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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
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SEDIAAN KRIM EKSTRAK AIR BUAH AREN (Arenga pinnata) SEBAGAI ANTIOKSIDAN Riny Erfiah Rinda; A. Mumtihanah Mursyid; A. Hasrawati
As-Syifaa Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (356.606 KB) | DOI: 10.33096/jifa.v11i1.449

Abstract

Palm fruit (Arenga pinnata) contains galactomannan which has the potential as an antioxidant activity with an IC50 value of 20,45 ppm. This study aims to produce cream dosage forms with antioxidant activity using the scaverry DPPH radical scavenger method from arenga pinnata water extract. Palm fruit water extract is formulated in cream form with variations in the concentration of stearic acid and triethanolamine emulgators in F1 (6:4), F2 (7:3), and F3 (8:2). Evaluation of physical stability includes organoleptic testing, homogeneity, pH, emulsion type, viscosity and type of flow carried out before and after forced conditions. In the statistical analysis of viscosity, the results of each formula showed no significant changes both before and after the conditions were forced. The results of the study obtained formula 2 and formula 3 has optimal stability. The stable formula was then tested for antioxidants using the DPPH (1,1-Diphenyl-2-Picrylhydrazyl) radical scavenger method. Formula 2 and formula 3 each yield a DPPH radical inhibition percentage of 65% and 48.04%. 
FORMULASI MASKER GEL (PEEL OFF MASK) SARI BUAH TOMAT APEL (Licopersicum esculentum Mill) Faradiba Faradiba; Ermina Pakki; Aulia Wati; Amelia Jabbar
As-Syifaa Jurnal Farmasi Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.094 KB) | DOI: 10.33096/jifa.v4i2.77

Abstract

In this study, three formulas gel with varying polyvinyl alcohol   9%, 9,5%, and 10%. Then do the evaluation of physical stability by organoleptic examination of the test parameters, measurements of viscosity, yield value determination  and pH determination before and after accelarated storage. The results obtained in the second organoleptic examination of the gel formula does not change the color, smeel and consistency before and after accelerated storage. In the viscosity measurements obtained results in the formula A  were not significantly different before and after accelerated storage. Results of statistical analysis of the value of yield showed that the formula A were not significantly different before and accelerated storage. In rheogram formula A have the curves that coincide, formula B and C have seen that the curve is not too close together  before and after accelerated storage. In pH determination, formula A have neutral pH  of 6,9,  formula B and C have pH of 6,8, so it can be concluted that two stocks is stable, but their stability is the most optimal formula A (concentration 9 %). Key words : Mask Gel, Apple Tomato
AKTIVITAS ANTIOKSIDAN FRAKSI RIMPANG KENCUR (KAEMPFERIA RHIZOMA) DENGAN MENGGUNAKAN METODE PEREDAMAN 1,1 DIPHENYL-2-PICRYLHYDRAZIL (DPPH) Muhafidzah, Zahrah; Dali, Seniwati; Syarif, Rezky Amriati
Jurnal Ilmiah As-Syifaa Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (684.818 KB)

Abstract

Kaempferia is one of the most widely used plants in society is a traditional at the medicine. Empirically Kaempferia rhizome has a special quality as a wound healer, good for digestion, antibacterial, and as an antioksidant. Based on research been conducted that Kaempferia extract has antioxidant activity. This research aimed to test antioxidant activity base on IC50 value on kaempferia rhizome fraction by the reduction method 1,1 diphenil-2-phicrylhydrazil (DPPH). The extract obtained was fractionated using a vacuum liquid chromatography method, then performed free radical reduction meansurements using UV-VIS spectrophotometry. A positive fraction of antioxidants activity is the n-hexane fraction : ethyl acetate (7:3 and 8:2). The n-hexane fraction 8:2 showed higher antioxidant activity with IC50  731.832 µg/mL. The n-hexane fraction: ethyl acetate 7:3 with IC50  829.737 µg/mL
STUDI KOMPARSI TERHADAP LAJU DISOLUSI TABLET PARASETAMOL DENGAN PENAMBAHAN POLISORBAT 80 Najib, Ahmad
Jurnal Ilmiah As-Syifaa Vol 2, No 1 (2010): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

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Abstract

A study of the dissolution rate of paracetamol tablets using polysorbate 80 as wetting agent had been investigated. The aim of this investigation  is to determine  concentration of polysorbate 80 should be added to the formula to produced the tablet with the fastest dissolution rate.   The paracetamol tablets were prepared by wet granulation methods using polysorbate 80 with various concentration,   1%, 3%, 5%, 7% and 9% respectively. The tablet without polysorbate 80 was also prepared for comparison. The tablets had been evaluated with uniform size, uniform weight, hardness, disintegration time and the dissolution test.               The dissolution test of  tablet in phosphate buffer pH 5.8  using the stirring paddle  with rotation speed at 50 rpm at the temperature 37 ± 0.5°C. The release of paracetamol every time appointed well measured by UV spectrophotometer at wave length 242 nm and the concetration determinated with standard curve.            The evaluation of tablets showed that no one formula  suitable with requires, the hardness test only  formula I suitable with requires and the disintegration time all of the tablet suitable with requires. The result of statistical with complete random form method show the added of polysorbate 80 in the parasetamol tablets formula increase dissolution of paracetamol. The analysis efficiency dissolution using Duncan?s method on data?s showed that the concentration 3% of polysorbate 80 (formula III) give significant effect in increasing the dissolution rate of tablets ( a = 0.05 ).Key word : Polisorbat 80, Dissolition, Paracetamol
ALTERNATIF SPLINTING PADA KEGOYANGAN GIGI AKIBAT PENYAKIT PERIODONTAL Astuti, Lilies Anggarwati
Jurnal Ilmiah As-Syifaa Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (203.591 KB)

Abstract

Periodontal disease is a disease of inflammation of the tissues around the tooth that originated from inflammatory gingival and continues to the periodontal structures other periodontal ligament and cementum, and the alveolar bone. Loosening of the teeth is one of the symptoms of periodontal disease characterized by loss of bonding as well as vertical bone damage. Loosening can be caused by damage to the bone that supports the teeth, trauma from occlusion, and the presence of inflammation of the gingiva to the expansion of the network of supporters who are more patologik and processes in the jaw. Purpose: one of the ways to control and stabilize the loosening of the teeth is splinting. Splinting is indicated on the State loosening teeth degree 3 with severe bone damage. Literature review: Periodontal splint is a tool that can be used for stabilization or loosening of teeth that immobilisasi experience. Splint consists of temporary and permanent splint splint. Indication temporary splint is for stabilization of teeth rocking before and during therapy with the goal to reduce the peridontal trauma at the time of care and speed up the healing process, such as the ligature wire splint. Discharging permanent splint is part of this phase of the restoration or reconstruction phases of periodontal care. Permanent Splint is extremely limited usage. Used when actually used to increase the stability of pressure oklusal. Summary: the selection of the alternatives of periodontal splint adapted on certain conditions, such as economic status and health status of the patient.
FORMULASI MINYAK-MINYAK MENGUAP MENJADI SEDIAAN BALSEM COUNTERIRRITANT Zulkarnain, Iskandar; Aminullah, Aminullah
Jurnal Ilmiah As-Syifaa Vol 4, No 1 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

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Abstract

Volatile oils have efficacy as a counterirritant. Formulation of valitel oils into counterirritant ointment preparations. The research objective of volatile oils formulations into stable dosage balm. The study conducted with qualitative examination of all the materials used. Test parameters measured are fatty oils, solubility in alcohol, the determination of optical rotation, refractive index and specific gravity. Formulation and manufacture of balm performed using the hydrocarbon base cera alba and Vaseline alba. Balm that has to be evaluated by storing at extreme temperature cycles. Parameters measured werw organoleptis examination, measurementof viscosity and yieldvalue determination, as well as examinationof heavy metal and microbial contamination. The result obtained throughout the testing on a qualitative examination of the raw material requirement. The test result organoleptic is white, odoless typical, with a appropriate consistency. Viscosity of preparation did notchange significantly. Preparation do not contain heavy metal and harmful microbes. Key Word : volatile oils, balm, stability
PROFIL PERESEPAN OBAT PADA PASIEN RAWAT JALAN JAMKESDA DARI POLI KARDIOVASKULAR DI APOTEK RUMAH SAKIT LABUANG BAJI MAKASSAR PERIODE JANUARI – JUNI 2014 Olii, Audi Triani; Nurlina, Nurlina; Niswah, Hilyatun
Jurnal Ilmiah As-Syifaa Vol 6, No 2 (2014): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

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Abstract

Study of Drugs Prescribing Profile In Outpatient Jamkesda of Poly Cardiovaskular In Labuang Baji Hospital Makassar period January ? June 2014 has done. The aim of this study is to obtain the secondary data and than  analyzing themby administration screening, pharmaceutical screening and clinical screening. This study was descriptive type with retrospective data which taken from secondary data on Outpatient Jamkesda of Poly Cardiovaskular In Labuang Baji Hospital Makassar period January ? June 2014. Based on the results of this study, concluded that from 5617 of prescription sheets of Jamksda outpatient were included in the study period, 508 sheets recipe comes from Cardiovascular Poly (9%) which 52,4% from that recipe is male patients,  32,1% are 51-60 years, 89,2% without doctor?s initials, 23,2% of  prescription contain 5 different drugs, 74,8% of  prescription contain  diuretics as the first choice of therapy, and there is a 1133 cases of drug interaction cases. Key words : Prescribing Profile, Cardiovascular, Screening Recipe.
POLA PENGOBATAN TUBERKULOSIS PARU DI BALAI BESAR KESEHATAN PARU MASYARAKAT MAKASSAR PERIODE JANUARI – JUNI 2011 Hendra Herman; Bayu Putra; Citra Dana
As-Syifaa Jurnal Farmasi Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.552 KB) | DOI: 10.33096/jifa.v5i1.68

Abstract

The research was about Tuberculosis Drugs Using System in the  Balai Besar Kesehatan Paru Masyarakat Makassar (BBKPM) Period January 2011 – June 2011. The aim of this research was to describe about using system so obtained TBC drugs which used in the Tuberculosis Drugs Using-System in the  Balai Besar Kesehatan Paru Masyarakat Makassar (BBKPM) Period January 2011 – June 2011. The data taking prospectly via all the tuberculosis patient medical record in the Tuberculosis Drugs Using System in the  Balai Besar Kesehatan Paru Masyarakat Makassar (BBKPM) Period January 2011 – June 2011 obtained 30 patients. The result of this research can be concluded that from the regiment side, about 96,7% Tuberculosis patients which treatment in the  Balai Besar Kesehatan Paru Masyarakat Makassar (BBKPM) Period January 2011 – June 2011 were category 1 and the residual was category 3. While the side of combination with the other drug, giving combination dominated about 96,7%. While if the give single drug about 3,3%. The frequency of  the other drug usage was dextromethorphan about 90% and the smaller was pyridoxin about 10%.Key Word : Using System, Tuberculosis Drugs, BBKPM
PENGARUH EFEK EKSTRAK ETANOL DAUN SIRIH ( Piper Betle Linn.) SEBAGAI ANTIOKSIDAN TERHADAP LUKA BAKAR PADA KULIT PUNGGUNG KELINCI (Oryctolagus Cuniculus) Muhammad Asri
As-Syifaa Jurnal Farmasi Vol 9, No 2 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.582 KB) | DOI: 10.33096/jifa.v9i2.302

Abstract

The burn are injuries to the skin where a response to the skin and subcutaneous tissue to the trauma experienced. The burn with partial thickness is a burn that does not damage the epithelial tissue of the skin and only damage some of the epithelial. This research aims to determine the effect of ethanol extract of betel leaf (Piper betle Linn.) As an antioxidant to burns on the skin back of the rabbit's (Oryctolagus Cuniculus). The experimental method was carried out experimentally, divided into 5 groups and treatment for 7 days, P1 negatife control (made wound on the skin back of rabbit and smeared with vaseline flavum), P2 positif control (made wound on rabbit’s skin back and smeared with bioplacenton ointment) P3 (made wound and ethanol extract of betel leaf with 5% concentration), P4 (made wound and ethanol extract of betel leaves with 10% concentration), P5 (made wound and ethanol extract of betel leaves with 15% concentration). The result of the research on the measurement of diameter of burn area on  rabbit's skin back before and after treatment, group I 2.5 cm and 2.4 cm, group II 2.5 cm and 1.9 cm, group III 2.2 cm and 1.9 cm, group IV 2.3 cm and 1.8 cm, and group V 2.3 cm and 1.6 cm. The conclusion of ethanol extract of betel leaf (Piper betle Linn) at concentrations of 5%, 10% and 15% as antioxidants can heal burns on the skin back of the rabbit's .
EFEKTIVITAS PATCH SEDERHANA DARI EKSTRAK DAUN KAYU JAWA (Lannea coromandelica (Houtt.) Merr.) TERHADAP PENYEMBUHAN LUKA SAYAT PADA TIKUS (Rattus norvegicus) Azzahrah, Nur Faatimah; Jamaluddin, Abdul Wahid; Adikurniawan, Yuko Mulyono
Jurnal Ilmiah As-Syifaa Vol 11, No 2 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (428.381 KB) | DOI: 10.33096/jifa.v11i2.531

Abstract

Kayu jawa plants are one type of traditional plant that is often used to treat wounds, both internal and external wounds. This plant has been shown to have anti-microbial, anti-oxidant and anti-inflammatory effects. Flavonoid compounds have anti-inflammatory activity by protecting erythrocyte membranes against membrane damage causing hemolysis because flavonoids can inhibit inflammatory mediators and free radicals. This study aims to determine the effect of the administration of simple patch from Kayu Jawa leaves extract (Lannea coromandelica Houtt. (Merr.)) On wound healing in white rats (Rattus norvegicus) by looking at the extent of the wound closure and changes in wound morphology compared to controls. This study used a laboratory experimental method with 25 rats as test animals divided into 5 treatment groups, namely 3 treatment groups (simple patch from 2.5% kayu jawa leaves extract, simple patch from 5% kayu jawa leaves extract, and simple patch from 10% kayu jawa leaves extract), 1 positive control group (simple patch from povidone iodine) and 1 negative control group (simple patch without kayu jawa leaves extract). The conclusions of the study was the administration of 5% Kayu Jawa leaves extract gave the best effect in accelerating wound healing.

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