Jurnal Biomedika
JURNAL BIOMEDIKA (p-ISSN:1979-035X, e-ISSN: 2302-1306) is a scientific publication media that accommodates the scientific creativity of lecturers and researchers as outlined in scientific writing, both for academics in Setia Budi University and observers of medical biology and health. Articles published are the results of research in the field or in laboratories, scientific studies and studies of books that have never been published in other media. Information on scientific works can range from biotechnology, health, pharmacology, microbiology, biochemistry, and food analysis and health management.
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<![CDATA[AKTIVITAS PENURUNAN PARASITEMIA EKSTRAK KULIT BATANG MUNDU SEBAGAI ANTIPLASMODIUM SECAR in vivo DENGAN PARAMETER ED50 ]]>
<![CDATA[Mamik Ponco Rahayu]]>;
<![CDATA[Reslely Harjanti]]>;
<![CDATA[Gunawan Pamudji]]>
<![CDATA[ Biomedika Vol 7 No 1 (2014): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v7i1.493
<![CDATA[Abstrak Pengobatan malaria di Indonesia saat ini di beberapa daerah masih menggunakan obat standar kloroquin dengan dosis 600 mg hari pertama dan kedua serta 300 mg hari ketiga. Efektivitas pemberian kloroquin saat ini sudah mulai diragukan karena telah banyak ditemukan resistensi terhadap obat ini. Salah satu usaha menemukan antimalaria baru adalah melalui penelitian terhadap tanaman obat yang digunakansecara tradisional oleh masyarakat untuk mengobati malaria. Tanaman mundu termasuk familia garcinia, Marga Garnicia diketahui kaya kandungan senyawa xanton dan menunjukkan aktivitas biologi termasuk antimalaria (Merza, et al.,).Penelitian ini bertujuan untuk mengetahui aktivitas antiplasmodium ekstrak etil asetat kulit batang mundu. Ekstraksi diperoleh secara maserasi bertingkat dengan pelarut n heksan dan etil asetat. Uji aktivitas antiplasmodium dilakukan secara in vivo pada mencit jantan galur Swiss yang diinduksi Plasmodium berghei dengan parameter pengujian persentase parasitemia, persentase penghambatan parasitemia dan penentuan dosis efektif 50% (ED50) menggunakan metode The 4-daySuppresive Test (Peters, 1970). Dosis yang diberikan ke hewan uji untuk ekstrak etil asetat kulit batang mundu yaitu 12,5; 25; 50; 100 mg/gr BB mencit Swiss. Dosis tablet klorokuin 5 mg/kg bb didapatkan 0.91 mg/ 20g bb dan sebagai kontrol normalCMC 0.5%. Pengujian aktivitas antiplasmodium ekstrak etil asetat kulit batang mundu diperoleh dosis ED50 adalah 5,01 mg/kg BB. Berdasarkan data tersebut, ekstrak etil asetat kulit batang mundu memiliki aktivitas antiplasmodium. Keywords: Antiplasmodium, ED50, Kulit batang mundu, etil asetat]]>
<![CDATA[PERSENTASE BAGIAN KARKAS DAN NON KARKAS BROILER DENGAN RANSUM YANG MENGANDUNG LUMPUR DIGESTAT KOTORAN AYAM PETELUR HASIL FERMENTASI KAPANG Aspergillus niger ]]>
<![CDATA[Guruh Sri Pamungkas]]>
<![CDATA[ Biomedika Vol 6 No 1 (2013): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v6i1.244
<![CDATA[Penelitian ini bertujuan untuk mengetahui pengaruh pemberian pakan berupa hasil fermentasi lumpur digester dari kotoran ayam petelur dengan menggunakan kapang Aspergillus niger sebagai fermentornya pada ransum ayam broiler. Penelitian ini menggunakan Rancangan Acak Lengkap dengan 4 kali ulangan dimana tiap- tiap ulangan berisi 4 ekor ayam. Untuk perlakuan pada penelitian ini digunakan 4 perlakuan berupa level pemberian fermentasi lumpur digestat, dimana P0 sebagai kontrol yaitu tanpa pemberian fermentasi lumpur digestat, P1 pemberian fermentasi lumpur digestat 2%, P2 pemberian fermentasi lumpur digestat 4% dan P3 dengan pemberian fermentasi lumpur digestat sebanyak 6%. Sedangkan untuk parameter yang diamati adalah persentase bagian karkas yang meliputi dada, punggung, sayap dan paha. Untuk bagian persentase non karkas yang diamati meliputi: jantung, gizzard (ampela) dan hati. Hasil penelitian menunjukkan bahwa pemberian lumpur digestat fermentasi Aspergillus niger sampai taraf P3 atau 6% tidak berpengaruh nyata (P>0,05) terhadap persentase bagian karkas yang meliputi dada, punggung, sayap dan paha, maupun terhadap presentase bagian non karkas yang meliputi jantung, gizzard,dan hati. Dari hasil penelitian ini dapat disimpulkan bahwa lumpur digester yang difermentasi dengan kapang Aspergillus niger dapat digunakan sampai taraf 6% sebagai ransum ayam broiler.]]>
<![CDATA[Senam Lansia terhadap Penurunan Tekanan Darah pada Lansia ]]>
<![CDATA[Farida Yuliani]]>
<![CDATA[ Biomedika Vol 11 No 2 (2018): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v11i2.404
<![CDATA[Proses kehidupan yang ditandai dengan penurunan kemampuan tubuh untuk beradaptasi dengan stres lingkungan adalah menjadi tua, hal itu merupakan proses alamiah, yang berarti seseorang telah melalui tiga tahap kehidupannya yaitu anak, dewasa dan tua. Bertambahnya umur, fungsi fisiologis mengalami penurunan akibat proses degeneratif. Sehingga memicu terjadinya penyakit degeneratif baik yang menular ataupun tidak. Penyakit tidak menular pada lansia salah satunya adalah hipertensi. Penelitian ini bertujuan untuk mengetahui perbedaan tekanan darah lansia yang diukur setelah melakukan senam di Dusun Tambak Rejo, Desa Gayaman Kecamatan Mojoanyar. Penelitian ini merupakan penelitian analitik. Variabel independen dalam penelitian ini adalah senam lansia, sedangkan variabel dependennya adalah hasil tekanan darah. Populasi dalam penelitian ini adalah semua ibu yang memiliki hipertensi di Dusun Tambak Rejo Desa Gayaman Kecamatan Mojoanyar sebanyak 12 orang. Sampel diambil dengan Total Sampling. Penelitian ini dilakukan pada bulan Agustus 2018. Instrumen yang dipakai adalah checklist dan analisa data menggunakan Paired sample T Test. Hasil penelitian menunjukkan dari 12 responden, sebagian besar responden berusia 40-65 tahun sebanyak 83,4%, dengan hasil rata-rata sistol sebelum senam adalah 151,65 sedangkan sesudah senam didapatkan rata-rata 135.83. Berdasarkan uji Paired Sample T Test didapatkan derajat kemaknaan 0,05 sehingga H ditolak dan H1 diterima artinya 0 ada hubungan senam lansia dengan penurunan tekanan darah sistol. Senam lansia membawa pengaruh yang baik terhadap tekanan darah pada lansia yang hipertensi. Oleh karena itu hasil penelitian ini dapat digunakan sebagai motivasi agar lansia tetap rajin melakukan senam lansia. Saran kita sebagai tenaga kesehatan perlunya menjaga kestabilan tekanan darah dengan rajin melakukan senam lansia disetiap posyandu serta menjaga pola makan dan gaya hidup yang sehat. Kata kunci : Senam lansia, tekanan darah]]>
<![CDATA[PENURUNAN JUMLAH SEL SPERMATOSIT PRIMER DAN SEL SPERMATID TUBULUS SEMINIFERUS MENCIT (Mus musculus) YANG DIBERI EKSTRAK DAUN BELUNTAS (Plucea indica Less) ]]>
<![CDATA[Rizal Maarif Rukmana]]>;
<![CDATA[Bayyinatul Muchtaromah]]>;
<![CDATA[Ahmad Barizi]]>
<![CDATA[ Biomedika Vol 7 No 1 (2014): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v7i1.485
<![CDATA[ABSTRAK Kepadatan penduduk menjadi masalah serius yang dihadapi oleh Indonesia. Angka pertumbuhan penduduk yang tinggi, mempengaruhi tingkat kesejahteraan masyarakat. Salah satu solusi untuk masalah ini yaitu dengan memanfaatkan ekstrak daun beluntas (P. indica Less) sebagai penghambat proses spermatogenesis pada mencit. Penelitian ini menggunakan 25 ekor mencit jantan yang dikelompokkan kedalam 5 kelompok dengan 5 kali ulangan. Ekstrak daun beluntas (P. indicaLess) diberikan dengan dosis 12,5 mg/kg bb, 62,5 mg/kg bb, 125 mg/kg bb, 187,5 mg/kg bb dan kontrol. Setelah 36 hari pemberian ekstrak daun beluntas, mencit dibedah dan diambil testisnya serta di hitung jumlah sel spermatosit primer dan sel spermatid. Data di analisis menggunakan ANOVA satu arah, bila hasil analisis diperoleh nilai Fhitung > Ftabel 1 % maka dilanjutkan uji BNT dengan taraf signifikan 1%. Hasil penelitian menunjukkan bahwa ekstrak daun beluntas mampu menurunkan jumlah sel spermatosit primer, spermatid. Dosis yang paling baik dalam penelitian ini adalah 187,5 mg/kg bb. Kata kunci: Ekstrak daun beluntas, Spermatosit primer, Spermatid, Mus musculus]]>
<![CDATA[Persepsi Ibu Nifas terhadap Pelayanan Kunjungan Nifas ]]>
<![CDATA[Dyah Permata Sari]]>
<![CDATA[ Biomedika Vol 12 No 1 (2019): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v12i1.383
<![CDATA[The covered of porturition service supposed to more than or minimal same with chilbirth by the health staff. Because midewife more active doing the porturition call notiwithstanding to toward woman the chilbirth that helping by indigenous medical practitioner. But a matter of fact that happen about the problem of porturition call that is occur a drop out between the women and Health staf. Because that problem that research done to explaint the perception by women of porturion about porturition call service. The kind of this Research are the descriptif research with quantitative phenomenological. Variabel that researched are perception by women of porturion about porturition call serve. The Population of this Research are all of the women chilbirth in the Puskesmas Sooko Kecamatan Sooko Kabupaten Mojokerto that amount to 20 people. The technical that used is total sampling. This Research did in September 11th – December 4th, 2018. The instrument that used to roundup the file is the kuesioner and the did the processed file that include editing, coding, scoring, tabulating. The result of the Research is almost of the respondent have a positive perception by porturition serve. The observation by age, Education degree, and total of the child, have gotten more of the responden attain the age of 20-35 years old as much as 12 of the respondent (60%). Well educated of the responden are SMP as much as 15 of the respondent (75%), and including by total of the child as much as 14 of the responden have 2 child or for about 70%. Perception is the one of the indicator to explaint how much reaction of responden by the object that Raise in the Research. Result of the Research have indicated that women chilbirth have a positive perception about porturition call service. To advance the orturition call service might as well doing the elaboration intitutionaly]]>
<![CDATA[Pengaruh Pemberian Tablet Ferrum (Fe) dengan Kadar Hemoglobin pada Ibu Hamil Trimester III ]]>
<![CDATA[Liss Dyah Dewi Arini]]>
<![CDATA[ Biomedika Vol 12 No 1 (2019): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v12i1.399
<![CDATA[Anemia has a role as a cause of high maternal and infant mortality. According to Riskesdas in 2018 the prevalence of pregnancy anemia is relatively high, which is 48.9%. From the data in 2018, the highest number of pregnant women who have anemia at the age of 15-24 years is 84.6%, age 25-34 years is 33.7%, age 35-44 years is 33.6%, and age 45 -54 years at 24%. For the treatment, iron tablets are given for 90 days. The results of the 2018 Riskesdas survey the coverage of Fe tablets for pregnant women in Karanganyar district has reached 100%, but the incidence of anemia in pregnant women is still high. The purpose of this study was to determine the effect of consumption of iron tablets (Fe) on hemoglobin (Hb) levels in pregnant women at the Kusumahati Jaten Clinic. The sample used saturated samples and obtained a sample of 30 people. Data collection used guided interviews in third trimester pregnant women and Kusumahati Jaten clinic reports about examining the amount of Fe tablets given to respondents and Hb levels that were first examined before consuming Fe tablets. In addition, direct measurements were taken of the mother's Hb with an Easy Touch tool. Based on the results of the research and discussion that has been described, it can be concluded that there is an influence between iron (Fe) intake and the increase in hemoglobin (Hb) levels in pregnant women in the Kusumahati Jaten clinic, Karanganyar in 2018. in the low category as many as 19 respondents (63%) and the Hb value on the second stage examination showed in the high category as many as 23 respondents (77%). From the results of this study it is expected that pregnant women consume iron tablets according to the prescribed amount.]]>
<![CDATA[Hubungan Motivasi dengan Perilaku Ibu Post Partum dalam Melakukan Mobilisasi Dini ]]>
<![CDATA[Ferilia Adiesti]]>
<![CDATA[ Biomedika Vol 12 No 1 (2019): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v12i1.406
<![CDATA[Bleeding Post-delivery is one of the causes of death in the mother. Which is the most common cause of postpartum bleeding is 50-60% due to muscle weakness or absence of uterine contractions. This can be caused because post partum mothers do not carry out early postpartum mobilization in the first 24 hours after labor and the following days. Analytical design - cross sectional. The number of samples was 28 people and the sampling technique was consecutive sampling. The independent variable is the motivation of post partum mothers to do early mobilization, while the dependent variable is the behavior of post partum mothers in conducting early mobilization, collecting data using a questionnaire. Based on the results of the study that more than 50% of respondents (60%) were not motivated in conducting early mobilization, at most the behavior of post partum mothers doing early mobilization was less than 12 people (48%). The Wilcoxon test results showed that α was smaller than α table is 0,000 <0,05, meaning that there is a relationship between motivation and maternal behavior in carrying out early mobilization. It is expected that midwives can provide information about early mobilization by applying directly and also helping post partum mothers in early mobilization so that post partum mothers are not afraid to carry out early mobilization.]]>
<![CDATA[Isolasi dan Identifikasi Jamur Xerofilik pada Kopi Instant ]]>
<![CDATA[Kartinah Wiryosoendjojo]]>;
<![CDATA[Nony Puspawati]]>;
<![CDATA[Dewi Sulistyawati]]>
<![CDATA[ Biomedika Vol 12 No 1 (2019): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v12i1.411
<![CDATA[The process of producing instant products (including instant coffee) if not properly maintained, can cause microbial contamination which is harmful to health. Microbial contamination can cause diarrhea, poisoning and even death. Some xerophilic molds can produce mycotoxins which can cause poisoning. In this research, it will be investigated whether instant coffee which is marketed in Sleman, Yogyakarta contains xerophilic molds and what are the types. This research is an observational research. Sampling is done randomly. Instant coffee samples taken in the area of Sleman, Yogyakarta consists of 5 instant coffee of various brands. The inoculation was carried out with a sprinkling technique on DG 18 media (Dichloran 18% Glycerol). The results of this study prove that instant coffee in Sleman, Yogyakarta contains xerophilic mushroom spores. The types of xerophilic molds found in instant coffee in Sleman, Yogyakarta are Fusarium culmorum, Aspergillus niger, Curvularia lunata, Cladosporium macrocarpum, Geotrichum candidum.]]>
<![CDATA[Isolasi dan Identifikasi Bakteri Salmonellasp dan Serratia sp Pada Eksoskeleton Lalat Hijau (Chrysomya megacephala) ]]>
<![CDATA[Rizal Maarif Rukmana]]>;
<![CDATA[Rika Siwi Utami]]>
<![CDATA[ Biomedika Vol 12 No 1 (2019): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v12i1.417
<![CDATA[Chrysomyamegacephala is one species that often found around humans, especially in Traditional Markets. Chrysomyamegacephala is one vector of various diseases caused by: bacteria, parasites and helmin. The purpose of this study was to determine whether the exoskeleton of the Chrysomyamegacephala carries the bacteria Salmonellasp and Serratia sp. The method used in catching the Chrysomyamegacephala is by using adhesive bait paper. Number of Chryosomya megacephala samples is 30. Chryosomya megacephalaare then identified. The next step is the isolation of the bacterium Salmonella sp and Serratiasp in the Chrysomyamegacephala using Salmonella Shigella Agar (SSA) and Endo Agar (EA). Identification is done by observing colonies, biochemical tests and gram staining. The results obtained were found in Serratiasp on the exoskeleton of the Chrysomyamegacephalaas much as 90%. Salmonellasp bacteria identified 63.33% on the exoskeleton of the Chrysomyamegacephala. Salmonellasp and Serratiasp bacteria identified in the Chrysomyamegacephala are 30%.Chrysomyamegacephala flies obtained from the Surakarta Mojosongo Market are accepted as vectors of Salmonellasp and Serratia sp.]]>
<![CDATA[Penurunan Kadar Kolesterol Pada Kuning Telur Asin dengan Perendaman Seduhan Serbuk dan Ekstrak Daun Salam (Syzygium Polyanthum) dengan Variasi Lama Perendaman ]]>
<![CDATA[Kiky Candrawati]]>;
<![CDATA[Nur Hidayati]]>
<![CDATA[ Biomedika Vol 12 No 1 (2019): Jurnal Biomedika ]]>
Publisher : <![CDATA[Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta ]]>
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DOI: 10.31001/biomedika.v12i1.418
<![CDATA[Egg has a good nutrient, but egg yolk also has high cholesterol so if we eat it excessive, it will do serious damage in our body and increasing the risk of coronary heart disease. Therefore, needed an inovation in food processing industry to process healthier foods and low cholesterol. One of the way by decreasing cholesterol levels in egg yolk by bay leaf (Syzygium polyanthum). Extract and powder of bay leaf (Syzygium polyanthum) were made to decreasing cholesterol levelsin egg yolk. After that, extract and powder solution of bay leaf were made with 2% of consentration. Uncooked eggswere soaking at extract and powder solution for 12 and 24 hours. Then, uncooked eggs were steam and do cholesterol examination with “CHOD-PAP” method and also do organoleptictesting involving 30 panelist. The result showed that soaking with extract of bay leaf for 24 hoursshowed higher decreasing cholesterol levelswhich has measured of 231 mg/100g. Cholesterol levels of egg before soaking knowing which has measured of 621 mg/100g, so that the percentage of decline is 62,80%. Statistic analysis with two ways ANOVA showed that there is a significant different in cholesterol levels. Organoleptic testinghas showed if consumen like the egg.]]>
