Article Per Year (5 Year)
p-Index From 2021 - 2026
2.595
P-Index
This Author published in this journals
All Journal Jurnal Riset Kefarmasian Indonesia Lumbung Farmasi : Jurnal Ilmu Kefarmasian SEGARA : Jurnal Pengabdian Kepada Masyarakat Journal of Research in Pharmacy and Pharmaceutical Sciences Jurnal Intelek Insan Cendikia Jurnal Serina Abdimas Jurnal Abdimas Mahakam
Primayanti Nurul Ilmi
Pharmacy Program Study, Faculty Of Medicine, Universitas Pembangunan Nasional Veteran Jakarta, Jakarta Selatan, Jakarta, Indonesia
Religion Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 16 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 16 Documents
Search

 1   2 
PRESCRIPTION’S COMPLIANCE OVERVIEW IN ADMINISTRATIVE, PHARMACEUTICAL, AND CLINICAL ASPECTS AT PHARMACY DEPOT IN CLINIC X IN DEPOK CITY Putri Larasati Wibowo; Primayanti Nurul Ilmi; Erna Harfiani; Dhigna Luthfiyani Citra Pradana
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 3 No 1 (2024): Vol.3 No.1 JUNE (2024)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v3i1.8950

Abstract

Medication error is any incident that occurs during the treatment process that can jeopardize a patient's life, result in inappropriate healthcare services, and fundamentally can be prevented at various stages of treatment The National Patient Safety Map report states that medication administration errors rank first (24.8%) among the top 10 reported incidents of medication errors.Bottom of Form Top of FormBottom of Form The main duty of a pharmacist is to prevent errors in the use of medication or medication errors. Prevention includes steps such as reviewing prescriptions. The standards used are regulated by Minister of Health Regulation Number 73 of 2016, where prescription review activities include administrative review, pharmaceutical suitability, and clinical considerations. The purpose of this study is to determine the completeness of prescriptions in terms of administrative, pharmaceutical, and clinical aspects at Pharmacy X. The method used in this research is descriptive with a retrospective approach. There were 255 patient prescription data that met the study criteria. The compliance of prescriptions at Pharmacy X is still not fulfilled in terms of patient weight (0%), doctor's telephone number (0%), dosage form (16.1%), and drug strength (40%). However, the potential for drug interactions in prescriptions at Pharmacy X is quite good, with 23 out of 255 prescriptions (9%) indicating potential interactions.
NON-APPROVED INDICATION USE OF CYPROHEPTADINE AND ITS IMPLICATIONS FOR PATIENT SAFETY AND REGULATION Shabrina Adinda Septiarani; Arya Gading Purwanto; Vivi Septiani Putri; Nabilah Siti Zahara; Alisha Dian Prasasti; Karina Insanillahiya; Kannaya Sabriena Keenan Iswanto; Aisyah Humairah; Primayanti Nurul Ilmi
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 4 No 1 (2025): Vol.4 No.1 JUNE (2025)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v4i1.11251

Abstract

Cancer related anorexia and cachexia significantly impair nutritional status, quality of life, and treatment outcomes. While appetite stimulants like megestrol acetate and dronabinol have shown effectiveness, their adverse effects limit long-term use. Cyproheptadine, a first-generation antihistamine and serotonin antagonist, has emerged as a potentially safer alternative. This review aims to evaluate critically synthesize previous research findingson clinical studies, randomized trials, and retrospective analyses on cyproheptadine’s efficacy and safety as an appetite stimulant. It has shown consistent benefits across various populations, including children with cystic fibrosis, patients with nonorganic failure to thrive, and adults with cancer-related cachexia. Improvements include significant appetite score increases (e.g., K-ESAS change of –2.42 vs. –2.03 with placebo; p = 0.0307), average weight gains of ~24 g/day, and improved BMI and nutritional markers such as albumin and hemoglobin. The most common side effect was mild drowsiness, while serious adverse effects like hepatotoxicity were rare. However, concerns remain about off-label overuse in community settings, often due to lack of patient education and regulatory oversight. Overall, cyproheptadine appears to be an effective and well-tolerated short-term option for appetite stimulation. Nonetheless, more research is needed to establish long-term safety, efficacy, and appropriate dosing guidelines.
LITERATURE REVIEW: NON-INDICATED USE OF N-ACETYLCYSTEINE AGAINST OXIDATIVE STRESS-MEDIATED ORGANOPHOSPHATE TOXICITY aurelie_reginia iteh; Primayanti Nurul Ilmi; Amara Ayu Karlina; Bimo Asrul Seno; Femmita Alifa Yushanti; Haurannisa Zidny; Na’Ilah Faizah Saifani Archam; Pirda Baroqah; Tisya Mayra Arsalna Poetri; Vivian Xaviera Azzahra
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 5 No 1 (2026): Vol.5 No.1 JUNE (2026)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v5i1.11280

Abstract

Organophosphate poisoning poses a significant health threat due to its ability to induce oxidative stress, cellular damage, and neurotransmitter disruption. Pharmacovigilance plays a crucial role in monitoring and preventing adverse effects associated with medical products, including responses to toxic exposure. This study aims to evaluate the protective role of N-acetylcysteine (NAC) against organophosphate-induced toxicity through a comprehensive literature review. The method employed includes a review of eight experimental studies conducted between 2017 and 2023, involving both in vivo (animal models) and in vitro (cell cultures and human samples) approaches. The results indicate that NAC significantly reduces oxidative stress biomarkers, enhances antioxidant enzyme activity, suppresses apoptosis, and restores inhibited cholinesterase activity. Moreover, NAC improves histopathological alterations in organs exposed to organophosphates, including the liver, kidneys, brain, and testes. In conclusion, NAC demonstrates strong therapeutic potential as a standalone or adjunct agent in managing organophosphate toxicity through its antioxidant, anti-inflammatory, and cytoprotective mechanisms.
LITERATURE REVIEW: OFF LABEL USE ON , METFORMIN AS TREATMENT FOR POLYCYSTIC OVARY SYNDROME (PCOS) Shabina Putri Alliya; Anggi Isnaini; Vian Saltiel Harefa; Dafni Aisyah Fariby; Najwa Adella Feriska; Falesya Jovanka Athallah; Anisa Puja Ningrum; Daniah Atikah; Primayanti Nurul Ilmi
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 4 No 1 (2025): Vol.4 No.1 JUNE (2025)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v4i1.11286

Abstract

Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder affecting reproductive-aged women and is often accompanied by insulin resistance and hyperandrogenism. Metformin, a first-line antidiabetic agent, has been widely used in the treatment of PCOS due to its ability to improve insulin sensitivity, regulate menstrual cycles, reduce androgen levels, and promote ovulation. This literature review aims to critically evaluate and synthesize previous research findings on metformin and the influence of genetic and metabolic factors on individual responses in PCOS patients. Nine clinical studies published in the last five years were analyzed. The findings indicate that metformin consistently improves hormonal and metabolic parameters, particularly in overweight or insulin-resistant patients. Combination therapies, such as metformin with pioglitazone, liraglutide, or exenatide, were shown to be more effective than monotherapy in managing metabolic dysfunction and reproductive abnormalities. However, gastrointestinal side effects and interindividual variability in therapeutic response remain significant challenges. These results suggest that personalized treatment strategies based on patient phenotype and tolerance may optimize outcomes. Further research is needed to establish predictive markers and refine therapeutic regimens for long-term PCOS management.
THE IMPACT OF ANTI-TUBERCULOSIS DRUG ADVERSE EFFECTS ON MEDICATION COMPLIANCE IN PATIENTS WITH TUBERCULOSIS IN INDONESIA: A SYSTEMATIC LITERATURE REVIEW Annisa Hasna Nabila; Dewi Amelia; Naufal Brian Atmaja; Nadya Fierdini Putri; Tristan Setiawan; Primayanti Nurul Ilmi
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 4 No 1 (2025): Vol.4 No.1 JUNE (2025)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v4i1.12402

Abstract

Tuberculosis (TB) remains a major public health problem in Indonesia, with treatment success highly dependent on patients’ adherence to anti-tuberculosis drug regimens. However, adherence is often hindered by adverse drug reactions (ADR), including nausea, vomiting, gastrointestinal disturbances, loss of appetite, and other symptoms that discourage patients from completing therapy. This systematic literature review aimed to analyze the impact of ADR on medication adherence among TB patients in Indonesia. Literature searches were conducted in Google Scholar, PubMed, and ScienceDirect databases using predefined keywords, with inclusion criteria covering articles published between 2020 and 2025, written in English or Indonesian, full-text available, and focusing on the relationship between ADR and treatment adherence. From the 22 eligible studies reviewed, the majority reported a significant relationship between ADR and adherence, while several studies indicated no significant effect. The most frequently reported ADR were gastrointestinal disorders, headaches, joint pain, and skin reactions. In addition, psychosocial factors such as family support, knowledge, and patient attitudes were also identified as influencing adherence, with family support emerging as the most dominant factor. Overall, ADR were found to negatively affect adherence in many cases, potentially increasing the risk of multidrug-resistant TB. Strengthened patient education, proactive counseling, and closer monitoring from healthcare providers are recommended to improve adherence and treatment outcomes.
SYSTEMATIC LITERATURE REVIEW: THE PATTERN OF PSYCHOTROPIC DRUG UTILIZATION IN THE JKN ERA Anggita Cahya Ningrum; Tirta Fitri Aryani; Nadhifa Zalfa Rakhmat; Fathan Mubiin Ibnu Ismail; Putri Alifia Zahra; Primayanti Nurul Ilmi
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 4 No 2 (2025): Vol.4 No.2 DECEMBER (2025)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v4i2.12422

Abstract

Psychotropic drugs are essential in the management of mental disorders, yet their use often raises challenges related to rational prescribing, cost, and drug availability. Since the implementation of the Indonesian National Health Insurance (JKN) in 2014, changes in the utilization patterns of psychotropic medications have been observed and require systematic evaluation. This study aimed to review the prescribing patterns of psychotropic drugs in the JKN era, focusing on the most frequently used agents, therapeutic shifts, and their implications for healthcare access and financing. A systematic literature review was conducted using databases including Neliti, Garuda, ResearchGate, and Google Scholar. The search used the keywords “psychotropic,” “JKN,” “BPJS,” and “drug utilization.” Inclusion criteria were observational studies conducted in the Indonesian population between 2014 and 2025. From 124 identified publications, three articles met the inclusion criteria and were analyzed. The studies revealed a shift in the use of antipsychotics from typical to atypical agents, with risperidone as the most frequently prescribed. For antidepressants, selective serotonin reuptake inhibitors (SSRIs), particularly fluoxetine and sertraline, were commonly used, although amitriptyline remained an alternative due to limited drug availability. JKN contributed to improved patient access to treatment but was also associated with cost burden, unequal distribution of medicines, and risks of irrational prescribing. JKN has successfully expanded patient access to psychotropic therapy; however, it also introduced financial and prescribing challenges. Among mental health conditions, bipolar disorder showed a significant difference in annual costs between JKN and non-JKN patients, with higher costs under JKN mainly due to the high utilization of sodium divalproex.
Co-Authors Ade Abiyyatun Mahdiyyah Ade Abiyyatun Mahdiyyah Aisyah Humairah Alisha Dian Prasasti Amara Ayu Karlina Andiri Niza Syarifa Andiri Niza Syarifa Andiri Niza Syarifah Andiri Niza Syarifah Anggi Isnaini Anggita Cahya Ningrum Anisa Puja Ningrum Annisa Farida Muti Annisa Farida Muti Annisa Hasna Nabila Ariska Deffy Anggarany, Ariska Deffy Arya Gading Purwanto Aulia Farkhani aurelie_reginia iteh Ayu Rana Esadini Ayu Rana Esadini Bimo Asrul Seno Dafni Aisyah Fariby Daniah Atikah Delphia Hermada Marchia Dewi Amelia Eldiza Puji Rahmi Erna Harfiani Falesya Jovanka Athallah Farkhani, Aulia Fathan Mubiin Ibnu Ismail Femmita Alifa Yushanti Haurannisa Zidny Hilda Fauziah Ima Maria Imam Prabowo Imam Prabowo Kannaya Sabriena Keenan Iswanto Karina Insanillahiya Nabilah Siti Zahara Nadhifa Zalfa Rakhmat Nadya Fierdini Putri Najwa Adella Feriska Naufal Brian Atmaja Na’Ilah Faizah Saifani Archam Nurfitri Bustamam Pirda Baroqah Putri Alifia Zahra Putri Larasati Wibowo Rika Revina Sartika, Luthfiah Dewi Shabina Putri Alliya Shabrina Adinda Septiarani Silmi Syauqia Zulfa Syarifah, Andiri Niza Tirta Fitri Aryani Tisya Mayra Arsalna Poetri Tristan Setiawan Via Rifkia Via Rifkia Rifkia Vian Saltiel Harefa Vivi Septiani Putri Vivian Xaviera Azzahra Wafa Wafa