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Eksakta : Berkala Ilmiah Bidang MIPA
Published by Universitas Negeri Padang
ISSN : -     EISSN : 25497464     DOI : https://doi.org/10.24036/eksakta/
Core Subject : Science, Education, Agriculture, Social, Engineering,
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Energy Engineering Environmental Science Materials Science & Nanotechnology Mathematics Mechanical Engineering
Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464) is an open access journal and peer-reviewed that publishes either original article or reviews. The journal is dedicated towards dissemination of knowledge related to the advancement in scientific research. The prestigious interdisciplinary editorial board reflects the diversity of subjects covered in this journal. Under the realm of science and technology, the coverage includes environmental science, pure and applied mathematics, agricultural research and engineering, biology, biotechnology, bioinformatics, Healthcare sciences (including clinical medicine, preventive medicine & public health), physics, biophysics, computer science, chemistry and bioengineering, to name a few. This Journal Is Published at 3 Month intervals on January-Marc, April-June, July-September and October-December
Arjuna Subject : Umum - Umum
Articles 310 Documents
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6-Gingerol Slightly Reduces Hepatic Endoplasmic Reticulum Stress Markers in Rats with High-Fat, High-Fructose Diet-Induced Metabolic Syndrome Ahmad, Nouman; Syarifah Dewi; Soetikno, Vivian
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 01 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss01/581

Abstract

Metabolic syndrome (MetS) is linked to hepatic endoplasmic reticulum (ER) stress. This study evaluated 6-gingerol’s potential to alleviate ER stress in a high-fat high-fructose (HFHF)-induced MetS rat model. Male Sprague-Dawley rats (8 weeks, 180–220 g) were assigned to five groups: Normal, HFHF, and HFHF with 6-gingerol (50, 100, or 200 mg/kg). The Normal group received a standard diet, while others had HFHF for 16 weeks. From Week 8, intervention groups received 6-gingerol daily. Except for Normal, other groups also received Streptozotocin (22mg/kg, i.p.) at Week 8. At Week 16, rats were euthanized, and liver tissues collected to assess ER stress markers (GRP78, IRE1, TRAF2, PERK, CHOP) via qPCR and apoptotic markers (Bax, Bcl-2) via ELISA. 6-Gingerol slightly reduced liver ER stress markers, including GRP78 (P=0.392), CHOP (P=0.798), IRE1 (P=0.419), TRAF2 (P=0.470), and PERK (P=0.357), but these changes were not significant. Similarly, apoptotic markers Bax and Bcl-2 showed no significant differences, though the Bax/Bcl-2 ratio decreased (P=0.186). These results indicate that 6-gingerol had only a slight effect on ER stress and apoptosis within the parameters of this experiment.
The Combination of Bay Leaf (Syzgyum polyanthum) and Noni Fruit (Morinda citrifolia) in Lowering Cholesterol Levels in Balb/C Hypercholesterolemia Mice Noor, Ainullatiffah; Nanik Lestariningsih; Lilin Ika Nur Indahsari
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 01 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss01/557

Abstract

Central Kalimantan is rich in natural resources of potential medicinal plants, such as bay leaf and noni. These medicinal plants have been used traditionally. However, there is minimal scientific evidence about their use as a medicine due to limited research. The current research aims to identify the influence of applying a combination of bay leaf and noni fruit extract in lowering cholesterol levels in Balb/c hypercholesterolemic mice. The research employs a mixed method, namely explorative and experimental research. The research subjects are 28 female Balb/c mice in a hypercholesterolemic condition. The research consists of 7 treatments, namely positive control, negative control, P1 (20%), P2 (30%), P3 (40%), P4 (50%), and P5 (60%) with 4x repetitions. It combines the extract of bay leaf and noni fruit to lower cholesterol levels in the research subjects. Data analysis uses one-way ANOVA. The research results indicate that the application of a combination of bay leaf and noni fruit extract has a significant influence on the reduction of cholesterol levels in hypercholesterolemic mice with a p-value α (α 0.05) of 0.000. The concentration effective in lowering the cholesterol levels in hypercholesterolemic mice is in concentration P7 (60%) with a reduction of 59.25 mg/dL.
Application of Nipah Pseudovirus System for Development of Antibody Neutralization Assay Anna, Shoffiana Noor; Fera Ibrahim
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 01 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss01/569

Abstract

Nipah virus (NiV) is a type of virus that can make people and many animals very sick.  It can cause serious breathing problems and brains welling.  Because of how dangerous and deadly it is, the World Health Organization (WHO) sees NiV as a global healthrisk.  It needs to be handled in special labs that have the highest safety measures, called Biosafety Level-4 (BSL-4) facilities.  Rightnow, there isn't a good vaccine or treatment available for NiV.  It could be a health risk for Indonesia since it has been found in nearby countries. Indonesia doesn't have a BSL-4 lab yet. So, we need a way to evaluation NiV vaccine that can be done in a BSL-2 lab.  The NiV pseudovirus (PV NiV) has special proteins that help it attach to and enter mammal cells.  It is made using a system based on HIV and includes a signal detector.  This setup can help create tests to measure how well antibodies work against NiV.  It can also be used to monitor infections, check community immunity, develop NiV vaccines, and research new treatments to fight NiV infections.
Kaolinite Nanotubes as Support Catalysts of Sulfuric Acid (H2SO4) for Transesterification Reaction of Waste Cooking Oil into Methyl Ester for Biodiesel Fitri, Ernarisa; Rahadian Zainul; Syukri
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 02 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss02/577

Abstract

This study aims to improve the catalytic performance of kaolinite by converting it into kaolinite nanotubes and utilizing it as a support for sulfuric acid catalysts. Analysis using XRD and TEM revealed that the kaolinite crystal phase remained stable after being modified with sulfuric acid, while kaolinite nanotubes underwent little structural change. In addition, characterization via FTIR and XRF confirmed the presence of sulfate ions in kaolinite nanotubes and kaolinite after combination with sulfuric acid. Catalytic test on transesterification of used cooking oil under uniform conditions (catalyst 3% w/v, oil to methanol ratio 1:6, temperature 90 °C, and stirring speed 700 rpm) showed that sulfuric acid supported by kaolinite nanotubes gave the best performance, producing methyl ester of 65.01%. These findings indicate that converting kaolinite into nanotubes significantly improves its performance as a catalyst support. Practically, this increase in catalytic activity contributes to the efficiency of used cooking oil-based biodiesel production, which can reduce dependence on virgin vegetable oil raw materials and support waste oil recycling efforts. In addition, the use of cheap and easily available kaolinite-based catalysts can reduce the cost of biodiesel production, making it more competitive as an environmentally friendly fuel.
Study of Indonesian Rhododendron: Classification, Conservation, and Pharmacology Activity Birhi, Damiana Nofita; Meike Tiya Kusuma; Antonia Fransiska Laka
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 02 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss02/583

Abstract

Rhododendrons are representatives of ornamental plants with a wide range of pharmacological activities. Indonesia is the second richest country in Rhododendron plants with 233 species. Unfortunately, more than 85 species are severely lacking in data, 21 species are vulnerable, and more than 30 others are endangered or even no longer found. The purpose of this study is to review the species that have been found in Indonesia, and find the factors that affect conservation efforts to prevent the extinction of this plant. The results of the study succeeded in recording 221 species that had been found in Indonesia with 4 of them not having sufficient data so that named Rhododendron sp1, R. sp2, R. sp3 and R. sp4 by local residents. Four species were confirmed to be extinct, and most of the ex-situ conservation efforts unsuccessful. The results of this study show that there is need for cooperation between the government and residents around the Rhododendron growing location in an effort to preserve this plant. Researchers are also expected to pay more attention to this plant considering it has bioactive compounds with very high pharmacological properties.
Distribution of blaCTX-M, blaSHV, blaTEM genes in Extended Spectrum β-Laktamase Producing Klebsiella pneumoniae from Clinical Isolates in Jakarta Engel, Yulia; Conny Riana Tjampakasari; Fithriyah Sjatha
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 02 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss02/549

Abstract

Klebsiella pneumoniae is one of the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) due to their high level of antibiotic resistance. Ceftriaxone is one of the cephalosporin antibiotic that functions inhibit bacterial cell wall synthesis and used for treating K. pneumoniae infections. Resistance to ceftriaxone in K. pneumoniae has been widely reported, with one contributing factor being the production of β-lactamase enzymes encoded by the genes blaCTX-M, blaSHV, and blaTEM. This study characterized the presence of these genes  in 12 clinical isolates of         K. pneumoniae and analyzed their correlation with phenotypic resistance to ceftriaxone. All isolates characterized with antimicrobial susceptibility testing (AST) and disk diffusion methods to evaluate the phenotypic production of blaCTX-M, blaSHV, and blaTEM. Molecular analysis using the polymerase chain reaction (PCR) method showed the genes blaCTX-M and blaTEM were detected in 11 isolates (91.67%), and blaSHV was found in 9 isolates (75%). The distribution pattern of the blaCTX-M, blaSHV and blaTEM resistance genes was present in 8 isolates (66.67%), with MIC values > 64 µg/mL. The presence of blaCTX-M, blaSHV, and blaTEM genes together in K. pneumoniae isolates represents a potential risk for resistance to other β lactam antibiotics.
Optimization of Photovoltaic Cells Using Copper-Aluminium Electrodes and Magnesium Sulfate-Based Gel Electrolytes Yanni, Fitri; Rahadian Zainul
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 02 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss02/573

Abstract

Photovoltaic cells are devices that can convert sunlight energy into electrical energy by applying the photovoltaic principle. Indonesia is a country located on the equator that receives a lot of sunlight every year. However, so far the source of electrical energy comes from fossil fuels whose availability is limited. So a material is needed that can improve the performance of photovoltaic cells in producing electrical energy. The purpose of this study was to review the advantages of using Cu-Al electrodes and MgSO4 electrolytes and to find factors that affect the efficiency or performance of photovoltaic cells. This article includes references to articles from 2018 to 2025. The results showed that the use of Cu-Al electrodes and MgSO4 electrolytes can increase cell efficiency. In addition, Cu-Al and MgSO4 are materials that are easy to find and cheap so that they can reduce the cost of making photovoltaic cells compared to other conventional materials that have quite high prices. It is hoped that researchers can utilize this material considering that it has great potential to produce energy in future life.
Chemical Components and Antibacterial Activity of Cinnamomum culilaban Extract from Southeast Maluku Kapelle, Imanuel Berly Delvis; Shielda Natalia Joris; Fauzan Saleh; Nini Munirah Renur
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 02 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss02/584

Abstract

The bark of Cinnamomum culilaban, endemic to Southeast Maluku, has the potential as an antibacterial. This study aimed to determine the antibacterial activity of C. culilaban bark extract isolated using distillation and maceration methods and to determine the chemical components contained therein. Qualitative tests using GCMS and antibacterial activity testing against E. coli and S. aureus bacteria. The extraction results using the distillation method obtained a sedimentation of 3.28% and the maceration method of 28.03%. The chemical components of the distillation extract showed four main components: Eucalyptol 4.02%, (+)-2-Bornanon 2.32%, terpineol 1.49% and Safrole 86.78%. The chemical components of the maceration extract have five main components, namely (+)-2-Bornanon 1.35%, Terpineol 1.43%, Safrole 89.06%, Spathulenol 1.26%, and Methoxyeugenol 1.73%. The antibacterial activity of the distillation extract against E. coli bacteria is classified as strong, with the highest inhibition zone size at a concentration of 60% (13.47 ± 1.14 mm). In contrast, for S. aureus bacteria, there is no antibacterial activity. The antibacterial activity of the maceration extract against S. aureus bacteria is classified as strong with the inhibition zone size at a concentration of 100% (11.87 ± 1.15 mm). In contrast, for E. coli bacteria, there is no antibacterial activity.
Measurement of C-Organic Content in Sediment as an Indicator of Carbon Absorption Potential in the Bonto Bahari Mangrove Ecosystem, Maros Regency Herawati, Sari; Rukminasari, Nita; Yunus, Budiman; Alam, Jamaluddin Fitrah
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 02 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss02/585

Abstract

Mangrove ecosystems play an important role in mitigating global warming through their ability to absorb and store carbon in biomass and sediment. This research analyzes the organic carbon content and carbon sequestration potential in mangrove sediments in Bonto Bahari, Maros Regency, South Sulawesi. Using purposive sampling method, sediment samples were taken from 9 points with 5 different depths (0-50 cm) and analyzed using the Loss on Ignition (LOI) method. The results showed very low bulk density values (0.01-0.02 g/cm³) with the highest value at a depth of 20-30 cm. Carbon concentrations were relatively uniform (1.5-2.0%) at all depths with the highest concentration at a depth of 40-50 cm (1.93%). The highest carbon content was found at a depth of 40-50 cm (100.667 tons/ha) with carbon sequestration reaching 516.958 tons/ha, while the lowest value was at a depth of 0-10 cm (24.60 tons/ha). There were significant differences (p<0.05) in carbon content and sequestration between depths of 0-10 cm and 20-30 cm. This research reveals that deeper sediment layers play an important role in carbon storage in mangrove ecosystems, providing significant implications for sustainable mangrove management and local ecosystem-based climate change mitigation efforts
Pre-Study on the Development of Internet of Things-Based Prototype Data Logger for Measuring Heat Sufficiency Number Syukri, Daimon; Rini; Deden Dermawan Septina; Rudi Alfiansyah; Aurelia Amaliyah Tarumiyo; Yasmin Azzahra; Dendi Adi Saputra
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 26 No. 02 (2025): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol26-iss02/586

Abstract

This study aimed to develop an IoT-based data logger prototype to improve data acquisition and monitoring during the sterilization process. Achieving an adequate heat sufficiency value, commonly known as the F0 value, was crucial for effective sterilization, and a thermocouple sensor was typically employed for temperature recording. The research involved designing, constructing, and testing the prototype with a focus on enhancing durability and functionality. Key improvements included adding waterproof sealants to prevent leakage, integrating connectors for enhanced connectivity, and coating the sensor's connector end to ensure long-term performance. Performance evaluation compared the improved IoT data logger with a conventional data logger in terms of heat penetration measurement. Results showed that the IoT prototype recorded heat penetration data with comparable accuracy to the conventional system, confirming its reliability for practical application. The bias for the difference was less than 10%. This innovation demonstrated the potential for improved monitoring in sterilization processes, contributing to enhanced process control and product safety.

Page 28 of 31 | Total Record : 310

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