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All Journal TAZKIYA JOURNAL OF PSYCHOLOGY Jurnal Kesehatan Andalas Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Anatomica (Anatomica Medical Journal) JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education World Nutrition Journal Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Madani : Jurnal Pengabdian Kepada Masyarakat Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Journal of Religion and Public Health
Pasiak, Taufiq Fredrik
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Religion Humanities Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Experts’ Opinion on Immunity and Nutrition to Support Key Cognitive Functions Sekartini, Rini; Surapsari, Juwalita; Oktarina, Molly Dumakuri; Wiguna, Tjhin; Pasiak, Taufiq Fredrik; Basrowi, Ray Wagiu; Kartjito, Melissa Stephanie; Wasito, Erika
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0001

Abstract

The interaction of micronutrients and macronutrients has been shown to have a significant impact on children's cognitive development. Furthermore, proper nutrition helps a child's immune system avoid infection and disease, which can impair nutrient absorption and lead to deficiency. Microbiotas in the gut play critical roles in body physiology, including nutrient absorption, infection resistance and immune system development. Furthermore, it is known that the gut microbiota influences immune cell maturation. Finally, these three factors are thought to influence neurogenesis and cognitive development. A virtual meeting was held with five invited experts to gain a better understanding of the relationship between nutritional factors, the immune system and cognitive development.
The narrative review of recent studies in understanding the relationship between gut (microbiota)-brain axis, nutrition and cognitive function Pasiak, Taufiq Fredrik; Wiguna, Tjhin; Sekartini, Rini; Surapsari, Juwalita; Sundjaya, Tonny; Wasito, Erika; Basrowi, Ray Wagiu; Kartjito, Melissa Stephanie
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0004

Abstract

The concept of the gut (microbiota)-brain axis, which influences the development and function of the gastrointestinal, immune, neuroendocrine, and metabolic systems, is gaining popularity. Recent animal studies have demonstrated that the gut (microbiota)-brain axis also plays a role in establishing cognitive function. It is known that a disruption in the environment's microbiota balance can increase disease susceptibility in children. Historically, it has been hypothesized that neurodevelopmental disorders are the results of a disruption in children’s health. However, it is becoming clear that the gut microbiota and the central nervous system communicate in both directions, which could explain how microbiota affects cognitive function. Dietary factors also play important role in the central nervous system via the gut (microbiota)-brain axis, demonstrating the importance of nutrition in optimizing cognitive function. This narrative review of recently published studies and current knowledge aims to elucidate the relationship between the gut (microbiota)-brain axis and cognitive function, as well as the variables that may influence it.
Exploring key cognitive indicators for practical use by parents in community setting Wiguna, Tjhin; Sekartini, Rini; Pasiak, Taufiq Fredrik; Basrowi, Ray Wagiu; Kartjito, Melissa Stephanie
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0005

Abstract

The identification of child development milestones, specifically cognitive abilities, requires parental/caregiver awareness and knowledge. With the existence of multiple cognitive abilities such as attention and focus, memory, language, psychomotor skills, logic, reasoning, decision-making, problem-solving, social/emotional, there are multiple indicators to measure children's cognitive abilities. Pediatricians are the most knowledgeable and trusted authority to routinely screen and monitor the development of healthy children. Therefore, it is crucial that parents understand their children's developmental milestones so if they encounter anomalies, they can immediately consult with the professionals. This review compiles recently published research and current knowledge to examine potential key indicators of cognitive development in infants and children that can be utilized by parents and communities in an easily understood manner.
A Neuroscience Approach to a Virtual Reality (VR) Based Accommodation–Convergence Intervention for Evaluating Intra-Individual Mental Fatigue during Nearwork: A Crossover Experimental Study Concept Hartono, Riyadi; Pasiak, Taufiq Fredrik; Thadeus, Maria Selvester
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 9 No. - (2025): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v9i-.320

Abstract

Introduction: Prolonged nearwork is associated with increased mental fatigue, a neurocognitive state marked by slower processing, reduced accuracy, and diminished executive performance. This condition affects up to 60–70% of students and office workers worldwide. Objective: Analyzing the effect of a VR-based Accommodation–Convergence Intervention on intra-individual mental fatigue parameters during nearwork from a neuroscience perspective. Methods: A crossover experimental study was developed involving 20 healthy male participants (18–25 years) to perform identical 60-minute Pauli test under two conditions: (1) 2D screen-based and (2) 3D VR based (reduce accommodation–convergence by projecting visual object at optical infinity). Mental fatigue was assessed using several biomarkers, including Pauli test performance, P300 amplitude and latency, and EEG Alpha–Theta PSD. Intra-individual differences between conditions were analyzed using a within-subject. The conceptual framework  was supported by a synthesis of 100 peer-reviewed studies (2014–2024) establishing mental fatigue indicators biomarker. Results: Hypothetically, comparisons between 2D screen and 3D VR-based demonstrated improvement in endurance, reflected by a higher Pauli test performance slope, attenuating the increase in P300 latency-amplitude as well as changes in EEG Alpha–Theta indicative of mental fatigue. The results showed a trend of VR exposure across multiple biomarkers, although the confidence intervals were wide in this small-sample pilot study. Conclusion: This study illustrated a neuroscience-based framework demonstrating that accommodation–convergence intervention via VR may influence indicators of mental fatigue. By integrating EEG, P300, and the Pauli test, the approach provides an objective model for assessing intra-individual cognitive endurance.
Co-Authors Aisyah, Ammara Amzi, Djakiyah Kalsum Basrowi, Ray Wagiu Chintia Chintia, Chintia Cut Fauziah Digna, Audrey Alvura Dwi Arwandi Yogi Saputra Erna Harfiani Hapit, Rizki Pauziah Hartono, Riyadi Idhsa, Yasmin Azizah Imam Prabowo, Imam Isvandiary, Astea Adzani Kartjito, Melissa Stephanie Listianto, Herdan Makkiyah, Feda Anisah Maria Selvester Thadeus Masiran, Ruziana` Meiskha Bahar Mulyani, Anisa Sri Natanel, Handro Steve Nugraha, Yudhi Oktarina, Molly Dumakuri Pritha Maya Savitri Rahmah Hida Nurrizka Rahmah, Muthia Reiza, Muhammad Retno Yulianti Ria Maria Theresa Rini Sekartini Sundjaya, Tonny Surapsari, Juwalita Tjhin Wiguna Uswatun Hasanah Wasito, Erika Yanti Harjono Hadiwiardjo