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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Farmasi Indonesia JURNAL FARMASIMED (JFM) Jurnal Ners Jurnal Farmasi dan Sains Indonesia (JFSI) Generics: Journal of Research in Pharmacy Jurnal Pharmacopoeia SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT Generics : Journal of Research in Pharmacy Jurnal Sains dan Kesehatan JPEMAS: Jurnal Pengabdian Kepada Masyarakat
Purwaningsih, Avianti Eka Dewi Aditya
Program Studi Profesi Apoteker, Fakultas Farmasi, Universitas Setiabudi, Surakarta, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health

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Evaluasi Penggunaan Obat Antibiotik Secara Kualitatif dan Kuantitatif Pada Pasien Rawat Inap Tonsilitas RS X Surakarta Purwaningsih, Avianti Eka Dewi Aditya; Effendy, Aura Nurul Alfiah; Widyaningrum, Riana
Generics: Journal of Research in Pharmacy Vol 5, No 2 (2025): Generics : Journal of Research in Pharmacy Volume 5, Edisi 2, 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v5i2.25642

Abstract

Tonsilitis suatu kondisi peradangan pada bagian tonsil palatinda, termasuk salah satu bagian dari cincin waldeyer yang sering disebabkan oleh virus Epstein Barr. Infeksi ini ditularkan melalui cairan tubuh (air liur) dan udara (air borne, droplet). Pemberian antibiotik pada nyeri tenggorokan khususnya pada tonsilitis yang tidak sesuai dengan algoritma terapi dapat menimbulkan resistensi bakteri. Penelitian ini bertujuan untuk mengevaluasi penggunaan antibiotik di Rumah Sakit X Surakarta. Penelitian observasional dengan metode probability sampling untuk analisa deskriptif. Penggunaan antibiotika dianalisa kuantitatif (metode ATC/DDD) dan kualitatif (metode Gyssens). Data yang didapatkan dianalisa secara deskriptif kemudian ditampilkan dalam bentuk tabel. Hasil penelitian, penggunaan antibiotik selama bulan Januari – Desember 2023 memiliki nilai DDD sebesar 39,182 DDD. Penggunaan antibiotik paling besar yaitu Cefuroxime dengan nilai DDD/100 hari sebesar 19,705 DDD. Hasil evaluasi secara kualitatif ditemukan ketidakcocokan pada kategori IVA, IVC, IVD, dan IIIB sebanyak 33 kasus (53,2%).
KAJIAN PENGGUNAAN ANTIBIOTIK PROFILAKSIS PADA PASIEN BEDAH CESAR DI RSUD IBU FATMAWATI SOEKARNO KOTA SURAKARTA TAHUN 2020 Purwaningsih, Avianti Eka Dewi Aditya; Chandra, Sherley Widya; Harsono, Samuel Budi
Jurnal Pharmacopoeia Vol 2 No 1 (2023): Maret 2023
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jp.v2i1.352

Abstract

Pemberian antibiotik profilaksis disarankan untuk persalinan sectio caesarea karena terbukti efektif menurunkan angka infeksi luka operasi. Tujuan penelitian ini untuk mengkaji ketepatan dalam pemberian antibiotik profilaksis di RSUD Ibu Fatmawati Soekarno tahun 2020 menggunakan metode Gyssens. Jenis penelitian ini termasuk deskriptif non eksperimental. Pengambilan data secara retrospektif dengan melihat data rekam medik pasien bedah cesar di RSUD Ibu Fatmawati Soekarno tahun 2020. Analisis data dilakukan secara deskriptif yang digunakan untuk mengkaji berupa karakteristik pasien, pola penggunaan antibiotik profilaksis, serta kesesuaian dengan pedoman yang dibandingkan dengan bagan alur Gyssens. Hasil penelitian pada pasien bedah cesar di RSUD Ibu Fatmawati Soekarno tahun 2020 menunjukkan antibiotik yang paling sering digunakan adalah sefuroksim (92,61%), seftriakson (2,96%), ampicillin+sulbaktam (2,46%), ampicillin (1,48%), sefadroksil (0,49%). Kajian penggunaan antibiotik profilaksis berdasarkan Gyssens diperoleh kategori 0 (74,06%), kategori VI (23,68%), dan kategori IVA (2,26%). Rute pemberian intravena sudah sesuai dengan pedoman (100%). Dosis, interval, durasi antibiotik sudah sesuai yaitu penggunaan dosis 1-2g dengan frekuensi 2x sehari, durasi 1-2 hari (100%). Waktu pemberian ≤30 menit (100%).
Antibiotic Use in Inpatients with Diarrhea in Children: A Quantitative Evaluation at Hospital X, Semarang Regency, 2023 Zulfia Widiastuti; Avianti Eka Dewi Aditya Purwaningsih; Amalia Nurul Ulum
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/s8qfqn40

Abstract

Background : Infection remain one of the leading causes of morbidity in tropical regions such as Indonesia, with Escherichia coli being one of the most freequently identified pathogens. The high incidence of Escherichia coli-related infections has led to increased antibiotics use, considering that this commensal gut bactericum can cause both asymptomatic infections and symtomatic diarrhe, either bloody or non-bloody. Objective : This study aimed to evaluate use in pediatric patiens with diarrea at Hospital X, Semarang Regency, in 2023. Methods: This was a retrospective study uutilizing medical records of 323 pediatric patiens who met the inclusion and exclusion criteria. Data analysis was performed using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) methodology. Result:The analysis revealed that Ceftriaxone injection was the most frequently used antibiotic (61.95%), followed by Ampicillin, Amikacin, Gentamicin, and Cefotaxime. Ceftriaxone was often prefered due to its efficacy against both gram-positive and gram-negative bacteria comonly associated with pediatric diarrhea, as well as the advantage of accurate dosing trough injectable formulations. Most diarrhea cases occurred in boys (62.54%) and in children under five years of age (65.63%). Conclusion:Injectable formulations were chosen to reduce the risk of vomiting and to facilitate precise and effective dosing. Evaluation using the ATX/DDD method highlighted the need for more rational antibiotic management to prevent bacterial resistance in the future. Optimizing antibiotic stewardship is crucial to ensure targeted in the future. Optimizing antibiotic stewardship is crucial to ensure targeted, effective use and to preserve therapeutic efficacy in the long term. 
Evaluation Of Antibiotic Use In Diabetic Ulcer Patients Based On The Defined Daily Dose Method (Ddd) As Syifa Roidhotul Jannah Putri Widi; Avianti Eka Dewi Aditya Purwaningsih; Novita Sari
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/8nffcw16

Abstract

Diabetic ulcers are a complication of diabetes mellitus that manifest as open skin wounds on the feet due to blood vessel disorders and nerve damage. These ulcers are susceptible to infection because bacteria thrive in high glucose environments. Selecting the right antibiotic is crucial in treating these infections. This study aims to predict the pattern of antibiotic prescribing in patients with diabetic ulcer infection in Hospital X Semarang Regency in 2023 using the ATC (Anatomical Therapeutic Chemical) method and DDD (Defined Daily Dose) units. This study is a retrospective descriptive study that analyzes data on diabetic ulcer patients who received antibiotic therapy between January-December 2023. The data collection technique was carried out by purposive sampling, following the inclusion and exclusion criteria. The results of the study of 168 patients with Diabetic Ulcers were found to be more dominant in female patients 53.57% (90 patients) and male patients 46.43% (78 patients). The antibiotic research that was classified as having the highest DDD/100 patient-days value was Ceftriaxone 44.99 DDD, followed by Metronidazole 33.96 DDD and Levofloxacin 26.85 DDD. Meanwhile, antibiotics that were included in the DU 90% segment with the order of highest to lowest values ​​were Ceftriaxone (36.16%), Metronidazole (63.46%), and Levofloxacin (85.04%). The use of antibiotics in diabetic ulcer patients based on the ATC/DDD and DU 90% methods needs to be reviewed periodically because it has the potential to cause the risk of resistance in patients which will then prolong the healing process. Based on the evaluation of antibiotic consumption patterns in diabetic ulcer patients at Hospital X, Semarang Regency in 2023 using the ATC/DDD and DU 90% methods, the antibiotics with the highest DDD/100 patient-days were Ceftriaxone (44.99), followed by Metronidazole (33.96) and Levofloxacin (26.85). These three antibiotics are included in the DU 90% segment, therefore their use needs to be periodically evaluated to ensure the rationality of therapy and to prevent the occurrence of antibiotic resistance.
Overview of Antiepileptic Drug (AED) Use in Outpatient Patients at UNS Hospital Maya Nur Ayu Fatdhillillah; Avianti Eka Dewi Aditya Purwaningsih; E. Aprilia L. Tobing
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/5s852a48

Abstract

Epilepsy is a long-term disorder of the nervous system that requires long-term therapy using antiepileptic drugs (AEDs) to control seizures. The proper pattern of AED use plays a significant role in the effectiveness of treatment and patients’ overall well-being. This study aims to describe the use of antiepileptic drugs in outpatient patients at Universitas Sebelas Maret Hospital during the period of January-December 2024. This study used a non-experimental design with a descriptive approach, and data collection was conducted retrospectively through the review of medical records of epilepsy patients. From a total population of 1,236 medical record data, 303 samples were collected that satisfied the inclusion criteria. The analyzed data included patient characteristics based on gender and age, types of AED therapy, dosage, and usage rules. The study results show that outpatient epilepsy patients were predominantly female (53.14%) and the young adult age group 19-65 years (81.19%). The most commonly used therapy pattern was monotherapy, with Phenytoin 100 mg being the most frequently prescribed drug (28.38%), mainly at a dose of 1 tablet twice daily. Combination therapy was used in some patients with variations of two to four antiepileptic drugs. The conclusion of this study indicates that phenytoin is still the primary choice in the outpatient management of epilepsy at UNS Hospital, and reflects its role as a first-line drug effective in controlling various types of seizures. Predominated by females (53.14%) and the young adult age group aged 19-65 years (81.19%).
Tingkat Kepuasan Pasien Terhadap Penerapan Aplikasi Tracking Berbasis Digital Antrian Obat Rawat Jalan Di RSUD Dr. Gondo Suwarno Kabupaten Semarang Arrum Rodhiyana; Avianti Eka Dewi Aditya Purwaningsih; Amalia Nurul Ulum
Jurnal Ners Vol. 10 No. 3 (2026): JULI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i3.59998

Abstract

Pelayanan kefarmasian rawat jalan merupakan indikator penting dalam menilai mutu layanan rumah sakit, terutama terkait transparansi informasi antrian obat. Sistem tracking manual sering menimbulkan ketidakjelasan informasi yang berdampak pada rendahnya kepuasan pasien. Penelitian ini bertujuan untuk menganalisis perbedaan tingkat kepuasan pasien sebelum dan sesudah penerapan sistem tracking berbasis digital sebagai bagian dari transformasi digital pelayanan kefarmasian di RSUD dr. Gondo Suwarno Kabupaten Semarang. Penelitian ini menggunakan pendekatan kuantitatif dengan desain before–after pada 372 responden. Data dikumpulkan menggunakan kuesioner skala Likert yang telah teruji validitas dan reliabilitasnya. Analisis dilakukan dengan uji Paired Sample t-test dan korelasi Spearman pada tingkat signifikansi 0,05. Hasil menunjukkan bahwa kepuasan pasien meningkat dari 11,3% sebelum implementasi menjadi 81,2% setelah penerapan sistem digital. Uji statistik menunjukkan perbedaan yang signifikan (p < 0,001) serta hubungan positif dan signifikan antara penerapan sistem digital dan kepuasan pasien (r = 0,164; p = 0,001). Penerapan sistem tracking berbasis digital terbukti meningkatkan transparansi layanan serta berkontribusi terhadap peningkatan mutu pelayanan dan kepuasan pasien rawat jalan.
Analisis Tingkat Kepuasan Pasien Rawat Jalan Pada Pelayanan Kefarmasian Di Rumah Sakit Universitas Sebelas Maret Periode Bulan Oktober Tahun 2023 Dzithauly Maulidiva Abadi; Endang Sri Rejeki; Avianti Eka Dewi Aditya Purwaningsih
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p66-71

Abstract

Pharmaceutical health services need to be considered service standards, one of which is about patient satisfaction with pharmaceutical services in hospitals. Patient satisfaction is the patient's assessment of the service delivery received. The purpose of the study was to determine the level of patient satisfaction with pharmaceutical services and determine the relationship between the level of satisfaction with the dimensions of patient satisfaction. This type of research is descriptive non-experimental with cross sectional method. The study used 100 respondents. Data collection using accidental sampling method. Data analysis used univariate tests to obtain frequency distribution of patient satisfaction levels. Simple linear regression bivariate analysis to determine the relationship between patient satisfaction level and satisfaction dimension. The patient satisfaction level of the pharmaceutical installation of Sebelas Maret University Hospital obtained reliability results of 75.25%, responsiveness 70.43%, emphty 69.16%, assurance 77%, tangible 74.87%. The relationship between service quality and the highest level of satisfaction obtained the responsiveness dimension of 0.742
EVALUASI KEPATUHAN PENGGUNAAN FORMULARIUM RUMAH SAKIT DAN FORMULARIUM NASIONAL DI RUMAH SAKIT X TAHUN 2024 anggita rosi indayani; Avianti Eka Dewi Aditya Purwaningsih; Francisca Leviana
Jurnal Farmasi Indonesia Vol 22 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v22i2.2673

Abstract

Pelayanan kefarmasian bertujuan untuk meningkatkan kualitas hidup pasien dengan menyediakan layanan yang langsung dan bertanggung jawab dalam penggunaan obat. Salah satu standar minimal Rumah Sakit dalam bidang kefarmasian adalah mencapai kesesuaian penulisan resep dengan formularium sebesar 100%. Jenis penelitian yang digunakan adalah non-eksperimental, dengan metode deskriptif. Pengumpulan data dilaksanakan dengan pendekatan retrospektif, yang melibatkan observasi serta evaluasi terhadap data penjulan obat pasien baik yang dirawat jalan maupun yang dirawat inap di RS X pada bulan Januari – Desember 2024 melalui system informasi management Rumah Sakit (SIMRS). Data yang diperoleh dari penelitian ini mengambarkan tingkat kepatuhan penggunaan formularium di Rumah Sakit X selama bulan januari – desember 2024 masih belum mencapai 100%, yaitu kepatuhan penggunaan Formularium Rumah Sakit rata-rata sebesar 94,07% dan kepatuhan terhadap Formularium Nasional sebesar 80,01%.
EVALUASI KETEPATAN PEMBERIAN ALTEPLASE DAN OUTCOME KLINIS PADA PASIEN STROKE ISKEMIK AKUT DENGAN TERAPI TROMBOLISIS DI RUMAH SAKIT X TAHUN 2024 DAVINA ADIRA NATALIA; Avianti Eka Dewi Aditya Purwaningsih; Francisca Tri Wituningtyas
Jurnal Farmasi Indonesia Vol 22 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v22i2.2674

Abstract

This study aimed to evaluate the timeliness of alteplase administration and clinical outcomes in acute ischaemic stroke patients at Hospital X in 2024. Using a retrospective analytic observational design, data were collected from patients' medical records with a focus on the timeliness of alteplase administration (<4.5 hours) and its impact on clinical outcomes. All patients (100%) received alteplase in a timely manner, according to AHA guidelines, with none receiving therapy after 4.5 hours. The results showed that the timeliness of alteplase administration had a significant effect on clinical outcome, with 90.9% of patients achieving a positive outcome. alteplase administration within the appropriate time window is critical for the clinical recovery of acute ischaemic stroke patients.
ANALISIS PERENCANAAN OBAT ANTIBIOTIK DENGAN METODE ABC DI INSTALASI FARMASI RUMAH SAKIT X TAHUN 2024 Feny Febrianti; Avianti Eka Dewi Aditya Purwaningsih; Fransisca Tri Wituningtyas
Jurnal Farmasi Indonesia Vol 22 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v22i2.2737

Abstract

Efficient drug procurement planning is crucial in hospital pharmacy logistics, especially for antibiotics, which consume a significant portion of the budget. This study analyzes antibiotic procurement planning at the Pharmacy Department of Hospital X in 2024 using the ABC analysis method. Out of 132 antibiotic items, 9 items (6.8%) in category A accounted for 69.32% of total costs, 22 items (16.7%) in category B for 20.41%, and 101 items (76.5%) in category C for only 10.27%. These findings support the Pareto principle and highlight the need to prioritize control over category A items. The study recommends a cost-based procurement system, integration of early warning systems, and adjustment of reorder points to achieve more rational and cost-effective antibiotic inventory management.
Co-Authors Adhi Wardhana Amrullah Adhi Wardhana Amrullah Agnes Prawistya Sari Amalia Nurul Ulum Amalia Nurul Ulum Amrullah, Adhi Wardhana anggita rosi indayani Arrum Rodhiyana As Syifa Roidhotul Jannah Putri Widi Atiek Murharyati Chandra, Sherley Widya DAVINA ADIRA NATALIA Djoko Wahyono Djoko Wahyono Dzithauly Maulidiva Abadi E. Aprilia L. Tobing Eersta Zusvita Widyastuti Effendy, Aura Nurul Alfiah Endang Sri Rejeki Feny Febrianti Fita Rahmawati Fita Rahmawati Francisca Leviana Francisca Tri Wituningtyas Fransisca Tri Wituningtyas Harsono, Samuel Budi Marlina, Dian Maya Nur Ayu Fatdhillillah Novita Sari Nur Anggreini Dwi Sasangka Rahardjoputro, Rolando Rolando Rahardjoputro Sari, Agnes Prawistya Untsa, Farrohatul Widyaningrum, Riana Widyastuti, Eersta Zusvita Zulfia Widiastuti