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Arif, Fahrudin
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Workshop on Natural Medicine Ingredients for Digestive System Disorders Wibowo, Teguh Setiawan; Arif, Fahrudin; Pramono, Joko; Firdiansyah, Moh. Rofiqi; Ardiansyah, M. Yusuf; Purwantoro, Guntur
Jurnal Pengabdian Masyarakat Bestari Vol. 3 No. 12 (2024): December 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/jpmb.v3i12.12662

Abstract

Traditional medicine is an ingredient or a combination of ingredients in the form of plant materials, animal materials, mineral materials, preparation of sarian (galenik) or a mixture of these materials that have been used for generations for treatment and can be applied in accordance with the norms prevailing in the community. One of the basic needs of living things is food and health. Food is needed by living things as a source of energy, therefore the food consumed must contain substances needed by the body, such as carbohydrates, proteins, fats, vitamins, minerals, and water. The digestive system in humans is a series of processes to convert food by breaking down complex food molecules into simple ones with the help of enzymes and absorbing the food essence needed by the human body. So that digestive system disorders greatly affect the human health system. The method used is presentation, question, answer, discussion and assistance (in the form of practice and evaluation) with preparation carried out for 2 weeks.
PENGARUH PELARUT PROPILENGLIKOL-SORBITOL PADA SIFAT FISIK DAN KADAR ZAT AKTIF SIRUP PARASETAMOL Arif, Fahrudin
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 1 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i1.7881

Abstract

Sirup adalah sediaan pekat dalam air dari gula atau pengganti gula dengan atau tanpa penambah bahan pewangi dan zat obat. Parasetamol merupakan bahan obat yang agak sukar larut dalam air, sehingga diperlukan teknik khusus untuk melarutkan, kombinasi pelarut campur adalah salah satu teknik untuk melarutkan parasetamol. Tujuan penelitian ini untuk mengetahui pengaruh kadar propilenglikol dan sorbitol sebagai bahan penambah kelarutan pada sifat fisik dan kadar zat aktif sirup parasetamol. Propilenglikol dan sorbitol yang digunakan pada penelitian ini dengan kadar formula I (propilenglikol 20% - sorbitol 10%), II (propilenglikol 15% - sorbitol 15%), III (propilenglikol 10% - sorbitol 20%). Selanjutnya sediaan dievaluasi fisik berupa organoleptis, pH, bobot jenis, kekentalan dan kejernihan dan pengukuran kadar sirup parasetamol. Hasil penelitian organoleptis ketiga formula tidak berwarna karena tidak diberi pewarna, rasa manis, dan tidak berbau. Nilai pH F1 6,50; F2 6,24 dan F3 5,18. Hasil bobot jenis F1 1,2165; F2 1,2308 dan F3 1,2613. Hasil kekentalan F1 184,662 cps; F2 195,612 cps dan F3 203,716 cps. Selanjutnya, pengukuran kadar sirup parasetamol menggunakan spektrofotometer UV pada panjang gelombang 244 nm adalah sebesar 107,076%; 95,38% dan 78,128%. Hasil uji anava dari kadar sirup parasetamol menunjukkan ada perbedaan yang bermakna karena Fhitung (44,028) ≥ Ftabel (3,26) dan adanya pengaruh kadar propilenglikol – sorbitol Pada sifat fisik dan kadar zat aktif sirup parasetamol.
Peningkatan Kapasitas Wirausahawan Pemula dalam Produksi dan Pemasaran Obat Bahan Alam Wibowo, Teguh Setiawan; Arif, Fahrudin; Pramono, Joko; Firdiansyah, Moh. Rofiqi; Purwantoro, Guntur; Eka Putri, Radya Rahma Desy
Jurnal Pengabdian West Science Vol 4 No 03 (2025): Jurnal Pengabdian West Science
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/jpws.v4i03.2099

Abstract

Wirausaha di bidang obat bahan alam memiliki potensi besar dalam mendukung kesehatan masyarakat serta menggerakkan perekonomian lokal. Namun, banyak wirausahawan pemula menghadapi tantangan dalam produksi yang sesuai standar, pemasaran yang efektif, serta kepatuhan terhadap regulasi. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan kapasitas wirausahawan pemula dalam aspek produksi dan pemasaran obat bahan alam melalui pelatihan dan pendampingan. Metode yang digunakan meliputi seminar edukatif, pelatihan praktik produksi berbasis standar keamanan dan kualitas, serta strategi pemasaran digital dan konvensional. Hasil kegiatan menunjukkan adanya peningkatan pemahaman peserta terhadap proses produksi yang sesuai dengan standar BPOM, strategi branding, serta pemasaran berbasis teknologi. Diharapkan, kegiatan ini dapat menjadi langkah awal dalam membangun ekosistem wirausaha obat bahan alam yang berdaya saing dan berkelanjutan.
Aktivitas Antibakteri Kombinasi Ekstrak Etanol Kulit Jeruk Manis (Citrus sinensis) Dan Daun Pepaya (Carica papaya L.) Terhadap Bakteri Salmonella typhi Penyebab Tipes Wijaya, Nadela Wahyu; Fadel, Muhammad Nurul; Arif, Fahrudin
Jurnal Impresi Indonesia Vol. 4 No. 6 (2025): Indonesian Impression Journal (JII)
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i6.6524

Abstract

Salmonella typhi, sweet orange peel, papaya leaves, antibacterial activity, MIC-MICD. AbstractThe background of this study is based on the high incidence of typhoid fever caused by Salmonella typhi bacteria in Indonesia and the increasing resistance of bacteria to conventional antibiotics. Therefore, alternative natural treatments are needed, such as a combination of sweet orange peel extract (Citrus sinensis) and papaya leaves (Carica papaya L.), which are known to contain antibacterial compounds. The objective of this study was to test the antibacterial activity of the ethanol extract combination of the two plants against Salmonella typhi, determine the optimal concentration, and measure the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). The research methods included ethanol extraction, phytochemical testing, disk diffusion testing, and dilution testing. The results showed that the 75%:25% extract combination produced the largest inhibition zone (26.43 mm) with a very strong category, while the MIC and MBC were 6.25% and 25%, respectively. Statistical analysis confirmed significant differences between concentrations. The implications of this study are the potential of the extract combination as a safe and environmentally friendly alternative treatment for typhoid fever, as well as promoting the utilization of local natural resources.
Testing the Effectiveness of Basil Leaf Essential Oil (Ocimum basilicum L) against Aedes Aegypti Mosquitoes in Aromatherapy Candles Rahayu, Santi Dwi; Rahmawati, Riana Putri; Arif, Fahrudin
Advances in Healthcare Research Vol. 3 No. 2 (2025): March - August
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.541

Abstract

Purpose: This study aims to formulate basil leaf essential oil (Ocimum basilicum L.) as an active ingredient against Aedes aegypti mosquitoes in the form of aromatherapy wax that can be applied by inhalation. Research Method: This study is a laboratory experimental study. Essential oil from basil leaves was obtained through steam distillation, while the wax preparation was made using the melting method. The aromatherapy wax formulation consisted of five groups, namely positive control, negative control, formulation I (2%), formulation II (4%), and formulation III (6%). Each formulation was tested through a series of physical property tests, including organoleptic tests (color, odor, and shape), burning time test, melting point test, and effectiveness test as an insect repellent against Aedes aegypti. Data analysis was performed using a one-way ANOVA statistical test and followed by a Tukey Post Hoc test. Results and Discussion: The results showed that aromatherapy candles containing basil essential oil had varying effectiveness against mosquito mortality. Formulations with higher concentrations (4% and 6%) provided the best results in physical testing and biological effectiveness compared to other formulations and controls. Implications: This study supports the development of natural-based aromatherapy candles as a safe, effective, and environmentally friendly alternative insecticide for controlling Aedes aegypti mosquitoes in domestic environments.
Menghidupkan Kembali Ramuan Warisan Leluhur: Pembuatan Parem Kering Tradisional untuk Masyarakat Sehat Wibowo, Teguh Setiawan; Arif, Fahrudin; Lestari, Leni Angga; Mustofa, Mochamad Charis; Dwi Shara, Wahyu Mega
Jurnal Pengabdian West Science Vol 4 No 09 (2025): Jurnal Pengabdian West Science
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/jpws.v4i09.2707

Abstract

Parem kering tradisional merupakan salah satu bentuk kearifan lokal dalam bidang pengobatan tradisional yang telah digunakan turun-temurun untuk menjaga kesehatan dan mengatasi berbagai keluhan fisik, seperti pegal linu, kelelahan, serta menjaga kebugaran tubuh. Namun, perkembangan zaman dan modernisasi membuat praktik pembuatan parem kering secara tradisional mulai ditinggalkan, bahkan kurang dikenal oleh generasi muda. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memperkenalkan kembali teknik pembuatan parem kering tradisional dengan memadukan pengetahuan empiris leluhur dan prinsip kesehatan masyarakat modern. Metode yang digunakan berupa pelatihan langsung pembuatan parem kering menggunakan bahan-bahan alami yang mudah didapat di lingkungan sekitar. Hasil kegiatan menunjukkan bahwa peserta memperoleh keterampilan praktis dalam mengolah bahan herbal menjadi parem kering siap pakai, serta meningkatnya kesadaran masyarakat terhadap pentingnya pemanfaatan ramuan tradisional untuk kesehatan. Dengan demikian, pelatihan ini tidak hanya berfungsi sebagai media transfer pengetahuan, tetapi juga sebagai upaya pelestarian warisan budaya bangsa di bidang kesehatan.
HUBUNGAN FAKTOR PENDIDIKAN TERHADAP PENGETAHUAN DAN PERILAKU PENGOBATAN SWAMEDIKASI DISMENORE Bita Yulia Maharani; Etikasari, Ria; Arif, Fahrudin
Jurnal Kesehatan Tambusai Vol. 6 No. 3 (2025): SEPTEMBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i3.48694

Abstract

Dismenore merupakan salah satu masalah yang umum dialami oleh gadis remaja, gejala yang sering terjadi pada saat dismenore kram di perut bagian bawah yang disertai gejala seperti mual, muntah, pusing, dan sakit kepala. Faktor pendidikan berperan penting dalam menentukan tingkat pengetahuan dan perilaku swamedikasi dismenore tersebut. Penelitian ini bertujuan untuk mengetahui hubungan faktor pendidikan terhadap pengetahuan dan perilaku swamedikasi pada wanita yang mengalami dismenore.. Metode penelitian bersifat observasional kuantitatif dengan pendekatan cross sectional yang dilaksanakan pada bulan Mei 2025. Jumlah subjek penelitian sebanyak 325 responden yang didapat melalui teknik purposive sampling. Kriteria inklusi mencankup : berusia 16 – 27 tahun, menempuh pendidikan SMP, SMA dan tamat SMA, mempunyai pengalaman dismenore, pernah melakukan swamedikasi, dan bersedia menjadi responden telah mengisi kuesioner dan menandatangani lembar informed consent hingga selesai. Hasil responden memiliki pengetahuan dalam kategori cukup sebanyak 70,8 %. Responden yang memiliki perilaku swamedikasi pengobatan dismenore juga dalam kategori cukup 73,5 %. Hasil uji chi-square menunjukkan adanya hubungan yang signifikan antara pendidikan terhadap pengetahuan serta perilaku (p = 0,000) dan hasil uji ANOVA dua jalan juga menunjukan bahwa terdapat hubungan yang signifikan pendidikan terhadap pengetahuan dan perilaku swamedikasi dismenore (p = 0,000). Kesimpulan terdapat hubungan yang signifikan antara faktor pendidikan terhadap pengetahuan serta perilaku swamedikasi dismenore.
PENGARUH KONSENTRASI EKSTRAK KOMBINASI DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) DAN BERAS (Oryza sativa) PADA SEDIAAN KRIM TERHADAP SIFAT FISIK DAN AKTIVITAS ANTIBAKTERI Staphylococcus aureus Rahma, Siti Sofia; Fadel, Muhammad Nurul; Arif, Fahrudin
Jurnal Kesehatan Tambusai Vol. 6 No. 3 (2025): SEPTEMBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i3.49439

Abstract

Diabetes melitus (DM) disebabkan oleh hiperglikemia, metabolisme protein, karbohidrat dan lemak yang tidak normal, sekresi insulin dan juga dapat diakibatkan oleh keturunan atau genetik. Penderita diabetes bila dibiarkan tanpa pengobatan yang tepat dapat memicu berbagai macam komplikasi, diantaranya ulkus diabetikum yang di akibatkan oleh bakteri Staphylococcus aureus. Keparahan pada ulkus diabetikum dapat menyebabkan amputasi. Penelitian ini bertujuan untuk mengevaluasi efektivitas sediaan krim kombinasi daun binahong dan beras dengan konsentrasi ekstrak 5%:15%, 10%:10%, 15%:5% dalam menghambat pertumbuhan bakteri Staphylococcus aureus. Metode penelitian yang digunakan yaitu metode eksperimental dengan pengujian pH, homogenitas, daya sebar, daya lekat dan uji antibakteri dengan difusi cakram. Hasil menunjukkan bahwa formula F3 (15% binahong : 5% beras) memiliki zona hambat antibakteri paling luas (8,9 mm), termasuk kategori sedang, dan nilai pH dalam rentang aman untuk kulit. Formula ini juga memenuhi kriteria fisik sediaan krim topikal. Dengan demikian, kombinasi ekstrak daun binahong dan beras berpotensi sebagai alternatif pengobatan topikal luka infeksi diabetes.
Formulation and Physical Evaluation of Liquid Shampoo Combining Patchouli Leaf Extract and Coconut Oil as an Antidandruff Shampoo Wahyuni, Risma Sri; Hasriyani, Hasriyani; Arif, Fahrudin
Advances in Healthcare Research Vol. 3 No. 2 (2025): March - August
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.516

Abstract

Purpose: Dandruff is a scalp condition that affects approximately 50% of the global population and 26% of the population in Indonesia. This study aims to formulate and evaluate various formulations of liquid shampoo containing a combination of patchouli leaf extract (Pogostemon cablin Benth.) and coconut oil as an alternative natural-based anti-dandruff shampoo. Research Method: This study used a quantitative approach with an experimental design. The formulation consisted of a combination of patchouli leaf extract at concentrations of 0.5%, 0.75%, and 1% and coconut oil at concentrations of 2%, 3%, and 4%. Quality evaluation was conducted through organoleptic testing, homogeneity testing, pH measurement, foam height measurement, viscosity measurement, and skin irritation testing on 15 respondents. Results and Discussion: All formulas (F0, F1, F2, F3) meet the physical quality criteria for shampoo. Organoleptic testing indicates that the formula has a thick liquid consistency, is homogeneous, and ranges in color from clear to dark green, with a green tea aroma. The average pH is within the safe range (6.75–5.31). Foam height and viscosity are within normal limits, and no respondents reported any irritation complaints. Implications: The formulation of liquid shampoo combining patchouli leaves and coconut oil can be a potential solution in the development of safe, natural-based anti-dandruff products. This study provides scientific contributions to the herbal cosmetics industry in Indonesia.
Formulation and Efficacy Test of Antistress Aromatherapy Candle with Jasmine Essential Oil (Jasminum sambac L) on Mice (Mus musculus) Febrianti, Noor Alfina; Rahmawati, Riana Putri; Arif, Fahrudin
Advances in Healthcare Research Vol. 3 No. 2 (2025): March - August
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.521

Abstract

Purpose: Aromatherapy is a non-pharmacological healing method that uses essential oils as therapeutic agents. Jasmine flowers (Jasminum sambac L.) contain active compounds such as linalool, benzyl acetate, methyl salicylate, cis-jasmone, nerolidol, and indole that have potential applications in stress management. This study aims to investigate the antistress efficacy of aromatherapy candles made from jasmine essential oil on mice (Mus musculus). Research Method: This study employed a laboratory experiment with a post-test-only control group design. A total of 25 male mice were divided into five groups, each consisting of five mice. The treatment groups were exposed to aromatherapy candles with essential oil concentrations of 2%, 4%, and 6%, while the control groups included a negative control and a positive control. Stress induction was performed using the Tail Suspension Test (TST), and effectiveness was assessed through immobility time parameters. Data analysis was conducted using a One-Way ANOVA test. Results and Discussion: The results indicate that the wax formula with a concentration of 6% has the best physical characteristics and provides the fastest relaxation effect. The ANOVA test reveals a significant difference between groups (p < 0.05), indicating a significant effect of aromatherapy wax on stress reduction in mice. Implications: This study reinforces the potential of jasmine essential oil-based aromatherapy candles as an alternative therapy for stress management, while also supporting the development of safe and effective, naturally based health products.
Co-Authors AHMAD ROYKHAN Alviona, Juana Della Ardiansyah, M. Yusuf Ari Simbara, Ari Bita Yulia Maharani Chabibah, Chabibah Dwi Shara, Wahyu Mega Eka Putri, Radya Rahma Desy Etikasari, Ria Febrianti, Noor Alfina Firdiansyah, Moh. Rofiqi Fitri Apriliyani GALIH KURNIAWAN Hardiani, Elia Hasriyani Hasriyani, Hasriyani Isnaini, Ratna Dewi Joko Pramono Lestari, Leni Angga Mafitri, Hanifah Miftah Muhammad Nurul Fadel Murharyanti, Rika Mustofa, Mochamad Charis Purwantoro, Guntur Rahma, Siti Sofia Rahmawati, Riana Putri Santi Dwi Rahayu Setyaningrum, Intansari Wahyuni, Risma Sri Wibowo, Teguh Setiawan Wijaya, Nadela Wahyu Zaenal Fanani