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All Journal MPI (Media Pharmaceutica Indonesiana) Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Pengabdian Kepada Masyarakat Sisthana Bencoolen Journal of Pharmacy Science and Community Pharmacy Journal
Sa’adah, Anifatus
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Science and Community Pharmacy Journal

 1 
Total Flavonoid Content (TFC) and Antioxidant Activity of Carrot Extract Isolate (Daucus carota L.) Nadiya Nihlatunnaja; Kalsum, Ummi; Sa’adah, Anifatus
Science and Community Pharmacy Journal Vol. 2 No. 1 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i1.356

Abstract

Antioxidants are antiradical compounds that can neutralize reactive free radicals into non-reactive ones that are relatively more stable so as to protect cells from the harmful effects of free radicals. Carrots have antioxidant activity due to the presence of carotenoid compounds. This study aims to determine the antioxidant activity of carrots. Extraction research method with maceration method. Isolation of flavonoids by column chromatography method. Antioxidant activity test using FRAP method. The results of research conducted from 60 extract fractions obtained 10 flavonoid fractions with a %TFC value 5,332%; 5,242%; 6,742%; 7,475%; 6,829%; 5,896%; 5,282%; 6,191%; 5,450%; and 5,498%. IC50 3,920; 1,960; 2,096; 2,065; 1,846; 0,867; 3,517; 1,179; 3,383; dan 3,570 ppm. In conclusion, the antioxidant activity of the ten fractions was very strong (<50 g/mL).
Stability Testing Occurred On Piroxicam Cream Preparation By Using Stearic Acid And Triethanolamine As Emulsifying Agents Aldila, Silvy; Girsang, Valentina; Rahmawati, Ina Sonia; Maharai, Daniel; Sa’adah, Anifatus
Science and Community Pharmacy Journal Vol. 2 No. 2 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i2.482

Abstract

Preface: Piroxicam is classified as a Class 2 product in the Biopharmaceutic Classification System due to its limited solubility in water. The cream preparations underwent optimisation of the stearic acid and triethanolamine concentrations. The optimisation results indicate that the most favourable amounts of stearic acid and triethanolamine (TEA) are 16% and 4% respectively. The physical attributes test yielded positive findings for the formula, indicating a successful cream formulation that satisfied the specified criteria. Purpose: The cream formulation is thereafter submitted to a stability assessment. The purpose of the stability test is to ascertain the long-lasting quality of the preparation when subjected to various storage circumstances. Procedure: Stability tests were conducted over 6 cycles at temperatures of 4° C and 40° C. During the testing phase, various characteristics of the cream preparation were assessed, including organoleptic properties, homogeneity, viscosity, adhesive power, spreadability, and pH. Result: The formulated solution successfully fulfils the criteria of the physical characteristics test, with the following parameter values: pH of 6.8, viscosity of 11010 Cps, spreading power of 6.8 cm, adhesive power of 2.6 seconds, and protective power of 6.5 seconds. Conclusion: The t-test findings conducted before and after assessing the stability of the preparation indicated a p-value greater than 0.05, indicating the absence of a significant difference.
BROCCOLI (Brassica oleracea L) ETHANOL EXTRACT: A MOISTURIZER AND ITS EVALUATION IN ASPECTS OF PHYSICAL CHARACTERISTICS Aldila, Silvy; Puruhita, Ranatri; Uliana, Syahkhirotul Exma; Sa’adah, Anifatus; Gloria, Fransisca
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.545

Abstract

Skin disorders that are dry, dull, scaly, and not fresh affect everyone. Moisturizing cream is a cosmetic product that effectively hydrates and improves dry skin. Broccoli, scientifically known as Brassica oleracea L, is rich in vitamin C components, vitamin E (α-tocopherol), and flavonoids, which act as natural antioxidants and provide moisturizing properties for the skin. Producing extracts by the maceration process. Broccoli extract is utilized in the formulation of four moisturizing cream preparation compositions, each with a concentration of F1 (0%), F2 (2%), F3 (3%), and F4 (4%). The moisturizing cream formulation is assessed for its physical properties. Conducting tests to evaluate the dosage characteristics of moisturizing creams, includes organoleptic testing, homogeneity testing, pH testing, dispersion testing, adhesion testing, and viscosity testing. The concentration of broccoli extract in the four moisturizing cream preparation formulations is as follows: F1 (0%), F2 (2%), F3 (3%), and F4 (4%). The moisturizing cream formulation is assessed for its physical properties. Conducting tests to evaluate the dosage properties of moisturizing creams, including sensory evaluation, uniformity assessment, pH measurement, dispersion analysis, adhesion examination, and viscosity measurement
Co-Authors Adrianto, Madyo Aldila, Silvy Anak Agung Pradnya Paramitha Vidiani Anisa Devi Kharisma Wibowo Dahliyanti, Novita Dwi Girsang, Valentina Gloria, Fransisca Kusuma Dewi, Liestyani Maharai, Daniel Nadiya Nihlatunnaja Noer'aini, I'ien Ovikariani Ovikariani, Ovikariani Puruhita, Ranatri Rahmawati, Ina Sonia Rustaman, Heri Sri Suwarni Sulistyaningrum, Danny Putri Tapun, Margareta Chintami Uliana, Syahkhirotul Exma Ummi Kalsum Yuliasari, Niken