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Wiwit Sulistyasmi
Poltekkes Kemenkes Bengkulu
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On The Job Training Diabetes Melitus sebagai Risiko Penyakit Jantung di Desa Sri Kuncoro: Penelitian Halimatussa’diah; Wiwit Sulistyasmi; Jon Farizal; Ari Susanto
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 4 No. 3 (2026): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 4 Nomor 3 (Januari 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v4i3.4761

Abstract

Diabetes melitus sangat meningkatkan risiko penyakit kardiovaskular termasuk penyakit jantung iskemik, stroke, dan gagal jantung. Komplikasi kardiovaskular ini berkontribusi terhadap sebagian besar morbiditas dan mortalitas terkait diabetes mellitus. Kader posyandu perlu meningkatkan pengetahuan tentang deteksi dini, pemantauan, dan pendampingan pasien DM, penyakit jantung, termasuk faktor risiko, gejala, dan langkah-langkah pencegahan yang dapat dilakukan oleh masyarakat. Tujuan dari kegiatan pengabdian masyarakat, meningkatkan pengetahuan dan kemapuan kader kesehatan melalui on the job training diabetes melitus sebagai risiko penyakit jantung di desa Srikuncoro. Identifikasi Kader mengikuti pelatihan. Pemberian materi pelatihan dan praktik cara penggunaan alat POCT dan alat tensimeter. Praktik Lapangan, pendampingan dan evaluasi program pengabdian masyarakat dilakukan secara bersamaan. Dari 30 orang Kader yang mengikuti kegiatan dipilih 10 orang yang dilatih melakukan penyuluhan, menggunakan tensimeter dan alat POCT. Kader melakukan penyuluhan dan pemeriksaan tekanan darah dan pemeriksaan darah menggunakan alat POCT, pada saat pertemuan ibu ibu PKK di Balai Desa Srikuncoro. Dari 44 orang masyarakat yang telah diperiksa darahnya, didapatkan 2 orang yang gula darah dan kolesterolnya mengalami kenaikan. Kader yang telah dilatih, mampu menggunakan alat POCT dengan baik, dan melakukan pemeriksaan tanpa didampingi. Kader mengetahui Diabetes melitus sebagai risiko penyakit jantung, meningkatnya ketrampilan kader menggunakan alat POCT dan tensimeter, melakukan edukasi, terbaginya alat POCT pada 5 kelompok kader kesehatan di Desa Srikuncoro. Disarankan untuk memberikan edukasi secara berkala mengenai penyakit Diabetes melitus sebagai risiko penyebab penyakit jantung.
Diagnostic Accuracy of ELISA Compared to Rapid Diagnostic Tests for Toxoplasmosis: A Systematic Review Fuzianingsih, Eka Noviya; Sulistyasmi, Wiwit; Kuncara, Rachmad Bayu; Sulastri, Sulastri
Academic Hospital Journal Vol 8, No 1 (2026)
Publisher : Rumah Sakit Akademik Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ahj.v8i1.112818

Abstract

Background: Toxoplasma gondii is an obligate intracellular protozoan responsible for toxoplasmosis, a globally prevalent parasitic infection affecting more than one-third of the world’s population. Accurate and timely diagnosis is crucial, particularly for pregnant women and immunocompromised individuals, to prevent severe complications such as congenital toxoplasmosis and encephalitis. The enzyme-linked immunosorbent assay (ELISA) is widely regarded as a reference serological method due to its high sensitivity and specificity. In contrast, rapid diagnostic tests (RDTs) offer practical advantages but show variable diagnostic performance.Method: This systematic review evaluated and compared the diagnostic accuracy of ELISA and RDTs for toxoplasmosis. Literature searches were conducted in PubMed and Google Scholar for studies published between 2015 and 2025. Eligible studies assessed the diagnostic performance of ELISA and RDTs for detecting T. gondii infection in human populations, including sensitivity, specificity, and overall accuracy.Result: Five studies met the inclusion criteria. Across diverse populations, ELISA consistently demonstrated high diagnostic accuracy, with sensitivity and specificity exceeding 90% in most studies. In contrast, RDTs showed lower performance and greater heterogeneity, particularly in individuals with low antibody titers and in immunocompromised individuals. Nevertheless, RDTs provided operational advantages for rapid screening in low-resource settings.Conclusion: ELISA remains the most reliable method for serological diagnosis of toxoplasmosis, while RDTs may serve as complementary tools for initial screening. The integration of both approaches, along with the adoption of advanced ELISA formats such as recombinant antigen-based or Nano-Gold ELISA, may improve early detection and enhance diagnostic capacity across different healthcare settings.
URINE KETONE LEVELS IN TUBERCULOSIS PATIENTS IN THE TELAGA DEWA COMMUNITY HEALTH CENTER AREA OF BENGKULU CITY IN 2025 Putri Rahmadani; Putri Widelia Welkriana; Wiwit Sulistyasmi
Proceeding of Banten Internasional Conference on Health Advancement and Research Vol. 1 No. 1 (2026): Proceeding Banten International Conference on Health Advancement & Research (BI
Publisher : Poltekkes Kemenkes Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Ketonuria, the presence of ketones in urine, occurs when the body breaks down fat as energy due to a lack of carbohydrates. This process produces ketone bodies (acetone, acetoacetic acid, 3-hydroxybutyric acid). This condition often occurs in people with tuberculosis (TB) due to decreased appetite and side effects of medications that cause a lack of carbohydrate intake. Tuberculosis is a global infectious disease, where Indonesia has the second highest cases in the world. In Bengkulu City, tuberculosis cases are increasing, with the Telaga Dewa Health Center recording the most cases. Tuberculosis is caused by the bacterium Mycobacterium tuberculosis which is airborne and is risky for all ages. This study aims to find out the description of urine ketone in tuberculosis patients at the Telaga Dewa Health Center, Bengkulu City in 2025. The sample in this study was 27 people using the accidental sampling method. The examination was carried out using the rothera method. The results of the distribution of urine ketone frequency in tuberculosis patients were obtained with 15% positive urine ketone and 85% negative urine ketone results. Based on the results of the research on Urinary Ketone, overview in Tuberculosis Patients at the Telaga Dewa Health Center, Bengkulu City in 2025 on 27 samples, the following results were obtained 15% were positive for urinary ketone. The results of this study are expected for the community, especially tuberculosis patients, to maintain good health and diet.
The Role of Vitamin D in TNF-α Levels in Pulmonary TB Patients Sahidan, Sahidan; Sulistyasmi, Wiwit; Farizal, Jon; Hartini, Supri; Ujiani, Sri
MEDICA (International Medical Scientific Journal) Vol. 8 No. 4 (2026): MEDICA (International Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v8i4.908

Abstract

Tuberculosis (TB) remains a major global health problem, with immune responses particularly tumor necrosis factor-alpha (TNF-α) playing a key role in disease progression. Vitamin D, synthesized through sunlight exposure, has been suggested to modulate immune responses; however, its effect on TNF-α in TB patients remains unclear. This study aimed to evaluate the effect of sunlight exposure on TNF-α levels in patients with pulmonary tuberculosis. A quasi-experimental pre–post study was conducted among 60 TB patients divided into control and intervention groups. TNF-α levels were measured before and after intervention and analyzed using appropriate statistical tests, including the Wilcoxon signed-rank test. The results showed a slight increase in mean TNF-α levels after sunlight exposure; however, the difference was not statistically significant (p = 0.475). Increased variability in TNF-α levels after the intervention suggests heterogeneous individual responses. These findings indicate that sunlight exposure may have a limited effect on TNF-α modulation in TB patients. Further studies with larger sample sizes and comprehensive biomarker assessments are needed to clarify the relationship between sunlight exposure, vitamin D, and immune responses in tuberculosis.
Co-Authors Andriana, Kezia Anung Sugihantono ARI SUSANTO Azahra, Sresta Duri, Iin Desmiany Febriyanto, Tedy Fuzianingsih, Eka Noviya Hadipranoto, Ichsan Halimatussa’diah Jon Farizal, Jon Kasiyati, Menik Kuncara, Rachmad Bayu Nurul Qomariyah Purlinda, Devi Etivia Puspita Sari, Dela Putri Rahmadani Putri Widelia Welkriana Ririh Jatmi Wikandari Roni Afriansya Sahidan Sahidan Sahidan, Sahidan Sasangka, Parisade Galih Setyaji, Yoki Sulastri Sulastri Supri Hartini, Supri SY. Didik Widiyanto Ujiani, Sri