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Journal : VALENSI

A New Antiplasmodial Compound from the Papuan Marine Sponge Xestospongia sp. Murtihapsari Murtihapsari; Amir M Suruwaky; Kadarusman Kadarusman; Dikdik Kurnia; Tati Herlina; Unang Supratman
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 4, No. 1, Mei 2018
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (432.864 KB) | DOI: 10.15408/jkv.v4i1.6735

Abstract

A new antiplasmodial compound, 2-(3H-diazirine-3-yl)benzaldehyde (1), has been isolated from the Papuan marine sponge Xestospongia sp. The structure elucidation of compound 1 was determined by spectroscopic evidences including UV, IR, MS, 1D and 2D-NMR analysis. Compound 1 showed moderate antiplasmodial activity against Plasmodium falciparum with IC50 value of 1.08 x 10-6 mM. DOI:http://dx.doi.org/10.15408/jkv.v4i1.6735