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Adia Putra Wirman
Universitas Muhammadiyah Prof DR. Hamka, DKI Jakarta, Indonesia
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ANTIOXIDANT ACTIVITY AND DETERMINATION OF TOTAL TANNIN CONTENT OF 70% ETHANOL EXTRACT OF PLETKAN LEAVES (Ruellia tuberosa L. Wirman, Adia Putra
Jurnal Kedokteran Mulawarman Vol 12, No 2 (2025): Jurnal Kedokteran Mulawarman
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v12i2.16830

Abstract

Pletekan leaves are found in many regions in Indonesia, traditionally used for the treatment of hypertension, diabetes and antioxidants. Pletekan plants contain tannin compounds with phenol groups which are known to have biological effects such as antioxidants through mechanisms as free radical traps and electron donors. The aim of the research was to determine antioxidant activity using the ABTS (2,2-azinobis 3- ethyl benzothiazoline-6-sulfonic acid) method and testing total tannin content using the spectrophotometric method and Folin-Ciocalteu reagent and tannic acid as standards. Based on the research results, the 70% ethanol extract of Pletekan leaves has antioxidant activity as a free radical reducer which is in the medium category with an IC50 value of 215.07 ± 11.65µg/ml while the total tannin content is 114.60 ± 4.1 mg TAE/g.
Co-Authors Aggasy, Savira Yustinah Alfian Anisa Amalia DIAN LESTARI Etin Diah Permanasari Euis Purbasari Faridlatul Hasanah Fatimah Nisma Fith Khaira Nursal Gantini, Sri Nevi Hadi Nasbey Hadi Sunaryo Halida Sophia Hariyanti Hariyanti Hurip Budi Riyanti Kori Yati Kristiana, Helda Ladeska, Vera Lucy Efrieni Meri Suzana Meri Suzana Nurjanah, Desi Nurul Azmah Nikmatullah Oktadio Erikardo Purbasari, Euis Rahmadini, Nuriza Rahmi Wirman Wijiastuti Wijiastuti Yeni Yeni Yunazar Manjang