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All Journal BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Indonesian Journal of Community Empowerment and Service Molekul: Jurnal Ilmiah Kimia Rafflesia Journal of Natural and Applied Sciences (RJNAS) Jurnal Biosilampari: Jurnal Biologi
Khafit Wiradimafan
Jurusan Kimia, FMIPA Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Kombinasi Ekstrak Metanol Daun Ketepeng Cina (Cassia alata Linn.) dengan Enam Ekstrak Tumbuhan Terpilih dalam Menghambat Pertumbuhan Bakteri Staphylococcus aureus Lisna Hamni; Avidlyandi Avidlyandi; Charles Banon; Khafit Wiradimafan; Deni Agus Triawan; Risky Hadi Wibowo; Morina Adfa
BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains Vol 5 No 2 (2022): BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/bioedusains.v5i2.3996

Abstract

This study aimed to determine the antibacterial activity and the effect of the combination of methanol extract of the leaves of Chinese ketepeng (Cassia alata Linn.) with six selected plant extracts against Staphylococcus aureus bacteria. The method used is well diffusion and paper tape method. The concentration of the test extract was 100 mg/mL (1:1), DMSO 50% v/v was used as a negative control and the antibiotic clindamycin as a positive control. The results showed that most of the combinations of the methanol extract of the Chinese ketepeng leaf (C. alata) with the six selected plant extracts produced an average diameter of the inhibition zone, which was greater than the average diameter of the inhibition zone of every single extract. However, the average diameter of the combined inhibition zones was not more significant than the sum of the average diameters of the inhibition zones of every single extract. In conclusion, the combination of the methanol extract of the Chinese ketepeng leaf (C. alata) with six selected plant extracts had additive/indifferent effects in inhibiting the growth of S. aureus. Keywords: Antibacterial, Cassia alata Linn, Combination, Staphylococcus aureus
PENDAMPINGAN PRAKTIKUM KIMIA KELAS IPA XI DI MADRASAH ALIYAH AL-KARIM BENGKULU TENGAH Avidlyandi Avidlyandi; Adfa Morina; Wiradimafan Khafit; Yudha S Yudha S; Triawan Deni Agus; Wibowo Risky Hadi; Erliana Dina; Sari Munifilia Eka; Endarwati Wiwik Endarwati; Azizah Khusnul; Shari Winda
Indonesian Journal of Community Empowerment and Service (ICOMES) Vol. 4 No. 1: June 2024
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/icomes.v4i1.34461

Abstract

Praktikum adalah salah satu metode pembelajaran yang dapat meningkatkan minat dan pemahaman siswa terhadap konsep dan teori suatu pelajaran terutama pada mata pelajaran sains seperti kimia. Kegiatan pengabdian kepada masyarakt (PKM) ini bertujuan untuk memberikan pendampingan praktikum kimia sederhana kepada siswa kelas XI IPA di Madrasah Aliyah Al-Karim Bengkulu Tengah. Pendampingan praktikum dilakukan dengan beberapa metode yaitu metode ceramah, project base learning (PBL), diskusi dan evaluasi pemahaman siswa terhadap objek praktikum secara kuantitatif melalui pre-test dan post-test. Berdasarkan hasil observasi dan evaluasi secara langsung, pendampingan praktikum oleh tim pengabdian telah meningkatkan minat dan pemahaman siswa terhadap objek praktikum. Serta melalui kegiatan pengabdian kepada masyarakat ini juga telah mampu mengoptimalkan fungsi laboratorium dengan mengusung prinsip Green Chemistry dengan memanfaatkan bahan-bahan dari sekitar/lingkungan untuk beberapa objek praktikum.
Application of FTIR Spectroscopy and Chemometric to Differentiate Azadirachta excelsa (Jack.) Jacobs Leaves Extracts Based on Solvent Polarity and Assessment of Antibacterial Activity Adfa, Morina; Erliana, Dina; Wiradimafan, Khafit; Triawan, Deni Agus; Yudha S., Salprima; Avidlyandi, Avidlyandi; Rafi, Mohamad
Molekul Vol 19 No 2 (2024)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2024.19.2.10790

Abstract

ABSTRACT. Azadirachta excelsa is a plant belonging to the same genus as the Indian neem (Azadirachta indica) which is expected to have similar biological activities. However, its active components and pharmacological effects are limited. The composition and quantity of these metabolites in A. excelsa may differ due to different polarities of extracting solvents, so selecting an effective extractive solvent with a high level of biological activity is important. Therefore, in this study, we examined differences in the metabolite finger printing using FTIR-based metabolomics, as well as evaluated their antibacterial activity against Staphylococcus aureus (ATCC 6538) and Escherichia coli (ATCC 8739). A. excelsa was extracted using chloroform, ethyl acetate, ethanol p.a., 70% and 50% ethanol. Extracts obtained were analyzed using FTIR and the inhibition zones were then determined. The results showed that principal component analysis (PCA) could distinguish each sample based on the extraction solvent. In this study, we found 50% and 70% ethanol extracts had similar metabolite compositions and concentrations based on their respective FTIR spectrum. The inhibition zone of A. excelsa extracts ranged from 12.37-17.20 mm and 13.88-15.89 mm against S. aureus and E.coli, respectively. The chloroform extract was more effective against both bacteria. Duncan's further test showed that chloroform extract reduced E. coli similarly to ethyl acetate but not S. aureus. While 50%, 70%, and ethanol p.a. extracts inhibited S. aureus and E. coli equally. Based on these results, the polarity of the extracting solvent had an important influence on the metabolite profile and antibacterial activity of A. excelsa. Keywords: Azadirachta excelsa, antibacterial activity, metabolite fingerprinting, FTIR.
Aktivitas Antibakteri Ekstrak Etanol Daun Sungkai (Peronema canescens Jack) Terhadap 2 Jenis Bakteri Penyebab Jerawat dengan KLT-Bioautografi Erliana, Dina; Nurhasana, Devi; Wiradimafan, Khafit; Avidlyandi, Avidlyandi; Yudha, Salprima; Adfa, Morina
BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains Vol 7 No 2 (2024): Bioedusains: Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/bioedusains.v7i2.10373

Abstract

This research aims to examine the antibacterial activity of an ethanol extract of old sungkai leaves (DST) (Peronema canescens Jack) against the test bacteria Staphylococcus aureus and Staphylococcus epidermidis using the TLC-bioautography method. The concentration of the test extract was 15%, with the amount of extract spotting being 25 μL, and the eluent used was chloroform p.a. The results showed that the TLC chromatogram of DST ethanol extract showed 10 dense spots/spots, 6 spots of which could inhibit the growth of S. aureus (spots no. 2-7), and 7 of them (spots no. 1-7) could inhibit the growth of S. epidermidis. Spots with Rf = 0.06; 0.12; 0.27; 0.35 (spots no. 2-5) showed a larger clear zone than spots with Rf = 0.47 and 0.64 (spots no. 6-7) in inhibiting S. aureus. Meanwhile, spot number 1 (Rf = 0) showed the clearest zone among the other 6 spots in inhibiting S. epidermidis. In conclusion, the ethanol extract of old sungkai leaves (DST) has strong antibacterial properties against S. aureus and S. epidermidis. The results of this research have the potential to be developed to obtain potential candidate compounds as antibacterials from sungkai leaves. Keywords: Antibacterial, TLC-bioautography, Peronema canescens Jack, Staphylococcus aureus, Staphylococcus epidermidis
Pelatihan Pembuatan Minuman Kesehatan Siap Seduh di Desa Taba Air Pauh Kecamatan Tebat Karai Kabupaten Kepahiang Wiradimafan, Khafit; Adfa, Morina; Martono H.P, Agus; Andini, Vicka; Avidlyandi, Avidlyandi
Indonesian Journal of Community Empowerment and Service (ICOMES) Vol. 4 No. 2 (2024): December 2024
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/icomes.v4i2.37587

Abstract

Pelatihan pembuatan minuman jahe instan telah dilakukan di Desa Taba Air Pauh, Kecamatan Tebat Karai, Kabupaten Kepahiang, Provinsi Bengkulu. Kegiatan ini bertujuan untuk meningkatkan pengetahuan dan keterampilan masyarakat terkait pengolahan jahe, serta mempromosikan kewirausahaan berbasis industri rumahan. Jahe, sebagai komoditas lokal yang melimpah, memiliki potensi untuk dikembangkan menjadi produk minuman instan dengan nilai ekonomi yang lebih tinggi. Melalui metode ceramah dan praktek langsung, peserta diberikan pelatihan tentang cara mengolah jahe menjadi minuman sehat siap seduh. Hasil kegiatan ini menunjukkan bahwa masyarakat telah memahami proses pembuatan minuman jahe instan dan manfaatnya. Diharapkan kegiatan ini dapat membantu meningkatkan perekonomian masyarakat Desa Taba Air Pauh dengan memanfaatkan potensi lokal.
Telaah Pustaka Penggunaan Zat Aditif Sintetik dan Ekstrak Tumbuhan pada Pelapisan Tembaga secara Listrik elwarni, Fayza maya; Alvin Reagen, Muhamad; Wiradimafan, Khafit; Prima Yudha, Sal
RAFFLESIA JOURNAL OF NATURAL AND APPLIED SCIENCES Vol. 4 No. 2 (2024): Oktober
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/rjna.v4i2.39404

Abstract

Elektroplating tembaga adalah proses pelapisan logam dengan tembaga menggunakan arus listrik. Untuk mendapatkan lapisan tembaga berkualitas optimal dengan penambahan zat aditif baik sintetik maupun alami, sangat penting untuk mengontrol pertumbuhan kristal dan distribusi ion tembaga, sehingga menghasilkan lapisan tembaga dengan kilau yang tinggi, daya lekat yang kuat, dan ketahanan korosi yang baik. Penambahan PEG, DPS, SPS, IBDGE, PBDGE, Polyquaternium-2, HEDP dan berbagai ekstrak tumbuhan (kulit bakau, daun jambu biji, daun binahong, kulit buah kakao) serta gelatin dapat secara signifikan mempengaruhi morfologi, ketebalan, dan sifat khusus pada lapisan tembaga. Mekanisme kerja aditif melibatkan interaksi kompleks antara aditif, ionlogam, dan permukaan substrat.
Efektivitas penambahan aditif sintetik dan aditif alami pada elektrodeposisi nikel : sebuah telaah pustaka Afif, Muhammad adli; reagen, Muhamad alvin; wiradimafan, Khafid; Adfa, Morina
RAFFLESIA JOURNAL OF NATURAL AND APPLIED SCIENCES Vol. 4 No. 2 (2024): Oktober
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/rjna.v4i2.39408

Abstract

Penelitian ini bertujuan untuk mengetahui perbandingan dari pengaruh penambahan aditif sintetik dan alami pada elektrodeposisi nikel, Proses elektrodeposisi nikel merupakan reaksi elektrokimia yang melibatkan elektron yang disuplai oleh sumber arus searah. Reaksi terjadi pada permukaan elektroda. Ion-ion nikel dalam larutan akan tereduksi membentuk lapisan logam nikel di katoda, sedangkan di anoda akan terjadi reaksi oksidasi. Pengaruh aditif sebagai agen pereduksi selain memberikan pengaruh pada mikrostruktur deposit dapat meningkatkan jumlah arus sehingga dapat mempercepat terbentuknya deposit dan memberikan lapisan yang lebih tebal dan kilau. salah satu aditif sintetik adalah natrium lauril sulfat/sodium lauril sulfat, saccharin, Cetiltrimetilamonium Bromida, coumarin dan beberapa aditif alami antara lain Ektrak daun semanggi, Ekstrak daun Ketapang, ekstrak batang bakau, ekstrak buah kakao, dan brightener alami Daphne gnidium L.
Uji Antirayap ekstrak metanol daun ruku-ruku (Ocimum tenuiflorum) terhadap rayap tanah Coptotermes curvignathus Khairani, Nurliza; Avidlyandi, Avidlyandi; wiradimafan, khafit; Juliari Kusnanda, Arif; gustian, Irfan; adfa, Morina
RAFFLESIA JOURNAL OF NATURAL AND APPLIED SCIENCES Vol. 4 No. 2 (2024): Oktober
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/rjna.v4i2.39453

Abstract

Penelitian ini bertujuan untuk menentukan aktivitas anti termitisida ekstrak metanol daun ruku-ruku (Ocimum tenuiflorum) terhadap rayap Coptotermes curvignathus Holmgren menggunakan metode no- choice test dan penentuan komponen kimia menggunakan GC-MS. Hasil uji aktivitas termitisida diperoleh persentase tase kematian rayap meningkat seiring dengan naiknya konsentrasi yang diberikan, konsentrasi 20% menyebabkan kematian rayap mencapai 100% pada hari ke-7. Hasil GC-MS menunjukkan terdapat 70 komponen kimia pada ekstrak metanol daun ruku-ruku dimana terdapat 3 senyawa utama, 53 senyawa minor serta 14 senyawa yang belum terdeteksi, dengan senyawa utamanya adalah methyl palmitate, methyl linolenate dan 14-methyl pentadecanoic acid methyl ester.
Potential of Liquid Smoke in Inhibiting the Growth of Pathogenic Bacteria: A Mini Review Khusnul Azizah; Winda Shari; Charles Banon; Avidlyandi Avidlyandi; Khafit Wiradimafan; Salprima Yudha S.; Morina Adfa
Jurnal Biosilampari : Jurnal Biologi Vol 7 No 2 (2025): Biosilampari: Jurnal Biologi
Publisher : Universitas PGRI Silampari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62112/biosilampari.v7i2.162

Abstract

The objective of this study was to perform a comprehensive evaluation of the application of liquid smoke as a possible antibacterial agent. The studies were identified by conducting searches on multiple electronic databases, specifically Semantic Scholar, PubMed, and Google Scholar, from 2013 to 2024. The keywords used included ‘antibacterial of wood vinegar, antibacterial of pyroligneous extract, antibacterial of pyroligneous acid, antibacterial of wood distillate, antibacterial activity of liquid smoke, and aktivitas antibakteri asap cair (in Bahasa Indonesia)’. The results indicate that liquid smoke has the capacity to serve as a natural antibacterial agent against both Gram positive and Gram-negative microorganisms. The variation in antibacterial susceptibility may arise from the composition of chemical compounds present in liquid smoke, the raw materials employed in its production, the temperature of pyrolysis, and the specific testing methodology employed. This review will be useful to the industrial and scientific communities in the food science, pharmaceutical, and technology fields.
Co-Authors Afif, Muhammad adli Alvin Reagen, Muhamad Andini, Vicka Avidlyandi, Avidlyandi Azizah Khusnul Charles Banon elwarni, Fayza maya Endarwati Wiwik Endarwati Irfan Gustian Juliari Kusnanda, Arif Khairani, Nurliza Khusnul Azizah Lisna Hamni M. Rafi Martono H.P, Agus Morina Adfa Munifilia Ekasari Nurhasana, Devi Prima Yudha, Sal Reagen, Muhamad Alvin Risky Hadi Wibowo SALPRIMA YUDHA S Salprima Yudha S. Shari Winda Triawan Deni Agus Triawan, Deni Agus Wibowo Risky Hadi Winda Shari Yudha S Yudha S