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Evaluasi Penggunaan Obat Antibiotik Secara Kualitatif dan Kuantitatif Pada Pasien Rawat Inap Tonsilitas RS X Surakarta Purwaningsih, Avianti Eka Dewi Aditya; Effendy, Aura Nurul Alfiah; Widyaningrum, Riana
Generics: Journal of Research in Pharmacy Vol 5, No 2 (2025): Generics : Journal of Research in Pharmacy Volume 5, Edisi 2, 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v5i2.25642

Abstract

Tonsilitis suatu kondisi peradangan pada bagian tonsil palatinda, termasuk salah satu bagian dari cincin waldeyer yang sering disebabkan oleh virus Epstein Barr. Infeksi ini ditularkan melalui cairan tubuh (air liur) dan udara (air borne, droplet). Pemberian antibiotik pada nyeri tenggorokan khususnya pada tonsilitis yang tidak sesuai dengan algoritma terapi dapat menimbulkan resistensi bakteri. Penelitian ini bertujuan untuk mengevaluasi penggunaan antibiotik di Rumah Sakit X Surakarta. Penelitian observasional dengan metode probability sampling untuk analisa deskriptif. Penggunaan antibiotika dianalisa kuantitatif (metode ATC/DDD) dan kualitatif (metode Gyssens). Data yang didapatkan dianalisa secara deskriptif kemudian ditampilkan dalam bentuk tabel. Hasil penelitian, penggunaan antibiotik selama bulan Januari – Desember 2023 memiliki nilai DDD sebesar 39,182 DDD. Penggunaan antibiotik paling besar yaitu Cefuroxime dengan nilai DDD/100 hari sebesar 19,705 DDD. Hasil evaluasi secara kualitatif ditemukan ketidakcocokan pada kategori IVA, IVC, IVD, dan IIIB sebanyak 33 kasus (53,2%).
KAJIAN PENGGUNAAN ANTIBIOTIK PROFILAKSIS PADA PASIEN BEDAH CESAR DI RSUD IBU FATMAWATI SOEKARNO KOTA SURAKARTA TAHUN 2020 Purwaningsih, Avianti Eka Dewi Aditya; Chandra, Sherley Widya; Harsono, Samuel Budi
Jurnal Pharmacopoeia Vol 2 No 1 (2023): Maret 2023
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jp.v2i1.352

Abstract

Pemberian antibiotik profilaksis disarankan untuk persalinan sectio caesarea karena terbukti efektif menurunkan angka infeksi luka operasi. Tujuan penelitian ini untuk mengkaji ketepatan dalam pemberian antibiotik profilaksis di RSUD Ibu Fatmawati Soekarno tahun 2020 menggunakan metode Gyssens. Jenis penelitian ini termasuk deskriptif non eksperimental. Pengambilan data secara retrospektif dengan melihat data rekam medik pasien bedah cesar di RSUD Ibu Fatmawati Soekarno tahun 2020. Analisis data dilakukan secara deskriptif yang digunakan untuk mengkaji berupa karakteristik pasien, pola penggunaan antibiotik profilaksis, serta kesesuaian dengan pedoman yang dibandingkan dengan bagan alur Gyssens. Hasil penelitian pada pasien bedah cesar di RSUD Ibu Fatmawati Soekarno tahun 2020 menunjukkan antibiotik yang paling sering digunakan adalah sefuroksim (92,61%), seftriakson (2,96%), ampicillin+sulbaktam (2,46%), ampicillin (1,48%), sefadroksil (0,49%). Kajian penggunaan antibiotik profilaksis berdasarkan Gyssens diperoleh kategori 0 (74,06%), kategori VI (23,68%), dan kategori IVA (2,26%). Rute pemberian intravena sudah sesuai dengan pedoman (100%). Dosis, interval, durasi antibiotik sudah sesuai yaitu penggunaan dosis 1-2g dengan frekuensi 2x sehari, durasi 1-2 hari (100%). Waktu pemberian ≤30 menit (100%).
Evaluation of Inpatient Antibiotic Use at Hospital X, Semarang Regency, in 2023 Using Quantitative Methods Ivana; Avianti Eka Dewi Aditya Purwaningsih; Fadhila Shaumi Chunaesiana
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/q734wz44

Abstract

Background: Antibiotic resistance is a critical global health problem resulting from the inappropriate use of antibiotics. Understanding the pattern of antibiotic utilization is necessary to support rational prescribing and reduce resistance.Objective: This study aimed to evaluate the pattern of antibiotic use among inpatients at Hospital X in Semarang Regency in 2023. Methods: A retrospective study was conducted among inpatients aged 19–59 years who received antibiotic therapy between January and December 2023. Data were analyzed using the Anatomical Therapeutic Chemical/Defined Daily Dose method and Drug Utilization 90% to assess consumption patterns. Results: A total of 1,402 patients were included, with most patients being female and within the 49–59 age group. The majority of hospital stays lasted 1–5 days. Ceftriaxone injection is the most frequently used antibiotic and records the highest defined daily dose, followed by levofloxacin and ampicillin sulbactam. Conclusion: The study shows that ceftriaxone injection dominates antibiotic utilization. Regular evaluation using standardized methods is essential to ensure appropriate use and prevent resistance. Antibiotic procurement policies should be guided by actual consumption data to improve efficiency in drug management.
Antibiotic Use in Inpatients with Diarrhea in Children: A Quantitative Evaluation at Hospital X, Semarang Regency, 2023 Widiastuti, Zulfia; Purwaningsih, Avianti Eka Dewi Aditya; Ulum, Amalia Nurul
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/s8qfqn40

Abstract

Background : Infection remain one of the leading causes of morbidity in tropical regions such as Indonesia, with Escherichia coli being one of the most freequently identified pathogens. The high incidence of Escherichia coli-related infections has led to increased antibiotics use, considering that this commensal gut bactericum can cause both asymptomatic infections and symtomatic diarrhe, either bloody or non-bloody. Objective : This study aimed to evaluate use in pediatric patiens with diarrea at Hospital X, Semarang Regency, in 2023. Methods: This was a retrospective study uutilizing medical records of 323 pediatric patiens who met the inclusion and exclusion criteria. Data analysis was performed using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) methodology. Result:The analysis revealed that Ceftriaxone injection was the most frequently used antibiotic (61.95%), followed by Ampicillin, Amikacin, Gentamicin, and Cefotaxime. Ceftriaxone was often prefered due to its efficacy against both gram-positive and gram-negative bacteria comonly associated with pediatric diarrhea, as well as the advantage of accurate dosing trough injectable formulations. Most diarrhea cases occurred in boys (62.54%) and in children under five years of age (65.63%). Conclusion:Injectable formulations were chosen to reduce the risk of vomiting and to facilitate precise and effective dosing. Evaluation using the ATX/DDD method highlighted the need for more rational antibiotic management to prevent bacterial resistance in the future. Optimizing antibiotic stewardship is crucial to ensure targeted in the future. Optimizing antibiotic stewardship is crucial to ensure targeted, effective use and to preserve therapeutic efficacy in the long term. 
Analisis Tingkat Kepuasan Pasien Rawat Jalan Pada Pelayanan Kefarmasian Di Rumah Sakit Universitas Sebelas Maret Periode Bulan Oktober Tahun 2023 Abadi, Dzithauly Maulidiva; Rejeki, Endang Sri; Purwaningsih, Avianti Eka Dewi Aditya
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p66-71

Abstract

Pharmaceutical health services need to be considered service standards, one of which is about patient satisfaction with pharmaceutical services in hospitals. Patient satisfaction is the patient's assessment of the service delivery received. The purpose of the study was to determine the level of patient satisfaction with pharmaceutical services and determine the relationship between the level of satisfaction with the dimensions of patient satisfaction. This type of research is descriptive non-experimental with cross sectional method. The study used 100 respondents. Data collection using accidental sampling method. Data analysis used univariate tests to obtain frequency distribution of patient satisfaction levels. Simple linear regression bivariate analysis to determine the relationship between patient satisfaction level and satisfaction dimension. The patient satisfaction level of the pharmaceutical installation of Sebelas Maret University Hospital obtained reliability results of 75.25%, responsiveness 70.43%, emphty 69.16%, assurance 77%, tangible 74.87%. The relationship between service quality and the highest level of satisfaction obtained the responsiveness dimension of 0.742