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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Riset Industri Hasil Hutan Jurnal Kajian Ilmiah Kesehatan Dan Teknologi (JKIKT) Borneo Journal Of Pharmascientech Sasambo Journal of Pharmacy J-ABDIPAMAS (Jurnal Pengabdian Kepada Masyarakat) Jurnal Pengabdian Masyarakat Panacea Borneo Journal of Pharmacy Pharmacon: Jurnal Farmasi Indonesia Journal of Pharmascience
Mia Fitriana
Program Studi Farmasi FMIPA Universitas Lambung Mangkurat Banjarbaru
Agriculture, Biological Sciences & Forestry Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Potensi Antiinflamasi Ekstrak dan Fraksi n-Heksana Daun Galam (Melaleuca cajuputi) Asal Kalimantan Selatan Sutomo, Sutomo; Arnida, Arnida; Amalina, Amalina; Fadlilaturrahmah, Fadlilaturrahmah; Fitriana, Mia
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 2 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i2.754

Abstract

South Kalimantan has a unique topography that includes tidal areas and swamps, and peatlands. One of the natural resources that grows well in this area is the galam tree (Melaleuca cajuputi). Traditionally, this plant has been used to treat various inflammatory conditions, such as intestinal inflammation, sore throat, itchy skin, and rheumatism. M. cajuputi contains flavonoid compounds that are believed to have anti-inflammatory properties. This study aimed to determine the anti-inflammatory activity of ethanol extracts and n-hexane fractions of M. cajuputi leaves from South Kalimantan using a protein denaturation inhibition method with IC50 values as the parameter. Sodium diclofenac was used as the positive control in this study. The results of the anti-inflammatory activity test showed that the IC50 values for sodium diclofenac, ethanol extract, and n-hexane fraction of M. cajuputi leaves were 14.948; 51.577; and 61.700 ppm, respectively. Statistical analysis revealed a significant difference between the IC50 value of sodium diclofenac and those of the ethanol extract and n-hexane fraction. Based on the study conducted, it can be concluded that the ethanol extract and n-hexane fraction have anti-inflammatory activity, although their potency is lower than that of sodium diclofenac
Formulasi dan Evaluasi Masker Wajah Peel-Off Mengandung Kuersetin dengan Variasi Konsentrasi Gelatin dan Gliserin Rahmawanty, Dina; Yulianti, Nita; Fitriana, Mia
Media Farmasi: Jurnal Ilmu Farmasi Vol. 12 No. 1: Maret 2015
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v12i1.3019

Abstract

Kuersetin dapat menjadi salah satu alternatif bahan aktif anti jerawat danpencegah penuaan dini karena dapat menghambat pertumbuhan bakteri penyebab jerawat Staphylococcus epidermidis dan Propionibacterium acnes dan memiliki aktivitas antioksidan pada konsentrasi 0,05%. Masker wajah peel off adalah salah satu jenis masker wajah yang memiliki keunggulan dalam penggunaannya yaitu mudah diangkat atau dilepaskan seperti membran elastis. Penelitian ini bertujuan untuk menentukan pengaruh penambahan variasi konsentrasi gelatin dan gliserin terhadap sifat fisika dan kimia masker wajah peel off kuersetin. Variasi konsentrasi gelatin yang digunakan adalah10%, 15% dan 20%, variasi konsentrasi gliserin yang digunakan adalah 2%, 6% dan 12%. Evaluasi sediaan masker wajahpeel off kuersetin meliputi karakteristik organoleptis (warna, konsistensi, bau), waktu mengering, viskositas, pH, homogenitas, daya sebar dan daya lekat. Data  hasil evaluasi sediaan masker wajah peel off  kuersetin dianalisis dengan program Design Expert 8.0.7. dengan desain faktorial dan Kruskal Wallis. Hasil menunjukkan bahwa variasi konsentrasi gelatin dan gliserin secara signifikan mempengaruhi organoleptis, waktu mengering, homogenitas, viskositas, daya lekat dan daya sebar sediaan (p<0,05), variasi konsentrasi gelatin dan gliserin secara signifikan tidak mempengaruhi pH dari sediaan (p>0,05).
Formulation and Evaluation of Nanoemulsion Kelakai (Stenochlaena palustris) Herbs with Composition of Smix (Tween 80 and Glycerin) and Pine Oil Helsawati, Helsawati; Ratnapuri, Prima Happy; Fitriana, Mia
Borneo Journal of Pharmacy Vol. 6 No. 4 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i4.3817

Abstract

Kelakai (Stenochlaena palustris) herb is a typical South Kalimantan plant containing bioactive substances that can serve as antioxidants. It can be formulated into nanoemulsions to increase bioavailability in the skin. This study aimed to determine the ratio of pine oil and Smix (tween 80 and glycerin) as the optimal base for nanoemulsion based on the highest percent transmittance and to determine the physical characteristics of the S. palustris herb extract nanoemulsion with variations in the amount of extract. Bases of nanoemulsion formula were optimized using a ternary phase diagram and D-Optimal Mixture Design. Nanoemulsion contained three extract concentrations: 0.1; 0.25; and 0.5%, respectively, and nanoemulsion was tested for physical characteristics. The results of this study were a light yellow to light brown, clear, and transparent, with a characteristic weak-strong odor, forming an O/W nanoemulsion. Increasing the concentration of the extract significantly increased the viscosity and decreased the pH and percent transmittance. This study concluded that variations in extract concentration affected the percent transmittance, organoleptic, pH, viscosity, and the optimal ratio of nanoemulsion components was 1% pine oil, 9% Smix, and 90% water.
Pemberdayaan Pengrajin Lulur Timung dalam Akselerasi Kualitas Home SPA Khas Suku Banjar Fitriana, Mia; Anwar, Khoerul; Fadlilaturrahmah, Fadlilaturrahmah
J-ABDIPAMAS (Jurnal Pengabdian Kepada Masyarakat) Vol. 8 No. 1 (2024): April 2024
Publisher : IKIP PGRI Bojonegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30734/j-abdipamas.v8i1.2297

Abstract

The traditions of balulur and batimung are still carried out today. One of the production places for cucumber scrub in the city of Banjarmasin is Ipah Zein MSME. The cucumber scrub product by Ipah Zein MSME is a concoction that has been passed down from generation to generation and has been producing cucumber scrub for three generations. During these three generations, the making of scrub and timung was still done traditionally. The quality of this product needs to be improved so that it can still be marketed. The implementation of this service aims to improve the quality dimensions of Ipah Zein MSME timung scrub products, both product quality and packaging quality. Activities will be carried out from April to December 2021 at the Ipah Zein timung scrub production house. The method used begins with preparation, then implementation of activities and evaluation of activities. Activities that have been carried out include modernizing equipment in the production process, assisting production according to Good Cosmetic Manufacturing Practices, mechanizing packaging equipment and improving traditional cosmetic packaging designs. The results show that the service activities have been carried out well, where there has been an increase in the quality of Ipah Zein MSME timung scrub products, both product quality and packaging quality. Service partners have been equipped with knowledge about Good Cosmetic Manufacturing Practices, given equipment that supports this and the product has a more attractive design and is more acceptable to the marketKeywords: scrubs, timung, quality Tradisi balulur dan batimung masih dilakukan sampai saat ini. Salah satu tempat produksi lulur timung di kota Banjarmasin adalah UMKM Ipah Zein. Produk lulur timung oleh UMKM Ipah Zein adalah ramuan warisan turun menurun dan sudah memproduksi lulur timung selama tiga generasi. Selama tiga generasi tersebut, pembuatan lulur dan timung masih dikerjakan secara tradisional. Produk ini perlu ditingkatkan kualitasnya agar tetap dapat dipasarkan. Pelaksanaan pengabdian ini bertujuan untuk meningkatkan dimensi kualitas produk lulur timung UMKM Ipah Zein, baik mutu produk maupun mutu kemasan. Kegiatan dilakukan pada bulan April sampai Desember tahun 2021 di rumah produksi lulur timung Ipah Zein. Metode yang dilakukan diawali dengan persiapan kemudian pelaksanaan kegiatan dan evaluasi kegiatan. Kegiatan yang telah terlaksana meliputi modernisasi peralatan pada proses produksi, pendampingan produksi sesuai Cara Pembuatan Kosmetik yang Baik (CPKB), mekanisasi alat pengemas dan peningkatan desain kemasan kosmetika tradisional. Hasil menunjukkan bahwa kegiatan pengabdian telah terlaksana dengan baik dimana terjadi peningkatan kualitas produk lulur timung UMKM Ipah Zein, baik mutu produk maupun mutu kemasan. Mitra pengabdian telah dibekali pengetahuan mengenai CPKB, diberikan peralatan yang menunjang hal tersebut dan produk telah memiliki desain yang lebih menarik dan lebih dapat diterima pasar.Kata Kunci: lulur, timung, kualitas 
Aktivitas Antibakteri Ekstrak Metanol Bunga Teratai (Nymphaea pubescens Willd) Amalia Khairunnisa; Nashrul Wathan; Mia Fitriana; Fadlilaturrahmah Fadlilaturrahmah; Nisriyati Fiddina
Journal of Pharmascience Vol. 7 No. 2 (2020): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.8486

Abstract

Nymphaea pubescens Willd telah diketahui mempunyai efek antibakteri, terutama pada biji dan daunnya. Tetapi sampai saat ini bagian bunga dari tanaman tersebut belum dilakukan pengujian aktivitas antibakteri. Tujuan dari penelitian ini untuk melakukan skrining fitokimia, uji aktivitas antibakteri dan penentuan konsentrasi hambat minimum (KHM) dari ekstrak metanol bunga N. pubescens terhadap S. aureus dan E. coli. Proses ekstraksi bunga N. pubescens dimaserasi menggunakan pelarut metanol dengan perbandingan 1: 4 b/v. Metode pengujian yang digunakan ada dua yaitu metode difusi untuk pengujian aktivitas antibakteri dan metode dilusi untuk pengukuran konsentrasi hambat minimum (KHM). Hasil skrining fitokimia didapatkan bahwa ekstrak metanol bunga N. pubescens mengandung senyawa golongan fenolik, saponin dan flavonoid. Hasil pengujian aktivitas antibakteri menunjukkan bahwa ekstrak metanol bunga N.pubescens mampu menghambat S. aureus (diameter hambat 10 ± 0,29 mm) dan E.coli (diameter hambat 10,2 ± 0,50 mm). Konsentrasi hambat minimum dari ekstrak metanol bunga N. pubescens terhadap S.aureus sebesar 12,5% dan terhadap E.coli sebesar 25%. Dapat disimpulkan bahwa ekstrak metanol bunga N. pubescens memiliki aktivitas sebagai antibakteri. Nymphaea pubescens Willd has known to have antibacterial effects, especially on the seeds and leaves. However, until now the flower of the plant has not been tested for antibacterial activity. The purpose of this study was to perform phytochemical screening, antibacterial activity test and determine the minimum inhibitory concentration (MIC) of the methanol extract of N. pubescens flowers against S. aureus and E. coli. The process of extracting N. pubescens flowers is macerated using methanol as a solvent with a ratio of 1: 4 w / v. There are two test methods used, namely the diffusion method for testing antibacterial activity and the dilution method for measuring the minimum inhibitory concentration (MIC). The results of phytochemical screening showed that the methanol extract of N. pubescens flowers contained phenolic compounds, saponins, and flavonoids. The results of the antibacterial activity test showed that the methanol extract of N.pubescens flowers was able to inhibit S. aureus (inhibition diameter 10 ± 0.29 mm) and E. coli (inhibitory diameter 10.2 ± 0.50 mm). The minimum inhibitory concentration of the methanol extract of N. pubescens flowers against S.aureus was 12.5% and against E. coli was 25%. It can be concluded that the methanol extract of N. pubescens flowers has antibacterial activityKeywords: Nymphaea pubescens, lotus flower, methanol extract, antibacterial
Co-Authors Amalia Khairunnisa Amalina Amalina, Amalina Anna Khumaira Sari Arnida Arnida Beny Rahmanto Cahyani, Syifa Nur Difa Intannia Dina Rahmawanty Dina Rahmawanty Fadlilaturrahmah Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Helsawati, Helsawati Isnaini, Nazhifah Izma, Hayatun Khoerul Anwar Khoerul Anwar Khoirunnisa Muslimawati Kurniasari, Winda Tri Maharani, Ni Ayu Muhammad Ikhwan Rizki Nahdiya, Nahdiya Nashrul Wathan Nisriyati Fiddina Nita Yulianti Nita Yulianti, Nita Noridafi, Noridafi Normaidah, Normaidah Rahmatullah, Satrio Wibowo Rahmawanty, Dina Ratnapuri, Prima Happy Rusda, Salsabila Azzahra Safarina, Nor Rezky Sandi, Dita Ayulia Dwi Sarwo, Laura Siswadi Siswadi Susy Andriani Sutomo Sutomo Wawan Halwany Yulianti, Nita Yuni Kartika Yusrinie Wasiaturrahmah Zainah, Alya