Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Oto Rhino Laryngologica Indonesiana

orli
Website

Published by Perhimpunan Dokter Spesialis Telinga Hidung dan Tenggorok Bedah Kepala Leher Indonesia

ISSN : 02163667 EISSN : 25983970 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology

Journal Othorhinolaryngologica Indonesiana is a peer-reviewed and open access journal that focuses on promoting otorhinolaryngology-head and neck surgery that publishes research reports, case reports, and literature reviews, to increase knowledge and updating diagnostics procedurs on otorhinolaryngology-head and neck surgery.

Arjuna Subject : -

Articles 493 Documents

11 12 13 14 15

Validitas dan reliabilitas kuesioner Nasal Obstruction Symptom Evaluation (NOSE) dalam Bahasa Indonesia Windy Woro Paramyta; Dini Widiarni; Retno Sulistyo Wardani; Adang Bachtiar
Oto Rhino Laryngologica Indonesiana Vol 47, No 1 (2017): Volume 47, No. 1 January - June 2017
Publisher : PERHATI-KL

Latar belakang: Sumbatan hidung merupakan keluhan yang sering didapatkan pada praktikTelinga Hidung Tenggorok sehari-hari. Penyebab sumbatan hidung adalah multifaktorial, dan dapatdisebabkan oleh faktor struktural ataupun mukosa. Hidung tersumbat juga dapat mengakibatkan gangguankualitas hidup seseorang. Pemeriksaan sumbatan hidung dapat dilakukan secara subjektif dan objektif.Pemeriksaan secara subjektif dapat dilakukan dengan menggunakan kuesioner Nasal Obstruction andSymptom Evaluation (NOSE). Kuesioner ini dapat digunakan untuk menilai sumbatan hidung akibatdeformitas hidung seperti crooked nose, saddle nose, gangguan katup hidung dan deviasi septum.Tujuan: Penelitian ini dilakukan untuk menilai validitas dan reliabilitas kuesioner Nasal Obstructionand Symptom Evaluation (NOSE) dalam Bahasa Indonesia.Metode: Penelitian ini adalah penelitianstudi potong lintang dengan desain deskriptif pada 62 responden.Hasil: Pada uji validitas didapatkanvaliditas internal yang baik pada seluruh pertanyaan, sedangkan uji reliabilitas kuesioner NOSE denganadaptasi Bahasa Indonesia ini mempunyai nilai reliabilitas yang sangat baik dengan nilai Cronbach-α>0,8.Kesimpulan: Kuesioner NOSE dengan adaptasi Bahasa Indonesia adalah valid dan reliabel untukmenilai sumbatan hidung pada deformitas hidung.Kata kunci: Nasal Obstruction Symptom Evaluation, sumbatan hidung, reliabilitas, validitas ABSTRACTBackground: Nasal obstruction is one of the most common symptoms in daily ENT practice.Etiology of nasal obstruction is multifactorial and could be caused by mucosal or structural factors.Nasal obstruction also correlates with quality of life. There are subjective and objective evaluationto diagnose nasal obstruction. Subjective evaluation for nasal obstruction can be assessed by usingNasal Obstruction and Symptom Evaluation (NOSE) Questionnaire. This questionnaire could be usedto assess nasal obstruction caused by nasal deformities such as crooked nose, saddle nose, nasal valvedysfunction and septal deviation. Purpose: To assess the validity and reliability of Nasal Obstructionand Symptom Evaluation (NOSE) Questionnaire in Bahasa Indonesia. Method: This study was a crosssectional descriptive study, involved 62 respondents. Result: Based on the validity of the test, it showedgood internal validity of each question, while on reliability test of NOSE questionnaire was excellentwith values of Cronbach-α >0.8. Conclusion: The Indonesian adaptation of NOSE questionnaire wasfound as valid and reliable instrument for assessing nasal obstruction in nasal deformities.Keywords: Nasal Obstruction Symptom Evaluation, nasal obstruction, reliability, validity

Tatalaksana komprehensif prosedur Millard modifikasi dengan nasoalveolar molding pada labiognatopalatoskizis komplit bilateral Dini Widiarni Widodo; Raden Ayu Anatriera; Taty Zubaidah Cornain
Oto Rhino Laryngologica Indonesiana Vol 48, No 1 (2018): Volume 48, No. 1 January - June 2018
Publisher : PERHATI-KL

Latar belakang: Bibir sumbing dengan celah palatum merupakan suatu kelainan kongenital denganberbagai macam presentasi klinis, bersifat multifactoral inheritance dimana terdapat bakat genetikataupun kontribusi dari faktor lingkungan. Pasien cleft lip palate (CLP) membutuhkan penangananmultidisiplin untuk mengoptimalkan hasil. Penanganan sebelum dan pasca tindakan pembedahan yangkomprehensif diperlukan untuk menghasilkan outcome dan prognosis yang baik. Tujuan: Melaporkankasus labiognatopalatoskizis komplit bilateral dengan pilihan teknik labioplasti modifikasi Millard untukkoreksi primer celah bibir, disertai penggunaan nasoalveolar molding (NAM) sebelum pembedahan.Laporan kasus: Bayi laki-laki berusia 6 bulan datang dengan keluhan terdapat celah pada bibir danpalatum disertai adanya kelainan kongenital multipel sejak lahir. Hasil pemeriksaan fisik didapatkan celahpada bagian atas bibir komplit bilateral, gusi atas, serta palatum. Kavum nasi kedua hidung tampak defekpada bagian dasar hidung. Pada pasien dipasang NAM sejak usia 3 bulan agar dapat membantu asupanmenyusui. Kemudian pasien menjalani tindakan labioplasti menggunakan teknik Millard untuk koreksiprimer celah bibir. Metode: Penelitian literatur dengan mencari melalui Pubmed, Google Scholar, danClinicalKey sesuai pertanyaan klinis dalam beberapa tahun terakhir. Setelah penyaringan dengan kriteriainklusi dan eksklusi, diperoleh 1 jurnal yang relevan, selanjutnya jurnal ini dilakukan pengkajian kritis.Hasil: Dalam jurnal tersebut menyatakan bahwa penggunaan teknik modifikasi Millard dengan penggunaanNAM mempunyai outcome yang baik terhadap perbaikan bentuk bibir dan hidung pasien celah bibirkomplit bilateral. Kesimpulan: Penggunaan nasoalveolar molding sebelum pembedahan dapat bergunamenghasilkan perbaikan bentuk bibir dan hidung serta memperbaiki outcome dan prognosis pasien. ABSTRACTBackground: Cleft lip with cleft palate is either a non-syndromic disorder or a manifestation ofanother syndrome, with a variety of clinical presentations. Non-syndromic cleft lip is a multifactorialinheritance disorder in which there is a genetic tendency in the family, or being contributed byenvironmental factors. Cleft lip and cleft palate (CLP) patients need multidisciplinary managementto optimize results. A comprehensive prior and post surgery treatment are required to produce betteroutcome and prognosis. Objective: Reporting a case of complete bilateral labiognatopalatoschizis withMillard modified labioplasty approach for primary correction and the use of nasoalveolar molding(NAM) prior to surgery. Case Report: A 6-months-old male baby came with a complete bilateral cleftlip and palate, accompanied by multiple congenital abnormalities at birth. Physical examination showedcomplete bilateral cleft along lips, gums, hard and soft palate. There was also a defect at the base of thenose. In this patient, NAM was inserted since 3 months of age to assist breastfeeding intake. The patientunderwent a labioplasty procedure using Millard technique for primary correction of cleft lip. Method:Literature searching through Pubmed, Google Scholar, and ClinicalKey according to clinical questions.After screening with the inclusion and exclusion criteria, one relevant journal was obtained, then criticallyappraised. Result: The journal stated labioplasty procedure with NAM had a good outcome for lip andnose repair in a bilateral complete cleft lip. Conclusion: The use of NAM before surgery could be usefulin improving patient’s outcome and prognosis.

Pengaruh kedalaman dan lama menyelam terhadap ambang-dengar penyelam tradisional dengan barotrauma telinga Arief Tjatur Prasetyo; Joseph Bambang Soemantri; Lukmantya Lukmantya
Oto Rhino Laryngologica Indonesiana Vol 42, No 2 (2012): Volume 42, No. 2 July - December 2012
Publisher : PERHATI-KL

Background: Ear barotrauma is ear tissue damage resulted by the inability to equalize pressure in the middle ear space with the ambient pressure. The greatest relative change in pressure during diving,is near the surface. Ear barotrauma can occur when diving done without equalizing middle ear pressurewith proper procedures. Recurrent ear barotrauma in a long time period can use damage of elastic fibersrecoiling capacity of the tympanic membrane to be irreversible, so it can cause hearing loss. Suddenpressure changes in middle ear space, can be forwarded to the inner ear so it can cause inner eardamage, even deafness. Purpose: This study aims to determine the effect of depth and diving durationto hearing threshold in the traditional divers (divers with diving air compressor tools), who experienced ear barotrauma, and to know the incidence of ear barotrauma. Method: This was an observational analytic study with cross sectional data collection. Data analysis used the cross table, ChiSquare(X2), Spearman correlation and logistic regression test. Result: On October 8 - December 18, 2011 has been conducted a study in traditional divers. 24 samples from 74 population were found. 50 persons with noear barotrauma founds no significant statistic differences with characteristic samples. The results ofChi - Square and Spearman correlationthe showed p=0.350, p=0.382 and p=0.372, p=0.281, which are>a(0.05). The result of logistic regression test showed significancy values were 0.771 and 0.610, whichwere >a(0.05). Ear barotrauma incidence is 32.4%. Conclusion: There is no significant effect of depthand duration of diving to hearing threshold in the traditional divers who experienced ear barotrauma.Ear barotrauma incidence is 32.4%. Keywords: ear barotrauma, diving depth, diving duration, hearing threshold. Abstrak : Latar belakang: Barotrauma telinga adalah kerusakan jaringan telinga akibat ketidak-mampuanmenyamakan tekanan ruang telinga tengah dengan lingkungan. Perubahan tekanan relatif terbesar selamamenyelam terdapat di dekat permukaan. Barotrauma telinga dapat terjadi apabila penyelaman tanpamelaksanakan ekualisasi tekanan telinga tengah dengan cara yang benar. Barotrauma telinga berulangdalam periode lama dapat menyebabkan gangguan kapasitas recoiling serabut elastis membran timpanimenjadi irreversible, sehingga dapat menyebabkan gangguan pendengaran. Perubahan tekanan mendadakdi ruang telinga tengah dapat diteruskan ke telinga dalam sehingga dapat menyebabkan kerusakan telingadalam, bahkan ketulian. Tujuan: Mengetahui pengaruh kedalaman dan lama menyelam terhadap perubahanpendengaran pada penyelam tradisional (penyelam dengan alat bantu selam kompresor udara) yangmengalami barotrauma telinga, serta angka kejadian barotrauma telinga. Metode: Merupakan penelitianobservasional analitik, dengan pengambilan data secara cross sectional. Analisis data menggunakan tabelsilang, uji Chi-Square (X), korelasi Spearman dan regresi logistik. Hasil: Pada Oktober - Desember 2011telah dilakukan penelitian pada penyelam tradisional. Didapatkan 24 sampel dari 74 populasi. Terdapat50 orang tidak mengalami barotrauma telinga, yang tidak terdapat perbedaan statistik signifikan dengankarakteristik sampel. Hasil uji Chi-Square dan korelasi Spearman menunjukkan nilai p=0,350, p=0,382, danp=0,372, p=0,281, yang >a(0,05). Uji regresi logistik menunjukan nilai signifikansi 0,771 dan 0,610, yang>a(0,05). Angka kejadian barotrauma telinga sebesar 32,4%. Kesimpulan: Tidak terdapat pengaruh yangsignifikan kedalaman dan lama menyelam terhadap perubahan pendengaran pada penyelam tradisionalyang mengalami barotrauma telinga. Angka kejadian barotrauma telinga sebesar 32,4%.2 Kata kunci: barotrauma telinga, kedalaman menyelam, lama menyelam, ambang dengar

Risiko terjadinya rinitis akibat kerja pada pekerja yang terpajan debu terigu Emanuel Quadarusman; Sutji Pratiwi Rahardjo; Abdul Qadar Punagi; Riskiana Djamin
Oto Rhino Laryngologica Indonesiana Vol 41, No 1 (2011): Volume 41, No. 1 January - June 2011
Publisher : PERHATI-KL

Background: Occupational rhinitis (OR) may decrease quality of life and productivity, but there is still little information about occupational rhinitis in flour industries. Purpose: To know the influence of atopic history, working duration, work placement and face-mask use in the incidence of occupational rhinitis in wheat flour workers of PT. X in Makassar. Methods: A cross-sectional study on workers in production and packing sections of flour factory X had been conducted. Result: Prevalence of occupational rhinitis in that factory was about 50.7%, and there was a significant relationship between atopic history and work placement with OR incidence (p<0.05). Conclusion: There was a significant relationship between atopic history and work placement with OR incidence, but relationship between OR with working duration and face-mask use could not be established. It was shown that in atopic workers, longer working duration and un-routine use of face-mask increased the risk of OR incidence twice higher. Keywords: occupational rhinitis, flour dust, face mask Abstrak : Latar belakang: Rinitis akibat kerja (RAK) dapat mempengaruhi kualitas hidup pekerja, menghilangkan banyak waktu kerja dan dapat menurunkan produktivitas, namun masih sedikit informasi yang dimiliki mengenai epidemiologi pada industri terigu. Tujuan: Untuk mengetahui pengaruh riwayat atopi, lama bekerja, bagian kerja dan penggunaan masker terhadap kejadian rinitis akibat kerja pada pekerja pabrik terigu X di Makassar. Metode: Suatu studi potong lintang pada pekerja bagian produksi dan pengepakan di pabrik terigu X. Hasil: Didapatkan angka kejadian RAK pada pekerja pabrik adalah 50,7%, dan terdapat hubungan yang bermakna antara atopi dan tempat kerja dengan kejadian RAK (p<0,05). Kesimpulan: Faktor atopi dan tempat kerja dapat mempengaruhi angka kejadian RAK, sedangkan hubungan antara RAK dengan lama kerja dan penggunaan masker belum dapat dibuktikan. Didapati bahwa pada pekerja dengan riwayat penyakit atopi semakin lama masa kerja dan dengan penggunaan masker tidak rutin dapat meningkatkan risiko dua kali lebih tinggi untuk terkena RAK. Kata kunci: rinitis akibat kerja, debu terigu, masker

Kadar reseptor glukokortikoid α dan β pada polip hidung tipe eosinofilik dan tipe neutrofilik Moch Mundir Arif; Rus Suheryanto; Lukmantya Lukmantya; Kenty Wantri Anita
Oto Rhino Laryngologica Indonesiana Vol 44, No 2 (2014): Volume 44, No. 2 July - December 2014
Publisher : PERHATI-KL

Latar Belakang: Penatalaksanaan polip hidung banyak didasarkan pada tipe histopatologinya. Polip hidung tipe eosinofilik lebih sensitif terhadap pemberian kortikosteroid sedang tipe neutrofilik lebih resisten. Hasil pengobatan dengan kortikosteroid juga dipengaruhi oleh reseptor glukokortikoid (GR). Kadar reseptor glukokortikoid β yang tinggi akan lebih resisten dibanding yang rendah. Rasio kadar reseptor glukokortikoid α dan β lebih berperan karena GR β bekerja menghambat GR α. Tujuan: Penelitian ini bertujuan mengetahui hubungan kadar reseptor glukokortikoid α dan β pada polip hidung tipe eosinofilik dan tipe neutrofilik. Metode: Penelitian observasional analitik dengan desain crosssectional. Hasil: Penelitian inimelibatkan 20 penderita polip hidung yang dilakukan biopsi atau operasi. Hasil biopsi atau operasi diperiksa jenis histopatologinya dan dihitung kadar reseptor glukokortikoid α dan β dengan pemeriksaan imunohistokimia. Data penelitian dianalisa dengan uji sampel t tidak berpasangan. Kadar reseptor glukokortikoid α pada polip hidung tipe eosinofilik didapatkan sama dengantipe neutrofilik. Kadar reseptor glukokortikoid β didapatkan lebih tinggi secara bermakna pada polip hidung tipe neutrofilik dibanding tipe eosinofilik. Rasio kadar GRα/GRβ lebih tinggi pada polip hidung tipe eosinofilik dibanding tipe eosinofilik tetapi perbedaannya tidak bermakna. Kesimpulan: penelitian ini kadar reseptor β lebih tinggi pada polip tipe neutrofilik dengan rasio kadar GRα/GRβ lebih tinggi pada polip hidung tipe eosinofilik. Penelitian lebih lanjut diperlukan menghitung kadar reseptor glukokortikoid α dan β lebih akurat dengan menggunakan teknik ELISA (RT-PCR).Kata kunci: Tipe polip hidung, reseptor glukokortikoid, imunohistokimia.ABSTRACTIntroduction: Management of nasal polyps is commonly based on its histopathologic type. Eosinophilic nasal polyps are more sensitive to corticosteroid administration, where as neutrophilic types are more resistant. Results of treatment with corticosteroid were also influenced by glucocorticoid receptor. Higher β Glucocorticoid Receptor (β GR) concentration render more resistency compared with lower one. Ratio of α and β GR was more meaningful because β GR acts to inhibit α GR. Purpose: This study aims todetermine relationship between α and β GR concentration in eosinophilic and neutrophilic nasal polyps. Methods: This is an observational analytic study with cross sectional design. Result: This study involves 20 patients with nasal polyp who underwent biopsy or operation. The biopsy or operation specimenswere then evaluated for its histopathologic type. The concentration of α and β GR was counted by immunohistochemistry. Data was analyzed with unpaired T-test. Concentration of α GR in eosinophilic nasal polyps was similar with neutrophilic type. Concentration of β GR in neutrophilic nasal polyps was significantly higher compared with neutrophilic type. Ratio of α GR/β GR concentration was higher in eosinophilic nasal polyps than eosinophilic, but insignificant. Conclusion: β GR concentration is higher in neutrophilic nasal polyps and ratio of α GR/β GR concentration is higher in eosinophilic nasal polyps. Further study is required to count α GR and β GR concentration more accurately using ELISA (RT-PCR).Keywords: Nasal polyps types, glucocorticoids receptors, immunohistochemistry.

Socioeconomic inequality in stage at diagnosis of nasopharyngeal carcinoma: a cross-sectional study Joko Mulyanto; Anton Budhi Darmawan; Anisa Kapti
Oto Rhino Laryngologica Indonesiana Vol 46, No 1 (2016): Volume 46, No. 1 January - June 2016
Publisher : PERHATI-KL

Background: Nasopharyngeal carcinoma (NPC) is head and neck cancer with the highest incidencein Indonesia, and leads Indonesia as one of the countries with the highest incidence of NPC in the world.Early diagnosis is an important prognostic factor in NPC management. However, most of the NPC patientswere diagnosed at the advanced stage. Delayed diagnosis is contributed by several factors includingsocioeconomic status.Objective: To find out the association between socioeconomic status with stageat diagnosis of NPC patients in Indonesia.Methods: A cross-sectional study was conducted and 57 NPCpatients were consecutively recruited from ENT clinic Margono Soekarjo Hospital as study subjects.Socioeconomic status was measured by income level, educational level, employment status, and healthinsurance coverage. Stages at diagnosis were categorized into early and advanced stage based on theclinical stage. Degree of socioeconomic inequality was analyzed by logistic regression.Results: Incomelevel below poverty line (OR 5.39; 95% CI: 1.36-22.42), basic educational level (OR=3.81; 95% CI:1.11–13.09), currently employed (OR=3.59; 95% CI: 1.07–12.00) had higher probability to be diagnosedat advanced stage. After multivariate analysis, only employment status (OR=5.74; 95% CI: 1.25 – 26.21)contributed significantly to probability of being diagnosed at advanced stage.Conclusion: Socioeconomicstatus was associated with stage diagnosis of NPC levels. Socioeconomic inequality in stage at diagnosisof NPC patients did exist in Indonesia, and employment status was the most contributing factor. Keywords: Socioeconomic status, inequality, stage at diagnosis, nasopharyngeal carcinoma ABSTRAKLatar belakang: Karsinoma nasofaring (KNF) merupakan keganasan kepala leher dengan insidenstertinggi di Indonesia, dan menyebabkan Indonesia menjadi salah satu negara dengan insidens KNFtertinggi di dunia. Diagnosis dini merupakan salah satu faktor prognostik penting dalam penatalaksanaanKNF. Meskipun demikian, sebagian besar pasien KNF didiagnosis pada stadium lanjut. Diagnosisterlambat dipengaruhi oleh berbagai faktor, antara lain status sosial ekonomi. Tujuan: Mengetahuihubungan antara kesenjangan sosial ekonomi dengan stadium diagnosis pasien KNF di Indonesia. Metode:Desain penelitian adalah studi potong lintang, dengan 57 subjek penelitian diambil secara konsekutifdari klinik THT RS Margono Soekarjo. Status sosial ekonomi diukur melalui tingkat penghasilan, tingkatpendidikan, status pekerjaan, dan cakupan asuransi kesehatan. Stadium diagnosis diukur berdasarkanstadium klinis, dan dikategorikan menjadi stadium awal dan stadium lanjut. Tingkat kesenjangan sosialekonomi dianalisis menggunakan regresi logistik. Hasil: Tingkat penghasilan di bawah garis kemiskinan(OR=5,39, CI 95%: 1,31–22.42), tingkat pendidikan dasar (OR=3,81, CI 95%: 1,11–13,09), sedangbekerja (OR=3,59, CI 95%: 1,07–12,00), mempunyai peluang lebih tinggi untuk didiagnosis pada stadiumlanjut. Hasil analisis multivariate menunjukkan hanya status pekerjaan (OR=5,74, CI 95%: 1,25–26,21)yang secara bermakna meningkatkan peluang didiagnosis pada stadium lanjut. Kesimpulan: Status sosialekonomi berhubungan dengan stadium diagnosis pasien KNF di Indonesia. Terdapat kesenjangan sosialekonomi pada stadium diagnosis pasien KNF di Indonesia, dan status pekerjaan merupakan faktor yangmemberikan kontribusi terbesar. Kata kunci: Status sosial ekonomi, kesenjangan, stadium diagnosis, karsinoma nasofaring Author Correspondence: Joko Mulyanto, Department of Public Health and Community MedicineFakultas Kedokteran Universitas Jenderal Soedirman. Email: jkmulyanto@gmail.com.

Peran biofilm bakteri terhadap derajat keparahan rinosinusitis kronis berdasarkan skor Lund-Mackay Dolly Irfandy; Y Yolazenia; Bestari Jaka Budiman; Effy Huriyati; Aziz Djamal; Rizanda Machmud; Dolly Irfandy
Oto Rhino Laryngologica Indonesiana Vol 47, No 2 (2017): Volume 47, No. 2 July - December 2017
Publisher : PERHATI-KL

Latar belakang: Rinosinusitis kronis (RSK) adalah penyakit inflamasi mukosa hidung dan sinus paranasal yang berlangsung lebih dari 12 minggu. Berbagai kondisi telah dikaitkan dengan patogenesis penyakit ini, seperti infeksi bakteri, jamur, superantigen, dan biofilm. Banyak penelitian telah menunjukkan terdapatnya biofilm bakteri pada pasien dengan RSK. Biofilm bakteri dapat memfasilitasi terjadinya resistensi pada antibiotik. CT Scan sinus paranasal (SPN) merupakan pemeriksaan penunjang pilihan untuk diagnosis radiologik RSK. Lund dan Mackay telah mengembangkan suatu sistem berdasarkan skor dari CT Scan SPN untuk menilai kuantifikasi proses peradangan pada sinus paranasal. Beberapa penelitian menunjukkan bahwa pasien dengan biofilm bakteri memiliki skor Lund-Mackay CT Scan SPN yang lebih tinggi pada saat pra operatif. Tujuan: Penelitian ini bertujuan untuk mengetahui peran biofilm bakteri terhadap derajat keparahan RSK berdasarkan skor Lund-Mackay. Metode: Penelitian ini adalah penelitian cross-sectional dengan jumlah total sampel adalah 48 orang pasien RSK. Sekret hidung diambil menggunakan kapas lidi steril dengan swab pada meatus medius lalu dilakukan identifikasi bakteri dan pemeriksaan biofilm dengan tube method. Skor Lund-Mackay dihitung dari CT Scan SPN potongan koronal. Data dianalisis dengan uji Fisher. Hasil: Proporsi pasien RSK dengan skor Lund-Mackay yang tinggi lebih banyak pada pasien dengan biofilm (46,2%), dibandingkan tanpa biofilm (44,4%). Secara statistik tidak terdapat perbedaan bermakna pada skor Lund-Mackay antara pasien dengan biofilm dan tanpa biofilm (p=1,000). Kesimpulan: Tidak terdapat hubungan antara biofilm bakteri dengan derajat keparahan RSK berdasarkan skor Lund-Mackay. Kata Kunci: Rinosinusitis kronis, biofilm bakteri, tube method, skor Lund-Mackay ABSTRACT Background: Chronic rhinosinusitis (CRS) is inflammation of the nose and paranasal sinuses with the symptoms duration more than 12 weeks. Many conditions have been linked to its pathogenesis such as bacterial and fungal infection, superantigens and biofilm. Many studies showed the presence of bacterial biofilms in patients with CRS. Bacterial biofilms can facilitate the resistance to antibiotics. Paranasal sinuses (PNS) CT scan is the method of choice for radiological diagnosis of CRS. Lund and Mackay has developed a scoring system based on the CT finding to assess the quantification of inflammatory process in PNS. Some research suggested that patients with bacterial biofilms have higher Lund-Mackay score pre-operatively. Purpose: To determine the role of bacterial biofilms to the severity of CRS according to Lund-Mackay score. Methods: This was a cross-sectional study with 48 CRS patient’s sample. Nasal discharges were taken by swab in middle meatal using sterile cotton buds, followed by identification of bacteria and detection of bacterial biofilms using tube method. Lund-Mackay score was counted from coronal section of PNS CT Scan. Data was analyzed by Fisher’s exact test. Results: Proportion of patients CRS with high Lund-Mackay score was more common in patient with biofilm (46.2%) compared to patients without biofilm (44.4%). Statistically, there was no significant difference of Lund-Mackay score between patient with biofilm and without biofilm (p=1.00). Conclusion: There was no relationship between the bacterial biofilm with the severity of CRS according to Lund-Mackay score. Keywords: Chronic rhinosinusitis, bacterial biofilm, tube method, Lund-Mackay scores

Nata de coco patch miringoplasti pada ruptur membran timpani Syahrijuita s; Abdul Kadir; Sartini s; Marhaen Hardjo
Oto Rhino Laryngologica Indonesiana Vol 48, No 2 (2018): Volume 48, No. 2 July - December 2018
Publisher : PERHATI-KL

Latar belakang: Patch miringoplasti transkanal yang dapat dilakukan di Poli Klinik Telinga Hidung Tenggorok-Kepala Leher (THT-KL), saat ini merupakan pilihan yang didambakan bagi penatalaksanaan ruptur maupun perforasi membran timpani. Tindakan ini sederhana, praktis, tidak memerlukan alat, dan keterampilan khusus, dan dengan biaya yang murah. Membran yang terbuat dari air kelapa dengan bantuan Acetobacter xylinum yang dikenal dengan sebutan Patch Nata de Coco (PNC) memiliki karakteristik mirip kulit manusia yang elastis, biokompabilitas yang baik, non alergenik, dan dapat disterilkan tanpa merusak sifat fisiknya, direkomendasikan menjadi kandidat patch menggantikan patch kertas. Tujuan: Untuk menilai efek penggunaan PNC sebagai patch miringoplasti secara in vivo dan menilai efeknya terhadap waktu penutupan membran timpani (MT) ayam yang ruptur. Metode: Enam membran timpani ayam petelur dengan umur 72-96 minggu, berat badan 1500-2000 gram, telah dilakukan ruptur sejak 3 hari sebelumnya. Dipasangkan PNC transkanal pada 3 MT dan 3 lainnya dibiarkan tanpa perlakuan. Proses dan waktu penutupan didokumentasikan secara elektronik menggunakan otoskop digital. Hasil: Ruptur MT dengan pemasangan PNC 67% (2MT) menutup pada hari ke-4 dan 100% pada hari ke-5. Ruptur MT tanpa pemasangan PNC (kontrol) 33% (1MT) menutup pada hari ke-8 dan 100% pada hari ke-10. Waktu penutupan ruptur MT dengan pemasangan PNC lebih cepat 2x dibanding ruptur MT tanpa pemasangan PNC (kontrol). Kesimpulan: Patch nata de coco dapat digunakan sebagai patch miringoplasti dan dapat mempercepat penutupan ruptur membran timpani pada ayam. Background: The transcanal miringoplasty patch that can be performed at Ear Nose Throat–Head & Neck Clinic, is currently an ideal choice for the management of rupture and perforation of the tympanic membrane (TM). This procedure is simple, practical, does not require special tools and skill and low cost. The membrane which is made of coconut water processed with Acetobacter xylinum, is known as Nata de Coco Patch (NCP). It has characters of human skin elasticity, good biocompatibility, non-allergenic and can be sterilized without damaging its physical nature. PNC is recommended to be a candidate for replacing the paper patch. Purpose: To evaluate NCP usage in vivo on ruptured chicken TM and the closing time of ruptured TM. Method: Six TM of laying pullet aged 72-96 weeks and body weight 1500-2000 grams were ruptured 3 days previously. Transcanal NCP was installed at 3 perforations, and 3 others were left untreated. The process and TM closuring time was documented electronically using a digital otoscope. Results: Ruptured TM with NCP was closuring 67% (2 TM) on day 4, and total 100% had closured on the 5th day. Ruptured TM without NCP (control) was closuring 33% (1 TM) on day 8, and total 100% had closured on the 10th day. Ruptured TM with NCP closed twice faster than ruptured TM without NCP (control). Conclusion: Nata de coco patch (NCP) can be used as patch miringoplasty, and it accelerates the closure of the ruptured chicken tympanic membrane.

Rekonstruksi deformitas malar pada fraktur lama multipel wajah menggunakan kartilago iga dan silikon Dini Widiarni; Arroyan Wardhana; Endang Mangunkusumo; Yunia Irawati
Oto Rhino Laryngologica Indonesiana Vol 40, No 2 (2010): Volume 40, No. 2 July - December 2010
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v40i2.2

Background: In old traumatic multiple facial fractures, connective tissue and fibrosis were formedwhich make them difficult to be repaired. Purpose: To illustrate to ENT- Head and Neck surgeons asreconstructive surgery could restore the aesthetic and function in facial deformity. Case: Two cases ofold multiple facial fracture were reported. One case was a 32 years old man with history of falling froma tree three years ago and second case was 41 years old man with history of car accident two years ago. Case management: Those two cases were managed with facial reconstruction and malar augmentation using rib cartilage, plate and screw andsilicon implant. Conclusion: Facial reconstruction using rib cartilage autograft, plate and screw or silicon implant could be repair malar asymmetry. Facial analysisin facial reconstruction is important in determining the site of implantation precisely.Keywords: old multiple facial fracture, facial reconstruction, rib cartilage autograft, silicone implant. Abstrak : Latar belakang: Fraktur multipel wajah akibat trauma lama, telah membentuk jaringan ikatdan fibrosis sehingga sukar untuk dilakukan perbaikan. Tujuan: sebagai ilustrasi untuk ahli THT-KL,bagaimana bedah rekonstruksi dapat memperbaiki estetika dan fungsi pada deformitas wajah.Kasus:Dua kasus fraktur lama wajah yaitu, pertama laki-laki berusia 32 tahun dengan riwayat jatuh dari pohon 3 tahun yang lalu dan kasus kedua laki-laki berusia 41 tahun dengan riwayat kecelakaan lalu lintas 2tahun yang lalu.Penatalaksanaan: Pada kedua pasien dilakukan rekonstruksi wajah dengan augmentasimalar menggunakan kartilago iga,plate and screw dan implan silikon. Kesimpulan: Rekonstruksiwajah menggunakan tandur autologus kartilago iga dan plate and screw atau implan silikon dapatmengurangi asimetri malar. Analisis wajah pada saat rekonstruksi penting untuk menentukan posisitandur atau implan dengan tepat.Kata kunci: fraktur multipel lama wajah, rekonstruksi wajah, tandur autologus kartilago iga, implansilikon.

Polipektomi sederhana endoskopik rawat jalan dilanjutkan steroid intranasal sebelum Bedah Sinus Endoskopik Fungsional Retno S. Wardani; Endang Mangunkusumo
Oto Rhino Laryngologica Indonesiana Vol 42, No 1 (2012): Volume 42, No. 1 January - June 2012
Publisher : PERHATI-KL

Background: Functional Endoscopic Sinus Surgery (FESS) is only indicated for nasal polyps (NP) cases which not responsive to maximal medical treatment. Objectives: To find proportion of NPs responsive to maximal medical treatment protocol consisted of office based endoscopic simple polypectomy followed by a 6-week intranasal steroid. Subjects who failed the treatment protocol underwent FESS and followed up until 12 months. The difference of gene expression profile was also evaluated based on their different clinical responses. Method: An experimental study of pre and post self-control to evaluate patients with naïve bilateral nasal polyps who had underwent endoscopic simple polypectomy under local anesthesia followed by intranasal steroid for six weeks. Microarray examination validated by real time RT-PCR was performed to determine the difference of gene expression profile before and after protocol treatment. Result: There were 16 responsive subjects (55.17%) to protocol treatment and 13 unresponsive subjects (44.83%) that subsequently underwent FESS. Twelve months follow up showed recurrent nasal polyps in 5 subjects (17.24%) and no recurrence in 8 subjects (27.6%). F5 gene expression was the determinant in response to protocol treatment, with Exp B=0.042 and p=0.04. Nagelkerke R square value of 49.9% showed the equation of F5 as determinant of reponsiveness.Conclusion: Clinical research of endoscopic simple polypectomy followed by intranasal steroid before FESS intervention in bilateral NP obtained evidence in biomolecular level to gain deeper understanding of how resolution of chronic inflammation happened. Keywords: nasal polyps, endoscopic simple polypectomy, functional endoscopic sinus surgery, F5 gene Abstrak : Latar belakang: Indikasi Bedah Sinus Endoskopik Fungsional (BSEF) pada polip hidung adalah kegagalan respons adekuat setelah terapi medikamentosa maksimal. Tujuan: Mengetahui proporsi penderita polip hidung yang responsif terhadap protokol terapi medikamentosa maksimal dengan polipektomi sederhana endoskopik serta terapi steroid intranasal selama 6 minggu. Pasien yang tidak responsif, menjalani terapi BSEF dan ditindak-lanjuti selama 12 bulan. Juga dievaluasi perbedaan profil ekspresi gen yang mempengaruhi perbedaan respons klinis tersebut. Metode: Desain penelitian adalah eksperimental dengan kontrol sendiri pra dan pasca intervensi polipektomi sederhana endoskopik dan terapi steroid intranasal selama 6 minggu pada penderita polip hidung bilateral. Pemeriksaan microarray yang divalidasi dengan pemeriksaan real time RT-PCR, dilakukan untuk mengetahui perbedaan profil ekspresi gen sebelum dan sesudah protokol terapi. Hasil: Sesudah protokol pengobatan terdapat 16 subjek (55,17%) menunjukkan respons terapi baik, dan 13 subjek (44,83%) dengan tanda klinis menetap atau memburuk, dan selanjutnya menjalani terapi BSEF. Tindak-lanjut selama 1 tahun pasca BSEF pada 13 subjek, didapatkan polip rekurens pada 5 subjek (17,24%) dan tidak ada polip 8 subjek (27,6%). Ekspresi gen F5 adalah variabel yang bermakna dengan nilai Exp B = 0,042 dan p = 0,04. Nilai Nagelkerke R square sebesar 49,9% menunjukkan kekuatan gen F5 sebagai determinan respons kesembuhan. Kesimpulan: Penelitian klinik dengan melakukan tindakan polipektomi sederhana endoskopik dilanjutkan terapi steroid intranasal sebagai terapi lini pertama pada polip hidung sebelum intervensi BSEF, mendapatkan bukti pada tingkat molekuler untuk dapat lebih memahami terjadinya proses resolusi inflamasi kronik. Kata kunci: polip hidung, polipektomi sederhana endoskopik, bedah sinus endoskopik fungsional, gen F5,

Page 13 of 50 | Total Record : 493

11 12 13 14 15

Filter by Year

2004 2025

Filter By Issues

All Issue Vol. 55 No. 2 (2025): VOLUME 55, NO. 2 JULY - DECEMBER 2025 Vol. 55 No. 1 (2025): VOLUME 55, NO. 1 JANUARY - JUNE 2025 Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024 Vol. 54 No. 1 (2024): VOLUME 54, NO. 1 JANUARY - JUNE 2024 Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023 Vol. 53 No. 1 (2023): VOLUME 53, NO. 1 JANUARY - JUNE 2023 Vol 52, No 2 (2022): VOLUME 52, NO. 2 JULY - DECEMBER 2022 Vol. 52 No. 2 (2022): VOLUME 52, NO. 2 JULY - DECEMBER 2022 Vol. 52 No. 1 (2022): VOLUME 52, NO. 1 JANUARY - JUNE 2022 Vol 52, No 1 (2022): VOLUME 52, NO. 1 JANUARY - JUNE 2022 Vol 51, No 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021 Vol. 51 No. 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021 Vol 51, No 1 (2021): Volume 51, No. 1 January - June 2021 Vol. 51 No. 1 (2021): Volume 51, No. 1 January - June 2021 Vol. 50 No. 2 (2020): Volume 50, No. 2 July - December 2020 Vol 50, No 2 (2020): Volume 50, No. 2 July - December 2020 Vol 50, No 1 (2020): Volume 50, No. 1 January - June 2020 Vol. 50 No. 1 (2020): Volume 50, No. 1 January - June 2020 Vol 49, No 1 (2019): Volume 49, No. 1 January-June 2019 Vol 49, No 1 (2019): Volume 49, No. 1 January-June 2019 Vol. 49 No. 1 (2019): Volume 49, No. 1 January-June 2019 Vol 49 (2019): Volume 49, No. 2 July - December 2019 Vol. 49 (2019): Volume 49, No. 2 July - December 2019 Vol 48, No 2 (2018): Volume 48, No. 2 July - December 2018 Vol 48, No 2 (2018): Volume 48, No. 2 July - December 2018 Vol 48, No 1 (2018): Volume 48, No. 1 January - June 2018 Vol 48, No 1 (2018): Volume 48, No. 1 January - June 2018 Vol 47, No 2 (2017): Volume 47, No. 2 July - December 2017 Vol 47, No 2 (2017): Volume 47, No. 2 July - December 2017 Vol 47, No 1 (2017): Volume 47, No. 1 January - June 2017 Vol 47, No 1 (2017): Volume 47, No. 1 January - June 2017 Vol 46, No 2 (2016): Volume 46, No. 2 July - December 2016 Vol 46, No 2 (2016): Volume 46, No. 2 July - December 2016 Vol 46, No 1 (2016): Volume 46, No. 1 January - June 2016 Vol 46, No 1 (2016): Volume 46, No. 1 January - June 2016 Vol. 45 No. 2 (2015): Volume 45, No. 2 July - December 2015 Vol 45, No 2 (2015): Volume 45, No. 2 July - December 2015 Vol 45, No 2 (2015): Volume 45, No. 2 July - December 2015 Vol 45, No 1 (2015): Volume 45, No. 1 January - June 2015 Vol 45, No 1 (2015): Volume 45, No. 1 January - June 2015 Vol 44, No 2 (2014): Volume 44, No. 2 July - December 2014 Vol 44, No 2 (2014): Volume 44, No. 2 July - December 2014 Vol 44, No 1 (2014): Volume 44, No. 1 January - June 2014 Vol 44, No 1 (2014): Volume 44, No. 1 January - June 2014 Vol 43, No 2 (2013): Volume 43, No. 2 July - December 2013 Vol 43, No 2 (2013): Volume 43, No. 2 July - December 2013 Vol 43, No 1 (2013): Volume 43, No. 1 January - June 2013 Vol 43, No 1 (2013): Volume 43, No. 1 January - June 2013 Vol 42, No 2 (2012): Volume 42, No. 2 July - December 2012 Vol 42, No 2 (2012): Volume 42, No. 2 July - December 2012 Vol 42, No 1 (2012): Volume 42, No. 1 January - June 2012 Vol 42, No 1 (2012): Volume 42, No. 1 January - June 2012 Vol 41, No 2 (2011): Volume 41, No. 2 July - December 2011 Vol 41, No 2 (2011): Volume 41, No. 2 July - December 2011 Vol 41, No 1 (2011): Volume 41, No. 1 January - June 2011 Vol 41, No 1 (2011): Volume 41, No. 1 January - June 2011 Vol 40, No 2 (2010): Volume 40, No. 2 July - December 2010 Vol 40, No 2 (2010): Volume 40, No. 2 July - December 2010 Vol 34 (2004): Volume 34, No. 4 October - December 2004 More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Dini Widiarni Widodo

Contact Email
journalorli@gmail.com

Phone
-

Journal Mail Official
journalorli@gmail.com

Editorial Address
-

Location
Unknown,

Unknown

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Dini Widiarni Widodo

Contact Email journalorli@gmail.com

Phone -

Journal Mail Official journalorli@gmail.com

Editorial Address -

Location Unknown, Unknown INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Dini Widiarni Widodo

Contact Email
journalorli@gmail.com

Phone
-

Journal Mail Official
journalorli@gmail.com

Editorial Address
-

Location
Unknown,

Unknown

INDONESIA