Garuda - Garba Rujukan Digital

All

Jurnal Farmasi Indonesia

farmasi-indonesia
Website

Published by Universitas Setia Budi

ISSN : 16938615 EISSN : 23024291 DOI : -

Core Subject : Health, Science, Engineering,

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology

Jurnal Farmasi Indonesia (e-ISSN : 2302-4291 dan ISSN : 1693-8615) merupakan jurnal yang dikelola oleh Fakultas Farmasi, Universitas Setia Budi yang terbit sejak Februari 2004 dan terbit 2 kali dalam setahun yaitu periode bulan Maret dan November. Jurnal Farmasi Indonesia menerima naskah tentang hasil penelitian laboratorium, lapangan, studi kasus, telaah pustaka yang erat kaitannya dengan bidang kefarmasian, kesehatan dan lingkungan hidup.

Arjuna Subject : -

Articles 271 Documents

13 14 15 16 17

Strategi Pengembangan Akreditasi Manajemen Penggunaan Obat Dengan Metode Hanlon Di IFRSUD Sultan Imanuddin Pangkalan Bun Poppy Dwi Citra Jaluri; R.A. Oetari; Gunawan Pamudji Widodo
Jurnal Farmasi Indonesia Vol 13 No 1 (2016): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

To improve the quality of services and improve patient safety in providing hospital services needed hospital accreditation. The purpose of this study was to determine the level of conformity seven accreditation standards MMU based from KARS and strategy development pharmacy installation with Hanlon method. This study is a non-experimental research design in Hospital Pharmacy Installation Sultan Imanuddin Pangkalan Bun, Central Kalimantan, data collection conducted by using a questionnaire instrument to 28 respondents are Pharmacists and TTK. After the problem was found in each element and then analyzed using the Hanlon method. Research concluded that the level suitability to the accreditation standards of pharmacy service MMU is MMU1 85.36%, 92.39% MMU2, MMU3 78.75%, 88.57% MMU4, MMU5 50.24%, 72.32% MMU6, and MMU7 42.62% and development strategy appropriate priorities to be applied in IFRSUD Sultan Imanuddin Pangkalan Bun, Central Kalimantan are still does not meet the maximum standards.

Studi Aktivitas Antibakteri Ekstrak Etanolik, Ekstrak Metanol dan Infus Daun Bayam Duri (Amaranthus spinousus) dan Herba Cakar Ayam (Sellaginella doederleinii Hieron) terhadap Bakteri Penyebab Pneumonia Opstaria Saptarini
Jurnal Farmasi Indonesia Vol 8 No 1 (2011): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Pneumonia is a respiratory system disease which the alveoli become inflamed and have fluid accumulation. Pneumonia is a serious infection that affects many children and adults in a fundamental way around the world. There are many bacteria that cause diseases such as pneumonia, among others, are used in this test are Streptococcus pneumonia, Klebsiella pneumonia, Streptococcus haemolyticus alpha and beta. Plants used in this study are bayam duri leaves and cakar ayam herbs. Mikrodilusi methods used for testing antibacterial activity. The test is performed to extract ethanol, methanol extracts and infusions of leaves patikan kebo and herbaceous rumput mutiara with the same concentration with the largest concentration is 1024 ug / ml following concentration by dilution continued until the third column will have the smallest concentration. Plates were incubated at 37 Â° C for 24 h and then observed the clear (no microbial growth). The smallestconcentration at which no visible microbial growth defined as the MIC (NCCLS, 2003). Based on the testing of antibacterial activity of the infusion, methanol extract and ethanol extract of leaves of bayam duri leaves and cakar ayam herbs, with the broth method microdillution, it appears that the most active extracts were ethanolic extract of bayam duri leaves and ethanolic extract cakar ayam herbs on the bacteria Streptococcus pneumoniae, Streptococcus haemolyticus alpha and Streptococcus haemoyiticus beta, and Klebsiella pneumonia although the effect is lower than the standard drug tetracycline.

Formulasi Krim Ekstrak Buah Mengkudu (Morinda citrifolia L.) sebagai Antioksidan Dewi Ekowati; Dwi Ningsih
Jurnal Farmasi Indonesia Vol 11 No 1 (2014): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Noni (Morinda citrifolia L.) has long been known as a nutritious plants. Noni has known contain ascorbic acid and Î² - carotene as an antioxidant function. The purpose of this research is to create a cream preparation with qualified physical properties and stability of extracts of noni as an antioxidant. The noni fruit extract was made cream in three formula with concentrations of 5%, 7,5%, and 10%. The physical properties and stability testing of the cream were viscosity, dispersive power, pH and viscosity changes. Antioxidant activity of noni fruit extract cream was tested by DPPH method. The results showed that the noni fruit extract could made cream until concentration of 10%. The noni fruit extrac creams had antioxidant activity. Formula III contained noni fruit extract was the best formula which had antioxidant activity with IC50 value of 69,61 mg/mL.

Pengaruh Superoksida Dismutase Rekombinan Staphylococcus equorum Terhadap Viabilitas Sel dan Deposisi Kolagen Pada Sel Fibroblas 3T3 Yang Dipaparkan UVA Ana Indrayati; Sukmadaja Asyarie; Tri Suciati; Debbie Soefie Retnoningrum
Jurnal Farmasi Indonesia Vol 13 No 1 (2016): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

UVA is the main external factors causing skin aging. UVA increase matrix metalloproteinase (MMP) synthesis that degrade collagen indirectly through reactive oxygen species. Superoksida dismutase (SOD) catalyzes the conversion of superoxide anions to hydrogen peroxide and oxygen. SOD can be used as a cosmeticâ€™s component to prevent skin aging. The objective of this research to determine rSOD S. equorum ability to increase collagen deposition using fibroblast 3T3 against UVA. The research was initiated by the confirmation of E. coli BL21(DE3) carrying pJExpressÂ®414-sod. rSOD was overproduced in E. coli BL21(DE3) by IPTG induction to a final concentration of 1 mM for 4 hours at 37oC. rSOD purification was done using an Ni-NTA affinity column with gradient imidazole concentrations for elution. Various concentrations of rSOD was added to fibroblast 3T3 cell culture after UVA irradiation to determine its role in collagen deposition. The effect of rSOD was analyzed by fibroblast viability using Alamar blue and collagen deposition with picro sirius red. The results showed that fibroblast cell viability exposed with UVA for 45 minutes in the presence of 4, 8, and 16 unit rSOD was not significantly affected, however, the collagen deposition was significantly increased about 3.02%; 20.03% and 35.75% respectively compared to cell without rSOD. This result indicates that rSOD is a good candidate for an anti photoaging agent.

Kepuasan Pasien Peserta JKN Pada Mutu Pelayanan Kefarmasian di Puskesmas Induk Wilayah Surakarta Nila Darmayanti Lubis; Santi Dwi Astuti
Jurnal Farmasi Indonesia Vol 15 No 1 (2018): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

In the era of National Health Insurance, health development in the field of medicine, amongothers, aims to ensure the availability of medicines to achieve satisfactory service targets. Thesurvey of the Directorate General of Pharmacy and Medical Devices at the Ministry of Healthshows that health care centers that have implemented pharmaceutical services according to thenew standards have reached 25%. The purpose of this study was to determine the percentage ofpatient satisfaction of participants of the National Health Insurance in the quality of pharmacyservices at the Parent Community Health Center in Surakarta.This research is a quantitative study, data obtained concurent. Primary data were obtainedfrom questionnaires filled by outpatient National Health Insurance patients. Informants wereselected using purposive sampling technique. Questionnaire data was processed then comparedbetween the services obtained by the patient and the services expected by the patient, after whichthe results were presented in the form of a Cartesian diagram.Through this research, 90.23% of National Health Insurance patients at the Surakartaprimary health center expressed satisfaction with the quality of their pharmaceutical services andservices in accordance with patient expectations.

Aktivitas Fraksi Nonpolar dari Ekstrak Etanol Akar Dadangkak (Hydrolea spinosa L.) terhadap Penurunan Kadar Glukosa Darah Tikus Jantan yang Diinduksi Aloksan Muhammad Zaini; Vivi Shofia; Amalia Ajrina
Jurnal Farmasi Indonesia Vol 15 No 1 (2018): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

The roots of Dadangkak (Hydrolea spinosa L.) empirically have been used by Kalimantan people to cure diabetes. The purpose of this research is to examine the effect of fractions ratio from ethanol extract. The research started from extraction of the roots of Dadangkak (250 grams) by materation using ethanol. From that extraction yielded 16.62 grams of ethanol extract. Ethanol extract had been fractionated with n-hexane and petroleum ether. The antidiabetic assay using 20 Wistar mice that had been divided into 4 groups : Aquadest 2 ml/200 grams of weight is given to the first group, Glibencalmide 0.45 mg/kg BW is given to the second group, n-hexane fraction 100 mg/kg BW is given to the third group and petroleum eter 100 mg/kg BW is given to the forth group. Before all of groups had been given treatments, the mice had been induced by Aloxan 150 mg/kg BW intraperitoneally. The forth day after being induced, mice also given control and fractions treatments for 7 days perorally. The measurement of blood glucose level had been done at the first, forth, and twelfth day after being induced using Gluco-DR. The blood glucose level had been tested by SPSS with 95% confidence level. The result of this research showed the average of blood glucose level by the n-hexane fraction is 189,8 ± 13,59 mg/dL and petroleum ether is 437,6 ± 8,98 mg/dL. n-hexane fraction could decrease the blood glucose level of mice significantly (sig<0.05) compared to the control group. On the other side, the giving of petroleum ether fraction is not showing the decrease of blood glucose level significantly (sig>0.05).

Kesesuaian Biaya Riil Terhadap Tarif INA-CBGS Pada Pasien Hipertensi di Rumah Sakit Umum Daerah Pandan Arang Boyolali Tahun 2017 Isma Oktadiana; Oetari Oetari; Andayani Andayani
Jurnal Farmasi Indonesia Vol 16 No 2 (2019): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

In Indonesia, the incidence of hypertension ranged from 6-15% and many patients are still not reached by health services, especially in rural areas. The research purposes to determine patterns of treatment of hypertension, the average cost of treatment, the factors that affect the total cost, and the cost of compliance with the real cost of the package INA-CBGs. The study was an observational cross-sectional study design according to the perspective of the hospital. Method of data collection was done in retrosfektif and data derived from quantitative data. Subjects were inpatients suffering from hypertension without comorbidities and hypertension with comorbid diabetes mellitus, heart failure and kidney failure. The results showed significant differences with the INA-CBG rates on total costs in outpatients differed significantly in 79 samples, while the real cost of Rp 335,145 was greater than the INA-CBGs rate of Rp. 181,400, while inpatients differed significantly in 63 samples at the grade I, grade 3, 2, 1 severity of Rp. Rp. , Rp. 1,438,069, Rp. 1,498,683, Rp. 2,000,685, the severity level II class 3 and class 1 was Rp. 1,540,134, Rp. 2,866,200, III and grade 1 III severity levels of Rp. 1,586,617 and Rp. 3,439,500. This difference shows a positive difference, where the total real cost is more.

AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SURUHAN (Peperomia pellucida L. Kunth) TERHADAP BAKTERI Staphylococcus aureus Isna Jati Asiyah; Destik Wulandari
Jurnal Farmasi Indonesia Vol 16 No 2 (2019): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

ABSTRACT Staphylococcus aureus causes infectious diseases include breast inflammation (mastitis), endocarditis, respiratory tract infections, and infections of the skin. Drug from natural resources need because β-lactam group antibiotic activity had been resistance to S. aureus. The herb plants (Peperomia pellucida L. Kunth) has active tannins and flavonoids act as antimicrobials. This research aims to determine antibacterial activity of leaf extract (Peperomia pellucida L. Kunth) against S. aureus. The leaf leaves were extracted by maceration using 70% ethanol solution, then an antibacterial test was carried out using the dilution method to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). Extracts was made in 5 series concentration: 100%, 80%, 60%, 40%, and 20%. The results showed MIC value could not be determined because the mixture between the leaf extract and S. aureus bacteria was very cloudy. MBC obtained from the antibacterial activity test of leaf extract on S. aureus bacteria was 40%.

Aktivitas Antibakteri Ekstrak Dan Fraksi Herba Kemangi (Ocimum Sanctum L) Terhadap Staphylococcus Aureus Dan Pseudomonas Aeruginosa Taufik Turahman; Ghani Nurfiana Fadma Sari
Jurnal Farmasi Indonesia Vol 16 No 2 (2019): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Infectious disease is still one of the public health problems, especially in developing countries. Etiology is generally caused by Staphylococcus aureus and Pseudomonas aeruginosa. Basil (Ocimum sanctum L) is a plant known as lalapan which has antioxidant, anticancer and antimicrobial properties but there is not much scientific information as an antibacterial. This study aims to determine the chemical content and antibacterial activity of ethanol extract, n-hexane fraction, ethyl acetate and basil herb water on the growth of Staphylococcus aureus and Pseudomonas aeruginosa by diffusion and dilution. Herbs are macerated using 96% ethanol. The extract obtained was then suspended with water and then fractionated with n-hexane and ethyl acetate. Basil extract and the fractions obtained were then tested for antibacterial activity at concentrations of 12.5%, 25% and 50% using the diffusion method. The MIC and MBC of the most active fractions can be known using dilution tests with concentrations of 0.78, 1.56, 3.125, 6.25%, 12.5%, 25% and 50%. Ciprofloxacin positive control 5μg/15μl and negative control using sterile 80% 5% tween. Identification of groups of compounds is done by the test tube method. Antibacterial activity test results showed that the zone of inhibition zone in gram-negative bacteria in general tends to be larger than gram-positive bacteria. The largest inhibition zone diameter in the bacterium Pseudomonas aeruginosa in the ethyl acetate fraction basil concentration 50% with a diameter of inhibition zone (10 mm), in the Staphylococcus aureus bacteria found in the ethyl acetate fraction at a concentration of 50% has inhibitory power of (8.6 mm). The results of the identification of the chemical content showed that the extract and fraction of basil herbs contain flavonoids, saponins and steroids and tannins Keywords: Antibacterial, Basil (Ocimum sanctum L), Staphylococcus aureus, Pseudomonas aeruginosa

Efek Ekstrak Etanol Daun Kelor (Moringa oleifera, Lamk.) Pada Mencit Model Demensia: Kajian Memori Spasial, Kadar Malondialdehid Dan Jumlah Sel Piramidal Hipokampus Area CA1 Dan CA2-CA3 arikha ayu susilowati; Gunawan Pamudji Widodo; Jason Merari
Jurnal Farmasi Indonesia Vol 16 No 2 (2019): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

ABSTRACT Dementia is a disease of nerve cells in the brain, due to the hippocampus damaged by free radicals. EEDK (Ethanol extract of kelor leaves)(Moringa oleifera, Lamk.) contains phytochemicals, carotene, vitamins, minerals, amino acids, flavonoids and phenolics, proven to reduce oxidative damage and memory deficits. This study aims to determine the effect of EEDK on spatial memory, MDA levels, the number of hippocampal pyramidal cells damaged in the CA1, CA2-CA3 area and histopathological features of mice. The design of this study was pre-test and post-test control group design for spatial memory test and post test control group design for MDA levels, hippocampal pyramidal cell counts and histopathological features. This Reseach using 30 mice divided into of 6 groups, each group consist of 5 mice, namely the normal control group, positive control, negative control, EEDK group 100, 200, and 400 mg/kg body weight, all groups induced by Pb acetate 50 mg / KgBB except the normal group. Positive control was treated with quercetin 50 mg/kgBB, while negative controls were not treated. Memory test data obtained from the Morris water maze pre and post-test, antioxidant status data obtained from MDA levels and histopathological data obtained from the calculation of pyramidal cell counts. Data analysis used repeated measures ANOVA and ANOVA with Post Hoc LSD. The results showed that latency time, MDA level test and brain histopathology examination had significant differences between the negative control group and the EEDK group. EEDK 400 mg/kgBB was most effective in improving spatial memory, decreasing MDA levels, and preventing damage to the hippocampal pyramidal cell CA1, CA2-CA3 area.

Page 15 of 28 | Total Record : 271

13 14 15 16 17

Filter by Year

2009 2024

Filter By Issues

All Issue Vol 21 No 2 (2024): Jurnal Farmasi Indonesia Vol 21 No 1 (2024): Jurnal Farmasi Indonesia Vol 20 No 2 (2023): Jurnal Farmasi Indonesia Vol 20 No 1 (2023): Jurnal Farmasi Indonesia Vol 19 No 2 (2022): Jurnal Farmasi Indonesia Vol 19 No 1 (2022): Jurnal Farmasi Indonesia Vol 18 No 2 (2021): Jurnal Farmasi Indonesia Vol 18 No 1 (2021): Jurnal Farmasi Indonesia Vol 17 No 2 (2020): Jurnal Farmasi Indonesia Vol 17 No 1 (2020): Jurnal Farmasi Indonesia Vol 16 No 2 (2019): Jurnal Farmasi Indonesia Vol 16 No 1 (2019): Jurnal Farmasi Indonesia Vol 15 No 2 (2018): Jurnal Farmasi Indonesia Vol 15 No 1 (2018): Jurnal Farmasi Indonesia Vol 14 No 2 (2017): Jurnal Farmasi Indonesia Vol 14 No 1 (2017): Jurnal Farmasi Indonesia Vol 13 No 2 (2016): Jurnal Farmasi Indonesia Vol 13 No 1 (2016): Jurnal Farmasi Indonesia Vol 12 No 2 (2015): Jurnal Farmasi Indonesia Vol 12 No 1 (2015): Jurnal Farmasi Indonesia Vol 11 No 2 (2014): Jurnal Farmasi Indonesia Vol 11 No 1 (2014): Jurnal Farmasi Indonesia Vol 10 No 2 (2013): Jurnal Farmasi Indonesia Vol 9 No 1 (2012): Jurnal Farmasi Indonesia Vol 8 No 2 (2011): Jurnal Farmasi Indonesia Vol 8 No 1 (2011): Jurnal Farmasi Indonesia Vol 7 No 2 (2010): Jurnal Farmasi Indonesia Vol 7 No 1 (2010): Jurnal Farmasi Indonesia Vol 6 No 3 (2009): Jurnal Farmasi Indonesia Vol 6 No 1 (2009): Jurnal Farmasi Indonesia More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota surakarta,

Jawa tengah

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota surakarta, Jawa tengah INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota surakarta,

Jawa tengah

INDONESIA