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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Bengawan :Jurnal Pengabdian Masyarakat Scientific Journal of Dermatology and Venereology (MJN) Medical Sains : Jurnal Ilmiah Kefarmasian
Yunita Dian Permata Sari
Politeknik Indonusa Surakarta
Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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FORMULATION OF PEEL-OFF GEL MASK OF COCOA SKIN EXTRACT (Theobroma cacao L) WITH VARIED CONCENTRATION GELLING AGENT Yunita Dian Permata Sari; Diyan Sakti Purwanto; Umi Nafisah
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.1006

Abstract

Cocoa shells are waste from the plantation industry, with a fairly good potential source of energy and protein. The ethanol extract of cocoa shells contains alkaloids, flavonoids, phenols, and tannins. Cocoa shell extract has strong antioxidant activity with an IC50 value of 17.21 ppm and has sunscreen activity. This study aimed to determine the formulation and physical test of a peel-off gel mask with cocoa shell extract (Theobroma cacao L) and to determine its effect. The research method used was an experimental method with variations in the concentration of a combination of HPMC and PVA of 2%:10%, 3%:9%, 4%:8%, 5%:7%, and 0%:12%. The physical tests used on the peel-off gel mask with cocoa shell extract (Theobroma cacao L) included organoleptic, homogeneity, pH, spreadability, drying time, adhesiveness, viscosity, and cycling tests. Based on the results of the research carried out, peel-off gel mask has the characteristics of a brown color, a distinctive extract smell and a thick texture, homogeneous for F1 and F5, and not homogeneous for F2, F3, and F4, sticking force 4.53±0.24 seconds; 5.45±0.36 seconds; 8.94±0.64 seconds; 11.23±0.72 seconds; 3.87±0.70 seconds; spreadability 3.99 ± 0.18 cm; 3.33±0.31 cm; 3.47±0.78 cm; 3.32±0.50 cm; 3.05±0.42 cm; pH 6.17 ± 0.10; 6.16±0.03; 6.15±0.10; 6.11±0.05; 6.42±0.03; viscosity 19481.10±201.10; 20165.50±1.05; 20165.73±2.02; 20182.53±9.47; 14618.40±158.48. The physical stability of the gel mask preparations after treatment showed that the results of the peel-off gel mask preparations, F1 and F5, were stable. Keywords: peel-off gel mask, cocoa shell, extract, gelling agent
Antibacterial Activity of Ethanol Extract of Srikaya Leaves (Annona squamosa Linn) Against the Growth of Acne Vulgaris-Causing Bacteria Staphylococcus epidermidis Amalia, Annora Rizky; Zulaika Febru Zalsabila; Yunita Dian Permata Sari
Scientific Journal of Dermatology and Venereology Vol. 3 No. 1 (2025): Scientific Journal of Dermatology and Venereology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjdv.v2i2.143

Abstract

Introduction: Acne vulgaris, a prevalent skin condition, is primarily triggered by the proliferation of Cutibacterium acnes within pilosebaceous units. However, Staphylococcus epidermidis, a commensal skin bacterium, can exacerbate acne inflammation upon follicular invasion. This study investigates the antibacterial potential of ethanol extract derived from srikaya leaves (Annona squamosa Linn) against S. epidermidis. Methods: Srikaya leaves underwent ethanol extraction via maceration. The extract's antibacterial efficacy was assessed using the agar well diffusion method against S. epidermidis at varying concentrations (25%, 50%, 75%). Zones of inhibition were measured, and minimum inhibitory concentrations (MICs) were determined. Phytochemical screening of the extract was conducted to identify potential bioactive compounds. Results: The ethanol extract of srikaya leaves exhibited significant antibacterial activity against S. epidermidis. Increasing extract concentrations led to larger zones of inhibition, indicating a dose-dependent effect. The MIC of the extract against S. epidermidis was determined to be 50%. Phytochemical analysis revealed the presence of flavonoids, phenols, and alkaloids, which are known for their antimicrobial properties. Conclusion: Ethanol extract of srikaya leaves demonstrates promising antibacterial activity against S. epidermidis, suggesting its potential as a natural therapeutic agent for managing acne vulgaris. Further research is warranted to elucidate the mechanisms of action and evaluate the extract's efficacy in clinical settings.
Edukasi Tentang Diates Melitus Di Lingkungan Rt 07/Rw 03 Jajar, Laweyan Antari, Ester Dwi; Purwanto, Diyan Sakti; Sari, Yunita Dian Permata
Bengawan : Jurnal Pengabdian Masyarakat Vol 5 No 1 (2025): June
Publisher : Politeknik Indonusa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/jurnal_bengawan.v5i1.202

Abstract

Diabetes melitus (DM) atau diabetes merupakan penyakit kelainan metabolisme yang ditandai dengan hiperglikemia (kadar glukosa yang tinggi dalam darah) karena kekurangan insulin, resistensi insulin atau keduanya. Melalui kegiatan edukasi ini, diharapkan masyarakat RT 07/RW 03 Jajar dapat lebih memahami pentingnya menjaga kesehatan, mengenali gejala awal DM, dan menerapkan langkah-langkah pencegahan sejak dini. Pengabdian ini juga merupakan bentuk implementasi tridharma perguruan tinggi dalam mendukung program promotif dan preventif di bidang kesehatan masyarakat. Metode pelaksanaan pengabdian kepada masyarakat ini dilakukan dengan metode ceramah, tanya jawab, dan evaluasi kegiatan. Hasil pengabdian masyarakat ini Perubahan perilaku ini menunjukkan bahwa pengabdian telah berhasil membentuk kesadaran kolektif dan mengarahkan komunitas pada pola pikir preventif. Masyarakat tidak lagi bersikap pasif, melainkan mulai aktif mencari informasi kesehatan dan mendiskusikan kebiasaan hidup sehat dalam lingkungan sosial mereka. Dengan demikian, hasil pengabdian ini mampu mereduksi permasalahan awal, yaitu rendahnya pengetahuan dan kesadaran masyarakat tentang DM. Edukasi yang diberikan telah menjawab kebutuhan informasi, membentuk sikap kritis terhadap gaya hidup, dan memperkuat komitmen masyarakat untuk mencegah DM sejak dini. Hal ini menjadi bukti bahwa tujuan Pengabdian Kepada Masyarakat, yaitu meningkatkan literasi kesehatan dan memberdayakan masyarakat dalam upaya pencegahan penyakit tidak menular, telah tercapai dengan baik.
The Potential of Sugarcane Bagasse (Saccharum officinarum Linn.) as a Basic Ingredient for Making Cosmetics and Its Effectiveness as an Exfoliator and Skin Moisturizer Suhesti, Iin; Sari, Yunita Dian Permata; Oktofiani, Fauziyah; Janah, Aprillia Nurul
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 1: March 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i1.27915

Abstract

Sugarcane bagasse (Saccharum officinarum Linn.) contains most of the phenolic compounds including gallic acid, ferulic acid, epicatechin, quercetin, and kaempferol. Various phenolic compounds contained in sugarcane bagasse, especially phenolic acids, have important bioactivity for the cosmetics industry. The aim of this research is to determine the potential of sugarcane bagasse as an active ingredient in cosmetics and its effectiveness as an exfoliator and skin moisturizer. This research method is experimental, using sugarcane bagasse samples with concentrations of 1%, 3% and 5%. The results of phytochemical screening showed that sugarcane bagasse contains phenolic compounds, flavonoids and phytosterols. Based on the research results, sugarcane bagasse exfoliating gel at concentrations of 1%, 3%, and 5% increased skin tone respectively, namely 1.00 ± 0.67; 0.40±0.49; and 0.30 ± 0.39. Sugarcane bagasse moisturizing gel at concentrations of 1%, 3%, and 5% had a percent increase in skin water content, respectively, namely 6.92 ± 11.094; 2.72±10.21; and 3.36 ± 6.49. Based on SPSS analysis, it is known that variations in the concentration of bagasse extract and the time of use have a significant effect on increasing skin tone. Meanwhile, variations in the concentration of bagasse extract did not have a significant effect on increasing skin water content. However, the time of use has a significant effect on the increase in skin water content. So, it can be concluded that sugarcane bagasse extract has the potential to be an active ingredient in making cosmetics and is effective as an exfoliator and skin moisturizer.
COST OF ILLNESS STROKE TREATMENT: A SYSTEMATIC REVIEW Izzah, Raihana Nurul; Alia, Dina Fatma; Amalia, Annora Rizky; Sari, Yunita Dian Permata
Medical Journal of Nusantara Vol. 5 No. 1 (2026): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v5i1.1957

Abstract

Cardiovascular disease remains the leading cause of death worldwide, with stroke playing a significant role in increasing morbidity, mortality, and the global economic burden. This study aimed to systematically review the cost of illness and health expenditure associated with stroke across different countries. A systematic review was conducted using PubMed, ScienceDirect, and Springer databases for articles published between 2021 and 2026, following PRISMA guidelines. Studies included in the criteria were original research that reported direct and/or indirect costs due to stroke, both in primary health care facilities and in hospitals. Data extraction, screening, and quality assessment were performed using the CHEERS checklist. A total of 13 studies met the inclusion criteria. The findings showed that most studies (76%) applied the Cost Of Illness (COI) approach, while the rest used Health Expenditure (HE) methods. Direct medical costs, particularly those from inpatient care, constitute the largest component of stroke-related expenditures. Cost estimates show considerable variation between countries, with expenditures tending to be higher in high-income countries than in middle-income countries. Clinical severity, length of hospital stay, stroke subtype, and sociodemographic factors were identified as key determinants influencing total costs. Indirect cost components such as lost productivity and premature death also contribute significantly, but their reporting has not been consistent across studies. In conclusion, stroke imposes a substantial and heterogeneous economic burden influenced by methodological approaches, perspectives, and healthcare system differences. Comprehensive evaluation including both direct and indirect costs is essential to support effective health policy and resource allocation.
Co-Authors Alia, Dina Fatma Amalia, Annora Rizky Diyan Sakti Purwanto Izzah, Raihana Nurul Kiky Adhianna Sulistyawati Muhammad Dani Riano Purwanto, Diyan Sakti suhesti, iin Umi Nafisah Vania Santika Putri Yuliana Salma Eka Ningsih Zulaika Febru Zalsabila