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All Journal VALENSI JURNAL KIMIA SAINS DAN APLIKASI Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) KOVALEN: Jurnal Riset Kimia Jurnal Kesehatan Bakti Tunas Husada JMM (Jurnal Masyarakat Mandiri) Chemistry Indonesian Journal of Chemical Research JFL : Jurnal Farmasi Lampung PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Kreativitas PKM Molekul: Jurnal Ilmiah Kimia Kumawula: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Farmako Bahari Molekul: Jurnal Ilmiah Kimia Jurnal Pengabdian Masyarakat (Jupemas) Jurnal Kesehatan Bakti Tunas Husada Jurnal Farmasi Galenika
Winda Trisna Wulandari, Winda Trisna
Universitas Bakti Tunas Husada
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : JURNAL KIMIA SAINS DAN APLIKASI

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Utilization of Jengkol Peel (Pithecellobium jiringa (Jack) Prain) as Lead (II) Ions Bio-sorbent with Column Method Gatut Ari Wardani; Lia Nuramalia; Winda Trisna Wulandari; Estin Nofiyanti
Jurnal Kimia Sains dan Aplikasi Vol 23, No 5 (2020): Volume 23 Issue 5 Year 2020
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2637.893 KB) | DOI: 10.14710/jksa.23.5.160-166

Abstract

Problems arising from laboratory waste include the content of lead metal ions in it, which can affect health. While on the other hand, Jengkol peel is a market waste and has no economic value. Jengkol peel contains hydroxyl groups and carboxylates to bind heavy metals such as lead (II) ions. So, this study aims to determine the effect of variations in flow rate, adsorbent height, and solution acidity and determine the ability of Jengkol peel in adsorbing lead (II) ions in the laboratory liquid by the column method. Organic groups that include active sides can be removed using 1N sodium hydroxide to increase the adsorption ability. Sodium hydroxide functions to dissolve lignin in lignocellulose compounds so that carboxylic groups are formed in cellulose, which has a role in binding metal ions. The determination of functional groups was carried out by Fourier-transform Infrared Spectroscopy. The identification of the adsorbent morphology was carried out by Scanning Electron Microscope. The adsorption of lead (II) ions by Jengkol peel was determined by calculating the difference between the lead (II) ions in the solution after and before passing through the column. The amount of lead metal remaining in solution was determined using Atomic Absorption Spectroscopy. Sodium hydroxide solution with a concentration of 1N can separate lignin from cellulose contained in lignocellulose to enhance the bio-sorbent ability of the Jengkol peel in binding metal ions. The smaller the flow rate in the column, the higher the amount of lead (II) ions adsorbed in the bio-sorbent. The acidity of the solution has the best adsorption at pH 5. The metal ions from the simulation sample can reduce the number of lead (II) metal ions adsorbed by 11%.
Synthesis, Characterization and Molecular Docking of Bis-(1-(2,4-dichlorobenzoyl)-3-methylthiourea) Iron (III) Complex as Anticancer Candidate Ruswanto Ruswanto; Feri Sandria; Winda Trisna Wulandari; Richa Mardianingrum
Jurnal Kimia Sains dan Aplikasi Vol 27, No 6 (2024): Volume 27 Issue 6 Year 2024
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.27.6.258-264

Abstract

The Bis-(1-(2,4-dichlorobenzoyl)-3-methylthiourea) iron (III) complex has been synthesized from the reaction between 1-(2,4-dichlorobenzoyl)-3-methylthiourea and Fe (III) metal ion by reflux method with ethanol solvent at a temperature of 75°C for 7 hours. It was characterized by a hot stage microscope (HSM), UV-Vis, FT-IR, and mass spectroscopy. The % yield of the synthesis result was 97.58%. From the docking study on the ribonucleotide reductase enzyme, the binding affinity value was -7.76 kcal/mol, and the inhibition constant was 2.11 mM. The Bis-(1-(2,4-dichlorobenzoyl)-3 methylthiourea) iron (III) complex compounds can be synthesized and predicted as anticancer candidates.
Co-Authors Ade Putri Suci Lestari Ade Yeni Ade Yeni Aprilia Ade Yeni Apriliani Ade Yeni Aprillia Ade Yeni Aprillia Alhikam Nazabullah Alma Meidina Anindita Tri Kusuma Pratita Anna Yuliana, Anna Annissya, Widia Primi Aprillia, Ade Yeni Arya Purba Wasana Augie, Andrea Ayu Geamul Maskur Bagas Pra Ramdani Cahyati, Keni Ida Cucu Nurpatonah Dea Dara Pamungkas Diana Sri Zustika Diana Sri Zustika, Diana Sri Dina Lestari Eka Yuniarti Estin Nofiyanti Estin Nofiyanti Fabillah Kurniadi Fajar Setiawan FAJAR SETIAWAN Fajar Setiawan Fajar Setiawan Fajar Setiawan Febby Pratama Feri Sandria Firman Gustaman Firman Gustaman Firman Gustaman Firman Gustaman Firman Gustaman Firman Gustaman Firmansya, Ardianes Fujianti Putri Nuraisah Gatut Ari Wardani Gatut Ari Wardhani Gina Nur Fitria Mulyana Putri Gustaman, Firman Hanna Nurul Husna Hanna Nurul Husna Hanna Nurul Husna Hisni Nurul Fajri Idacahyati, Keni Indah Alvina Damayanti Indah Cantika Indra Indra Indra Indra Indra, Indra Intan Gita Cahyani Itmam Milataka Julyanti, Ai Rian Keni Ida Cahyani Keni Idacahyati Keni Idacahyati Keni Idacahyati Keni Idacahyati Keni Idacahyati Laras Rizkia Widyastuti Lia Nuramalia Lilis Tuslinah Lilis Tuslinah Lilis Tuslinah Lilis tuslinah Lusi Nurdianti, Lusi Maolana, Ananda Meri Meri Meri, Meri Muhtar, Muhammad Wildan Mulya Tri Sugiharti Nur Laili Dwi Hidayati Nur Rahayuningsih, Nur Nurfadhilla, Dilla Nurfaiza Safitri Nurhidah, Mia Nurmalasari, Anisa Nurzaman Raras, Euis Reza Ariza Wildan Richa Mardianingrum Rijkiyah, Gina Sheli Rizky Nur Alam Rosmaya Dewi Rosmaya Dewi Ruswanto Ruswanto Ruswanto, Ruswanto Silvia Rahmawati Sugiharti, Mulya Tri Syahputra, Ricky Andi Taofik Hidayat Taufik Hidayat Tresna Lestari, Tresna Vera Nurviana Wawan rismawan Wawan Rismawan Widiyanti Widiyanti Yassinqi, Manita Cenda Zahrotun Naqiah Zain, Dichy Nuryadin Zakia Nurul Izzah