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All Journal JMM (Jurnal Masyarakat Mandiri) Jurnal Penelitian Farmasi dan Herbal Jurnal Farmasi Generics: Journal of Research in Pharmacy Abadi: Jurnal Ahmad Dahlan Mengabdi Jurnal Pengabdian Masyarakat Bangsa Journal of Business Management ABDI UNISAP: Jurnal Pengabdian Kepada Masyarakat Generics : Journal of Research in Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Sakti, Aditya Sindu
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Review: Modern Extraction Methods for Extraction Proanthocyanidins from Natural Products Manzil, Li’izzah Diana; Sakti, Aditya Sindu
Generics: Journal of Research in Pharmacy Vol 6, No 1 (2026): Generics : Journal of Research in Pharmacy
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v6i1.28200

Abstract

Proanthocyanidins are widely distributed in many plant species and are recognized for their beneficial health effects, particularly their antioxidant and anti-inflammatory activities. This literature review aims to evaluate modern extraction techniques used to isolate proanthocyanidins from natural sources. Conventional methods, such as maceration and Soxhlet extraction, often result in reduced yields because proanthocyanidins are heat-sensitive and susceptible to oxidation. To address these limitations, this review explores alternative modern extraction approaches. Relevant peer-reviewed articles were identified through a comprehensive search of five academic databases: ScienceDirect, PubMed, Google Scholar, NCBI, and BMC. The modern extraction techniques examined include Ultrasound-Assisted Extraction (UAE), Microwave-Assisted Extraction (MAE), Enzyme-Assisted Extraction (EAE), and Pressurized Liquid Extraction (PLE). Evidence from 23 selected studies shows that UAE and MAE are among the most effective and efficient methods for extracting proanthocyanidins from natural matrices. These findings underscore the potential of modern extraction technologies to improve both the yield and quality of proanthocyanidins, supporting their broader application in pharmaceutical and nutraceutical fields.
IMPLEMENTASI MIKROBIOLOGI FARMASI, UPAYA PENCEGAHAN DAN PENANGANAN DINI DEMAM BERDARAH MELALUI KEGIATAN PENYULUHAN DI LAMONGAN Sakti, Aditya Sindu; Octavia, Devi Ristian; Sari, Popy Dwi Permata; Fadhila, Salsabila Nur; Wibowo, Alfina Wijayanti; Sholichatin, Haeny; Akhyar, Miftakhul; Maharani, Tiara Anisa; Lutfiana, Era; Putri, Amalia Winanda
JMM (Jurnal Masyarakat Mandiri) Vol 8, No 2 (2024): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v8i2.22249

Abstract

Abstrak: Dusun Pereng, Lamongan merupakan dusun yang memiliki banyak sawah tambak sehingga rentan terjadinya KLB demam berdarah, pengetahuan masyarakat terkait upaya pencegahan dan penanganan dini demam berdarah dapat menurunkan kejadian dan keparahan demam berdarah . Kegiatan penyuluhan ini bertujuan untuk meningkatkan pengetahuan ibu rumah tangga di Dusun Pereng, Lamongan mengenai upaya pencegahan dan penanganan demam berdarah dengan memanfaatkan potensi herbal unggulan desa. Mitra yang terlibat dalam kegiatan penyuluhan ini adalah ibu rumah tangga di RT 01 RW 03, Dusun Pereng, Lamongan sebanyak 12 orang . Metode yang digunakan adalah penyuluhan dengan bantuan media visual berupa poster, evaluasi perubahan tingkat pengetahuan mitra dilakukan dengan menggunakan kuesioner pre-test post-test. Peningkatan pengetahuan secara signifikan (p>0.05) hanya terjadi pada 42% mitra ibu rumah tangga. Peningkatan pengetahuan mitra dengan metode penyuluhan kurang memberikan pengaruh yang bermakna terhadap pengetahuan mitra mengenai upaya pencegahan dan penanganan demam berdarah.Abstract: Pereng is a village in Lamongan that has many ponds so it is prone to outbreaks of dengue fever. Public knowledge about prevention and early treatment of dengue fever can reduce the incidence and severity of dengue fever. This educational health campaign aims to increase the knowledge of housewives in Pereng, Lamongan regarding the prevention and treatment of dengue fever by utilizing the potential of the village's superior herbs. The partners involved in this educational health campaign were 12 housewives in RT 01 RW 03, Pereng village, Lamongan. The method used is an educational health campaign using the visual media of poster. Evaluation of the level of knowledge from housewife respondents was performed using a pre-test post-test questionnaire. A significant increase in knowledge (p>0.05) only occurred in 42% of housewife respondents. Increasing partners' knowledge using outreach methods performed did not have a significant influence on the knowledge of housewife respondents. 
Co-Authors ABDUL ROKHMAN Adhimi, Cici Sayyidatul Ainun Syajidah, Hanna Akhyar, Miftakhul Al-Hadi, Muhammad Muflih Zaki Ambar Pramudita, Galuh Amran Nur Anggaraini, Yessy Puspa Arrofiqi, Mochammad Rasyad Astria, Nikita Bambang Tjiroso, Bambang Chalid, Nurdin Dihir, Sri Defi Dudi Amarullah Fachry Abda El Rahman Fadhila, Salsabila Nur Firdiyansyah, Moh. Rofiqi Fransisca Dita Mayangsari Imtiyaaz, Moh Thaariq Zelda khusnul khotimah Krois, Adysabzan T. Kusumo, Djati Wulan Lutfiana, Era Maharani, Tiara Anisa Manzil, Li’izzah Diana Mentari, Merry Anggelya Miftah, Siraj Nur Rafi Muhammad Nurul Fadel Muhlis, Widyawati Novitasari, Laela Nurin, Eka Filza Octavia, Devi Ristian Putri, Amalia Winanda Rachman, Eva Syariefah Rope, Mohammad Reza Vitra Sandrawati, Sandrawati Sari, Popy Dwi Permata Setianingsih, Elfrida Rosselly Sholichatin, Haeny Siregar, Khoiryah Miagori Siti Mutamimah, Siti Sri Bintang Sahara Mahaputra Kusumanegara Wibowo, Alfina Wijayanti Yulimanida, Herri Zuhri, Mukhammad Syaifuddin