. Kegiatan fun games yang diadakan untuk siswa SD Muhammadiyah 18 Surabaya diantaranya adalah: Permainan Puzzle, Permainan Ular Naga, Permainan Match Matching, Permainan Picture Memory, Permainan Lambang Bilangan dan Permainan Clap Boom Snatch. Dari hasil kegiatan pengabdian masyarakat ini ditemukan skor fungsi kognitif yang secara keseluruhan baik. Melalui kegiatan abdimas ini, diharapkan terjadi peningkatan kemampuan berpikir dan kecerdasan emosional siswa SD Muhammadiyah 18 secara simultan.
THE RELATIONSHIP BETWEEN BLOOD PRESSURE LEVELS AND THE INCIDENCE OF DIABETIC NEUROPATHY IN TYPE-2 DIABETES MELLITUS PATIENTS. Indriyani, Putri; Yuliyanasari, Nurma; Kartikasari, Irma; Irfana, Laily
Biomedika Vol 17, No 1 (2025): Biomedika August 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i2.11121

Abstract

Diabetic neuropathy (DN) is microvascular complications in people with type 2 diabetes that can significantly affect patients’ quality of life. Higher levels of blood pressure are known to be associated with an increased occurrence of diabetic neuropathy in type 2 diabetes patients. This study aimed to determine the risk factors for blood pressure levels with the incidence of diabetic neuropathy. This approach used purposive sampling with a cross-sectional methodology. SPSS version 26 with the chi square test was used to analyze the data. This study involved 68 patient. Patient with diabetic neuropathy mostly female (23.8%), aged of 51-60 years (16.2%), have had diabetes for > 5 years (22.1%), consumed insulin or anti-diabetic medications orally (35.5%), have a history of hypertension (20.6%), and do not take antihypertensive drugs (20.6%). ccording to the findings of the ci-squre analysis, there was a significant correlation between the incidence of diabetic neuropathy and the level of blood pressure (p < 0.04). Patients who suffer from neuropathy diabetic had the most hypertension grade 1. Meanwhile, patients who do not had diabetic neuropathy mostly have optimal, normal and normal-high blood pressure. In conclusion, there is a correlation between the incidence of blood pressure levels and diabetic neuropathy.
HUBUNGAN AKTIVITAS FISIK DAN OBESITAS DENGAN KOMPLIKASI ULKUS DIABETIK PADA PASIEN DIABETES MELITUS TIPE 2 DI RUMAH SAKIT PETROKIMIA GRESIK DRIYOREJO Irawati , Detti Nur; Yuliyanasari, Nurma; Sari , Dyah Maya
JurnalMU: Jurnal Medis Umum Vol 1 No 1 (2024): Jurnal Medis Umum
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmu.v1i01.21575

Abstract

Latar Belakang : Diabetes melitus merupakan suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin atau keduanya. Hiperglikemia yang terjadi dalam kurun waktu lama dan tidak terkontrol dapat menyebabkan kerusakan pada sistem tubuh khususnya sistem saraf dan pembuluh darah. Hal inilah yang dapat memicu terjadinya ulkus diabetik. Komplikasi ulkus diabetik pada penderita diabetes melitus tipe 2 dapat terjadi karena adanya neuropati, iskemik, dan kemudian adanya infeksi. Terdapat beberapa faktor yang dapat dimodifikasi diantaranya adalah aktivitas fisik dan obesitas. Tujuan: Untuk mengetahui hubungan antara aktivitas fisik dan obesitas dengan komplikasi ulkus diabetik pada pasien diabetes melitus tipe 2 di Rumah Sakit Petrokimia Gresik Driyorejo. Metode : Penelitian ini termasuk ke dalam penelitian observasional analitik dengan dengan pendekatan cross sectional. Responden dipilih dengan teknik Non Probability Sampling dengan tipe Purposive Sampling. Dilakukan dengan mengumpulkan data menggunakan kuisoner dan pemeriksaan berat badan dan tinggi badan pada pasien diabetes mellitus yang di rawat jalan dan inap di Rumah Sakit Petrokimia Gresik Driyorejo periode September-November 2022. Data dianalisis menggunakan uji korelasi koefisien kontingensi. Hasil : Hasil uji korelasi koefisien kontingensi aktivitas fisik dan obesitas dengan komplikasi ulkus diabetik pada pasien diabetes melitus tipe 2 di Rumah Sakit Petrokimia Gresik Driyorejo diperoleh p value < 0,05. Kesimpulan : Terdapat hubungan antara aktivitas fisik dan obesitas dengan komplikasi ulkus diabetik pada diabetes melitus tipe 2 di Rumah Sakit Petrokimia Gresik Driyorejo.
Hubungan Kebiasaan Sarapan dengan Prestasi Belajar Anak Sekolah Dasar Muhammadiyah 6 Gadung Surabaya Nugraha, Adi Satria; Djalilah, Gina Noor; Yuliyanasari, Nurma; Rezkitha, Yudith
JurnalMU: Jurnal Medis Umum Vol 1 No 2 (2024): Jurnal Medis Umum
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmu.v2i02.23043

Abstract

Latar Belakang: Kebutuhan makronutrien pada anak Indonesia masih kurang (<20% AKG Harian) pada asupan energi, karbohidrat, dan lemak. Sarapan yang berkualitas dengan kandungan gizi yang seimbang dan memenuhi 20-35% dari kebutuhan energi total yang dikonsumsi pada pagi hari merupakan hal yang penting bagi anak untuk mendukung kegiatan belajar di sekolah. Sarapan memiliki hubungan yang signifikan terhadap proses kecepatan berpikir dan ketelitian. Tujuan: Mengetahui hubungan kebiasaan sarapan dengan prestasi belajar anak sekolah dasar muhammadiyah 6 gadung surabaya. Metode: Jenis penelitian ini yaitu analitik observasional dengan desain cross sectional study. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah teknik non probability dengan jenis sampling yaitu consecutive. Penelitian ini menggunakan kuesioner online dalam bentuk Google Form untuk mengumpulkan data dan analisis data yang digunakan adalah uji eta. Hasil: Hasil uji eta hubungan kebiasaan sarapan dengan prestasi belajar didapatkan nilai Fhitung < Ftabel. Kesimpulan: Tidak terdapat hubungan antara kebiasaan sarapan dengan prestasi belajar