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All Journal As-syifaa Jurnal Farmasi GANEC SWARA INTEK: Jurnal Penelitian Jurnal Gema Ngabdi Elastisitas Jurnal Ekonomi Pembangunan Jurnal Abdimas Sangkabira Agrimansion: Agribusiness Management & Extension KNOWLEDGE: Jurnal Inovasi Hasil Penelitian dan Pengembangan Seminar Nasional Pengabdian Kepada Masyarakat Pharmaceutical Reports Business Management Jurnal Konstanta : Ekonomi Pembangunan Journal Microbiology Science West Science Business and Management West Science Journal Economic and Entrepreneurship West Science Interdisciplinary Studies Jurnal Oportunitas : Ekonomi Pembangunan West Science Interdisciplinary Studies MPSJ Cognitive
St. Maryam, St.
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ANALISIS KANDUNGAN SENYAWA FENOLIK DAN TANIN PADA ISOLA FUNGI ENDOFIT (IFEBK20) BUNGA KERSEN (Muntingia calabura L) DENGAN METODE SPEKTROFOTOMETRI UV-VIS p, irmawan jamal; Maryam, St.; Suhaenah, Asriani
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.33

Abstract

Bunga Kersen (Muntingia calabura L.) mengandung fungi endofit yang mampu menghasilkan metabolit sekunder yang sama dengan sel inangnya, dimana metabolit sekunder ini dari isolat fungi endofit IFEBK20 seperti senyawa fenol dan tanin yang merupakan kelompok senyawa fenolik terbesar. Pada penelitian ini bertujuan untuk mengetahui berapa kadar senyawa fenolik dan tanin yang dihasilkan dari isolat fungi endofit bunga kersen (Muntingia calabura L.) secara kuantitatif menggunakan metode spektrofotometri UV-Vis. Dari hasil penelitian menunjukkan bahwa ekstrak isolat IFEBK20 bunga kersen (Muntingia calabura L.) mengandung senyawa fenol dan tanin. Secara kuantitatif ekstrak isolat IFEBK20 bunga kersen (Muntingia calabura L.) diukur pada panjang gelombang maksimum 739,901 nm untuk fenol dengan baku pembanding asam galat, dan diukur pada panjang gelombang maksimum 738,578 nm untuk tanin dengan baku pembanding asam tanat. Hasil penelitian menunjukkan bahwa kadar rata-rata ekstrak isolate IFEBK20 bunga kersen (Muntingia calabura L.) mengandung senyawa fenol sebesar 21,447 mgGAE/g ekstrak atau 2,144 % b/b GAE, dan senyawa tanin sebesar 31,584 mgTAE/g ekstrak atau 3,158 %
AKTIVITAS INHIBISI ENZIM ALFA-GLUKOSIDASE DARI EKSTRAK BUNGA KERSEN (Muntingia calabura L.) SECARA IN VITRO Azzahra, Resqinah; Maryam, St.; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i3.80

Abstract

The cherry tree is one of the plants that has great potential to be utilized because it contains several beneficial bioactive compounds, one of which is flavonoids.. The purpose of this research is to determine the alpha-glucosidase enzyme inhibition activity of an ethanol extract of cherry blossoms (Muntingia calabura L.) in vitro using a microplate reader instrument. The research method begins with preparing the sample by maceration using 96% ethanol as a solvent, followed by testing the inhibition of alpha-glucosidase enzyme activity using p-nitrophenyl- α-D-glucopyranoside (PNPG) substrate and acarbose as a comparison. The potential of a compound to inhibit enzyme activity can be determined by calculating the IC50. The results showed that the ethanol extract of cherry blossoms (Muntingia calabura L.) has an IC50 value of 135.53 µg/mL, higher than the IC50 value of acarbose at 41.17 µg/mL.
Identifikasi Gugus Fungsi Limbah Minyak Trafo yang Digunakan sebagai Minyak Obat Luka Menggunakan FTIR Hidayanti, Nurul; Rahmawati, Rahmawati; Maryam, St.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.92

Abstract

Communities living close to PLN empirically use waste transformer oil as a medicine for wounds such as cuts or cuts and burns such as being exposed to oil or hot cooking utensils. Transformer oil has the main function as an insulating medium and as a coolant. This study aims to determine the chemical components contained in transformer oil waste by using FTIR. The results of research on transformer oil waste using the FTIR method showed that there were carboxyl functional groups, amide groups, aromatic rings, nitro groups and alkyl groups.
ANTIOXIDANT ACTIVITY TEST OF THE ETHANOL EXTRACT OF AVOCADO SEED (Persea americana Mill.) USING THE FRAP METHOD Ohorela, Indah Kartika; Maryam, St.; Suhaenah, Asriani
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.221

Abstract

Avocado seeds (Persea americana Mill.) are a plant that is useful as a traditional medicine. The ethanol extract of avocado seeds contains several secondary metabolite compounds, namely alkaloids, triterpenoids, tannins, flavonoids and saponins. The aim of this research was to determine the antioxidant activity contained in avocado seed extract (Persea americana Mill.). using the FRAP method which was measured with a UV-Vis spectrophotometer at a wavelength of 794 nm. Extraction of avocado seeds (Persea americana Mill.) using the maceration method using 96% ethanol solvent. The results show that the antioxidant activity of the ethanol extract of Avocado Seeds is 42.448 mgQE/g of extract, which means that every 1 gram of ethanol extract of avocado seeds (Persea americana Mill.) is equivalent to 42,488 mg of quercetin.
Analisis Kadar Senyawa Polifenol Dari Teh Daun Tanaman Cacao (Theobroma cacao L.) Secara Spektrofotometri UV-Vis Desi, Nilma Sri; Maryam, St.; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.242

Abstract

. Cocoa leaves (Theobroma cacao L.) contain secondary metabolites such as polyphenol compounds, flavanoids, saponins and tannins which are the largest group of phenolic compounds that act as antioxidant compounds. This study aims to determine the levels of polyphenolic compounds produced from cocoa leaf tea preparations (Theobroma cacao L.) based on the comparison of growing places, namely the Wajo, Jeneponto and Malino regions. Quantitative analysis using UV-Vis spectrophotometric method. based on qualitative analysis by Thin Layer Chromatography method using mobile phase n- hexanes: ethyl acetate: methanol with a ratio (2: 7: 2). Based on the results showed that the preparation of cocoa leaf tea (Theobroma cacao L.). As well as quantitative analysis measured at a maximum wavelength of 768 nm with gallic acid comparator standard. Tea samples contain polyphenolic compounds based on the Rf value equivalent to gallic acid comparator of 0.6. based on the analysis of levels from the Wajo area of 16.238 mgGAE/g, Jeneponto area 18.102 mg/GAE/g, and Malino area 6, 752 mgGAE/g and rf value of gallic acid comparator 0.630; rf value of samples from Jeneponto area 0.6; Wajo 0.6 and Malino 0.615. From the above results, it can be concluded that there are polyphenol compounds in tea samples from each region and the largest polyphenol content is found in the Jeneponto area.
Analisis aktivitas perlindungan sinar UV ekstrak etanol daun kakao (Theobroma cacao L.) berdasarkan nilai Sun Protection Factor. Rustam, Julis Tina; Maryam, St.; Suhaenah, Asriani
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.243

Abstract

UV rays have a bad impact on the skin, but they can be minimized by using ingredients that are UV protective. Sunscreen can be obtained from natural ingredients, one of which is Cocoa Leaves (Theobroma cacao L.) which contains flavonoid and phenolic compounds. The aim of this research was to determine the UV protection activity of ethanol extract of cocoa leaves (Theobroma cacao L.) originating from the Malino, Jeneponto and Wajo areas based on the Sun Protection Factor value. Measurement of the Sun Protection Factor (SPF) value using the UV-Vis Spectrometry method was measured at wavelengths of 290, 295, 300, 305, 310, 315 and 320 nm. The results showed that the ethanol extract of cocoa leaves (Theobroma cacao L.) had UV protection activity for the Malino area at a concentration of 0.01% of 3.25 (minimum protection), a concentration of 0.03% of 10.34 (maximum protection). , 0.05% concentration of 17.10 (ultra protection). For the Jeneponto area, the 0.01% concentration is 3.88 (minimum protection), the 0.03% concentration is 12.3 (maximum protection), the 0.05% concentration is 20.18 (ultra protection) and the Wajo area has a value at a concentration of 0.01% it is 3.38 (minimum protection), a concentration of 0.03% is 10.77 (maximum protection), a concentration of 0.05% is 17.05 (ultra protection). Ethanol extract of cocoa leaves (Theobroma cacao L.) originating from Jeneponto has the greatest UV protection activity with a value of 20.18 with ultra protection ability.
AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL RIMPANG KUNYIT (Curcuma domestica Val.) SECARA IN VITRO RAHMAN, ANDI AMALIA RAMADHANI; Maryam, St.; Razak, Rais
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.247

Abstract

Kunyit merupakan salah satu tanaman rempah-rempah yang memiliki berbagai aktivitas farmakologis. Rimpang kunyit (Curcuma domestica Val.) mengandung kurkumin dan minyak atsiri yang bermanfaat sebagai antioksidan, antiinflamasi, dan antibakteri. Tujuan penelitian ini yaitu untuk mengetahui potensi rimpang kunyit sebagai antiinflamasi secara in vitro menggunakan metode penghambatan denaturasi protein. Penggunaan metode ini karena salah satu penyebab inflamasi adalah terjadinya denaturasi protein pada jaringan sel tubuh. Hasil uji berupa persentase inhibisi dengan nilai 38,38% pada konsentrasi 10 ppm hingga 46,51% pada konsentrasi 50 ppm. Persentase inhibisi >20% menunjukkan bahwa ekstrak dapat menghambat denaturasi protein. Perhitungan IC50 menunjukkan nilai sebesar 46,87 μg/mL. Sehingga dapat disimpulkan bahwa ekstrak etanol 96% rimpang kunyit memiliki potensi sebagai antiinflamasi.
UJI AKTIVITAS ANTIOKSIDAN DARI TEH DAUN TANAMAN KAKAO (Theobroma cacao L.) BERDASARKAN TEMPAT TUMBUH DENGAN METODE PEREDAMAN RADIKAL BEBAS DPPH Syam, Nurizzah Aulia; Maryam, St.; Baits, Muzakkir
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.267

Abstract

Tanaman kakao merupakan salah satu tanaman yang digunakan oleh masyarakat sebagai obat tradisional. Daun tanaman kakao mengandung metabolit sekunder yaitu flavonoid,saponin dan tanin serta mengandung senyawa fenolat, yang juga memiliki peran sebagai antioksidan. Tujuan dari penelitian ini untuk mengetahui aktivitas antioksidan dan menganalisa IC50 dari teh daun tanaman kakao (Theobroma cacao L.) dengan menggunakan metode DPPH (2,2-difenil-1-pikrilhidrazil). Sampel yang digunakan berasal dari tiga daerah yaitu Jeneponto, Wajo, dan Malino. Berdasarkan hasil penelitian, menunjukkan bahwa sediaan teh daun kakao (Theobroma cacao L.) memiliki aktivitas sebagai antioksidan. Nilai IC50 sediaan teh daun kakao (Theobroma cacao L.) Jeneponto sebesar 187,946 µg/mL, Wajo 309,629 µg/mL, dan Malino sebesar 314,055 µg/mL dengan kategori klasifikasi sangat lemah. Sediaan teh daerah Jeneponto memiliki aktivitas antioksidan yang lebih baik dari dua daerah lainnya. Kata kunci: Antioksidan, DPPH (2,2-difenil-1-pikrilhidrazil), Theobroma cacao L., Kuarsetin.
UJI AKTIVITAS ANTIOKSIDAN PADA EKSTRAK ETANOL DAUN KAKAO (Theobroma cacao L.) DENGAN PERBANDINGAN BERDASARKAN TEMPAT TUMBUH DENGAN METODE PEREDAMAN RADIKAL BEBAS DPPH Salahuddin, Muthia Amaliah; Maryam, St.; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.268

Abstract

Kakao (Theobroma cacao L.) merupakan salah satu tanaman yang mengandung senyawa metabolit sekunder yaitu flavonoid, saponin dan tanin. Secara empiris daun kakao digunakan sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan ekstrak etanol daun kakao (Theobroma cacao L.) dengan perbandingan berdasarkan tempat tumbuh menggunakan metode peredaman radikal bebas DPPH (2,2-Difenil-1-Pikrilhidrazil) dengan parameter nilai IC50. Berdasarkan hasil yang diperoleh, hasil uji kualitatif menunjukkan adanya metabolit sekunder yang terkandung dalam esktrak etanol daun kakao seperti alkaloid, fenolik, flavonoid, saponin, dan tanin serta diperoleh nilai IC50 ekstrak etanol daun kakao daerah Jeneponto sebesar 24,658 µg/mL kategori sangat kuat, daerah Malino 59,742 µg/mL kategori kuat, serta Wajo 56,898 µg /mL kategori kuat dengan perbandingan baku pembanding yaitu kuersetin dengan nilai IC50 sebesar 1,882 µg/mL kategori sangat kuat. keyword: Theobroma cacao L., antioksidan, IC50;
Antioxidant Activity Aktivitas Antioksidan Ekstrak Etanol Daun Lerak (Sapindus rarak DC) Dengan Metode Peredaman Radikal Bebas DPPH Asri, Fitriani; Suhaenah, Asriani; Maryam, St.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.289

Abstract

FITRIANI ASRI. Antioxidant Activity Of Ethanol Extract Of Lerak eaves (Sapindus rarak) Using The DPPH Free Radical Reduction Method (Supervised by Asriani Suhaenah dan St. Maryam) Lerak leaves (Sapindus rarak) are a traditional plant used by the community to treat various diseases. The secondary metabolic compounds contained in the lerak plant (Sapindus rarak) which have potential as antioxidants are flavonoids, alkaloids, saponins, tannins, quinones, steroids and triterpenoids which are obtained through extraction using ethanol solvent. This research aims to determine the antioxidant activity of the ethanol extract of lerak leaves (Sapindus rarak) using the DPPH free radical reduction method (1,1-diphenyl-2-picrihydrazyl). The antioxidant value was measured using UV-Vis spectrophotometry at a wavelength of 516 nm. The calculation results show an IC50 value of 876,592 μg/mL (very weak category) while quercetin as a comparison has very strong antioxidant activity with an IC50 value of 1,882 μg/mL.
Co-Authors A. Muflihunna, A. Agustiani, Eka Agustin, Verren Regina Akung Daeng Alodya, Baiq Putri amelia yolanda, amelia Aminah Aminah Annisa, Nurfiqah arifin, nurrizky afiah Arini, Gusti Ayu Asri, Fitriani Asriani Suhaenah Azzahra, Resqinah B, Moh Baktiar Desi, Nilma Sri EMI SALMAH Fajar, Suwandy Fitriana Fitriana Fuady, Helmi Hidayanti, Nurul Hidayat, M. Ali Akbar Indriyani , Maulida Irwan Irwan Irwan, M Irwan Iwan Harsono Khoirul Umam Lambang Basri Said M. Firmansyah M. Irwan M. Irwan, M. Irwan Masdiana Tahir, Masdiana Mayanah, Dewi Muhammad Awaludin Muhammad Firmansyah, Muhammad Mustika, Nurfadila Muzakkir Baits, Muzakkir Nur Awwalunnisa, Nur Ohorela, Indah Kartika p, irmawan jamal Parobi, Rizki Prima Astuti Handayani Putra, Iwan RAHMAN, ANDI AMALIA RAMADHANI Rahmawati, Rahmawati Rais Razak, Rais Ramdani, Ridho Rekhan. T, Muh Rafli Rusniyanti, Rusniyanti Rustam, Julis Tina Sahri Sahri Salahuddin, Muthia Amaliah Salim, Medina Sasliani, Sasliani Satarudin Siti Helmyati Syam, Nurizzah Aulia Sya’baniyah Herman, Nur Fajriah Wahidin Wahidin Wahyudi, M. Ilham Wiwik Handayani