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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
Arjuna Subject : -
Articles 407 Documents
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THE EFFECT OF HOLISTIC PROGRAMS ON CORTISOL SERUM LEVELS IN POLYCISTIC OVARIUM SYNDROME Hadisaputro, Suharyo; Suwandono, Agus; Kurniawati, Erna Yovi
Indonesian Journal of Medicine Vol 4, No 4 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: The increasing prevalence of polycystic ovary syndrome (PCOS) in Indonesia reaches 8-10%. Patients with polycystic ovary syndrome are at risk of experiencing complex psychological disorders and decreased well-being. Psychological disorders in polycystic ovary syndrome are at risk of developing physical symptoms and increasing insulin resistance. The Holistic Program consists of a combination of diet yoga and remembrance therapy as an integrated holistic therapy. There is no non-pharmacological therapy that is holistically integrated to reduce serum cortisol levels in polycystic ovary syndrome. This study aimed to examine the effect of holistic programs on cortisol serum levels in polycistic ovarium syndrome.Subjects and Method: This was a randomized controlled trials conducted in Yogyakarta. A sample of 30 women patients with PCOS aged 19-40 years old was selected for this study. The sample was divided into 2 groups. The intervention group received holistic program for 14 days. The dependent variable was cortisol serum. The independent variable was holistic program. Cortisol serum and insulin levels were measure by ELISA method at the Integrated Research and Testing Laboratory, Universitas Gadjah Mada, Yogyakarta. Insulin resistance was calculated using the HOMA IR method. The data were analyzed by independent t-test and different test Paired t-testResults: Serum cortisol levels in the intervention group were lower than the control group. Serum cortisol levels decrease after the implementation of a holistic program.Conclusion: The holistic program that was carried out for 14 days in polycystic ovary syndrome is effective to reduce serum cortisol levels.Keywords: holistic program, cortisol serum, polycystic ovary syndromeCorrespondence: Erna Yovi Kurniawati. Masters Program in Applied Midwifery, School of Health Polytechnics, Ministry of Health Semarang. Jl. Tirto Agung, Pedalangan, Banyumanik, Semarang 50239, Central Java. Mobile: +6287739122352. Email: yovi.raharjanto@gmail.comIndonesian Journal of Medicine (2019), 4(4): 376-382https://doi.org/10.26911/theijmed.2019.04.04.11
Age-Related Sensory Impairment and Cognitive Decline in Geriatric Pratiwi, Dewi; Anggraini, Aulia Hervi; Bayu, Febri Arianto
Indonesian Journal of Medicine Vol. 5 No. 2 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Incidence of sensory impair­ment and cognitive decline were increase with aging, each would give a considerable impact on public health and quality of life especially in geriatric population. Several mechanisms have been proposed to account for the correlation between sensory impairment and cognitive decline and the common mechanisms were sensory deprivation, information degradation, cognitive load, resource allocation and or social isolation. Prolonged reductions in the quality or quantity of sensory input lead to cognitive deterioration due to neuronal atrophy. This study aimed to determine whether age related sensory impairment with cognitive decline.Subjects and Method: This was a cross-sectional study design conducted at geriatric clinic, Dr. Moewardi General Hospital, Sura­karta, from May 31 to July 1, 2018. A sample of 54 elderly aged ≥60 years old was selected by consecutive sampling. The dependent variable was cognitive decline. The independent varia­bles were presbyacusis, presbyastasis, olfactory impairment, diabetes, and hypertension. Pres­bycusis was measured by Pure Tone Audio­metry. Presbyastasis was measured by Dynamic Visual Acuity (DVA) test. Olfactory dysfunction was measured by sniffing test. Cognitive decline was assessed by MoCA-Ina questionnaire. The data were analyzed by Chi-square test.Results: The mean age of subjects was 70.5 years old ranging from 61-81 years old and most of the subjects were females (72.2%). Pure tone audiometry test revealed that 44.4% pati­ents had presbycusis. Dynamic Visual Acuity test showed that 25.9% patients had pres­byas­tasis. Sniffing test revealed that 29.6% patients had olfactory dysfunction. Presbyacusis (OR= 11.9; 95% CI= 1.3 to 105.5; p= 0.008) and olfac­tory dysfunction (OR= 10.8; 95% CI= 1.8 to 61.9; p= 0.002) increased cognitive decline, and they were statistically significant. Presbyas­tasis decreased cognitive decline (or= 0.9; 95% CI= 0.1 to 5.3; p= 0.948), but it was statis­tically non-significantConclusion: Sensorineural health may serve as a marker of brain aging therefore sensory measures can be used as screening tools for cognitive decline risk.Keywords: sensory impairment, presbycusis, presbyastasis, olfactory dysfunction, cognitive declineCorrespondence: Dewi Pratiwi. Department of Otorhinolaryngo­logy Head and Neck Surgery, Dr. Moewardi Hospital/ Faculty of Medicine, Universitas Sebelas Maret Surakarta, Central Java. Email: pratiwi­dewi81@gmail.comIndonesian Journal of Medicine (2020), 05(02): 153-161https://doi.org/10.26911/theijmed.2020.05.02.10
Mixed-Type Melasma Treated with Low Fluence Q-Switched Nd-YAG 1064 nm Laser: A Case Report Nugrahani, Aninda Fitri; Murlistyarini, Sinta
Indonesian Journal of Medicine Vol. 5 No. 2 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Melasma is an acquired, chro­nic hypermelanosis condition. Melasma is more common in women of all races and occur espe­cially on the face. The pathogenesis of melasma is very complex and the treatment is still a challenge. The purpose of this study was to report mixed-type melasma treated with low fluence Q-switched Nd-YAG 1064 nm laser.Case Presentation: A case of melasma in 54 year old woman was reported. Dermatological examination showed presence of brownish macules and patches in the centro facial area with symmetrical distribution. Examination with wood lamp showed mixed type. Patients have received topical therapy but there were no improvement.Results: The patient was then treated with low fluence Q-switched Nd-YAG 1064 nm laser for three sessions with an interval of 2 weeks. At 6 weeks of treatment the modified MASI (mMASI) value was reduced from 8.4 to 4.6 and the VAS value was increased from 2 to 8.Conclusion: The depth of the pigment deter­mined the response to therapy. In the mixed type melasma the response for therapy is only partial. The low-fluence Q-switched Nd-YAG 1064 nm laser can penetrate deeper into the dermis and damage melanin in a short time.Keywords: mixed typed melasma, low fluence, Q-switched Nd-YAG laserCorrespondence: Aninda Fitri Nugrahani. Department of Derma­tology and Venereology, DR. Saiful Anwar Hospital, Malang, East Java/ Faculty of Medi­cine, Universitas Brawijaya, Malang, East Java. Email: aninda16fitri@gmail.comIndonesian Journal of Medicine (2020), 05(02): 95-101https://doi.org/10.26911/theijmed.2020.05.02.01
To Pin a SCFE One Screw is Preferred than Two Screws in Children Nefihancoro, Udi Heru
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Slipped capital femoral epi­phy­sis (SCFE) is one of the most frequent hip dis­or­ders in children. SCFE is due to the dis­plac­ement of the epiphysis (femoral head that keeps its location in the acetabulum) relative to the me­taphysis (femoral neck) and shaft at the phy­sic level. Treatment seeks to prevent wor­sen­­ing of epiphyseal slippage on the meta­phy­sis, and percutaneous in situ fixation (ISF) using a single cannulated screw has long shown effi­cacy.Case Presentation: An 11 years old boy pre­sented with diagnosed with slipped capital fe­mo­ral epiphysiolysis of right hip and treated ope­­­ratively with one screw pinning guiding flu­o­­roscopy. Post operatively, from X-Ray eva­lu­a­tion confirmed the proper position without jo­int penetration. Patient is then advised to walk with crutches for gradual weight bearing to full weight bearing after 4 weeks. Then after 6 weeks, patient had already walked normally again.Conclusion: In unstable moderate-to-severe SCFE, the best reduction indications and tech­ni­­que remain controversial. There are many the­­ories supporting one or two screws pinning tech­­nique. In this case we used one screw pin­ning fixation with excellent result.Keywords: slipped capital femoral epiphysis, treatment, one screw in situ fixationCorrespondence: Udi Heru Nefihancoro. Department of Orth­o­pae­dic and Traumatology, Dr. Moewardi Hos­pi­tal/ Faculty of Medicine, Universitas Sebelas Ma­ret, Jl. Ir. Sutami 36A, Surakarta, Central Java, Indonesia. Email:udyhe­runefy@ymail.­com. Mo­bile: +62 816-672-767.Indonesian Journal of Medicine (2020), 5(1): 24-30https://doi.org/10.26911/theijmed.2020.05.01.04
THE EFFECTS OF TAMOXIFEN AND CHEMOTHERAPY AFTER SURGERY ON THE RECURRENCE AND SURVIVAL OF BREAST CANCER PATIENTS WITH POSITIVE HORMONE RECEPTOR: A META-ANALYSIS Delimasari, Trisakti Halimah; Tamtomo, Didik; Murti, Bhisma
Indonesian Journal of Medicine Vol 4, No 4 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Breast cancer is the most common type of cancer suffered by women in the world. The combination of tamoxifen and chemotherapy significantly reduces the risk of recur­rence and mortality in breast cancer patients. This study aimed to analyze how effective the com­bination of tamoxifen and chemotherapy after surgery to reduce the risk of recurrence and mortality in breast cancer patients with positive hormone receptor.Subjects and Method: This study used systematic review and meta-analysis. The researcher collected articles from the Pubmed journal database. The subjects of the study were women with breast cancer after surgery. The dependent variable was recurrence and survival (mortality). The independent variables were tamoxifen and chemotherapy. Data were analyzed based on the fixed and random effects model using RevMan 5 software.Results: There were 3 articles with 3,761 women who were involved in the analysis process. The combination of tamoxifen and chemotherapy could reduce the risk of recurrence in women with positive hormone receptor (ER+) breast cancer (HR=0.68; 95%CI=0.58 to 0.80; p=0.001). The combination of tamoxifen and chemotherapy showed weak and non-significant decreasing trend in reducing the risk of mortality in women with ER+breast cancer (HR=0.87; 95%CI=0.73 to 1.03; p= 0.11).Conclusion: The combination of tamoxifen and chemotherapy in women with ER+ breast cancer is effective in reducing the risk of recurrence. However, it does not increase survival.Keywords: tamoxifen, chemotherapy, breast cancer.Correspondence:Trisakti Halimah Delimasari. Program Studi Ilmu Kesehatan Kesehatan, Universitas Sebe­las Maret. Jl. Ir. Sutami 36 A, Surakarta 57126, Central Java. Email: tri­sak­ti­hd­1994­@g­mail.­com. Mobile: +6285 293 994 629.Indonesian Journal of Medicine (2019), 4(4): 346-353https://doi.org/10.26911/theijmed.2019.04.04.07
Difference of Calcium Levels in Infants with Low Birth Weight Nugraha, Sandi; Salimo, Harsono; Hidayah, Dwi
Indonesian Journal of Medicine Vol. 5 No. 2 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Hypocalcemia is a condition that can cause serious disorders, especially in new­borns. The occurrence of hypocalcemia is an event that often occurs in babies born that can be caused due to late parathyroid hormone function in calcium metabolism in the baby's body. Hypo­calcemia is often associated with hypotension and disorders of the heart rhythm, symptoms that are often seen are apnea, tachycardia, lethar­gy, vomiting, and gastrointestinal disor­ders. This study aimed to analyze differences in calcium level between low birth weight infants.Subjects and Method: A cross sectional study was conducted at Dr Moewardi Hospital, Sura­kar­ta, Central Java, from December 2016 to April 2017. A sample of 158 LBW children was selected using consecutive sampling. The dependent va­ria­­ble is a decrease in calcium levels. The inde­pen­dent variable is low birth weight babies. Data collected by medical records. Data were analyzed using multiple logistic regression.Results: Calcium level ≥1.13 mmol/L (OR= 0.30; 95% CI= 0.15 to 0.57; p <0.001), no seizures (OR= 0.20; 95% CI= 0.06 to 0.64; p = 0.004), and QoTC (OR= 0.20; 95% CI= 0.07 to 0.572; p= 0.003) decreased the risk of low birth weight.Conclusion: Calcium level ≥1.13, no seizures, and QoTC decrease the risk of low birth weight.Keywords: low birth weight, hypo­calcemiaCorrespondence: Sandi Nugraha. Department of Pediatrics, Uni­ver­sitas Sebelas Maret/ Dr. Moewardi Hospital, Surakarta. Phone/Fax.0271-633348. Email:sssa­n­di­nugraha@gmail.comIndonesian Journal of Medicine (2020), 05(02): 131-136https://doi.org/10.26911/theijmed.2020.05.02.06
Current Concept Management of Carpal Tunnel Syndrome: A Case Report Utomo, Pamudji; Surya, Wan Adi; Sumarwoto, Tito
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Carpal Tunnel Syndrome (CTS) is the most common median nerve compression neuropathy. CTS presents in 3.8% of the general population, affecting female more than male. CTS can be clinically or surgically treated, based on the severity of the disease. This study aimed to reported current concept management of carpal tunnel syndrome.Case Presentation: A 48 years old female presents with history of numbness on her left hand since 1 year ago, which were preceded by pain on her wrist. Her symptoms are worse at night, she often awakes because of the pain, and she shakes her hands for relief. The numbness was getting worse when she was working with her left hand. She also felt progressive decrease of sensation on her left hand. No systemic symp­toms are noted. On examination, there is obvious thenar muscles atrophy on her left hand. There is no weakness on motoric examination. Wrist and finger range of motion are within normal limit. She felt tingling sensation on her 3 radial digits with Tinel and Phalen maneuvers.Results: Non-operative treatments, like splint­ing, corticosteroid injection, exercise, and oral medication are still widely used and effective to reduce symptoms of CTS. For operative treat­ment, OCTR still become a standard treatment of severe CTS.Conclusion: Carpal tunnel syndrome manage­ment can be done by operative or non-operative treatments.Keywords: Carpal Tunnel SyndromeCorrespondence: Pamudji Utomo. Department of Orthopaedics and Traumatology Prof. Dr. R.Soeharso Ortho­paedics Hospital, Surakarta. Email: utomodr­@yahoo.com.Indonesian Journal of Medicine (2020), 05(01): 70-86https://doi.org/10.26911/theijmed.2020.05.01.11
Meta-Analysis: Effect of Probiotics on the Frequency and Duration of Diarrhea in Children Under Five Ciptaningtyas, Wahyu Agustin Dwi; Murti, Bhisma; Rahardjo, Setyo Sri
Indonesian Journal of Medicine Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Digestive tract disease is still a health problem around the world, currently there are 2,544,084 cases of diarrhea in Indonesia in 2016. In the Central Java region, there are an estimated of 911,901 cases of diarrhea, while 95,635 cases of diarrhea have been handled. This study aims to estimate the magnitude of the effect of probiotics on the frequency and duration of diarrhea among toddler based on the results of a number of similar previous studies.Subjects and Method: This study was a systematic study and meta-analysis, with PICO as follows: Population= children under five. Intervention= Probiotics. Comparison= Not Probiotic. Outcome= Frequency and Duration of Diarrhea in toddlers. The articles used in this study were obtained from several databases including PubMed, Springer Link, Cochrane Database, Hindawi, Elsevier, JBBA, LWW, Google Scholar. The keywords for search­ing articles are as follows: "Probiotic", OR "fre­quency", OR "diarrhea", "kid", OR child "AND" Randomized Controlled Trial (RCT). The articles included in this study were full text articles with a randomized controlled trial study design. Articles were collected using PRISMA flow diagrams. Articles were analyzed using the Review Manager 5.3 application.Results: A total of 12 articles reviewed in this meta-analysis study originated from India, Canada, Indonesia, America, Iran. Studies showed that the effect of probiotics decreased the frequency (Standarized mean difference -0.32; 95% CI= -0.67 to 0.03 p= 0.070). The effect of probiotics reduced the duration of diarrhea in children under five (Standarized mean diffe­rence= -0.74; 95% CI= -1.60 to 0.12 p= 0.090).Conclusion: Probiotics reduced the frequency and duration of diarrhea in toddlers.Keywords: Probiotics, Frequency, Diarrhea, ToddlersCorrespondence: Wahyu Agustin Dwi Ciptaningtyas. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126,  Central Java. Email: agustinfaa@gmail.com.Indonesian Journal of Medicine (2020), 05(04): 321-330https://doi.org/10.26911/theijmed.2020.05.04.07. 
Comparison of Pain in the Kocher and Midline Incisions in Patients with Post Cholecystectomy Yulianto, Agus; Raharjo, Agus; Alifianto, Untung; Supraptomo, RTH
Indonesian Journal of Medicine Vol. 5 No. 3 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Incision techniques that are of­ten used in cholecystectomy laparotomy are the Koc­her incision and midline incision. This study was carried out to compare the pain in the Kocher's in­cision and midline incision in patients with post­operative cholecystectomy laparotomy.Subjects and Method: : This study was an ob­ser­vational randomized controlled trial double sampling study conducted at the Department of Sur­gery Dr. Moewardi Hospital Surakarta in Octo­ber 2018 to February 2019. The sample of this study was 30 patients aged 18-65 years old who were diagnosed with symptomatic chole­lithiasis based on clinical, laboratory, and radio­logical tests. The samples were selected by simple ran­dom sampling. The dependent variable of this study was the pain. The independent variables were the Kocher and midline incision techniques. The pain was measured on a 24-hour post­ope­ra­ti­ve VAS scale, range 1-10. Data were analyzed by t-test.Results: There was no significant difference in pain level between the Kocher group (Mean= 2.33; SD=0.72) and the midline group (Mean= 2.20; SD=0.97) with p=0.192.Conclusion: There is no difference in pain level due to the Kocher incision technique and the mid­line incision technique.Keywords: pain, incision, kocher, midline, cholecy­stectomyCorrespondence: R. Th. Supraptomo. Anesthesia dan Intensive The­rapy Department Dr. Moewardi Hospital, Sura­karta. Jl. Kolonel Sutarto 132 Jebres, Surakarta, Central Java 57126. Email: ekasatrio@gmail.com. Mobile: 081229229567Indonesian Journal of Medicine (2020), 05(03): 240-245https://doi.org/10.26911/theijmed.2020.05.03.09  
Dietary Pattern As a Risk Factor of Diabetes Mellitus and Obesity: Meta-Analysis Septianawati, Linda Wahyu; Dewi, Yulia Lanti Retno; Pamungkasari, Eti Poncorini
Indonesian Journal of Medicine Vol. 6 No. 1 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Non-Communicable Disease is a disease that is considered unable to transmit or spread from one person to another but is a cause of death globally, especially diabetes mellitus and obesity. According to WHO, the number of deaths due to PTM in 2016 was 40.5 million (71%) worldwide. Diet is  one of the risk factors for Diabetes Mellitus and Obesity. This study aims to analyze the effect of diet as a risk factor for diabetes mellitus and obesity.Subjects and Method: This study was a syste­matic review and meta-analysis using a cross-sectional design. The articles used in this stu­dy were obtained from several databases, including PubMed, Google Scholar, Spring­er­link, and ScienceDirect. The articles used in this study were those published from 2011-2020. The article search was carried out by consi­dering the eligibility criteria defined using the PICO model. P: adults, I: unhealthy eating patterns, C: healthy eating patterns, and O: Diabetes Mellitus and Obesity. The keywords to search for articles were "dietary pattern", "risk", "obesity", and "diabetes mellitus," and "adjus­ted odds ratio". The articles included in this study were full-text articles with cross-sectional study design. Articles were collected using PRISMA flow diagrams. Articles were analyzed using the Review Manager 5.3 application.Results: A total of 15 articles were reviewed in this study. The meta-analysis showed that an unhealthy diet increased the risk of Diabetes (aOR= 1.65; 95% CI= 1.29 to 2.11; p <0.001). The meta-analysis of 9 articles also showed that an unhealthy diet increased the risk of obesity (aOR= 1.42; 95% CI= 1.21 to 2.66; p <0.001). This meta-analysis combines primary studies from Swaziland, China, Ethiopia, Kenya, Ame­rica, Malaysia, Ghana, Romania, Nepal, Ire­land, and Korea.Conclusion: Unhealthy diet is a risk factor for diabetes mellitus and obesity.Keywords: dietary pattern, diabetes mellitus, obesity, cross-sectionalCorrespondence: Linda Wahyu Septiananwati. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: lindatian81@gmail.com.Indonesian Journal of Medicine (2021), 06(01): 82-94https://doi.org/10.26911/theijmed.2021.06.01.09. 

Page 15 of 41 | Total Record : 407

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