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All Journal Jurnal Farmasi Klinik Indonesia Jurnal Farmasi Sains dan Komunitas Jurnal Kesehatan Bakti Tunas Husada SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Indonesian Journal of Medicine Jurnal Farmasi Indonesia Jurnal Ilmu Kefarmasian Indonesia Health Sciences and Pharmacy Journal Majalah Farmasetika Pharmacoscript Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat INDRA: Jurnal Pengabdian kepada Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacy Genius Jurnal Kesehatan Bakti Tunas Husada Medical Sains : Jurnal Ilmiah Kefarmasian
Yedy Purwandi Sukmawan
Bakti Tunas Husada Health Science College
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Journal : Jurnal Farmasi Indonesia

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Enoxaparin vs Fondaparinux Dalam Penurunan CK-MB yedy purwandi sukmawan; Keni Idacahyati; Rezky Fahrizal Firdaus
Jurnal Farmasi Indonesia Vol 17 No 2 (2020): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v17i2.810

Abstract

Ischemic Heart Disease (Non ST Elevated Myocardial Infarction-NSTEMI) is the leading cause of death in Indonesia after Stroke. Enoxaparin and Fondaparinux are the drugs of choice for this condition. However, there is a little study about these drugs in Indonesian people. Therefore, the objective of the study is to determine the effectivity of enoxaparin and fondaparinux in CK-MB reduction in Indonesian people. The methods of the study is retrospective observational study. A total of 43 patients were met inclusion criteria (32 in the enoxaparin group and 11 in the fondaparinux group). The outcome of the study was CK-MB reduction and the time of dyspnea was disappeared. The results of the study showed no statistic difference between enoxaparin and fondaparinux in reducing CK-MB blood plasma level (-29.00 vs -33.09; p 0.715), and also the time of dyspnea was disappeared (3.44 vs 3.09 days; p 0.347). Therefore, the choice of these agents are based on clinical condition, adverse effects and pharmacoeconomic aspects.
Co-Authors Afifah, Fitri Nur Agustin, Desi Alifiar, Ilham Anisa, Anis Billah, Tazkia Hasna Bilqis, Juwita Amanda Citra Dewi Salasanti Dianingsih, Meisye Utami Esti Deviana Esti Deviana Fauziah, Risa Nur Febrianti, Wulan Hendy Suhendy Hendy Suhendy Hendy Suhendy Hendy Suhendy Hidayati, Nurlaili Dwi Husadiani, Humaira Nursyifa I Ketut Adnyana Ilham Alifiar, Ilham Ira Rahmiyani Irma Amalia Isma, Naylatul Ismi, Sheptia Nur Jahara, Syabila Arnika Keni Idacahyati Kusmiati, Karin Kusnandar Anggadiredja Lia Amalia Maharani, Ira Maria Ulfa Maritsa Nurfatwa Meisya, Mesiya Mubarok, Samsul Muharam Priatna Nidi Halipah Nur Aulia, Iva Fadia Nur Laili Dwi Hidayati Nur Rahayuningsih, Nur Nurjahan, Nurjahan Nurjanah, Tamia Febriani Pandu Nurdiansyah Pebrianti, Setiani Putri, Nadhira Alika Putri, Suci Gandara Putri, Vicky Febriani Rahmawati Rahmawati Rani Rahmawati Ratih Aryani Rezky Fahrizal Firdaus Rojak, Rizki Ahmad Romadin, Mohammad Angga Ibnu Sarah Sahila Sidik, Hasbi Muhammad Solihah, Silfi Isyahul Sonia, Irma Sutiawan, Agus Tita Nofianti, Tita Ulfah, Nabila Maulidia Yusuf, Fitra Arif Maulana