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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Poltekita : Jurnal Ilmu Kesehatan Jurnal Kesehatan Tambusai JOURNAL LA MEDIHEALTICO Jurnal Locus Penelitian dan Pengabdian Buletin Kedokteran dan Kesehatan Prima International Journal of Health and Pharmaceutical (IJHP) Eduvest - Journal of Universal Studies Journal of Public Health and Pharmacy
Angie, Evelyn
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Health Professions Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

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The role of family planning field extension workers (PFEW) in fertile age couples in choosing long-term contraception methods at Sekerak District Health Center Halim, Yeni; Saputri, Novia; Yuliana, Yuliana; Lubis, Ika Syani Putri; Suwarno, Suwarno; Sulistijanto, Eddy; Alexander, Rico; Fresia, Ana; Henny, Henny; Putri, Eka; Angie, Evelyn
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7451

Abstract

The lack of socialization carried out by Family Planning Field Extension Workers (FPFE) leads to fear among the community, especially among Couples of Reproductive Age (CRA), in choosing Long-Term Contraception Methods (LTCM). Couples of reproductive age require health education or counseling to help them determine which contraceptive method to use. This study aims to determine the role of PLKB for couples of reproductive age (PUS) in choosing LTCM at Sekerak District Health Center, Aceh Tamiang Regency in 2022. This study is a quantitative research with a cross-sectional design. The population in this study was all couples of reproductive age in Sekerak Kanan Village, Sekerak District, Aceh Tamiang Regency, and the research sample consisted of 126 people. Data collection was done directly by distributing questionnaires to couples of reproductive age. Then, it was followed by the process of data analysis using the Chi-Square test and logistic regression. The results showed that there is a relationship between counseling quality in choosing LTCM with a value of (p=0.001; PR=3.4; 95% CI 2.201-5.294), there is a relationship between PLKB barriers in choosing LTCM with a value of (p=0.001; PR=2.2; 95% CI 1.724-3.007), and there is a relationship between FPFE capacity in choosing long-term contraceptive methods with a value of (p=0.001; PR=2.4; 95% CI 1.704-3.472). Furthermore, the dominant factor related to the selection of LTCM is counseling quality with a value of (p=0.000; PR=10.766 95% CI 3.491-33.204). Couples of reproductive age are expected to increase their knowledge, especially about long-term contraceptive methods, and it is hoped that men will not be ashamed to participate in family planning programs.
Effectiveness of Mango Mistletoe on Lung Superoxide Dismutase in Hypertensive Rats Exposed to DOCA-Salt Darma, Surya; Angie, Evelyn; Lubis, Yuliani Mardiati; Muharraran, Firdha
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 4 (2024): February
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i4.3676

Abstract

Vascular disease, caused by oxidative stress and endothelial cell inflammation during hypertension's development, produces substantial mortality and morbidity. Mango mistletoe was tested for its effect on pulmonary superoxide dismutase (SOD) in hypertensive rats exposed to DOCA-salt in a preventative model. This study involves experimental quantitative research. SPSS was used for one-way ANOVA and post-hoc LSD testing. The population used was male Wistar rats (Rattus norvegicus). The samples used were 25 male Wistar rats divided into five treatment groups because of the Shapiro-Wilk test for normality analysis. The treatment group included a negative control group, a positive control group, and a group given different doses of mango mistletoe methanol extract: P1 at 75 mg/kgBW, P2 and P3 at 150 mg/kgBW, and P3 at 250 mg/kgBW. The study indicated that 250 mg/kg BW mango mistletoe extract increased SOD levels in DOCA-Garam-exposed Wistar white rats (Rattus norvegicus). Enhanced superoxide dismutase, malondialdehyde (MDA), ureum, creatinine, and renal histology see this. The normality of study data in the complete group assessing SOD, MDA, ureum, and creatinine levels showed a significance value larger than 0.05. The significance probability and one-way ANOVA test values are more than 0.05. The study found that mango mistletoe extract contains saponins, tannins, flavonoids, and triterpenoids that increase SOD levels and repair kidney cells damaged by hypertension in Wistar white rats. The study examined how mango mistletoe extract affects mouse hypertension. However, its conclusions should not be applied to humans. Clinical trials are needed to determine mango mistletoe extract's safety and efficacy for humans.
GAMBARAN FUNGSI HATI PADA PASIEN DIABETES MELITUS TIPE 2 DI RSU ROYAL PRIMA MEDAN TAHUN 2022 Ginting, Dicky Owenta; Angie, Evelyn; Natali, Oliviti
Jurnal Kesehatan Tambusai Vol. 5 No. 1 (2024): MARET 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i1.23543

Abstract

Diabetes Melitus merupakan penyakit dengan tingginya kadar glukosa darah, yang merupakan sumber energi utama untuk sel tubuh. Seringkali seseorang tidak menyadari apabila orang tersebut terkena diabetes, dan terlambat dalam menanganinya sehingga terjadi komplikasi. Glukosa yang menumpuk dalam darah dapat mencetuskan berbagai gangguan pada organ tubuh. Pada pasien Diabetes Melitus (DM) tipe II terjadi peningkatan enzim hati (AST/SGOT dan ALT/SGPT) yang disebabkan karena adanya kerusakan dinding sel hati. Nilai AST dan ALT dapat digunakan untuk membantu melihat kondisi kerusakan fungsi sel hati. Tujuan penelitian ini adalah untuk mengetahui gambaran fungsi hati pada pasien Diabetes Melitus (DM)  tipe II di Rumah Sakit Umum Royal Prima medan tahun 2022. Penelitian ini menggunakan desain deskriptif observasional dengan menggunakan instrument penelitian data rekam medis pasien Diabetes Melitus (DM)  tipe 2 Tahun 2022. Pengambilan sampel yang digunakan dalam penelitian ini menggunakan teknik purposive sampling dengan jumlah sampel sebanyak 29 orang. Kemudian dilakukan analisis data menggunakan analisis univariat dengan perhitungan proporsi karakteristik berdasarkan variabel dengan menggunakan SPSS. Hasil penelitian menyatakan bahwa dari total 29 pasien terdapat 13 orang (44,83%) memiliki derajat SGPT ringan, 6 orang (20,69%) memiliki derajat SGOT ringan, dan 1 orang (3,45%) memiliki derajat SGOT sedang. Kesimpulan dari penelitian ini adalah pada pasien Diabetes Melitus (DM)  tipe II terdapat kenaikan kadar SGOT dan SGPT.
Linking MDA Levels and Blood Glucose in Streptozotocin-Induced Rat Diabetes: Implications for Diabetic Complications and Therapeutic Strategies Angie, Evelyn; Girsang, Ermi; Ikhtiari, Refi
Jurnal Penelitian Pendidikan IPA Vol 10 No 6 (2024): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i6.7220

Abstract

Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels resulting from insulin deficiency or resistance. Streptozotocin, a potent diabetogenic agent, is commonly employed to induce experimental diabetes by selectively damaging pancreatic beta cells, resulting in insulin deficiency and hyperglycemia. Elevated Malondialdehyde (MDA) levels, indicative of oxidative stress and lipid peroxidation, are closely linked to diabetic complications. This study aimed to investigate the association between MDA levels and blood glucose in Streptozotocin-induced rat diabetes, shedding light on potential therapeutic strategies. Spectrophotometric analysis was utilized to quantify MDA levels in rat tissues, providing insights into the extent of oxidative damage. The results revealed a significant correlation between MDA levels and blood glucose, highlighting the role of oxidative stress in diabetic pathogenesis. These findings underscore the importance of targeting oxidative stress in diabetes management to prevent complications. In conclusion, the study emphasizes the relevance of monitoring MDA levels as a biomarker for assessing oxidative stress in diabetic conditions and guiding therapeutic interventions.
Co-Authors Alexander, Rico Altamira, Vita Amir, Widya Pasca Amra, Aryani Atiyatul Apriani, Silvi Brahmana, Lisa Charolin Br Eka Putri Fitriani, Dini Dwi Fransisca, Silvia Fresia, Ana Gilbert Lister Ginting, Dicky Owenta Girsang, Ermi Halim, Yeni Hanjaya, Hanjaya Henny Henny, Henny IKHTIARI, REFI Janice Janice Jesika, Jesika Kunardi, Sidharta Leslie, William Lister, Gilbert Lubis, Ika Syani Putri Lubis, Yuliani Mardiati Muharraran, Firdha Nardi, Leo Nasution, Syamsul Arifin Natali, Oliviti Saputri, Novia Sari, Masitha Dewi Sulistijanto, Eddy Surya Darma Suwarno Suwarno Yani, Herlina Yuliana Yuliana