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INDONESIA
Indonesian Journal of Medicine
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
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Articles 407 Documents
Effect of Dhikr on Blood Pressure in Pregnant Women with Hypertension Sari, Dian Nirmala; Djamil, Masrifan; Suwandono, Agus
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Hypertension is a 5-10% of complications in pregnancy and is one of the most common causes of death besides bleeding and infection, and also contributes to the mor­bidity and mortality of pregnant women. The purpose of this study was to examine effect of dhikr on blood pressure in pregnant women with hypertension.Subjects and Method: This was an experi­mental study conducted in Banjarnegara dis­trict health center, Central Java, in June 2018. A sample of 30 pregnant women with hyper­tension was selected for this study randomly. The dependent variable was blood pressure. The independent variable was dhikr. Blood pressure was measured by sphygmomano­me­ter. Mean difference between of systolic and diastolic blood pressure in two groups after intervention was tested by t test.Results: After intervention, diastolic blood pressure in the intervention group (Mean= 136.67; SD= 6.17) was lower than in the control group (Mean= 141.33; SD= 5.16), and it was statistically significant (p= 0.006). After inter­vention, diastolic blood pressure in the inter­vention group (Mean= 88.67; SD= 3.52) was lower than in the control group (Mean= 92.00; SD= 4.41), and it was statistically significant (p= 0.025).Conclusion: Dhikr decreases blood pressure in pregnant women with hypertension.Keywords: blood pressure, hypertension, pregnant womenCorrespondence: Dian Nirmala Sari. Applied Midwifery, Gra­duate Program, School of Health Polytechnics, Ministry of Health Semarang. Jl. Tirto Agung, Pedalangan, Banyumanik, Kota Semarang 50268, Central Java, Indonesia. Email: nirma­lasaridian@yahoo.co.idIndonesian Journal of Medicine (2020), 05(01): 87-94https://doi.org/10.26911/theijmed.2020.05.01.12
OBESITY AND DIABETES MELLITUS AS PREDICTORS OF MORTALITY IN PATIENTS WITH STROKE: A META ANALYSIS Karlinda, Karlinda; Tamtomo, Didik Gunawan; Murti, Bhisma
Indonesian Journal of Medicine Vol 4, No 4 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Stroke is the leading cause of death and disability throughout the world. Based on studies in the United States (US), a person experiences a stroke every 40 seconds and every 4 minutes someone dies. The problem of comorbidity or the presence of more than one disease is the risk of stroke. This causes a person with comorbidities to have a higher risk of mortality than stroke patients without comorbidities. This study aims to examine the effect of obesity and diabetes mellitus as predictors of mortality in stroke patients.Subjects and Method: This was a meta-analysis and systematic review. The articles were obtained from Google Scholar, PubMed, Springer Link, Clinical key, and ProQuest databases. The articles have been published from 2010-2019. Keywords to search for articles are as follows: "comorbidity and stroke", "comorbidity and mortality and stroke and cross sectional study", "comorbidity and mortality and stroke and adjusted odd ratio", "comorbidity or stroke", "comorbi­dity or mortality or stroke or cross sectional study ", "comorbidity or mortality or stroke or adjusted odd ratio". The articles studied are full text articles with observational study design. Articles are collected using PRISMA diagram, and analyzed using the Review Manager application 5.3.Results: Obesity (aOR = 1.51; 95% CI = 1.03 to 2.21; p = 0.030) and diabetes mellitus (aOR = 1.75; 95% CI = 1.33 to 2.29; p <0.001) are predictors of mortality in stroke patients.Conclusion: Obesity and diabetes mellitus are predictors of mortality in stroke patients.Keywords: obesity, diabetes mellitus, strokeCorrespondence: Karlinda. Masters Program in Public Health Sciences, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: karlindalinda8@gmail.com. Mobile: +6282278924093Indonesian Journal of Medicine (2019), 4(4): 383-393https://doi.org/10.26911/theijmed.2019.04.04.12
Two-Stage Reconstruction Surgery on Cervical Deformity Caused by Spondylitis TB Ermawan, Rieva; Utomo, Pamudji; Pradhana, Adhitya Indra; Islami, Umar Kharisma
Indonesian Journal of Medicine Vol. 5 No. 2 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Of all form of spinal tuberculo­sis (TB), cervical involvement is immensely rare and merely found in 3-5% of all cases. Kyphotic deformity in spondylitis TB was caused by ver­tebral destruction in the anterior segment due to infection that lead to hyperemia, bone marrow edema, and osteoporosis. Treatment of spinal TB was divided into two sections which run simultaneously, medicament and surgery. The use of cage for spinal surgery has shown its effectivity in supporting the anterior segment of vertebrae and providing long term stability. The purpose of this study was to compare functional out­come of two patients with cervical deformity caused by spondylitis TB that underwent two-stage reconstruction surgery with expandable and non-expandable cage. Case Presentation: Two patients were re­ported with cervical deformity caused by spon­dylitis TB in Orthopedic Hospital Prof. Dr. R. Soeharso, Surakarta. Both patients had their neurological status, Cobb angle, decompres­s­ion effects and post-operative fusion rate assessed. The patients were diagnosed with cervical deformity due to spondylitis TB showing the involvement of C4-5 in the first patient and C3-5 in the second one. Both underwent two-stage reconstruction surgery and were evaluated right after. There was no decadence in their post-operative neurological function. In the first patient, pre-operative Cobb angle was 44oand becoming 18o post-operatively. The pre-operative Cobb angle of the second patient was 14o and becoming 3o post-operatively.Results: Assessment of post-operative decom­pression effects and fusion rate were carried out by CT scan and both patients showed a favorable result even when they both were given a different cage. Although both cages had their own advantages based on surgical consi­deration, we prefer to used expandable cage due to minimal dissection needed.Conclusion: Two-stage reconstruction surge­ry using whether expandable or non-expand­able cage to treat cervical deformity caused by Spondylitis TB gave equally satisfactory out­come.Keywords: Spondylitis, tuberculosis, cervical deformityCorrespondence: Adhitya Indra Pradhana. Prof. Dr. R. Soeharso Orthopaedic Hospital. Jl. Jenderal Ahmad Yani, Surakarta 57162, Central Java, Indonesia. Email: adhityaindrapradhana@gmail.comIndonesian Journal of Medicine (2020), 05(02): 116-124https://doi.org/10.26911/theijmed.2020.05.02.04
Clinical Profile of Patients with Manus Fracture Caused by Firecracker Blast Utomo, Pamudji; Siswanto, Totok
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Fireworks are traditionally used by various cultures or groups for celebrations. Estimated 10,000 to 12,600 people are injured because of fireworks in America every year. The type of fireworks that cause the highest injury is firecrackers with the incidence rate of 30% to 67% of all cases of injury due to fireworks. Indo­nesia is a country with the largest Muslim popu­lation in the world and firecrackers are often used to welcome Ramadan and Eid al-Fitr. This study aimed to report the Clinical pro­file of patients with manus fracture caused by firecracker blast.Case Presentation: The case study was taken from patients of Karima Utama Surgical Hos­pital, Surakarta, Indonesia, during Ramadan and Eid al-Fitr (from May 14 to June 15) 2018. A total of 36 patients were fractured due to firework explosions recorded in medical records during that period. Data such as gender, age and fracture diagnosis were collected in this study.Results: Males have a higher prevalence of 28 (78%) than female 8 (22%), with the highest group age between 11 to 20 years with 11 cases (31%) and more than 60 years being the lowest age group with 2 (6 %) cases of a total of 36 res­pon­dents. The right hand as the dominant hand has an injury incidence rate of 31 (86%) com­pa­red to the left hand 5 (14%) and more often oc­curs single fracture 22 (61%) compared to mul­ti­ple fractures 14 (39%) including the amputated phalanx.Conclusion: Our study showed 36 patients had fractures of the manus due to firecrackers, with the majority of male victims 28 (78%) and single manus fractures 22 (61%) with the right-hand dominance at the age between 11 to 20 years.Keywords: manus fracture, firecrackerCorrespondence: Pamudji Utomo. Department of Orthopedics and Traumatology Prof. Dr. R. Soeharso Orthopedics Hospital, Surakarta. Email: utomodr­@ya­hoo.­com.Indonesian Journal of Medicine (2020), 05(01): 57-62https://doi.org/10.26911/theijmed.2020.05.01.09
THE EFFECTS OF ETHANOL EXTRACT AND ETHYL ACETATE FRACTIONATION OF SECHIUM EDULE JACQ. SWARTZ ON TRIGLYCERIDE LEVELS IN MALE RATS WITH TYPE 2 DIABETES MELLITUS Siahaan, Jekson Martiar; Julianto, Endy; Silitonga, Hendrika Andriana
Indonesian Journal of Medicine Vol 4, No 4 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: The prevalence of diabetes mellitus (DM) from year to year is increasing. Hyper­glycemia that occurs in DM is caused by oxidative stress that damages pancreatic ? cells. This situation can be controlled with synthetic hypoglycemic drugs, but it requires high medical costs. Therefore, alternative therapies that are easily available, relatively inexpensive, have potential anti-hypoglycemia and anti-cholesterolemia which is found in conjoined flasks (Sechium edule (Jacq.) Swartz) which contains flavonoids are needed. The purpose of this study was to analyze the effectiveness of ethanol extract and fractionation of ethyl acetate extracts of Sami (pumpkin) (Sechium edule (Jacq.) Swartz) as anti-hipoglycemia and anti-hypertriglycerides in white male wistar rats (Rattus novergius sp.) induced by STZ-NA-HFDD.Subjects and Method: A randomized controlled trial was conducted to assess the effectiveness of ethanol extract and fractionation of pumpkin fruit ethyl acetate extract. The sample included white male wistar rats (Rattus novergius sp.) Hyperglycemia induced by STZ-NA-HFD. The dependent variable was triglyceride levels. The independent variables were administration of ethanol extract and fractionation of pumpkin fruit ethyl acetate extract.Results: Ethyl acetate fraction 45 mg/kgBW better reduce triglyceride levels but statistically does not have significant differences between groups.Conclusion: The group that received Metformin and the group that was given ethanol extract 45 mg/kgBW had lower triglyceride levels compared to the other therapy and control groups.Keywords: Hipertrigliseridemia, diabetes mellitus, STZ-NA-HFDCorrespondence: Jekson Martiar Siahaan. Department of Physiology, Faculty of Medicine, Universitas Methodist Indonesia. Jl. Setia Budi Pasar II Tj. Sari, Medan 20132, North Sumatera. Email: Jekson.siahaansked­@­gmail.comIndonesian Journal of Medicine (2019), 4(4): 371-375https://doi.org/10.26911/theijmed.2019.04.04.10 
The Effect of Combination Avocado Juice Administration and Storytelling Therapy on Body Weight in Children with HIV/AIDS Warsini, Warsini; Ariasti, Dinar
Indonesian Journal of Medicine Vol. 5 No. 2 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: The incidence of HIV/AIDS is in­­­­creasing. In 2015 there were 30,935 new cases, 41,250 in 2016 and 33,660 in 2017, where new case findings were also found in children aged less than 4 years and caused child deaths world­wide in 2011 to reach 230,000. At present there is no treatment that can cure the disease, so vari­ous efforts are made to support the health and qua­lity of life of sufferers. The purpose of this study was to analyze the effect of providing a com­­bination of avocado juice and storytelling therapy on the weight of a child with HIV / AIDS.Subjects and Method: This was a quasy-experimental with pre-post test design. A sample of 15 children with HIV/AIDS was selec­ted for this study. The dependent variable was body weight. The independent variable was a combina­tion of avocado juice and storytelling therapy. Weight data was measured using weight scales. Data were analyzed using the Wilcoxon test.Results: Body weight (kg) after intervention (Mean= 26.17; SD= 9.30) was slightly greater than before intervention (Mean= 25.30; SD= 9.16), with p= 0.002.Conclusion: Combination of avocado juice and storytelling therapy increased body weight in children with HIV/AIDS.Keywords: storytelling therapy, avocado juice, children with HIV/AIDSCorrespondence: Warsini. Nursing Academy of Panti Kosala, Surakarta, Central Java. Alamat Instansi Jl. Raya Solo-Baki KM. 4 Gedangan, Grogol, Sukoharjo, Jawa Tengah. Email: warsinimulyono@­gmail.­com. Mobile: 0816418071Indonesian Journal of Medicine (2020), 05(02): 148-152https://doi.org/10.26911/theijmed.2020.05.02.09
Clinical Manifestation, Surveillance, and Complication in Tuberous Sclerosis Complex in Dr. Moewardi Hospital Hamidi, Baarid Luqman; Mirawati, Diah Kurnia; Danuaji, Rivan; Subandi, Subandi; Budianto, Pepi; Hambarsari, Yetty; Prabaningtyas, Hanindya
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Tuberous Sclerosis Complex (Bour­neville’s disease) is genetic disorder with autosomal pattern of heritence that affecting differentiation sellular in many organ such as brain, lungs, cardiac with varible severity. Birth incidence is estimated to be 1:6000. The purpose of this study was to reported a case of patients with Bourneville’s disease (tuberous sclerosis complex) in Moewardi Hospital. Also reported surveillance and complication in this patient.Case Presentation: A male, 18 yearsold, with seizures, onset from infancy, tonic secondary generalized seizure pattern simultaneously throug­h­out the body. Neurologic status exami­nation found right hemiparese and mental re­tarda­tion, Encountered in patients with skin disorders such as butterfly appearance with facial angiofibroma, forehead fibrous plaque dan shar­green patch. Abnormalities also appeared in the oral mucosa as multiple papules. When psych­ological tests patient had difficulty following instructions. Psychiatric examination showed mode­rate lower intelegence. EEG results slow waves at left parietal, there is severe electro­fisio­logic abnormality considered structural lesi­on in left parietal. CT showed multiple calci­fied nodul­es in subependymal right and left lateral ventri­cle. MRI showed  atrophy and left sclerotic hip­po­campus with glosis in sub cortex occipito left parietal. To overcome the seizure patients given Carbamazepine. There was in­creas­ing of trans­aminase enzim, liver suspect liver angio­myo­lipoma.Conclusion: Based on clinical criteria for definite tuberous sclerosis complex patients met the criteria. The patients responded positively to carbamazepine that reduced seizure frequency. But somehow, patient's prognosis is worst. Pre­sence of intellectual impairment and neuro­psy­chiatric problems is a potential poor epilepsy control, and liver disfunction so that the necessa­ry comprehensive management and surveillance involves other disciplines.Keywords:Tuberous sclerosis complex, con­genital disorder, epilepsy, mental retardationCorrespondence: Baarid Luqman Hamidi.Department of Neuro­logy, Dr. Moewardi Hospital/Faculty of Medi­cine, Universitas Sebelas Maret. Email: ba­arid@­staff.uns.ac.idIndonesian Journal of Medicine (2020), 05(01): 47-51https://doi.org/10.26911/theijmed.2020.05.01.07
The Effectiveness of Albendazole-Levamisole and Mebendazole-Levamisole on the Intensity of Trichuris trichiura Infection in Elementary School Children Anto, Endy Juli; Siahaan, Jekson Martiar; Silitonga, Hendrika Andriana
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Trichuris trichiura worm infec­tion is still a major public health problem in Indo­­nesia, especially in peripheral areas. Until now, the search for antihelmintic combinations that have a high healing ability against T. tri­chi­ura infections and in the search for truly effective worm­ing is still being done. Albendazole and Mebendazole single doses still show limited ef­fi­ca­cy in the treatment of T. trichuria worms. The combination of Albendazole with Levamisol can increase effectiveness, but this combination still needs further investigation. Based on that fact, it is necessary to study the effectiveness compa­rison of the degree of infection intensity between the treatment of Albendazol-Levamisol and Me­ben­dazol-Levamisol against T. trichiura.Subjects and Method: A double blind ran­domized control trial was conducted at the State Elementary School in Medan, North Sumatera, from April to October 2019. A sample of 60 children was selected for this study. The depen­dent variable was the number of eggs decreased, the cure rate, and side effects. The independent variables were Albendazole 400 mg-Levamisol 50 mg/ 100 mg and Mebendazole 500 mg-Levamisol 50 mg/100 mg. The stools of elementary school children were examined using the Kato-Katz method to find eggs of T. trichiura infection. Data analysis was performed using the Chi square test. Results: Samples in the Albendazol-Levamisol and Mebendazol-Levamisol groups were 30 children, respectively. Children infected with T. trichiura consisted of 58 children of mild in­tensity (96.7%) and 2 children of moderate inte­nsity (3.3%). On the results of stool examination, a significant difference in the number of eggs decreased in the two groups was obtained (p <0.001) and 96.7% was the cure rate for T. trichiura infection in the two groups of Alben­dazol-Levamisol and Mebendazol-Levamisol. In this study, there were no significant differences in side effects in the two treatment groups.Conclusion: Treatment of T. trichiura infection with single doses of Albendazol-Levamisol and Mebendazol-Levamisol showed that there were sig­nificant differences in the Number of D­ecreased Eggs. Meanwhile, for the cure rate, there was no difference between the Albendazol-Levamisol and Mebendazol-Levamisol groups.Keywords: T. trichiura, Albendazole-Levamisol, Mebendazole-LevamisolCorrespondence: Endy Juli Anto. Department of Parasitology, Faculty of Medicine, Universitas Methodist In­donesia, Medan, Indonesia. Email: dr.endy­julianto@gmail.com. Mobile: +62-823 6766-7575Indonesian Journal of Medicine (2020), 5(1): 17-23https://doi.org/10.26911/theijmed.2020.05.01.03
Fusi In Situ Posterior for Congenital Scoliosis with Wedge Hemivertebrae Using Single Rod and Pedicle Screw Instrumentation in Girl 2 Years Old: A Case Report Utomo, Pamudji; Dharma, Adi Surya; Ermawan, Rieva
Indonesian Journal of Medicine Vol. 5 No. 2 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Many spinal vertebral anoma­lies often occur, both scoliosis and kyfosis. In scoliosis, congenital abnormalities caused by hemivertebrae are the most common cause of abnormalities. The choice of treatment used can be either non-operative or operative. How­ever, non-operative treatment does not show satisfactory results to prevent the development of deformity. Operative treatment is an option that is considered to indicate more satisfying results. A variety of procedures such as in-situ posterior or with or without instrumentation anteroposterior fusions, combined anterior and poste­rior convex hemiepiphysiodesis and hemi­arthrodesis, and hemivertebral excision with fusion. Fusi In-situ posterior is a procedure option that is considered more beneficial for both surgeons and patients. This study aimed to evaluate the fusi in situ posterior for conge­nital scoliosis with wedge hemivertebrae using single rod and pedicle screw instrumentation in girl 2 year old.Case Presentation: Girl 2 year old with wedge hemivertebrae operated with fusion in situ posterior using single rod and pedicle screw instrumentation.Results: The operative treatment was per­formed on 2 hours operation time with amount of bleeding produced is 80 cc. There were no cranckshaft phenomena and no clinical and radological features suggestive of spinal ste­nosis. There were no major vascular or neuro­gical complications related to the pedicle screws. Then patient wore body jacket for limitation movement before fusion.Conclusion: Posterior situ fusion is perform­ed as convex fusion to avoid curve progression. Fusion in situ posterior using single rod and pedicle screw instrumentation. In congenital scoliosis is minimal blood loss, less traumatic, simple, safe and effective procedure. This study showed the early fusi in situ posterior of conge­nital scoliosis structural changes occur above or below can reduce fusion length, prevent curve progression and effectively achieve a more satisfactory correction without hazardous iatro­genic spinal stenosis, crankshaft phenomena, or neurological complications. Further research is needed to assess the progress of the outcome of surgeryKeywords: congenital scoliosis, wedge hemi­vertebrae, convex, fusi in situ posteriorCorrespondence: Pamudji Utomo. Department of Orthopaedic & Traumatology, Faculty of Medicine, Universitas Sebelas Maret/ Prof. Dr. R. Soeharso Ortho­pae­dic Hospital, SurakartaIndonesian Journal of Medicine (2020), 05(02): 125-130https://doi.org/10.26911/theijmed.2020.05.02.05
Multiple Hereditary Exostosis of Distal Ulna with Dislocation of Radial Head: A Case Report Utomo, Pamudji; Idulhaq, Mujaddid; Brilianto, Bagus Iman
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Multiple hereditary exostosis of the forearm is typically formed in the distal ulna causing disturbances in the growth of the ulna and functional disability. Multiple hereditary exo­stosis inhibits the growth of the ulna leading to an acquisition of a varus deformity in the ra­dius which sometimes leads to dislocation of the radial head, the development of limitations in the pronation-supination of the forearm, and cos­me­tic problems. This study aimed to report the mul­ti­ple hereditary exostosis of distal ulna with dis­location of radial head.Case Presentation: We present a case of a 14 year-old girl with main complaint of a bony prominence on her right elbow which limits the elbow flexion range of motion. 3D CT-Scan re­vealed a dislocation of radial head, shortening and posterior bowing of ulna. We performed excision of the prominent radial head, recons­truction, and temporary arthrodesis of the elbow.Results: The forearm deformity in patients with multiple hereditary exostosis related to the cross-sectional area of the distal ulnar physis was only one-quarter of the distal radius, the distal ulna is more involved in the condition. There was more longitudinal growth at the distal ulnar physis than at the distal radial physis, the distal ulnar physis contributed more total Ulnar Length than the distal radial physis did to Radial length. Known surgical interventions including simple excision, ulnar lengthening, corrective radial os­teo­­tomy, hemi-epiphyseal stapling of the distal radius, the Sauve-Kapandji procedure.Conclusion: Simple excision could improve the range of movement of the forearm but would not halt the progression of disease, particularly in younger patients. It was not effective in con­troll­ing progression of the deformity. Mature patients did not recur, but in patients that had been excis­ed before puberty the results were varied and unpredictable.Keywords: multiple hereditary exostosis, radial head dislocation, excisionCorrespondence: Pamudji Utomo. Department of Orthopaedics and Traumatology Prof. Dr. R.Soeharso Ortho­paedics Hospital, Surakarta. Email: utomodr­@yahoo.com.Indonesian Journal of Medicine (2020), 05(01): 63-69https://doi.org/10.26911/theijmed.2020.05.01.10