Claim Missing Document
Check
Articles

Found 22 Documents
Search

Formulation And Activity Tests of Anti-Acne Toner 70% Ethanol Extract Black Garlic (Allium sativum L.) Setiawan, Abdul Aziz; Megawati, Sefi; Yuniarto, Ari; Abdulloh
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.10093

Abstract

Black Garlic (BG) is a fermented product of garlic heated at 60-70ᵒC for 14 days. Black garlic has a black color and has an aroma and taste that is not too pungent like garlic. In Black Garlic S-allylcysteine helps the absorption of allicin making metabolism against bacterial infections easier. The purpose of this study was to determine the physical evaluation and antibacterial activity of 70% ethanol extract Black Garlic (EEBG) as well as the optimum concentration of Staphylococcus aureus, Staphylococcus epidermidis, and Propionibacterium acnes. The study used Single Black Garlic (Allium sativum L.) from Lumajang, East Java, fermented for 30 days at a temperature of 70°C and humidity of 90%. Single black garlic extract is formulated in 3 formulas, including formula 1 (0,5% extract), formula 2 (1% extract), formula 3 (1,5% extract), negatif control (base) and Wardah Acnederm Pure Refining Toner as a comparison. Toner were evaluated by organoleptic testing, pH, homogeneity, and antibacterial activity. The physical results of the toner preparation meet the physical quality requirements which include (organoleptic testing, pH, and homogeneity). The results of the antibacterial activity of toner preparations in formula 1 (0,5% extract), formula 2 (1% extract), formula 3 (1,5% extract), and Commercial toner for antibacterial. The conclusion of this study shows that EEBG has promising antibacterial effects and the evaluation of all instant granules has met the specified requirements.
Ethanolic Extract of Fingerroot (Boesenbergia pandurata Roxb.) Rhizomes exhibits Analgesic and Anti-Inflammatory Activities in Swiss Webster Mice Yuniarto, Ari; Setiawan, Abdul Aziz; Asyila, Nadia Dinda
Indonesian Journal of Pharmaceutical Science and Technology Vol 13, No 1 (2026)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v13i1.66595

Abstract

Pain is a sensory response that indicates tissue damage caused by mechanical, chemical, or physical stimuli. This study aimed to evaluate the analgesic and anti-inflammatory activities of the ethanol extract of fingerroot rhizomes (EEFR) in mice. The extract was prepared by maceration using ethanol and tested in mice divided into five groups: three treatment groups receiving EEFR at doses of 100, 200, and 400 mg/kgBW, a positive control group, and a negative control group. Analgesic activity was assessed by the number of writhing responses induced by 1% acetic acid, while anti-inflammatory activity was evaluated based on paw edema induced by 1% carrageenan. The results showed that EEFR at a dose of 400 mg/kgBW produced the most significant analgesic and anti-inflammatory effects, with pain protection and inflammation inhibition percentages of 69.81% and 58.97%, respectively. These findings indicate that EEFR has potential as a natural analgesic and anti-inflammatory agent.