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PENGARUH PENAMBAHAN EKSTRAK DAUN MANGGA MANALAGI TERHADAP MUTU FISIK DAN EFEKTIVITAS TABIR SURYA EMULGEL KOMBINASI OCTINOXATE-AVOBENZONE Lidya Ameliana; Viddy Agustian Rosyidi; Dwi Nurahmanto; Yudi Wicaksono; Lita Putri Ayu Lestari
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 2 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i2.683

Abstract

Avobenzone and octinoxate are often used as a combination of organic UV filters in sunscreen. At high exposure to UV light, these UV filters can be degraded so that their sunscreen’s effectiveness is reduced. Several studies reported that the combination of plant extracts with synthetic UV filters could increase sunscreen's SPF. Mango leaves contain high levels of flavonoids and in several studies have been shown to have photoprotective activity with good Sun Protection Factor (SPF) values. The Manalagi mango plant is a type of mango that is widely planted in yards, so it's easy to get the raw materials. This study aims to determine the effect of manalagi mango leaf extract with a concentration of 1, 3, and 5% on the physical quality (pH, viscosity, spreadability) and sunscreen activity (SPF, %TE, %TP) of sunscreen emulgel containing avobenzone and octinoxate. This study showes that increasing the concentration of manalagi mango leaf extract reduced the pH and viscosity of the preparation, and significantly increased the spreadability of all formulas. Besides that, it can also increase the SPF value and decrease the %TE and %TP values. The emulgel formula that had the highest sunscreen activity was F3 with an extract concentration of 5%, had an SPF value of 30.597 ± 0.600, %TE 0.0001 ± 0.0001, and %TP 0.0038 ± 0.0016.
Enhancing Photoprotective Performance of Sunscreen Lip Tint Through Factorial Design Optimization of Naringenin and Titanium Dioxide Eryani, Mikhania Christiningtyas; Azizah, Fatiya; Ameliana, Lidya; Sari, Lusia; Ryad Alati
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 11 No. 1 (2026)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v11i1.44130

Abstract

The sun emits various types of radiation, including ultraviolet (UV) radiation, which can damage skin structure, triggering premature aging, irritation, sunburn, and pigmentation disorders. Naringenin and titanium dioxide are known to have protective effects against UV radiation. This study aimed to evaluate the effects of naringenin and titanium dioxide concentrations and their interactions on the physical quality and in vitro sunscreen efficacy of lip tint formulations, and to determine the optimal formulation using Design-Expert software. This study is the first to optimize lip tint sunscreen using factorial design with naringenin and TiO₂.The results showed that the optimal formulation achieved an SPF of 38.23, %TE of 0.0562, and viscosity of 16,166 mPas at 2.1% naringenin and 10% titanium dioxide. Furthermore, higher concentrations of both active ingredients increased the SPF value and decreased the %TE and %TP values. Statistical analysis using a one-sample T-test showed no significant difference between the predicted and experimental results (p > 0.05), confirming the validity of the optimization model.