Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

1.686

P-Index

This Author published in this journals

All Journal e-Journal Pustaka Kesehatan Pharmaciana: Jurnal Kefarmasian STOMATOGNATIC- Jurnal Kedokteran Gigi Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) INDONESIAN JOURNAL OF PHARMACY UNEJ e-Proceeding IDJP (Indonesian Journal of Pharmaceutics) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Kesehatan Islam : Islamic Health Journal Jurnal Ilmu Kefarmasian Indonesia Kartika : Jurnal Ilmiah Farmasi Journal of Tropical Pharmacy and Chemistry Journal of Agropharmacy Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan

Ameliana, Lidya

Unknown Affiliation

Author-ID : 749975

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 31 Documents Claim Missing Document

Claim Missing Document

Articles

1 2 3 4

Optimasi Asam Glikolat dan Asam Sitrat dalam Krim Tabir Surya Kombinasi Titanium Dioksida, Avobenzone dan Octyl Methoxycinnamate desy diana sari; Lidya Ameliana; Dwi Nurahmanto
Pustaka Kesehatan Vol 8 No 3 (2020): Volume 8 No. 3, 2020
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v8i3.12266

Ultraviolet (UV) radiation is the main cause of sunburn and skin cancer. The adverse effects of UV radiation are solved by sunscreen as protection for longer outdoors. In this study, optimization of glycolic acid and citric acid in sunscreen cream combination of titanium dioxide, avobenzone, and octyl methoxycinnamate were investigated using simplex lattice design method. The sunscreen cream evaluation includes physicochemical testing (organoleptic, homogeneity, emulsion type, spreadability, viscosity, and pH) and sunscreen effectiveness (SPF, % erythema transmission, and % pigmentation transmission). The value of physicochemical testing are 5,96 cm - 6,3 cm of spreadability testing; 83,33 dPa.s – 108,33 dPa.s of viscosity testing; 4,06 – 4,67 of pH testing. The value of sunscreen effectiveness are 9,79 – 13,35 of SPF testing; 4,55x10-06 - 0,15x10-06% of % erythema transmission; 5,77 – 7,16 % of % pigmentation transmission. The optimum formula was obtained by combining glycolic acid 2% and citric acid 0% with a desirability value of 0,649.

Pengaruh Propilen Glikol dalam Patch Dispersi Padat Ketoprofen terhadap Karakteristik Fisika Kimia dan Laju Penetrasinya Lidya Ameliana; Haris Raudhatuzakinah Dwiputri; Dwi Nurahmanto
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7572

Ketoprofen is a non steroid anti-inflammatory drug (NSAID) used as analgesic and anti-inflammation. This research had been done by ketoprofen patch preparation and evaluations aiming to enhance its penetration through the skin using propylene glycol as penetration enhancer. Evaluations included homogenity testing and FTIR for ketoprofen solid dispersion and organoleptic, weight uniformity, thickness, folding endurance, surface pH, moisture content, and penetration rate assay of ketoprofen patch. Penetration rate was determined by paddle type dissolution and the sample was analyzed by spectrophotometry UV-Vis. The value of moisture content and penetration rate were analyzed by One Way ANOVA with confidence level of 95 %. The value of moisture contents were F0 1.17 ± 0.0551 %; F1 1.27 ± 0.0208 %; F2 1.33 ± 0.08 %; and F3 1.43 ± 0.0208 %. The penetration rates of ketoprofen were F0 0.5258 ± 0.0191 µg/cm2.minute; F1 0.6935 ± 0.0613 µg/cm2.minute; F1 0.6935 ± 0.0613 µg/cm2.minute; and F3 1.1260 ± 0.0850 µg/cm2.minute. It can be concluded that the formula with propylene glycol 150 mg/patch can deliver the best penetration rate and moisture content that were fullfill the requirements. Keywords: ketoprofen, patch, propilen glikol, penetratio enhancer, solid dispersion

Pengaruh Komposisi Hidroksi Propil Metil Selulosa K-15 dan Etil Selulosa N-22 terhadap Prosentase Kelembapan Air dan Pelepasan Meloksikam dari Sediaan Plester (The Influence of Hidroxy Propyl Methyl Cellulose K-15 and Ethyl Cellulose N-22 Ratio on Procent Monica Iwud Rully Pramesthie; Lidya Ameliana; Budipratiwi Wisudyaningsih
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

The present research has been undertaken with the aim to develop a transdermal patch of meloxicam with ratio of hydroxy propyl methyl cellulose (HPMC) K-15 and ethylcellulose (EC)N-22 as a matrix were 1:9 (Formula 1), 2:8 (Formula 2), 3:7 (Formula 3).The physicochemical parameters like organoleptic and % moisture content were evaluated. Released test using dissolution apparatus were carried out in 500 mL of phosphate buffer saline pH 7.4 ± 0.05 at temperature 37 ± 0.5°C with speed of swirl 50 rpm. Results were analyzed by statistic programmed of SPSS using one way analysis of variance with degree of believed 95% (α = 0,05).The results of evaluation of patch dosage, transdermal patches were found yellow, odorless and dry. Result of moisture content F(1) 1.168 ± 0.009 %; F(2) 1.841 ± 0.019 % and F(3) 2.584 ± 0.025 %. Result of in vitro drug release F(1) 364.865 ± 0.701 µg/cm2.menit1/2; F(2) 397.212 ± 0.441 µg/cm2.menit1/2 and F(3) 439.277 ± 0.559 µg/cm2.menit1/2. It can be concluded that the combination ofHPMC K-15 and EC N-22 at ratio 7:3 was the best choice for manufacturing transdermal patch based on physicochemical and the release profile. Keywords: transdermal patch, meloxicam, hydroxypropylmethyl celulosa, ethylcellulosa

INFLUENCE OF OLEIC ACID ON THE IN VITRO PENETRATION OF DICLOFENAC SODIUM GEL Lidya Ameliana; Esti Hendradi; Mochammad Yuwono
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Diclofenac sodium (DS) is a nonsteroidalantiinflammatory drugs (NSAIDs), that inhibitscyclooxygenase-2 enzyme (COX-2). It has first passmetabolism by 40-50%, because of its shortbiological half-life, the drug has to be givenfrequently (Ganiswara, 2005). Dose of DS in gel is 1%(Sweetman, 2007). In peroral use, it may cause therisk of gastrointestinal bleeding, cardiovascular,hypersensitivity reactions and disorders of thecentral nervous (Katzung, 2002, Chuasuwan, et al.,2008).DS does not penetrate well through skin and cannotreach the effective concentration at the site ofaction after transdermal application (Mohammed,2001; Ozguney, et al., 2006). DS partition coefficientin n-octanol-buffer aqua (log P) was 1.1 (Chuasuwan,2008). Lipophilic nature of the stratum corneum andthe hydrophilic nature of the underlying tissuesshowed that the drug will penetrate the skin shouldhave an optimal balance between the lipophilic andhydrophilic properties. In general, the skin is morepermeable to the material which has a partitioncoefficient (P) in octanol-water between 10-1000(Michniac-Kohn et al., 2005).Oleic acid enhances the penetration of drugs intothe skin by increasing the fluidity of the stratumcorneum lipids through the establishment ofchannels (water channels) (Fang , et al , 2003)This study aimed to know the influence of OleicAcid (OA) in several concentrations (1%, 3% and5%) as penetration enhancer on the in vitropenetration of topical DS gel. Furthermore, thephysical properties of the topical preparation(organoleptic, pH and viscosity), and DS penetrationpercutaneously through rat skin . Then observedthat in spite of DS assay and penetrate through therat skin at certain intervals and observed by meansof HPLC.

The Effect of Citronella Oil Concentration (Cymbopogon nardus (L. ) Rendle) on the Quality of Shampoo and Antifungal Activity of Candida albicans Lidya Ameliana; Alik Almawadah; Lestyo Wulandari
Indonesian Journal of Pharmaceutics Vol 1, Issue 2, May - August 2019
Publisher : Universitas Padjadjaran (Unpad)

Citronella oil (Cymbopogon nardus (L.) Rendle) was formulated into shampoo preparations to overcome dandruff. Dandruff is a condition which exfoliation of the excess horny layer on the scalp and forms fine scales caused by fungal infections of Candida albicans. The purpose of this study was to determine the antifungal activity and quality of the citronella oil shampoo. Citronella oil was taken using a steam distillation method. The oil produced has good quality because it meet the range of organoleptic requirements, which were the refractive index 1.483, density 0.890g/mL and citronellal content 41.720%. MIC (Minimum Inhibition Concentration) to find out the lowest concentration of shampoo which can still inhibit the growth of Candida albicans was 2%. Citronella oil then formulated into shampoo with F1 (4%) F2 (6%) and F3 (8%) oil concentrations. The results of the quality of shampoo evaluation showed that all formulations met the requirements of pH, viscosity, and foam height. In testing the antifungal activity of shampoo was known that the greater the concentration of oil in the shampoo, the greater the antifungal activity in the shampoo.Keywords: Citronella oil, shampoo, antifungal activity

PENGARUH PENAMBAHAN ASAM LAKTAT SEBAGAI ENHANCER TERHADAP PENETRASI PERKUTAN KAFEIN DALAM BASIS GEL Lidya Ameliana; Lusia Oktora RKS; Devi Dwi N
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 10 No 2 (2013)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Caffeine is a drug which is effective as an anti-cellulite. Caffeine works by slowing down the lipogenesis process and accelerating the lipolysis process. In this research, caffeine was formulated in Sodium CMC gel base and lactic acid (0, 2, 4, and 6%) as enhancers. The aims of these research was to know the effects of lactic acid as enhancer on pH, viscosity, spreadibility, flowability properties, and percutaneous penetration study of caffeine gel. The results obtained that all formulas have fullfilled of all requirements and it can be concluded that lactic acid lowered the pH, increased viscosity, and lowered spreadibility. The highest flux was obtained the caffeine gel on concentration of 6% lactic acid is equal to 5.43 g/cm2 menit.

PENGEMBANGAN FORMULA KRIM MINYAK SEREH (Cymbopogon citratus) SEBAGAI ANTI NYAMUK TOPIKAL Lidya Ameliana; Evi Umayah Ulfa
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 9 No 1 (2012)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Volatile oils extracted by steam distillation from Cymbopogon citratus were formulated in creams. Theessential oils were then employed as active ingredients in the preparation of insect repellents used in our field trials.These creams containing 0%; 0,5%; 1%; 5%; 10% and 15% (w/w) of volatile oil from Cymbopogon citratus. Thesecreams were evaluated in physical qualities like appearance, pH, spreadibility, and viscosity. And also wereevaluated for their repellency effect against adult female mosquitoes of Aedes aegypti. Results from the field trialsindicate that cream containing 10% of the essential oil from Cymbopogon citratus provided 1071 ± 26.514 seconds ofprotection time against mosquito bites. And the cream containing 15% of the essential oil from Cymbopogoncitratus provided 1097.333 ± 19.139 seconds. It means cream containing 15% of the essential oil is the best formula ofrepellent cream, but does not significantly with cream containing 10 % of the essential oil

Pengembangan Essence dari Ekstrak Kayu Secang (Caesalpinia sappan L.) Lidya Ameliana; Budipratiwi Wisudyaningsih; Dwi Nurahmanto; Yenika Ayu Mega Dianatri
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 1 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i1.1139

Sappan wood (Caesalpinia sappan L.) was reported to have natural antioxidant properties. Brazillin is the compound responsible for its antioxidant effect. Antioxidants are needed to prevent premature aging of the skin. Essence is a cosmetic that contains topical antioxidants. Essence has advantages over other skincare products, and essence is easier to absorb into the skin. The objective of the present study was to optimize and evaluate the Essence of sappan wood ethanolic extract for treatment as a cosmetic antioxidant. Simplex lattice design was adopted to evaluate the effect of butylene glycol and glycerin concentration on Essence characteristics. The method used in the extraction is maceration with ethanol solvent. The results showed that both butylene glycol and glycerin significantly enhanced the viscosity and pH value of the sappan essence formulation. The optimum Essence formula consisted of 10% butylene glycol with a predicted viscosity value of 2,944 dPas and a pH of 5,075. The characteristics of the optimum formula of sappan wood extract Essence have a thick texture, a characteristic odor of colored extract brownish yellow, homogeneous, and has a spreadabillity of 14 cm.

Optimasi Titanium Dioksida Dan Asam Glikolat Dalam Krim Tabir Surya Kombinasi Benzofenon-3 dan Oktil Metoksisinamat Viddy Agustian Rosyidi; Wirawan Deni; Lidya Ameliana
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 15 No. 01 Juli 2018
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Sinar ultraviolet (UV) memiliki dampak buruk, yaitu sinar UV-A mampu menyebabkan pigmentasi dan sinar UV-B mampu menginduksi eritema, melanogenesis, kerusakan DNA, dan karsinoma sel skuamosa. Dampak buruk sinar UV terhadap kulit dapat diatasi dengan penggunaan tabir surya. Pada penelitian ini dilakukan penentuan formula optimum dari kombinasi titanium dioksida dan asam glikolat pada krim tabir surya terhadap beberapa respon, yaitu pH, viskositas, SPF, % transmisi eritema, dan % transmisi pigmentasi dengan rancangan formula desain faktorial. Empat formula krim tabir surya telah dibuat dengan perbedaan pada proporsi titanium dioksida dan asam glikolat. Formula optimum yang terpilih adalah kombinasi titanium dioksida dan asam glikolat dengan proporsi 1% : 0,5% yang memberikan prediksi respon paling baik.

Optimasi Jumlah Hidroksipropil Metilselulosa dan Lama Pengadukan dalam Preparasi Hollow Microspheres Captopril Eka Deddy Irawan; Firdatus Sholehah; Lidya Ameliana
Pustaka Kesehatan Vol 10 No 2 (2022): Volume 10 No.2, 2022
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v10i2.11913

Captopril is an antihypertensive class of Angiotensin-Converting Enzyme Inhibitor (ACEI) used as one of the treatment of hypertension. Low bioavailability and short half-life of captopril caused side effects on gastrointestinal tract, thus it can be prepared into hollow microspheres. Hollow microspheres is spherical microparticles with 1-1000 µm hollow nucleus. Many factors influence the preparation of hollow microspheres including the amount of hydroxypropyl methylcellulose (HPMC) polymer and stirring time. In this study we investigated the best composition of the number of HPMC and stirring times which can produce captopril hollow microspheres with entrapment efficiency (EE), buoyancy, and optimum particle size. Hollow microspheres captopril was prepared using a non-aquoeous solvent evaporation method. The result was captopril hollow microspheres with 25 mg HPMC and 2 hours of stirring can produce an entrapment efficiency (EE) 97,796%, buoyancy 86,747% and particle size 205,655 µm. The yield hollow microspheres captopril 91.903% ± 2.547 with spherical shape, uneven surface morphology and hollow core. The results of FT-IR analysis showed that there was no interaction between the drug and the polymer used in the formulation.

Co-Authors Alik Almawadah Arafika, Whendy Waliya Aslyni Putri Suranina Barus Budipratiwi Wisudyaningsih desy diana sari Devi Dwi N Devi Dwi N, Devi Dwi Nurahmanto Dwi Nurahmanto Dwi Nurrahmanto Eka Deddy Irawan Elok Rimadani Esti Hendradi Evi Umayah Ulfa Evi Umayah Ulfa Farkha, Fara Sukma Firdatus Sholehah Fitri Wazni Friska Wira Sabrina Gazzali, Amirah Mohd Haris Raudhatuzakinah Dwiputri Indarto Adikusumo Kristine Dwi Puspitasari Kuni Zu’aimah Barikah Lestyo Wulandari Lina Winarni Lina Winarti Lina Winarti Lita Putri Ayu Lestari Lusia Oktora RKS Lusia Oktora RKS, Lusia Lusia Oktora Ruma Kumala Sari maarif, safirul Mochammad Yuwono Monica Iwud Rully Pramesthie Nurahmanto, Dwi Nurul Qomariyah Nurul Shalikha Paramayuda, Farukh Putri Mustika Nandani Rizka Kurnia Cetika Roja, Talidah Alqibtiyah Sabrina, Friska Wira Sabrina, Friska Wira Selly Rio Wardhani Shalikha, Nurul Tanfidz Alishlah, Tanfidz Viddy Agustian Rosyidi Wirawan Deni Yenika Ayu Mega Dianatri Yudi Wicaksono

Title

Found 31 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 31 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 31 Documents
Search